WO2012157221A1 - Dispositif de génération d'images tomographiques, procédé, et programme - Google Patents

Dispositif de génération d'images tomographiques, procédé, et programme Download PDF

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Publication number
WO2012157221A1
WO2012157221A1 PCT/JP2012/003059 JP2012003059W WO2012157221A1 WO 2012157221 A1 WO2012157221 A1 WO 2012157221A1 JP 2012003059 W JP2012003059 W JP 2012003059W WO 2012157221 A1 WO2012157221 A1 WO 2012157221A1
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Prior art keywords
acoustic wave
image
range
photoacoustic
light irradiation
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PCT/JP2012/003059
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English (en)
Japanese (ja)
Inventor
佐藤　良彰
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富士フイルム株式会社
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Publication of WO2012157221A1 publication Critical patent/WO2012157221A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13—Tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements

Definitions

  • the present invention relates to a tomographic image generation apparatus and method, and more particularly to a tomographic image generation apparatus and method for generating an ultrasonic image based on reflected ultrasonic waves and a photoacoustic image based on photoacoustic signals.
  • An ultrasonic inspection method is known as a kind of image inspection method capable of non-invasively examining the state inside a living body.
  • an ultrasonic probe capable of transmitting and receiving ultrasonic waves is used.
  • the ultrasonic waves travel inside the living body and are reflected at the tissue interface.
  • the internal state can be imaged.
  • an object of the present invention is to provide a tomographic image generation apparatus, method, and program capable of suppressing unnecessary laser emission when generating a photoacoustic image within a certain predetermined range.
  • the present invention provides a light source unit, a light irradiation unit for irradiating light emitted from the light source unit toward a subject in a predetermined light irradiation range, and an acoustic wave for the subject.
  • Acoustic wave transmitting means for transmitting, photoacoustic wave generated in the subject by light irradiation, and acoustic wave detecting means for detecting reflected acoustic wave with respect to the transmitted acoustic wave, and reflection detected by the acoustic wave detecting means Based on the acoustic wave, a reflected acoustic wave image generation unit that generates a reflected acoustic wave image in a range wider than the light irradiation range, and a photoacoustic image is generated in the reflected acoustic wave generated by the reflected acoustic wave image generation unit.
  • a light irradiation range setting unit for setting a power range, a light irradiation range control unit for controlling the light irradiation unit so that light is emitted from the light irradiation unit toward the range set by the light irradiation range setting unit, and an acoustic Photoacoustic wave detected by wave detection means Based on, providing a tomographic image generating apparatus according to claim in a range where the light irradiation range setting means has set that a photoacoustic image generating means for generating photoacoustic images.
  • the light irradiation range setting means sets a range in which a photoacoustic image is to be generated based on the reflected acoustic wave image generated by the reflected acoustic wave image generation means.
  • the light irradiation range setting means refers to a table that stores the observation target and the extraction condition from the reflected acoustic wave image of the observation target in association with each other, and based on the extraction condition corresponding to the observation target specified by the user Then, an observation target may be extracted from the reflected acoustic wave image, and a range including the extracted position of the observation target may be set as a range where a photoacoustic image is to be generated.
  • the reflected acoustic wave image generation unit generates a reflected acoustic wave image based on the reflected acoustic wave detected by performing sector scanning, and the photoacoustic image generation unit falls within the range set by the light irradiation range setting unit. Thus, the scanning line is scanned to generate a photoacoustic image.
  • the light irradiating unit is composed of an output end of an optical fiber that guides light from the light source unit, and the light irradiation range control means controls the light control unit by displacing the output end of the optical fiber. Good.
  • the generated photoacoustic image and the reflected acoustic wave image may be displayed side by side or synthesized.
  • the detector element of the acoustic wave detecting means may also serve as the transmitter element of the acoustic wave transmitting means.
  • the tomographic image generation apparatus of the present invention further includes a position sensor for detecting the position of the acoustic wave detection means, and a position measurement means for measuring the position of the acoustic wave detection means based on a signal from the position sensor. can do.
  • At least one of the photoacoustic image generation unit and the ultrasonic image generation unit uses the position of the acoustic wave detection unit at the time of acoustic wave detection measured by the position measurement unit, and the three-dimensional image Data may be generated.
  • the present invention also includes a step of transmitting an acoustic wave to the subject and detecting a reflected acoustic wave with respect to the transmitted acoustic wave; Generating a reflected acoustic wave image based on the detected reflected acoustic wave; In the generated reflected acoustic wave image, setting a range in which a photoacoustic image should be generated in a narrower range than the reflected acoustic wave image; Irradiating the subject with light toward a set range; Detecting a photoacoustic wave generated in the subject by light irradiation; And a step of generating a photoacoustic image in a set range based on the detected photoacoustic wave.
  • the present invention further includes a step of generating a reflected acoustic wave image based on a detection result of the reflected acoustic wave with respect to the acoustic wave transmitted into the subject, and the reflected acoustic wave image is generated in the generated reflected acoustic wave image.
  • the tomographic image generation apparatus, method, and program of the present invention set a light irradiation range narrower than the image range of the ultrasonic image in the ultrasonic image, and irradiate the set range with laser light to produce a photoacoustic image. Is generated.
  • the ultrasound image By using the ultrasound image, the position of the region of interest in the subject can be specified, and the region of interest is photoacoustic by controlling the light irradiation unit so that the region of interest enters the light irradiation range. Can be imaged with images.
  • FIG. 1 is a block diagram showing a tomographic image generation device according to a first embodiment of the present invention.
  • the block diagram which shows the production
  • the block diagram which shows the production
  • the figure which shows the example of a display screen at the time of the setting of light irradiation range.
  • the wave form diagram which shows the phase matching addition of a photoacoustic signal.
  • the flowchart which shows an operation
  • the block diagram which shows the tomographic image generation apparatus of 2nd Embodiment of this invention.
  • FIG. 1 shows a tomographic image generation apparatus according to a first embodiment of the present invention.
  • the tomographic image generation apparatus 10 includes a probe 11, a light source (light source unit) 12, a transmission circuit 13, a reception circuit 14, an AD converter 15, an ultrasonic image generation unit 16, a photoacoustic image generation unit 17, an image synthesis unit 18, and an image display.
  • Means 19 light irradiation range setting means 20, fiber position control means 21, fiber position control motor 22, CPU 24, timing control means 25, and operation unit 26 are provided.
  • the light source 12 is configured as a laser light source, for example, and emits light to be irradiated on the subject. What is necessary is just to set the wavelength of a laser beam suitably according to an observation target object.
  • the laser light emitted from the light source 12 is guided to the vicinity of the surface of the subject using light guiding means such as an optical fiber 23, for example.
  • the end of the optical fiber 23 constitutes a light irradiating unit that irradiates the subject with laser light, and the guided laser light irradiates the subject within a predetermined light irradiation range from the emission end of the optical fiber 23. Is done.
  • the laser beam emitted from the emission end of the optical fiber 23 is irradiated to the subject with a predetermined spread.
  • the fiber position control motor 22 displaces the direction of the emission end of the optical fiber 23 to change the emission direction of the laser light.
  • the probe (acoustic wave detecting means) 11 outputs (transmits) an acoustic wave (typically, an ultrasonic wave) to the subject, and acoustics for detecting (receiving) the acoustic wave from the subject.
  • Wave detecting means The detector element of the acoustic wave detecting means may also serve as the transmitter element of the acoustic wave transmitting means. That is, one element may be used for both transmission and reception of acoustic waves.
  • the acoustic wave detecting means and the acoustic wave transmitting means are not necessarily provided in the same probe, and a configuration in which the acoustic wave detecting means and the acoustic wave transmitting means are placed at different positions is possible.
  • the probe 11 has, for example, a plurality of ultrasonic transducers arranged one-dimensionally as a detector element of the acoustic wave detecting means and a transmitter element of the acoustic wave transmitting means.
  • Each ultrasonic transducer detects a photoacoustic wave generated when the measurement object in the subject absorbs the laser light from the light source 12 after the subject is irradiated with the laser beam.
  • Each ultrasonic transducer outputs an ultrasonic wave toward the inside of the subject and detects a reflected ultrasonic wave (reflected acoustic wave) with respect to the transmitted ultrasonic wave.
  • a sector scanning type ultrasonic probe can be used as the probe 11, for example.
  • the type of the probe 11 is not particularly limited, and the probe 11 may be a transvaginal or transrectal probe, or may be a microconvex type probe used for an ultrasonic endoscope.
  • the ultrasonic image generation means 16 generates a reflected acoustic wave image (ultrasonic image) based on a detection signal (hereinafter also referred to as a reflected acoustic signal) of the reflected acoustic wave detected by the probe 11.
  • the photoacoustic image generation means 17 generates a photoacoustic image based on a photoacoustic wave detection signal (hereinafter also referred to as a photoacoustic signal) detected by the probe 11.
  • the ultrasonic image generation unit 16 generates an ultrasonic image in a wider range than the irradiation range of the laser light irradiated from the light irradiation unit when generating the photoacoustic image.
  • the photoacoustic image generation means 17 generates a photoacoustic image in a range corresponding to the irradiation range of the laser light.
  • the range imaged by the photoacoustic image is narrower than the range imaged by the ultrasonic image.
  • the ultrasonic image generation unit 16 includes a phase matching unit 161 and an image construction unit 162.
  • the phase matching unit 161 performs phase matching addition of the reflected acoustic signals detected by the plurality of ultrasonic transducers of the probe 11. For example, the phase matching unit 161 adds the reflected acoustic signals from the 64ch ultrasonic transducers of the probe 11 while delaying them by a delay time corresponding to the position of the ultrasonic transducers. By performing the phase matching addition, an image signal for one scanning line is generated.
  • the image construction unit 162 generates an ultrasonic image after performing, for example, detection and logarithmic conversion on the image signal of each line subjected to phase matching addition.
  • the photoacoustic image generation means 17 includes a phase matching means 171 and an image construction means 172.
  • the phase matching unit 171 performs phase matching addition of the photoacoustic signals detected by the plurality of ultrasonic transducers of the probe 11. For example, the phase matching unit 171 adds the photoacoustic signals from the ultrasonic transducers for 64 channels included in the probe 11 while delaying them by a delay time corresponding to the position of the ultrasonic transducers. By performing the phase matching addition, an image signal for one scanning line is generated.
  • the image construction unit 172 generates a photoacoustic image after performing, for example, detection and logarithmic conversion on the image signal of each line.
  • the image synthesizing unit 18 synthesizes the ultrasonic image generated by the ultrasonic image generating unit 16 and the photoacoustic image generated by the photoacoustic image generating unit 17.
  • the image composition unit 18 performs image composition by superimposing a photoacoustic image on an ultrasonic image, for example.
  • the image display means 19 displays the image synthesized by the image synthesis means 18 on a display monitor or the like. Alternatively, the ultrasonic image and the photoacoustic image may be switched and displayed on the image display means 19 without performing image synthesis, or the photoacoustic image and the ultrasonic image may be displayed side by side at the same time.
  • the light irradiation range setting unit 20 sets a range in which a photoacoustic image should be generated in the ultrasonic image generated by the ultrasonic image generation unit 16. For example, the light irradiation range setting unit 20 displays the light irradiation range irradiated with the laser light from the light irradiation unit on the ultrasonic image generated by the ultrasonic image generation unit 16 and generates a photoacoustic image to the user. Encourage the setting of the range to be performed. For example, the user operates a pointing device such as a trackball included in the operation unit 26 to move the light irradiation range (a range where a photoacoustic image is generated). The light irradiation range setting means 20 moves the position of the light irradiation range to be displayed in accordance with a user operation.
  • a pointing device such as a trackball included in the operation unit 26 to move the light irradiation range (a range where a photoacoustic image is generated).
  • the fiber position control unit 21 is a light irradiation range control unit, and controls the light irradiation unit so that the laser beam is irradiated from the light irradiation unit toward the range set by the light irradiation range setting unit 20.
  • the fiber position control means 21 drives the fiber position control motor 22, for example, to displace the emission end of the optical fiber 23 that is the light irradiation unit, and controls the traveling direction of the laser light emitted from the light irradiation unit.
  • a CPU (Central Processing Unit) 24 controls each unit in the tomographic image generation apparatus 10.
  • the timing control means 25 controls the emission timing of the laser light, the timing of transmitting ultrasonic waves from the probe 11 to the subject, the sampling start timing in the AD converter 15, and the like.
  • the ultrasonic image generation unit 16, the photoacoustic image generation unit 17, the image synthesis unit 18, the light irradiation range setting unit 20, the fiber position control unit 21, and the timing control unit 25 are realized by hardware different from the CPU 24. There is no need, and the functions of these means may be realized by the CPU 24 executing processing according to a predetermined program.
  • the timing control means 25 instructs the transmission circuit to transmit ultrasonic waves and instructs the AD converter 15 to start sampling of the reflected acoustic signal, for example, in a frame for generating an ultrasonic image. Further, after detecting the reflected acoustic signal, the ultrasonic image generating means 16 is instructed to generate an ultrasonic image. On the other hand, in the frame for generating the photoacoustic image, the light source 12 is instructed to irradiate the laser beam, and the AD converter 15 is instructed to start sampling of the photoacoustic signal in accordance with the emission timing of the laser beam. Further, after the photoacoustic signal is detected, the photoacoustic image generation unit 17 is instructed to generate a photoacoustic image.
  • FIG. 2A and 2B show an ultrasonic image generation range and a photoacoustic image generation range.
  • 2A is a front view and FIG. 2B is a side view.
  • the probe 11 has, for example, 64 ultrasonic transducers CH0 to CH63 arranged one-dimensionally.
  • sector scanning is performed by causing each ultrasonic transducer to transmit ultrasonic waves with a time difference.
  • the ultrasonic image generation means 16 generates an ultrasonic image for a range shown as an image range 30 in FIG. 2A based on the reflected acoustic signal detected by performing sector scanning.
  • the direction of the tip (outgoing end) of the optical fiber 23 that constitutes the light irradiating portion can be displaced by driving the fiber position control motor 22, and the irradiation range of the laser light can be changed according to the orientation of the emitting end. Can be changed.
  • the range irradiated with the laser light is narrower than the image range 30 of the ultrasonic image, as shown as a light irradiation range 31 in FIG. 2A.
  • the range in which the laser beam is irradiated matches the range in which the photoacoustic image is generated. That is, the light irradiation range 31 represents the image range of the photoacoustic image.
  • the user specifies the position of the part to be observed from the photoacoustic image by referring to the displayed ultrasonic image, for example.
  • the region 32 of the measurement object that is the region of interest is partly out of the current light irradiation range 31.
  • the user operates the trackball of the operation unit 26 to move the light irradiation range 31 so that the region of interest is irradiated with the laser light.
  • FIG. 3 shows an example of a display screen when setting the light irradiation range.
  • the user operates a trackball or the like according to the direction in which the light irradiation range is desired to be moved.
  • the light irradiation range setting means 20 drives the fiber position control motor 22 via the fiber position control means 21 according to the user operation, and changes the light irradiation range. Further, the light irradiation range setting means 20 moves the graphic display representing the light irradiation range 31 displayed on the ultrasonic image in correspondence with the movement of the light irradiation range.
  • the user confirms that the region of interest 32 enters the light irradiation range 31 on the display screen, and operates a predetermined key to determine the light irradiation range.
  • the light irradiation range setting means 20 notifies the CPU 24 of the spatial position information of the light irradiation range determined by the user.
  • the CPU 24 notifies the photoacoustic image generation means 17 of the spatial position information of the determined light irradiation range, in other words, the spatial position information of the range where the photoacoustic image is to be generated.
  • the photoacoustic image generation means 17 scans a scanning line within the range set by the light irradiation range setting means 20, for example, and generates a photoacoustic image.
  • FIG. 4 is a timing chart showing an operation example.
  • the timing control means 25 generates a frame synchronization signal (a) under the control of the CPU 24.
  • the timing control means 25 generates an ultrasonic image or a photoacoustic image in synchronization with the frame synchronization signal (a).
  • the ratio between the frame that generates the ultrasonic image and the frame that generates the photoacoustic image may be arbitrary.
  • the timing control unit 25 instructs the transmission circuit 13 to transmit an ultrasonic wave and instructs the reception circuit 14 to receive a reflected ultrasonic wave in a frame for generating an ultrasonic image.
  • the AD converter 15 is instructed to start sampling of reflected ultrasonic waves received by the receiving circuit 14.
  • FIG. 5 shows scanning lines when generating a photoacoustic image.
  • the probe 11 has, for example, 64 ultrasonic transducers. It is assumed that the rightmost side is CH0 and the leftmost side is CH63.
  • the photoacoustic image generation means 17 sets, for example, a scanning line passing through the center of 64 ultrasonic transducers within the light irradiation range 31, and adds 64 ch of photoacoustic signals in phase matching for each scanning line.
  • FIG. 6 shows the phase matching addition of the photoacoustic signal.
  • the time is t
  • the delay amount corresponding to the position of the ultrasonic transducer is tdlyi (i is a channel number 0 to 63). It can be expressed as
  • phase matching addition including electronic steering is performed.
  • the scanning line is steered toward the light absorber.
  • the delay amount (tdly0) on the CH0 side is larger than the delay amount (tdly63) on the CH63 side.
  • phase matching addition in ultrasonic image generation is the same process as phase matching addition in photoacoustic image generation.
  • the phase matching addition is performed in consideration of the delay amount for the return path distance (one way), whereas in the ultrasonic image generation, the phase matching addition is performed in consideration of the delay amount of the round trip distance.
  • the timing control means 25 After setting the light irradiation range, the timing control means 25 sends a light emission command to the light source 12 according to an instruction from the CPU 24.
  • the light source 12 When receiving the light emission command, the light source 12 emits a laser beam after a predetermined time has elapsed. The emitted laser light is applied to the subject from the emission end of the optical fiber 23 (step S8).
  • the receiving circuit 14 receives the photoacoustic signal detected by each ultrasonic transducer of the probe 11, and the AD converter 15 performs AD conversion on the received photoacoustic signal (step S9).
  • an ultrasonic image is generated before generating a photoacoustic image, and a light irradiation range narrower than the image range of the ultrasonic image is set in the ultrasonic image.
  • laser light is irradiated to the light irradiation range set using the ultrasonic image, and the photoacoustic image is generated within the range.
  • the ultrasound image confirm the position of the region of interest to be observed with the photoacoustic image, and set the light irradiation range so that the region of interest is included in the light irradiation range. Can be imaged with images.
  • the user can grasp the positional relationship between the light irradiation range and the region of interest while The irradiation range can be adjusted.
  • the laser of the laser light emitted from the light source 12 is used. It is necessary to increase power. Considering damage to the optical fiber 23 and power consumption, it is not preferable to use a high-power laser beam. In the present embodiment, since the light irradiation range is narrower than the image range of the ultrasonic image, it is not necessary to enter high-power laser light into the optical fiber 23, and damage to the optical fiber 23 can be suppressed. Power consumption can be reduced.
  • the image range of the photoacoustic image is narrowed. If the image range of the photoacoustic image is narrower than the image range of the ultrasonic image, the region of interest that can be observed in the ultrasonic image cannot be observed in the photoacoustic image unless the light irradiation range is set appropriately.
  • the region of interest can be obtained without repeatedly performing laser light irradiation and photoacoustic image generation while moving the ultrasonic probe. Can be irradiated with laser light.
  • the region of interest can be easily irradiated with laser light, unnecessary laser emission when the region of interest is imaged with a photoacoustic image can be suppressed.
  • the light irradiation range setting unit 20 has been described as setting the light irradiation range in accordance with a user operation. Instead, the light irradiation range setting unit 20 includes an ultrasonic image or an image thereof. A light irradiation range (a range in which a photoacoustic image is to be generated) may be set based on the reflected ultrasound of the generation source. For example, the light irradiation range setting unit 20 may extract a region of interest based on the pixel value (luminance value) of the ultrasound image, and set a range including the extracted position of the region of interest as the light irradiation range.
  • a light irradiation range a range in which a photoacoustic image is to be generated
  • the light irradiation range setting unit 20 may extract a region of interest based on the pixel value (luminance value) of the ultrasound image, and set a range including the extracted position of the region of interest as the light irradiation range.
  • the light irradiation range setting means 20 may detect a Doppler component from the reflected ultrasonic wave and set a range including a region where a large Doppler component is detected as the light irradiation range. The user can set (select) how the light irradiation range setting means 20 sets the light irradiation range based on the ultrasonic image.
  • the light irradiation range setting means 20 may use a table for storing an observation target and an extraction condition from the ultrasonic image of the observation target in association with each other when extracting the region of interest from the ultrasonic image. For example, for the observation target “cyst”, “low echo part in medium luminance tissue part” is registered in the table as an extraction condition, and for the observation target “tumor”, “high echo part in medium luminance tissue part” "Is registered in the table as an extraction condition.
  • the light irradiation range setting unit 20 reads out the extraction condition corresponding to the designated observation target from the table, and extracts the observation target from the ultrasonic image according to the read out extraction condition.
  • the corresponding extraction condition “low echo part in medium luminance tissue part” is read, and the “cyst” part is extracted from the ultrasound image according to the extraction condition .
  • the user may arbitrarily adjust the light irradiation range with respect to the light irradiation range automatically set by the light irradiation range setting means 20.
  • FIG. 8 shows a tomographic image generation apparatus according to the second embodiment of the present invention.
  • the tomographic image generation apparatus 10a of the present embodiment further includes a position sensor 27 and a position measurement unit 28 in addition to the configuration of the tomographic image generation apparatus 10 of the first embodiment shown in FIG.
  • the position sensor 27 is a sensor for detecting the position of the probe 11.
  • a magnetic sensor can be used as the position sensor 27.
  • the position measuring unit 28 measures the position of the probe 11 when detecting an acoustic wave (photoacoustic wave or reflected acoustic wave) based on a signal from the position sensor 27.
  • the probe 11 includes an acoustic wave detection unit 11a and an acoustic wave transmission unit 11b.
  • an element such as PVDF (polyvinylidene fluoride) having a wide reception band for photoacoustics is used.
  • an element such as PZT (lead zirconate titanate) is used for the acoustic wave transmitting means 11b.
  • the position sensor 27 may be attached to the acoustic wave detection unit 11a.
  • At least one of the ultrasonic image generation unit 16 and the photoacoustic image generation unit 27 uses a position information of the acoustic wave detection unit 11a at the time of acoustic wave detection measured by the position measurement unit 28 to obtain a three-dimensional image.
  • Data volume data
  • the position information measured by the position measuring unit 28 is input to the CPU 24.
  • the CPU 24 causes the ultrasonic image generating unit 16 and the photoacoustic image generating unit 17 to detect a plurality of ultrasonic images and photoacoustic images at the time of acoustic wave detection.
  • the acoustic wave detection means 11a is controlled to be coupled according to the position.
  • the three-dimensional image data of a photoacoustic image and an ultrasonic image can be produced
  • the ultrasonic image generation unit 16 and the photoacoustic image generation unit 17 may generate three-dimensional image data in real time in synchronization with the scanning of the probe 11. Alternatively, the three-dimensional image data may be generated after the detection target space has been scanned.
  • the light source 12 is configured to be able to emit laser beams having a plurality of different wavelengths.
  • the operation unit 26 is provided with a wavelength selection switch for receiving, for example, a wavelength selection operation.
  • the user can select the wavelength of the laser beam irradiated on the subject from a plurality of wavelengths that can be emitted by the light source 12 by operating a wavelength selection switch provided in the operation unit 26.
  • the user selects a laser wavelength according to, for example, the observation target region and the type of functional image desired to be used.
  • the light irradiation range setting unit 20 may set a light irradiation range for each wavelength.
  • the tomographic image generation apparatus, method, and program according to the present invention are not limited to the above embodiment, and various configurations are possible from the configuration of the above embodiment. Those modified and changed as described above are also included in the scope of the present invention.

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Abstract

La présente invention vise à supprimer l'émission laser non souhaitée lors de la génération d'une image photoacoustique dans une plage prescrite. La présente invention concerne par conséquent un moyen de génération d'images ultrasonores (16) qui génère une image ultrasonore basée sur des ondes ultrasonores réfléchies détectées par une sonde (11). Sur l'image ultrasonore, un moyen de définition de plage d'éclairage optique (20) qui définit une plage d'éclairage optique qui est plus étroite que la plage de l'image. Un moyen de régulation de la position de fibre (21) régule la direction de l'extrémité d'émission d'une fibre optique (23) par entraînement d'un moteur de régulation de la position de fibre (22). La lumière laser émise d'une source de lumière (12) est dirigée de l'extrémité d'émission de la fibre optique (23) en direction d'un sujet à détecter dans une plage d'éclairage optique prescrite. Un moyen de génération d'image photoacoustique (17) génère une image photoacoustique dans la plage qui a été définie par le moyen de définition de la plage d'éclairage optique (20), en se basant sur le signal photoacoustique détecté par la sonde (11).
PCT/JP2012/003059 2011-05-13 2012-05-10 Dispositif de génération d'images tomographiques, procédé, et programme WO2012157221A1 (fr)

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JP2011-107766 2011-05-13
JP2012098320A JP5681141B2 (ja) 2011-05-13 2012-04-24 断層画像生成装置、方法、及びプログラム
JP2012-098320 2012-04-24

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WO2014156408A1 (fr) * 2013-03-26 2014-10-02 Canon Kabushiki Kaisha Appareil d'acquisition d'information d'objet et son procédé de commande
JP2018089346A (ja) * 2016-11-25 2018-06-14 キヤノン株式会社 光音響装置、画像表示方法、プログラム
US20210275040A1 (en) * 2020-03-05 2021-09-09 Koninklijke Philips N.V. Ultrasound-based guidance for photoacoustic measurements and associated devices, systems, and methods

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WO2016070115A1 (fr) * 2014-10-30 2016-05-06 Seno Medical Instruments, Inc. Système d'imagerie opto-acoustique avec détection de l'orientation relative de source de lumière et de récepteur acoustique au moyen d'ondes acoustiques
EP3415097B1 (fr) 2016-02-08 2020-07-15 FUJIFILM Corporation Dispositif de génération d'image d'onde acoustique et procédé de génération d'image d'onde acoustique
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