WO2012153348A3 - Process for preparation of prasugrel and its intermediates - Google Patents

Process for preparation of prasugrel and its intermediates Download PDF

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Publication number
WO2012153348A3
WO2012153348A3 PCT/IN2012/000327 IN2012000327W WO2012153348A3 WO 2012153348 A3 WO2012153348 A3 WO 2012153348A3 IN 2012000327 W IN2012000327 W IN 2012000327W WO 2012153348 A3 WO2012153348 A3 WO 2012153348A3
Authority
WO
WIPO (PCT)
Prior art keywords
intermediates
prasugrel
preparation
pharmaceutically acceptable
pharmaceutical compositions
Prior art date
Application number
PCT/IN2012/000327
Other languages
French (fr)
Other versions
WO2012153348A2 (en
Inventor
Dattatray Shivaji SHEJUL
Sanjay S. BHISE
Srinivas Reddy Sanikommu
Tarun Kant Sharma
Milind Gharpure
Original Assignee
Glenmark Generics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Limited filed Critical Glenmark Generics Limited
Publication of WO2012153348A2 publication Critical patent/WO2012153348A2/en
Publication of WO2012153348A3 publication Critical patent/WO2012153348A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Provided is a process for preparing prasugrel, its intermediates, and pharmaceutically acceptable salts and pharmaceutical compositions thereof.
PCT/IN2012/000327 2011-05-09 2012-05-02 Process for preparation of prasugrel and its intermediates WO2012153348A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1430/MUM/2011 2011-05-09
IN1430MU2011 2011-05-09

Publications (2)

Publication Number Publication Date
WO2012153348A2 WO2012153348A2 (en) 2012-11-15
WO2012153348A3 true WO2012153348A3 (en) 2013-03-21

Family

ID=47139756

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000327 WO2012153348A2 (en) 2011-05-09 2012-05-02 Process for preparation of prasugrel and its intermediates

Country Status (1)

Country Link
WO (1) WO2012153348A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6502510B2 (en) * 2015-01-30 2019-04-17 ダウ グローバル テクノロジーズ エルエルシー Process for producing brominated and halo-hydrated polymers
HU231079B1 (en) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Process for the preparation of high-purity prasugrel by the elimination of the bromopentyl impurity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011042918A2 (en) * 2009-10-07 2011-04-14 Msn Laboratories Limited Novel and improved processes for the preparation of prasugrel, its intermediates and pharmaceutically acceptable salts
CN102190569A (en) * 2010-03-12 2011-09-21 浙江海翔药业股份有限公司 Method for preparing Prasugrel intermediate alpha-cyclopropylcarbonyl-2-fluorobenzyl bromide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011042918A2 (en) * 2009-10-07 2011-04-14 Msn Laboratories Limited Novel and improved processes for the preparation of prasugrel, its intermediates and pharmaceutically acceptable salts
CN102190569A (en) * 2010-03-12 2011-09-21 浙江海翔药业股份有限公司 Method for preparing Prasugrel intermediate alpha-cyclopropylcarbonyl-2-fluorobenzyl bromide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LEI S. ET AL.: "Research of Capability of Tribromide Quaternary Ammonium Salt.", CHEMICAL TECHNOLOGY MARKET., vol. 26, no. 5., 2003, pages 24 - 25 *

Also Published As

Publication number Publication date
WO2012153348A2 (en) 2012-11-15

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