WO2012142487A1 - Organ care solution for ex-vivo machine perfusion of donor lungs - Google Patents
Organ care solution for ex-vivo machine perfusion of donor lungs Download PDFInfo
- Publication number
- WO2012142487A1 WO2012142487A1 PCT/US2012/033626 US2012033626W WO2012142487A1 WO 2012142487 A1 WO2012142487 A1 WO 2012142487A1 US 2012033626 W US2012033626 W US 2012033626W WO 2012142487 A1 WO2012142487 A1 WO 2012142487A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amount
- solution
- lung
- perfusion
- anhydrate
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00969—Surgical instruments, devices or methods, e.g. tourniquets used for transplantation
Abstract
Description
Claims
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12770852.7A EP2704560B1 (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
ES12770852T ES2913104T3 (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
CA2833266A CA2833266C (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
NZ616699A NZ616699A (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
AU2012242578A AU2012242578B2 (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
CN201280025150.7A CN103841824B (en) | 2011-04-14 | 2012-04-13 | Organ care solution for the in vitro machine perfusion of donor lung |
JP2014505362A JP6029650B2 (en) | 2011-04-14 | 2012-04-13 | Organ protection solution for mechanical perfusion in ex-vivo of donor lung |
CN202210007357.7A CN114375945A (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex vivo machine perfusion of donor lungs |
EP22158928.6A EP4032401A1 (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
DK12770852.7T DK2704560T3 (en) | 2011-04-14 | 2012-04-13 | ORGAN TREATMENT SOLUTION FOR EX-VIVO MACHINE PERFUSION OF DONOR LUNGS |
IL228816A IL228816A (en) | 2011-04-14 | 2013-10-10 | Organ care solution for ex-vivo machine perfusion of donor lungs |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161475524P | 2011-04-14 | 2011-04-14 | |
US61/475,524 | 2011-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2012142487A1 true WO2012142487A1 (en) | 2012-10-18 |
Family
ID=47009719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2012/033626 WO2012142487A1 (en) | 2011-04-14 | 2012-04-13 | Organ care solution for ex-vivo machine perfusion of donor lungs |
Country Status (11)
Country | Link |
---|---|
US (3) | US20130011823A1 (en) |
EP (2) | EP4032401A1 (en) |
JP (1) | JP6029650B2 (en) |
CN (4) | CN103841824B (en) |
AU (1) | AU2012242578B2 (en) |
CA (3) | CA3106469A1 (en) |
DK (1) | DK2704560T3 (en) |
ES (1) | ES2913104T3 (en) |
IL (1) | IL228816A (en) |
NZ (1) | NZ616699A (en) |
WO (1) | WO2012142487A1 (en) |
Cited By (11)
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WO2016162536A1 (en) * | 2015-04-08 | 2016-10-13 | University College Dublin, National University Of Ireland, Dublin | A lung perfusion solution, and use thereof for the ex-vivo preservation of a mammalian lung |
JP2017518301A (en) * | 2014-06-02 | 2017-07-06 | トランスメディクス, インク.Transmedics, Inc. | Ex-vivo organ management system |
US10736314B2 (en) | 2004-10-07 | 2020-08-11 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
US10750738B2 (en) | 2008-01-31 | 2020-08-25 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
US11122795B2 (en) | 2015-09-09 | 2021-09-21 | Transmedics, Inc. | Aortic cannula for ex vivo organ care system |
US11191263B2 (en) | 2004-10-07 | 2021-12-07 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
US11844345B2 (en) | 2005-06-28 | 2023-12-19 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
US11849721B2 (en) | 2017-01-17 | 2023-12-26 | Xvivo Perfusion Ab | Methods of preparing pH-stabilized and heat-sterilized organ preservation and/or perfusion solutions |
US11856944B2 (en) | 2011-04-14 | 2024-01-02 | Transmedics, Inc. | Organ care solution for ex-vivo machine perfusion of donor lungs |
US11917991B2 (en) | 2007-03-20 | 2024-03-05 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
US11963526B2 (en) | 2014-12-12 | 2024-04-23 | Transmedics, Inc. | Apparatus and method for organ perfusion |
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US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
US9301519B2 (en) * | 2004-10-07 | 2016-04-05 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
DK3178319T3 (en) * | 2006-04-19 | 2020-02-03 | Transmedics Inc | EX VIVO ORGAN CARE SYSTEMS |
USD738489S1 (en) * | 2013-05-31 | 2015-09-08 | Resmed Limited | Positive airway pressure delivery console |
USD738488S1 (en) * | 2013-05-31 | 2015-09-08 | Resmed Limited | Positive airway pressure delivery console |
WO2015126853A1 (en) * | 2014-02-18 | 2015-08-27 | Baylor College Of Medicine | Negative pressure ex vivo lung ventilation and perfusion system |
USD744108S1 (en) | 2014-02-19 | 2015-11-24 | Resmed Limited | Humidifier reservoir for positive airway pressure delivery console |
USD743556S1 (en) | 2014-02-19 | 2015-11-17 | Resmed Limited | Positive airway pressure delivery console |
USD762843S1 (en) | 2014-03-18 | 2016-08-02 | Resmed Limited | Air delivery tube |
USD760258S1 (en) | 2014-05-30 | 2016-06-28 | Resmed Limited | Display screen with graphical user interface |
USD809124S1 (en) | 2014-09-12 | 2018-01-30 | Resmed Limited | Pressurized air delivery console |
USD798428S1 (en) | 2015-10-07 | 2017-09-26 | Resmed Limited | Positive airway pressure delivery console |
USD805630S1 (en) | 2016-02-02 | 2017-12-19 | Resmed Limited | Air delivery tube |
CN105918308A (en) * | 2016-04-28 | 2016-09-07 | 上海市胸科医院 | Lung perfusion fluid for perfusing transplant donor lung and preparation method for lung perfusion fluid |
CN109688811B (en) | 2016-07-22 | 2022-06-03 | 苏黎世联邦理工学院 | Perfusion circuit assembly for extracorporeal liver perfusion and liver chamber assembly |
CN107047538B (en) * | 2017-03-16 | 2021-04-13 | 苏州大学 | Application of protein kinase A activator in platelet preservation and platelet preservation method |
MX2020001942A (en) * | 2017-08-25 | 2020-03-26 | Csl Behring Llc | Perfusion compositions and methods of using alpha-1 anti-trypsin in ex vivo organ perfusion. |
CN109511649B (en) * | 2018-11-21 | 2021-06-25 | 嘉兴莱普晟医疗科技有限公司 | Normal-temperature mechanical perfusion system capable of expanding liver supply source |
USD921900S1 (en) | 2018-12-19 | 2021-06-08 | ResMed Pty Ltd | Humidification tub |
CN112273373B (en) * | 2020-10-29 | 2022-06-07 | 无锡市人民医院 | Isolated lung mechanical perfusion liquid and preparation method and application thereof |
CA3154179A1 (en) * | 2021-04-07 | 2022-10-07 | Traferox Technologies Inc. | Donor organ preservation using both static cold storage and ex vivo organ perfusion |
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NZ713560A (en) | 2017-03-31 |
IL228816A (en) | 2017-09-28 |
CA3022104A1 (en) | 2012-10-18 |
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EP2704560A4 (en) | 2014-10-22 |
CN106342788B (en) | 2020-03-17 |
CN103841824A (en) | 2014-06-04 |
US20130011823A1 (en) | 2013-01-10 |
NZ728515A (en) | 2018-04-27 |
CN103841824B (en) | 2016-12-14 |
CN114375945A (en) | 2022-04-22 |
NZ740353A (en) | 2019-06-28 |
IL228816A0 (en) | 2013-12-31 |
CN109997836A (en) | 2019-07-12 |
US20240081323A1 (en) | 2024-03-14 |
EP4032401A1 (en) | 2022-07-27 |
ES2913104T3 (en) | 2022-05-31 |
US11856944B2 (en) | 2024-01-02 |
EP2704560B1 (en) | 2022-04-06 |
CA2833266A1 (en) | 2012-10-18 |
CN106342788A (en) | 2017-01-25 |
CA3022104C (en) | 2024-04-09 |
JP6029650B2 (en) | 2016-11-24 |
NZ754645A (en) | 2021-02-26 |
DK2704560T3 (en) | 2022-05-23 |
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