DE10121159B4 - Artificial thorax - Google Patents
Artificial thorax Download PDFInfo
- Publication number
- DE10121159B4 DE10121159B4 DE10121159A DE10121159A DE10121159B4 DE 10121159 B4 DE10121159 B4 DE 10121159B4 DE 10121159 A DE10121159 A DE 10121159A DE 10121159 A DE10121159 A DE 10121159A DE 10121159 B4 DE10121159 B4 DE 10121159B4
- Authority
- DE
- Germany
- Prior art keywords
- shells
- preparation
- passage
- artificial thorax
- artificial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000000038 chest Anatomy 0.000 title claims abstract description 9
- 238000002360 preparation method Methods 0.000 claims abstract description 17
- 210000003437 trachea Anatomy 0.000 claims abstract description 4
- 239000003633 blood substitute Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 1
- 210000004072 lung Anatomy 0.000 description 8
- 238000002595 magnetic resonance imaging Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 238000011161 development Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000003570 air Substances 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
Künstlicher Thorax zur Aufnahme eines tierischen Herz-Lungen-Präparats, gekennzeichnet durch eine Unterschale (10), eine Oberschale (12), einen ersten Durchlaß (14) zum Erzeugen eines Unterdrucks in dem durch die beiden gasdicht miteinander verbindbaren Schalen (10, 12) gebildeten Raum und einen zweiten Durchlaß (16) zum Durchführen eines in die Luftröhre des Präparäts einzuführenden Trachealtubus, eine in dem durch die beiden Schalen (10, 12) gebildeten Raum angeordnete, das Zwerchfell simulierende Blase (18) und einen mit der Blase (18) kommunizierenden dritten Durchlaß (20)Artificial thorax for receiving an animal heart-lung preparation, characterized by a lower shell (10), an upper shell (12), a first passage (14) for generating a negative pressure in the shells (10, 12) which can be connected to one another in a gastight manner. formed space and a second passage (16) for introducing a tracheal tube to be inserted into the trachea of the preparation, one arranged in the space formed by the two shells (10, 12), the diaphragm simulating bladder (18) and one with the bladder (18 ) communicating third passage (20)
Description
Die Erfindung betrifft einen künstlichen Thorax zur Aufnahme eines tierischen Herz-Lungen-Präparats.The invention relates to an artificial Thorax for receiving an animal heart-lung preparation.
Röntgendiagnostische Verfahren und Magnetresonanztomographie (MRT) unterliegen der ständigen Weiterentwicklung. Besondere Vorteile der MRT sind hervorragender Weichteilkontrast und hohe Detailauflösung. Die Darstellung der Lunge mittels MRT stellt jedoch eine besondere Herausfor derung dar. Problematisch sind die geringe Dichte des Gewebes mit primär geringer Signalstärke und ein schneller Signalzerfall aufgrund von Suszeptibilitätsartefakten. Die bisher bekannten Untersuchungsmethoden der Lunge mittels der MRT haben weitgehend experimentellen Charakter und konnten keinen breiten Eingang in die Routinediagnostik finden. Für die Weiterentwicklung von Untersuchungssequenzen muß die Sensitivität für pathologische Veränderungen im Lungenparenchym ermittelt werden.Diagnostic X-ray Procedures and magnetic resonance imaging (MRI) are subject to constant further development. Special advantages of MRI are excellent soft tissue contrast and high detail resolution. However, MRI imaging is a special one The low density of the fabric is problematic with primary low signal strength and rapid signal decay due to susceptibility artifacts. The previously known examination methods of the lungs by means of MRIs are largely experimental and could not find broad entry into routine diagnostics. For further development of investigation sequences must sensitivity for pathological changes can be determined in the lung parenchyma.
Ein experimentelles Arbeiten an einem tierischen Herz-Lungen-Präparat wird dadurch behindert, daß die Lunge. nach der Schlachtung kollabiert.An experimental work on one animal heart-lung preparation hindered by the fact that Lung. collapsed after slaughter.
Aus der
Der Erfindung liegt die Aufgabe zugrunde, eine Vorrichtung zu schaffen, die es ermöglicht, tierische Herz-Lungen-Präparate für experimentelle Zwecke möglichst realitätsnah einsetzbar zu machen.The invention has for its object a To create a device that enables animal heart-lung preparations for experimental purposes preferably realistically to make it usable.
Erfindungsgemäß wird diese Aufgabe gelöst durch die im kennzeichnenden Teil des Anspruchs 1 angegebenen Merkmale. Die Unteransprüche geben bevorzugte Ausgestaltungen der Erfindung an.According to the invention, this object is achieved by the features specified in the characterizing part of claim 1. The subclaims give preferred embodiments of the invention.
Die Erfindung wird im folgenden anhand von Zeichnungen erläutert, die ein bevorzugtes Ausführungsbeispiel der Erfindung wiedergeben. Dabei zeigt:The invention is illustrated below explained by drawings, which is a preferred embodiment reproduce the invention. It shows:
Der künstliche Thorax, der zur Aufnahme
eines tierischen, insbesondere eines vom Schwein stammenden Herz-Lungen- Präparats dient,
besteht aus einer Unterschale
Ein zweiter Durchlaß
In der Unterschale
Durch die ersten Durchlässe
Weitere Durchlässe
Die Schalen
Bei der Verwendung wird das tierische
Präparat
in die Unterschale
Nach dem Anlegen einer Unterdruckquelle an
die ersten Durchlässe
Zur Simulation einer Atmung wird
die Blase
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10121159A DE10121159B4 (en) | 2001-04-30 | 2001-04-30 | Artificial thorax |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10121159A DE10121159B4 (en) | 2001-04-30 | 2001-04-30 | Artificial thorax |
Publications (2)
Publication Number | Publication Date |
---|---|
DE10121159A1 DE10121159A1 (en) | 2002-11-21 |
DE10121159B4 true DE10121159B4 (en) | 2004-01-29 |
Family
ID=7683267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10121159A Expired - Fee Related DE10121159B4 (en) | 2001-04-30 | 2001-04-30 | Artificial thorax |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE10121159B4 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8535934B2 (en) | 2006-04-19 | 2013-09-17 | Transmedics, Inc. | Systems and methods for ex vivo organ care |
DE102016225167A1 (en) | 2016-12-15 | 2018-06-21 | Otto-Von-Guericke-Universität Magdeburg | Ex vivo pulmonary circulation and ventilation device and method for training surgical and minimally invasive surgical procedures |
DE102018118379A1 (en) * | 2018-07-30 | 2020-01-30 | Westfälische Wilhelms-Universität Münster | Cardiac phantom suitable for MRI |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
US9301519B2 (en) | 2004-10-07 | 2016-04-05 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
NZ614472A (en) | 2004-10-07 | 2015-03-27 | Transmedics Inc | Systems and methods for ex-vivo organ care |
US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
US9814230B2 (en) | 2008-01-31 | 2017-11-14 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
CA2723706C (en) * | 2008-05-06 | 2020-10-20 | Vivoline Medical Ab | Apparatus for housing an organ during evaluation and preservation |
EP2482646A4 (en) | 2009-09-25 | 2017-07-26 | Vivoline Medical AB | Container and supporting structure for housing an organ |
US20130011823A1 (en) | 2011-04-14 | 2013-01-10 | Hassanein Waleed H | Organ care solution for ex-vivo machine perfusion of donor lungs |
CA3185937A1 (en) | 2014-06-02 | 2015-12-10 | Transmedics, Inc. | Ex vivo organ care system |
BR112017010520B1 (en) | 2014-12-12 | 2022-08-30 | Tevosol, Inc | APPARATUS AND METHOD FOR ORGAN PERFUSION |
CN107949419B (en) | 2015-09-09 | 2021-03-05 | 特兰斯迈迪茨公司 | Aorta cannula for isolated organ care system |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19502691C1 (en) * | 1995-01-28 | 1996-03-07 | Sachs Elektronik Kg Hugo | Lung perfusion and ventilation chamber for small experimental animals |
US6046046A (en) * | 1997-09-23 | 2000-04-04 | Hassanein; Waleed H. | Compositions, methods and devices for maintaining an organ |
-
2001
- 2001-04-30 DE DE10121159A patent/DE10121159B4/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19502691C1 (en) * | 1995-01-28 | 1996-03-07 | Sachs Elektronik Kg Hugo | Lung perfusion and ventilation chamber for small experimental animals |
US6046046A (en) * | 1997-09-23 | 2000-04-04 | Hassanein; Waleed H. | Compositions, methods and devices for maintaining an organ |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8535934B2 (en) | 2006-04-19 | 2013-09-17 | Transmedics, Inc. | Systems and methods for ex vivo organ care |
DE102016225167A1 (en) | 2016-12-15 | 2018-06-21 | Otto-Von-Guericke-Universität Magdeburg | Ex vivo pulmonary circulation and ventilation device and method for training surgical and minimally invasive surgical procedures |
DE102016225167B4 (en) | 2016-12-15 | 2018-10-11 | Otto-Von-Guericke-Universität Magdeburg | Ex vivo pulmonary circulation and ventilation device and method for training surgical and minimally invasive surgical procedures |
DE102018118379A1 (en) * | 2018-07-30 | 2020-01-30 | Westfälische Wilhelms-Universität Münster | Cardiac phantom suitable for MRI |
Also Published As
Publication number | Publication date |
---|---|
DE10121159A1 (en) | 2002-11-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
OP8 | Request for examination as to paragraph 44 patent law | ||
8364 | No opposition during term of opposition | ||
R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |
Effective date: 20131101 |