WO2012127366A1 - Système d'injection et dispositif d'actionnement pour fixation à un stylo injecteur pour former un tel système d'injection - Google Patents

Système d'injection et dispositif d'actionnement pour fixation à un stylo injecteur pour former un tel système d'injection Download PDF

Info

Publication number
WO2012127366A1
WO2012127366A1 PCT/IB2012/051210 IB2012051210W WO2012127366A1 WO 2012127366 A1 WO2012127366 A1 WO 2012127366A1 IB 2012051210 W IB2012051210 W IB 2012051210W WO 2012127366 A1 WO2012127366 A1 WO 2012127366A1
Authority
WO
WIPO (PCT)
Prior art keywords
shell
injection system
lever
holding member
actuating device
Prior art date
Application number
PCT/IB2012/051210
Other languages
English (en)
Inventor
Helen Marie MOORE
Original Assignee
Pfizer Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Limited filed Critical Pfizer Limited
Publication of WO2012127366A1 publication Critical patent/WO2012127366A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31586—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/586—Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users

Definitions

  • Injection system and actuating device for attachment to a pen-injector to form such injection system
  • the invention relates to an injection system and to an actuating device for attachment to a pen-injector to form such an injection system.
  • the invention relates to an injection system comprising a pen-injector used to ease the injection of a product, especially a therapeutic or pharmaceutical product, to a patient by the patient.
  • the invention relates to an injection system comprising a pen-injector including:
  • a shell for accommodating a container of a product to be injected and an injection mechanism for expelling a dose of the product from said container upon actuation, said shell having an elongated outer surface extending along a central axis, and having proximal and distal sections, and
  • an actuator for actuating said injection mechanism said actuator being slidably mounted along the central axis on the proximal section of the shell.
  • the invention aims to solve the above mentioned problem.
  • the invention provides for an injection system of the aforementioned type further comprising an actuating device comprising:
  • a lever pivotally connected to the proximal section of the shell by a pivot connection having a pivot axis substantially perpendicular to the central axis of the shell, said lever being adapted to cover and press at least a part of the actuator when actuated by a patient,
  • a holding member radially protruding from the outer surface of the shell at an axial distance from the pivot connection, said holding member being adapted to bear on a patient's finger while enabling the patient to actuate the lever with another finger.
  • the pen-injector can be held in the opened hand of the patient, especially in the palm of the patient, with the holding member bearing on one finger and the lever moved by another finger, especially the thumb, with a limited amount of force.
  • the actuating device eases the holding and the actuation of the pen-injector, even by a patient having a limited dexterity, thereby enabling the patient to inject himself the product to be injected.
  • the holding member may comprise a curved tab having a concavity turned towards a distal direction.
  • the lever may be movable in a radial plane containing the central axis and a direction in which the holding member extends, the pivot connection and the holding member lying on a same side of the central axis in said radial plane.
  • the lever may be directly pivotally mounted on the proximal section of the shell and the holding member may be made integral with the shell.
  • the actuating device may further comprise a body extending along a longitudinal axis and being coaxially attached to the outer surface of the shell, the lever being pivotally mounted on a proximal portion of the body.
  • the body of the actuating device may be releasably attached to the shell.
  • the body may be provided with releasable attaching means engaging the proximal section of the shell.
  • releasable attaching means comprises a collar coaxially snap-fitted onto the outer surface of shell of the pen-injector.
  • the holding member may be made integral with the body of the actuating device.
  • the injection system as previously defined may further comprise a container of a product to be injected and an injection mechanism accommodated in said shell, said container containing a medicament for the treatment of arthritis.
  • the invention proposes an actuating device for attachment to a pen-injector having a shell with an elongated outer surface extending along a central axis, and an actuator slidably mounted along the central axis on a proximal section of the shell, said actuating device comprising:
  • a lever pivotally mounted on a proximal portion of the body by a pivot connection having a pivot axis substantially perpendicular to the longitudinal axis, said lever being adapted to cover and press at least a part of the actuator of the pen-injector when actuated by a patient,
  • a holding member radially protruding from the body at an axial distance from the pivot connection, said holding member being adapted to bear on a patient's finger while enabling the patient to actuate the lever with another finger.
  • the holding member may comprise a curved tab having a concavity turned towards a distal direction.
  • the body may be provided with releasable attaching means adapted to engage the proximal section the shell of the pen-injector.
  • the releasable attaching means comprises a collar adapted to coaxially snap-fit onto the outer surface of the shell of the pen-injector.
  • the holding member may be made integral with the body.
  • FIG. 1 is a perspective view of an injection system according to a first embodiment of the invention, the injection system comprising a pen-injector and an actuating device, the actuating device comprising a lever and a holding member attached to a body fitted onto the pen-injector,
  • Figure 2 is a view in longitudinal cross section of the injection system of Figure 1 ,
  • FIG. 3 is a lateral view of the actuating device of the injection system of Figure 1
  • - Figure 4 is an exploded view of the injection system of Figure 1
  • FIG. 5 is a view in longitudinal cross section of an injection system according to a second embodiment of the invention, the lever of the actuating device being directly attached to the pen-injector and the holding member of the actuating device being integral with the pen- injector,
  • FIGS. 6a and 6b are perspective views of a use of the injection system of Figure 1 , illustrating the injection system held by the hand of a patient, the holding member bearing on the patient's middle finger while enabling the patient to actuate the lever with the thumb.
  • Figures 1 to 4 represent a first embodiment of an injection system 1 used, in particular by a patient himself, to inject a dose of a therapeutic or pharmaceutical product, such as a medicine or a drug.
  • a therapeutic or pharmaceutical product such as a medicine or a drug.
  • the injection system 1 comprises a pen-injector 2 of a general cylindrical shape around a central axis A.
  • the pen-injector 2 comprises a cylindrical hollow shell 3 of circular cross-section.
  • the shell 3 extends along the central axis A between opposite proximal 4 and distal 5 sections and presents an elongated inner surface 6 defining a housing 7 and an elongated outer surface 8 opposite to the inner surface 6.
  • the housing 7 is adapted to accommodate a container (not shown) of the product to be injected and an injection mechanism (also not shown) for expelling the dose of product from the container.
  • the container and the injection mechanism together form a syringe received and held within the housing 7 so that at least a part of a needle of the syringe extends out of the distal section 5 of the shell 3.
  • the injection mechanism may comprise a piston slidably mounted along the central axis on the shell 3 and a needle secured to the shell 3 so that at least a part of it extends out of the distal section 5 of the shell 3.
  • the container can be placed within the housing 7 to cooperate with the injection mechanism mounted on the shell 3.
  • a cylindrical actuator 10 of circular cross-section is mounted on the proximal section 4 of the shell 3.
  • the actuator 10 extends along the central axis A between a lower surface 1 1 arranged within the housing 7 and an upper surface 12 which protrudes from the proximal section 4 of the shell 3.
  • the actuator 10 is mounted so as to slide along a stroke extending along the central axis A.
  • the actuator 10 is lowered through a pressure exerted on its upper surface 12. The actuator 10 may then be resiliency biased or otherwise moved to an upstanding position for a subsequent actuation.
  • the invention disclosed in relation to a pen-injector 2 having a general cylindrical shape of circular cross-section is not limited thereto and could have any other cross-section, such as elliptic or polygonal, and more generally any other shape.
  • the injection system comprises an actuating device 15.
  • the actuating device 15 is formed as a separate component and comprises a body 16 mounted on the shell 3 of the pen-injector 2.
  • the body 16 comprises a collar 17 around a longitudinal axis B.
  • the collar 17 is cylindrical, and especially annular, around the longitudinal axis B.
  • the collar 17 has an outer surface 19 and an inner surface 18 defining an opening adapted to receive the pen-injector 2 for fitting the collar 17 onto the outer surface 8 of the shell 3.
  • the inner surface 18 of the collar 17 and the outer surface 8 of the shell 3 may have complementary retention members, in the form, in the represented embodiment, of an annular bead 20 on the inner surface 18 of the collar 17 and an annular groove 21 on the outer surface 8 of the shell 3.
  • the shape and the dimensions of the collar 17, and especially of the inner surface 18, could be different to adapt to the shape and the dimensions of the outer surface 8 of the shell 3 of the pen-injector 2.
  • the represented cylindrical collar 17 is continue to form an attachment element fitted along the central axis A of the pen-injector 2
  • the cylindrical collar 17 could be discontinue, i.e. opened in a direction perpendicular to the longitudinal axis B, to form an attachment element either fitted along the central axis A or clamped in a direction perpendicular to the central axis A.
  • the body 16 also comprises a wall 25 arranged at a distance, measured transversally with respect to the longitudinal axis B, from the longitudinal axis B.
  • the wall 25 is integral with the collar 17 and extends substantially along the longitudinal axis B from the collar 17 to a proximal portion 26.
  • the wall 25 is inclined with respect to the longitudinal axis B, moving away from the longitudinal axis B. It should be noted that, in other embodiments, the wall 25 could be straight along the longitudinal axis B or the wall 25 could be a part of the collar 17 on which the proximal portion 26 is formed.
  • the proximal portion 26 of the wall 25 supports a lever 30.
  • the lever 30 has a connecting end 31 and a free end 32 and presents a length between these connecting 31 and free 32 ends.
  • the length of the lever 30 is greater than a transverse dimension of the collar 17, measured perpendicularly to the longitudinal axis B, corresponding, in the illustrated embodiment, to a diameter of the outer surface 19 of the collar 17.
  • the lever 30, thereby, extends transversally with respect to the longitudinal axis B, toward the longitudinal axis B, and crosses the longitudinal axis B.
  • the length of the lever 30 is, therefore, greater than a transverse dimension of the pen-injector 2, measured perpendicularly to the central axis A of the pen-injector 2, corresponding, in the illustrated embodiment, to a diameter of the outer surface 8 of the shell 3.
  • the lever 30 is curved between the connecting end 31 and the free end 32 and presents a concavity directed towards the collar 17 in the actionable position of Figure 3.
  • the lever 30 presents a lower surface 33, facing the opening of the collar 17 in the actionable position, and an upper surface 34 opposite to the lower surface 33.
  • the lower surface 33 is provided with a protrusion 35, in the form of a central knob 36.
  • the upper surface 34 is provided with a grip portion 37, in the form of transverse ribs 38, arranged close to the free end 32 of the lever 30.
  • the lever 30 is pivotally mounted on the proximal portion 26 of the wall 25 by a pivot connection.
  • the pivot connection is a hinge 40 which includes a socket 41 extending along a pivot axis P substantially perpendicular to the longitudinal axis B, and a pin 42 extending within the socket 41 .
  • the socket 41 is attached to the proximal portion 26 of the wall 25 and the pin 42 is attached to the connecting end 31 of the lever 30.
  • the attachments of the socket 41 and the pin 42 could be inverted.
  • the lever 30 could be connected to the proximal portion 26 of the body 16 by a pivot connection formed of a resiliency deformable portion integral with both the lever 30 and the wall 25.
  • the body 16 further comprises an arm 43 extending parallel to the longitudinal axis B from the collar 17 opposite to the wall 25.
  • the arm 43 is intended to be in contact with the shell 3 of the pen-injector 2 and is, therefore, conformed to match the outer surface 8 of the shell 3.
  • the arm 43 has an inner surface 44 curved around the longitudinal axis B and an outer surface 45 opposite to the inner surface 44.
  • a holding member 50 integral with the arm 43 of the body 16 is provided to enable the patient to hold the pen-injector 2 when the actuating device 15 is mounted on the pen-injector 2.
  • the holding member 50 is arranged at an axial distance, along the longitudinal axis B, from the pivot connection 40 and protrudes from the outer surface 45 of the arm 43.
  • the holding member 50 extends in a radial direction with respect to the longitudinal axis B, opposite to the longitudinal axis B.
  • the holding member 50 has an end attached to the arm 43 and arranged substantially in alignment with the connecting end 31 of the lever 30 and the pivot connection 40 along the longitudinal axis B.
  • the lever 30 and the holding member 50 extend in a same radial plane containing the longitudinal axis B and the radial direction in which the holding member 50 extends, the pivot connection 40 and the holding member 50 being arranged on the same side of the longitudinal axis B in the radial plane.
  • the lever 30 in its actionable position shown of Figure 3 and the holding member 50 extend in opposite directions with respect to the longitudinal axis B. It should be noted, however, that any other suitable relative orientations of the lever 30 and the holding member 50 could be provided, the body 16, and especially the arm 43, being adapted accordingly.
  • the holding member 50 is shaped and arranged to bear on a patient's finger while enabling the patient to actuate the lever 30 with another finger.
  • finger it is meant one of the five digits of a hand, including the thumb.
  • the holding member 50 comprises a curved tab 51 having opposite upper 52 and lower 53 contact surfaces extending substantially transversally with respect to the longitudinal axis B.
  • the tab 51 has a curvature matching substantially that of the fingers of the patient.
  • the curvature of the tab 51 is advantageously a concavity 53A directed opposite to the lever 30 to act as a purchase as the lever 30 is depressed.
  • the invention is not limited to the holding member 50 in the form of the curved tab 51 .
  • Any other suitable shape could be provided for the holding member, for example, the holding member may comprise one or several loops of which the arcuate tab 51 forms a part.
  • the body 16 of the actuating device 15 is coaxially attached to the outer surface 8 of the shell 3 of the pen-injector 2.
  • the collar 17 is snap-fitted onto the shell 3 of the pen-injector 2, the inner surface 19 of the collar 17 being in contact with the outer surface 8 of the shell 3 and the bead 20 of the collar 17 being engaged in the groove 21 of the shell 3.
  • the longitudinal axis B of the body 16 is coaxial to the central axis A of the pen-injector 2 and the proximal portion 26 of the body 16 is arranged at the vicinity of the proximal section 4 of the shell 3.
  • the collar 17 is snap-fitted to the shell 3 on its proximal section 4 whereas it could alternatively be fitted on any other part of the shell 3, the dimension of the wall 25 being adapted accordingly to have the proximal portion 26 arranged at the vicinity of the proximal section 4 of the shell 3.
  • the lever 30 is pivotally mounted on the proximal section 4 of the shell 3, through the collar 17, the wall 25 and the pivot connection 40.
  • the pivot connection 40 and the holding member 50 lie on the same side of the radial plane in which the holding member 50 and the lever 30 extend.
  • the radial plane contains the central axis A and the pivot axis P is perpendicular to the central axis A of the pen-injector 2.
  • the lever 30 In the actionable position, the lever 30 extends transversally with respect to the central axis A, toward the central axis A.
  • the connecting end 31 of the lever 30 is attached on a first side of the actuator 10 and the free end 32 of the lever 30 protrudes transversally with respect to a second side of the actuator 10, opposite to the first side in relation to the central axis A.
  • the lever 30 covers the actuator 10 of the pen-injector 2, with the knob 36 in contact with the upper surface 12 of the actuator 10 and the free end 32 arranged at a distance, measured transversally with respect to the central axis A, from the actuator 10.
  • the lever 30 is moveable in the radial plane to actuate the actuator 10.
  • the inner surface 44 of the arm 43 of the actuating device 15 is in contact with the outer surface 8 of the shell 3.
  • the upper 52 and lower 53 contact surfaces of the curved tab 51 extend substantially transversally with respect to the central axis A of the pen-injector 2, with the concavity turned towards a distal direction, i.e. towards the distal section 5 of the shell 3.
  • the injection system 1 can be held by the patient with his opened hand 60.
  • the curved tab 51 of the actuating device 15 bears on the middle finger 61 , and the lever 30 is pressed toward the proximal section 4 of the shell 3 by another finger of the patient, for example the thumb 62, placed on the grip portion 37 of the lever 30. Thanks to these provisions, the patient does not need to firmly grasp the pen-injector 2 by closing the hand 60.
  • the free end 31 of the lever 30 arranged at a distance from the actuator 10 reduces the force to be exerted to move the actuator 10.
  • the invention has been disclosed in relation to an actuating device 15 snap- fitted onto the pen-injector 2, in other embodiments, the actuating device 15 could be attached , permanently or removably, to the pen-injector 2 in any other appropriate manner, for example by clamping, gluing or welding the body 16 to the outer surface 8 of the shell 3. Besides, the holding member 50 could be separate from the body 16 and mounted on the shell 3 apart of the body 16 on which the lever 30 is articulated.
  • Figure 5 represents a second embodiment of an injection system 1 '.
  • the pen-injector 2' is similar to that of the first embodiment and will not be disclosed in details.
  • the elements of the second embodiment similar to that of the first embodiment are referenced with the same reference numbers with the mark ""' added. Their description will not be repeated and reference is made to the description already made for more details.
  • the injection system 1 ' according to the second embodiment differs mainly with respect to that of the first embodiment in the realisation of the actuating device 15' formed as an integrated component.
  • the lever 30' is directly mounted on the proximal section 4' of the shell 3' of the pen-injector 2' and the holding member 50', also represented in the form of an arcuate tab 51 ', is integral with the shell 3' of the pen-injector 2'.
  • the connecting end 31 ' of the lever 30' is pivotally mounted on a wall 25' arranged on the proximal section 4' of the shell 3' and extending to a proximal portion 26' of the shell 3'.
  • the actuating device 15' comprises a hinge 40', as pivot connection, which includes a socket 41 ' extending along the pivot axis P' and a pin 42' extending within the socket 41 '.
  • the socket 41 ' is mounted on the proximal portion 26' of the shell 3' and the pin 42' is mounted on the connecting end 31 ' of the lever 30'.
  • the attachments of the socket 41 ' and the pin 42' could be inverted.
  • the tab 51 ' protrudes from the outer surface 8' of the shell 3' with the upper 52' and lower 53' contact surfaces extending transversally with respect to the central axis A'.
  • the injection system 1 ' of the second embodiment functions in a similar manner as that of the injection system 1 of the first embodiment.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un système d'injection (1) comprenant un stylo injecteur (2) comprenant : - une coque (3) ayant une surface extérieure allongée et des sections proximale et distale, et - un actionneur (10) monté de façon coulissante sur la section proximale de la coque (3), ledit système d'injection comprenant en outre un dispositif d'actionnement (15) comprenant : - un levier (30) raccordé de façon pivotante à la section proximale de la coque (3) et adapté pour couvrir et presser au moins une partie de l'actionneur (10) lorsqu'il est actionné par un patient, - un composant de support (50) faisant radialement saillie depuis la surface extérieure de la coque (3) et étant adapté pour tenir sur le doigt d'un patient (61) tout en permettant au patient d'actionner le levier (30) avec un autre doigt (62).
PCT/IB2012/051210 2011-03-23 2012-03-14 Système d'injection et dispositif d'actionnement pour fixation à un stylo injecteur pour former un tel système d'injection WO2012127366A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161466633P 2011-03-23 2011-03-23
US61/466,633 2011-03-23

Publications (1)

Publication Number Publication Date
WO2012127366A1 true WO2012127366A1 (fr) 2012-09-27

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PCT/IB2012/051210 WO2012127366A1 (fr) 2011-03-23 2012-03-14 Système d'injection et dispositif d'actionnement pour fixation à un stylo injecteur pour former un tel système d'injection

Country Status (4)

Country Link
JP (1) JP2012200601A (fr)
AR (1) AR085465A1 (fr)
TW (1) TW201304831A (fr)
WO (1) WO2012127366A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140228756A1 (en) * 2011-08-29 2014-08-14 IN.TOOL ApS Instrument for assisting a user during injection, a method of use and a system comprising said instrument
WO2015004351A1 (fr) 2013-07-12 2015-01-15 Genia Dispositif d'injection de fluide aux animaux, notamment par voie intranasale
CN104755119A (zh) * 2012-10-19 2015-07-01 安进公司 改进的自动注射器
WO2017176476A1 (fr) * 2016-04-08 2017-10-12 Allergan, Inc. Dispositif d'aspiration et d'injection

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3127570B1 (fr) * 2014-03-31 2020-05-06 Terumo Kabushiki Kaisha Seringue
KR200493124Y1 (ko) * 2018-06-18 2021-02-04 양성보 주사 보조 장치

Citations (1)

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Publication number Priority date Publication date Assignee Title
US5135507A (en) * 1990-05-10 1992-08-04 Habley Medical Technology Corporation One-piece syringe

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US5135507A (en) * 1990-05-10 1992-08-04 Habley Medical Technology Corporation One-piece syringe

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140228756A1 (en) * 2011-08-29 2014-08-14 IN.TOOL ApS Instrument for assisting a user during injection, a method of use and a system comprising said instrument
CN111298241A (zh) * 2012-10-19 2020-06-19 安进公司 改进的自动注射器
CN104755119A (zh) * 2012-10-19 2015-07-01 安进公司 改进的自动注射器
KR20150101987A (ko) * 2012-10-19 2015-09-04 암젠 인크 개선된 자기 주사기
EP2908893A4 (fr) * 2012-10-19 2016-06-15 Amgen Inc Auto-injecteur amélioré
KR102279994B1 (ko) * 2012-10-19 2021-07-20 암젠 인크 개선된 자기 주사기
US10398854B2 (en) 2012-10-19 2019-09-03 Amgen Inc. Autoinjector
WO2015004351A1 (fr) 2013-07-12 2015-01-15 Genia Dispositif d'injection de fluide aux animaux, notamment par voie intranasale
FR3008307A1 (fr) * 2013-07-12 2015-01-16 Genia Dispositif d'injection de fluide aux animaux, notamment par voie intranasale
WO2017176476A1 (fr) * 2016-04-08 2017-10-12 Allergan, Inc. Dispositif d'aspiration et d'injection
US10596321B2 (en) 2016-04-08 2020-03-24 Allergan, Inc. Aspiration and injection device
CN109310827A (zh) * 2016-04-08 2019-02-05 阿勒根公司 抽吸和注射装置
US11890457B2 (en) 2016-04-08 2024-02-06 Allergan, Inc. Aspiration and injection device

Also Published As

Publication number Publication date
AR085465A1 (es) 2013-10-02
JP2012200601A (ja) 2012-10-22
TW201304831A (zh) 2013-02-01

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