WO2012120544A3 - Process for the preparation of n- [2-n-butyl-3-[4-[3-[di-n-butylamino] propoxy] benzoyl] benzofuran-5-yl]methanesul fonamide hydrochloride - Google Patents

Process for the preparation of n- [2-n-butyl-3-[4-[3-[di-n-butylamino] propoxy] benzoyl] benzofuran-5-yl]methanesul fonamide hydrochloride Download PDF

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Publication number
WO2012120544A3
WO2012120544A3 PCT/IN2012/000167 IN2012000167W WO2012120544A3 WO 2012120544 A3 WO2012120544 A3 WO 2012120544A3 IN 2012000167 W IN2012000167 W IN 2012000167W WO 2012120544 A3 WO2012120544 A3 WO 2012120544A3
Authority
WO
WIPO (PCT)
Prior art keywords
butylamino
benzofuran
propoxy
benzoyl
butyl
Prior art date
Application number
PCT/IN2012/000167
Other languages
French (fr)
Other versions
WO2012120544A2 (en
Inventor
Rajesh Lalmani GIRI
Vishal Diliprao MOHITE
Sudhakar Kambhampati
Trinadha Rao Chitturi
Rajamannar Thennati
Original Assignee
Sun Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Industries Ltd. filed Critical Sun Pharmaceutical Industries Ltd.
Publication of WO2012120544A2 publication Critical patent/WO2012120544A2/en
Publication of WO2012120544A3 publication Critical patent/WO2012120544A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

The present invention provides a process for preparing compound of formula (I),
PCT/IN2012/000167 2011-03-10 2012-03-12 PROCESS FOR N-[2-n-BUTYL-3-[4-[3-(DI-n-BUTYLAMINO) PROPOXY]ENZOYL]BENZOFURAN-5-YL]METHANESULFONAMIDE HYDROCHLORIDE WO2012120544A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN667MU2011 2011-03-10
IN667/MUM/2011 2011-03-10

Publications (2)

Publication Number Publication Date
WO2012120544A2 WO2012120544A2 (en) 2012-09-13
WO2012120544A3 true WO2012120544A3 (en) 2012-11-01

Family

ID=46579282

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000167 WO2012120544A2 (en) 2011-03-10 2012-03-12 PROCESS FOR N-[2-n-BUTYL-3-[4-[3-(DI-n-BUTYLAMINO) PROPOXY]ENZOYL]BENZOFURAN-5-YL]METHANESULFONAMIDE HYDROCHLORIDE

Country Status (1)

Country Link
WO (1) WO2012120544A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102180848A (en) * 2010-12-31 2011-09-14 江苏万全特创医药生物技术有限公司 Preparation method for novel antiarrhythmic medicament of dronedarone
WO2011153923A1 (en) * 2010-06-09 2011-12-15 江苏恒瑞医药股份有限公司 Preparation process of dronedarone and its salts
WO2012004658A2 (en) * 2010-07-09 2012-01-12 Frichem Private Limited Process for preparation of n-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide, acid addition salts and product thereof
EP2428511A1 (en) * 2010-09-09 2012-03-14 USV Limited Synthesis of dronedarone and salts thereof
WO2012032545A1 (en) * 2010-09-08 2012-03-15 Cadila Healthcare Limited Processes for preparing dronedarone and its intermediates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (en) 1990-08-06 1992-11-27 Sanofi Sa AMINO-BENZOFURAN, BENZOTHIOPHENE OR INDOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE COMPOSITIONS CONTAINING THEM.
DE60007164T2 (en) 1999-10-21 2004-09-16 Rhodia Chimie METHOD FOR PRODUCING BENZOFURANES OR BENZOTHIOPHENES
FR2800067B1 (en) 1999-10-21 2004-12-17 Rhodia Chimie Sa INTERMEDIATES FOR THE MANUFACTURE OF A BENZOFURANE OR NITROGEN BENZOTHIOPHENE DERIVATIVE IN POSITION 5 AND THEIR USES
FR2817864B1 (en) 2000-12-11 2003-02-21 Sanofi Synthelabo METHANESULFONAMIDO-BENZOFURANE DERIVATIVE, ITS PREPARATION METHOD AND ITS USE AS A SYNTHESIS INTERMEDIATE
FR2817865B1 (en) 2000-12-11 2005-02-18 Sanofi Synthelabo AMINOALKOXYBENZOYLE DERIVATIVE IN SALT FORM, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS SYNTHESIS INTERMEDIATE
IL146389A0 (en) 2001-11-08 2002-07-25 Isp Finetech Ltd Process for the preparation of dronedarone
DE10237819A1 (en) 2002-08-19 2004-03-04 Bayer Ag 5-Nitrobenzofurane
GB0611210D0 (en) 2006-06-07 2006-07-19 Cambrex Karlskoga Ab Process
GB0719180D0 (en) 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
FR2959132A1 (en) 2010-04-22 2011-10-28 Sanofi Aventis METHODS FOR RISK EVALUATION AND REDUCTION

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011153923A1 (en) * 2010-06-09 2011-12-15 江苏恒瑞医药股份有限公司 Preparation process of dronedarone and its salts
WO2012004658A2 (en) * 2010-07-09 2012-01-12 Frichem Private Limited Process for preparation of n-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide, acid addition salts and product thereof
WO2012032545A1 (en) * 2010-09-08 2012-03-15 Cadila Healthcare Limited Processes for preparing dronedarone and its intermediates
EP2428511A1 (en) * 2010-09-09 2012-03-14 USV Limited Synthesis of dronedarone and salts thereof
CN102180848A (en) * 2010-12-31 2011-09-14 江苏万全特创医药生物技术有限公司 Preparation method for novel antiarrhythmic medicament of dronedarone

Also Published As

Publication number Publication date
WO2012120544A2 (en) 2012-09-13

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