SG11201400120UA - Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide - Google Patents

Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide

Info

Publication number
SG11201400120UA
SG11201400120UA SG11201400120UA SG11201400120UA SG11201400120UA SG 11201400120U A SG11201400120U A SG 11201400120UA SG 11201400120U A SG11201400120U A SG 11201400120UA SG 11201400120U A SG11201400120U A SG 11201400120UA SG 11201400120U A SG11201400120U A SG 11201400120UA
Authority
SG
Singapore
Prior art keywords
ylcarbonylamino
dimethylaminomethyl
benzofuran
benzamide
ethoxy
Prior art date
Application number
SG11201400120UA
Inventor
Ioana Kloos
Renata Robert
Anne Jacquet-Bescond
Stéphane Depil
Marylore Chenel
Sylvain Fouliard
Sriram Balasubramanian
Original Assignee
Servier Lab
Pharmacyclics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab, Pharmacyclics Inc filed Critical Servier Lab
Publication of SG11201400120UA publication Critical patent/SG11201400120UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
SG11201400120UA 2011-09-08 2012-09-07 Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide SG11201400120UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161573585P 2011-09-08 2011-09-08
FR1102727 2011-09-08
PCT/FR2012/052004 WO2013034863A1 (en) 2011-09-08 2012-09-07 Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide

Publications (1)

Publication Number Publication Date
SG11201400120UA true SG11201400120UA (en) 2014-09-26

Family

ID=47830027

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201400120UA SG11201400120UA (en) 2011-09-08 2012-09-07 Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide
SG10201505619QA SG10201505619QA (en) 2011-09-08 2012-09-07 Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201505619QA SG10201505619QA (en) 2011-09-08 2012-09-07 Scheme for administering n-hydroxy-4-{2-[3-(n,n-dimethylaminomethyl)­benzofuran-2-ylcarbonylamino]ethoxy}benzamide

Country Status (17)

Country Link
US (2) US8883199B2 (en)
EP (1) EP2753322B1 (en)
JP (1) JP6014142B2 (en)
KR (1) KR20140073521A (en)
CN (1) CN103889409A (en)
AR (1) AR087803A1 (en)
AU (2) AU2012306122A1 (en)
CA (1) CA2847011A1 (en)
HK (1) HK1201150A1 (en)
MX (1) MX2014002663A (en)
RU (1) RU2600793C2 (en)
SG (2) SG11201400120UA (en)
TW (1) TWI544920B (en)
UA (1) UA113634C2 (en)
UY (1) UY34295A (en)
WO (1) WO2013034863A1 (en)
ZA (1) ZA201401710B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4243628B2 (en) 2003-04-07 2009-03-25 ファーマサイクリックス,インコーポレイティド Hydroxamate as a therapeutic agent
PL2099442T3 (en) * 2006-12-26 2015-04-30 Pharmacyclics Inc Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
NZ579048A (en) * 2007-01-30 2012-05-25 Pharmacyclics Inc Methods for determining cancer resistance to histone deacetylase inhibitors
US8603521B2 (en) 2009-04-17 2013-12-10 Pharmacyclics, Inc. Formulations of histone deacetylase inhibitor and uses thereof
AU2011376953B2 (en) 2011-09-13 2017-08-24 Pharmacyclics Llc Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof
EP3027192A4 (en) 2013-08-02 2017-03-22 Pharmacyclics, LLC Methods for the treatment of solid tumors
KR101684854B1 (en) * 2016-06-13 2016-12-09 아이오틴 주식회사 Smart medicine case using guardian message notification function, and medication time notification system comprising the same
CN114146181B (en) * 2021-10-29 2022-09-09 徐诺药业(南京)有限公司 Combination containing Pan-HDAC and immune checkpoint inhibitor and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1489078B1 (en) * 2002-03-28 2010-01-06 Mitsubishi Tanabe Pharma Corporation Benzofuran derivative
CA2482508A1 (en) * 2002-04-15 2003-10-30 Sloan-Kettering Institute For Cancer Research Combination therapy for the treatment of cancer
JP4243628B2 (en) * 2003-04-07 2009-03-25 ファーマサイクリックス,インコーポレイティド Hydroxamate as a therapeutic agent
EP1874324A1 (en) * 2005-04-21 2008-01-09 Alza Corporation Method for treating advanced ovarian cancer with doxorubicin entrapped in liposomes

Also Published As

Publication number Publication date
TW201313228A (en) 2013-04-01
UY34295A (en) 2013-04-30
RU2600793C2 (en) 2016-10-27
EP2753322A1 (en) 2014-07-16
US20130064880A1 (en) 2013-03-14
AU2012306122A1 (en) 2014-03-13
UA113634C2 (en) 2017-02-27
KR20140073521A (en) 2014-06-16
SG10201505619QA (en) 2015-08-28
CN103889409A (en) 2014-06-25
MX2014002663A (en) 2014-08-29
HK1201150A1 (en) 2015-08-28
AU2016202594B2 (en) 2017-09-14
CA2847011A1 (en) 2013-03-14
WO2013034863A1 (en) 2013-03-14
EP2753322B1 (en) 2016-08-03
JP2014526457A (en) 2014-10-06
US20150024040A1 (en) 2015-01-22
RU2014113399A (en) 2015-10-20
JP6014142B2 (en) 2016-10-25
NZ622112A (en) 2016-07-29
ZA201401710B (en) 2015-01-28
US8883199B2 (en) 2014-11-11
AU2016202594A1 (en) 2016-05-19
AR087803A1 (en) 2014-04-16
TWI544920B (en) 2016-08-11

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