WO2012118592A1 - Device and method for administering oral disinfecting solutions and other medicaments - Google Patents
Device and method for administering oral disinfecting solutions and other medicaments Download PDFInfo
- Publication number
- WO2012118592A1 WO2012118592A1 PCT/US2012/023462 US2012023462W WO2012118592A1 WO 2012118592 A1 WO2012118592 A1 WO 2012118592A1 US 2012023462 W US2012023462 W US 2012023462W WO 2012118592 A1 WO2012118592 A1 WO 2012118592A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- purge
- water reservoir
- animal
- administration
- molecular iodine
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 30
- 239000003814 drug Substances 0.000 title abstract description 63
- 230000000249 desinfective effect Effects 0.000 title description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 63
- 241001465754 Metazoa Species 0.000 claims abstract description 54
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims abstract description 36
- 238000004891 communication Methods 0.000 claims abstract description 35
- 239000012530 fluid Substances 0.000 claims abstract description 28
- 230000004913 activation Effects 0.000 claims abstract description 20
- 239000007864 aqueous solution Substances 0.000 claims abstract description 7
- 238000010926 purge Methods 0.000 claims description 52
- 210000000214 mouth Anatomy 0.000 claims description 11
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 8
- 238000001179 sorption measurement Methods 0.000 claims description 7
- 239000002699 waste material Substances 0.000 claims description 6
- 238000012545 processing Methods 0.000 claims description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 230000035622 drinking Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 abstract description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 12
- 206010006326 Breath odour Diseases 0.000 abstract 1
- 239000003651 drinking water Substances 0.000 abstract 1
- 235000020188 drinking water Nutrition 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 19
- 239000000243 solution Substances 0.000 description 11
- 230000006870 function Effects 0.000 description 9
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 7
- 229910052740 iodine Inorganic materials 0.000 description 6
- 239000011630 iodine Substances 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 241000282472 Canis lupus familiaris Species 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229920006395 saturated elastomer Polymers 0.000 description 3
- 210000001685 thyroid gland Anatomy 0.000 description 3
- 241000282412 Homo Species 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 235000015872 dietary supplement Nutrition 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 208000028169 periodontal disease Diseases 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 241000282326 Felis catus Species 0.000 description 1
- 208000025157 Oral disease Diseases 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- -1 pharmaceutical Substances 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K7/00—Watering equipment for stock or game
- A01K7/02—Automatic devices ; Medication dispensers
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- A—HUMAN NECESSITIES
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- A01K7/00—Watering equipment for stock or game
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Definitions
- Embodiments of the present invention are directed to devices and methods for administering oral disinfecting solutions and other medicaments.
- Embodiments of the present invention are particularly suited for treating oral disease in animals and humans and feature the use or molecular iodine.
- the term "bad oral breath” is used to mean a condition of an animal or human in which the breath carries a foul odor. This odor is caused by microbes in the mouth between the teeth and gum tissue and may take on a "rotten egg” smell due to the production of sulfur containing disease. Infection of the area between the teeth and gums is referred to as periodontal disease.
- Iodine exists in many forms in aqueous solution at room temperature and neutral pH. These forms include ⁇ , I 2 , HOI, H 2 OI + , ⁇ , F/, and I5 " .
- the term "molecular iodine” is used to denote the I 2 form of iodine.
- Embodiments of the present invention feature devices and methods for administering a medicament to an animal or human.
- the medicaments are useful for the treatment of active disease or to prevent the occurrence of disease.
- the term “treat” or “treatment” is used herein to encompass both the treatment of active disease and the prevention of disease.
- One embodiment of the present invention is directed to a device for administering a medicament for the treatment of a disease.
- the device comprises a source of medicament in a fluid, measuring means, an administration switch and a water reservoir means.
- the measuring means is in fluid communication with said source of medicament for measuring an aliquot of medicament corresponding to a dose for the treatment of a disease.
- the measuring means is also in communication with a water reservoir means and releases the aliquot into the water reservoir means upon signal activation.
- the administration switch means is in signal communication with the measuring means and upon activation by a subject, such as a human or animal, produces an activation signal received by the measuring means.
- the water reservoir means is for receiving the aliquot
- the term "medicament” is a drug, pharmaceutical, nutraceutical, vitamin, antimicrobial, dietary supplement, or disinfectant.
- One antimicrobial is molecular iodine.
- Molecular iodine may also be used as a dietary supplement for thyroid function.
- Molecular iodine in an aqueous solution is well suited for the disinfection of the oral cavity.
- One source of medicament comprises a vessel containing molecular iodine in an ethanol solution.
- One embodiment of the present invention features molecular iodine added to the water reservoir means as an absolute alcohol solution saturated with I 2 .
- an effective amount of this solution is formed with 1.0 to 0.001 ml, more preferably, 0.1 to 0.025 ml, to about 0.05ml.
- This effective amount in about 250 to about 800 ml of water forms, if consumed by the animal is no more than about 250 to 1500 micrograms of iodine per day, an amount that is safe and effective for thyroid function.
- Embodiments of the present invention feature several sources of medicament. These sources may take the form of tanks, conduits and pumps.
- One embodiment features a tank, an integral vessel that receives external fluid containing medicaments.
- Another embodiment features a vessel as a replaceable consumable which is fitted to, or constructed and arranged to cooperate with conduits and/or pumps to communicate with, measuring means.
- One embodiment of the present invention comprises a tank or vessel which is pressurized to propel liquid medicament. Although reference is made to pumps or pressurized vessels, the fluid may move from the source of medicament to the measuring means by gravity feed without pressure and without pumps.
- Embodiments of the present invention feature measuring means such as a valve, a measuring vessel, a timed pump, metering syringe, and other apparatus for metering an aliquot of medicament.
- aliquot is a predetermined, desired amount of liquid.
- signal activation is used in a mechanical, photometric and electromagnetic sense.
- the term comprises mechanical linkages which compel a measuring vessel, valve, timed pump, metering syringe to dispense an aliquot of medicament.
- the term comprises wired, or wireless communication including WIFI, radio transmission, magnetic sensors and infrared devices which power or turn on pumps and valves and the like.
- Embodiments of the present invention feature administrative switch means comprising an on/off switch for an electrical circuit which operates measuring means, a mechanical link which operates a valve, measuring vessel, timed pump, metering syringe; or a photometric or electromagnetic sensor which detect the presence of the subject.
- the photometric or electromagnetic sensor is in signal communication with supporting control means to activate a valve, measuring vessel, metering syringe, timed pump or the like.
- Supporting control means is used in the sense of analog and digital equipment which receives signals from the sensor and in response to the signal issues an activation signal to measuring means.
- control means that detects subjects or animals.
- the sensors may detect the subject directly through optical or visual cues or detect a subject through tags or markers affixed to or associated with the subject.
- One embodiment of the present invention features a tag featuring an optical code, such as a bar code, which is sensed by administration switch means which comprises an optical scanner.
- administration switch means which comprises an optical scanner.
- One embodiment comprises a tag having a radio or optical coding device, for example, a RFID device, which is detected by a sensor.
- Tags and sensors which can detect a subject from a population of potential subjects are used in embodiments of the present invention to denote an identified subject or identified animal. Different tags having different codes are used to denote one of more identified animals from the potential population or separate identified animals for different medicaments or doses.
- Embodiments of the present invention feature administrative switching means having control means in the form of computer processing units (CPUs) integrated into a device comprising the measuring means as well as computers, servers, personal computers, internet linked computers and the like, in signal communication with measuring means but not integral therewith.
- control means having memory to store information regarding selected subjects and the administration of medicaments.
- Embodiments further comprise timing elements or clock functions and programming to administer medicament in accordance with a schedule.
- molecular iodine is administered to a selected subject or animal once or twice daily or more times daily.
- water reservoir means comprises a space constructed and arranged to receive a sized or shaped fluid receptacle, a fluid receptacle integral with the device or a disposable or removable cup, feeding and/or watering bowl or glass.
- Purge means removes medicament from the water reservoir.
- One embodiment of the invention features purge means in the form of a waste reservoir or adsorption materials such as filters and activated charcoal. Purge means can be constant or switched by a purge switch which directs the liquids in the water reservoir means to adsorption materials or into the waste reservoir. That is, the purge means is in signal communication with a purge switch means and is actuated by a purge signal.
- the purged switch means comprises a timed electrical or timed mechanical switch that is coordinated with the administration switch means, or a separate or combined with administration switch means, including incorporation of programming in control means such as a CPU. For example, without limitation, one control means is programmed issue a purge signal after an animal leaves the water reservoir.
- a further embodiment of the present invention is directed to a method for administering a medicament to an animal.
- the method comprising the steps of providing a device having a source of medicament in a fluid, measuring means, an administration switch, and water reservoir means as previously described.
- Embodiments of the present method are well suited for the administration of molecular iodine to the oral cavity of a subject such as a human or an animal.
- Figure 1 depicts a device embodying features of the present invention
- FIG. 2 depicts a schematic drawing having features of the present invention.
- FIG. 3 depicts a schematic drawing having features of the present invention. Detailed Description of the Invention
- Embodiments of the present invention feature devices and methods for administering a medicament to an animal or human. These embodiments will be described in detail as a device and method for administering molecular iodine to an animal, such as a dog, for the treatment of bad oral breath and preventing plaque formation. Those skilled in the art will recognize that embodiments of the present invention have application for the treatment of human disease and other animal and other diseases. The embodiments described are the best mode of the invention as presently contemplated. However, embodiments of the present invention can be modified and altered and the descriptions herein should not be considered limiting.
- the device 11 is for administering a medicament, molecular iodine, for the prevention or treatment of a disease, bad oral breath in a dog [not shown in Figure 1].
- the device 11 comprises a source of medicament in a fluid 13, measuring means 15, an administration switch 17 and a water reservoir means 19, held in a housing 21.
- the source of medicament 13 comprises a vessel containing molecular iodine in an ethanol solution.
- the molecular iodine is added to the water reservoir means 19 as an absolute alcohol solution saturated with I 2 .
- An effective amount of this solution is formed with 1.0 to 0.001 ml, more preferably, 0.1 to 0.025 ml, to about 0.05ml.
- This effective amount in about 500 ml of water forms, if consumed by the animal is no more than about 250 to 500 micrograms of iodine daily, an amount that is safe and effective for thyroid function and an amount that substantially disinfects the oral cavity of an animal.
- Sources of medicament 13 may take several forms, such as without limitation, tanks, conduits, pumps, bags, pouches, cartridges, vials, bottles, syringes and pressurized cans.
- Embodiments featuring a tank may incorporate the tank as an integral vessel that receives external fluid containing medicaments.
- a vessel can be a replaceable consumable which is fitted to, or constructed and arranged to cooperate with conduits and/or pumps to communicate with measuring means.
- Pressurized cans and containers may not need pumps and use compressed air to propel the medicament.
- the fluid may move from the source of medicament 13 to the measuring means 15 by gravity feed without pressure and without pumps.
- the source of medicament is a glass vessel containing ethanol saturated with molecular iodine.
- the measuring means 15 is in fluid communication with the source of medicament 13 for measuring an aliquot of medicament corresponding to a dose for the prevention of plaque or treatment of a disease.
- the term in "fluid communication” means plumbed together, or receiving fluid from one to the other.
- the measuring means 15 is also in communication with a water reservoir means and releases the aliquot into the water reservoir means 19 upon signal activation.
- the measuring means 15 comprises a timed or measured valve or pump, or metering syringe, or emptying a measuring vessel.
- the measuring means may take the form of a dispensing valve [not shown] known in the art of the type used for dispensing aerosols and fluids.
- the measuring means is a timed pump plumbed to the source of medicament 13 via medicament conduit 33a.
- the administration switch means 17 is in signal communication with the measuring means 15. Upon activation by a subject, such as a human or animal, administration switch means 17 produces an activation signal received by the measuring means 15. As best seen in Figure 2 which depicts signal communication of device 11, administration switch means 17 has an on/off switch 23 for an electrical circuit 25 which operates measuring means 17 in the form of a pump [not shown] and a purge means 51 to be described more fully below. In the alternative, the administration switch means operates a motor or solenoid [not shown] with a mechanical link to a valve, measuring vessel, timed pump, metering syringe [not shown]. The switch 23 is further in signal communication with a CPU 31 which has timing functions and scheduling programming.
- the timing function times the power to the pump or solenoid such that the pump, valve, measuring vessel or metered syringe dispenses a desired dose of medicament in the water reservoir means 19.
- the scheduling function will dispense medicament at selected times of the day and for individual subjects from a population of potential subjects.
- the administration switch means 17 of Figure 1 and Figure 2 further comprises a photometric or electromagnetic sensor which detects the presence of the subject.
- a photometric or electromagnetic sensor which detects the presence of the subject.
- one embodiment of the present invention comprises a camera [not shown] and CPU, such as CPU 31, with visual recognition software for detecting the presence of an animal.
- the photometric or electromagnetic sensor detects the presence of a tag 37.
- the tag 37 is recognized by sensor 39 by virtue of bar coding or other optical or electromagnetic coding.
- one embodiment of the present invention features a sensor such as an optical scanner.
- RFID tags are available from numerous vendors.
- a plurality of RFID tags 37 each coded separately for a plurality of individual subjects, are used to administer medicaments to selected or identified subjects from a population of potential subjects, at selected times or to receive selected medicaments.
- Tags and sensors which can detect a subject from a population of potential subjects are used in embodiments of the present invention to denote an identified subject or identified animal.
- Different tags having different codes are used to denote one of more identified animals from the potential population or separate identified animals for different medicaments or doses.
- control means can comprise other analog and digital equipment which receives signals from the sensor and in response to the signal issues an activation signal to measuring means 15.
- Embodiments of the present invention feature administrative switching means 17 having control means in the form of computer processing units (CPUs) integrated into a device 11.
- CPUs computer processing units
- CPU 31 may be located apart from the device 11, as a separate computers, server, personal computers, internet linked computers and the like, in signal communication with measuring means 15 by means of wired or wireless communication devices.
- Embodiments of the present invention feature control means such as CPU 31 having memory to store information regarding selected subjects and the administration of medicaments. Such memory is known in the art and is not shown for purposes of clarity.
- Embodiments further comprise timing elements or clock functions and programming to administer medicament in accordance with a schedule.
- Clock functions are common in CPU systems supporting CPU 31. Scheduling programming is also well known in the art.
- One embodiment of the present invention features molecular iodine administered to a selected subject or animal a schedule of once or twice daily. The doses are separated in time, for example eight to twelve hours. Programming is facilitated with a display screen 41 and controls 43 as best seen in Figure 1.
- the water reservoir means 19 is for receiving the aliquot and forming an aqueous solution of medicament.
- Water reservoir means 19 comprises a space constructed and arranged to receive a sized or shaped fluid receptacle, a fluid receptacle integral with the device or a disposable or removable cup, feeding and/or watering bowl or glass.
- the water reservoir means as depicted, is integral with the device 19 and comprises a basin 45 for holding a suitable amount of water, for example 100 to 800 ml.
- Water reservoir means 19 has a volume sensor 47 that detects when the basin 45 is at capacity or empty. The volume sensor 47 is in signal communication with CPU 31 which coordinates the administration switch means 17 and measuring means 15 such that medicament is not added to the basin 45 when basin 45 can not accommodate additional fluid or when the addition of medicament would not lead to an appropriate dilution.
- Water reservoir means 19 is in fluid communication with a source of water 71, best seen in Figure 3 which depicts a fluid diagram of device 11. The flow of which is controlled by a valve or siphon mechanism [not shown] known in the art and under signal control of the volume sensor 47 and CPU 31 or under hydrodynamic-mechanical control. Water flows into basin 45 via water inlet 67.
- the device 11 further comprises purge means 51 in communication with the water reservoir means 19.
- Purge means 51 removes medicament from the basin 45.
- purge means 51 comprises a drain 53, purge filter 55, purge conduits 57a-c, pump 59 and purge outlet 61. Liquid is removed from the basin 45 through drain 53 and conveyed by purge conduits 57a-c to a purge filter 55, purge pump 59 and on to the purge outlet 61.
- purge conduits 57a-c Liquid is removed from the basin 45 through drain 53 and conveyed by purge conduits 57a-c to a purge filter 55, purge pump 59 and on to the purge outlet 61.
- Purge filter 55 is made of porous materials to remove hair, dust and dirt. Purge filter 55 has an activated charcoal bed to remove medicament. Removal of medicament may be advantageous where the device 11 is used in the presence of small children.
- Purge means 51 may also comprise waste receptacles [not shown] for storing a volume of water. Removal of the water may obviate the need for a purge filter 55.
- Purge means 51 can be constant or switched by a purge switch [not shown] which directs the liquids in the water reservoir means to adsorption materials or into the waste reservoir.
- the purge pump 59 of purge means 51 is in signal communication with a purge switch means [not shown] and is actuated by a purge signal.
- the purge switch means comprises a timed electrical or timed mechanical switch that is coordinated with the administration switch means 17, or separate or combined with administration switch means 17, including incorporation of programming in control means such as a CPU 31.
- one control means is programmed to issue a purge signal after an animal leaves the water reservoir.
- the present device 11 is plumbed with a source of water 71 shown in Figure 3 which communicates with the basin 45 through a water inlet 67.
- Water inlet 67 releases water to fill basin 45 under the control of water level sensor 47 and CPU 31 or mechanical hydrodynamic means [not shown] known in the art.
- Embodiments of the present invention directed to a method for administering a medicament to an animal will be described in detail with respect to Figure 1 and device 11.
- the method comprising the steps of providing a device 11 having a source of medicament in a fluid 13, measuring means 15, an administration switch 17, and water reservoir means 19 as previously described.
- a subject such as a house pet, is fitted with a tag 37.
- administration switch means 17 recognizes the time the subject leaves the water reservoir means 19, and CPU 31 issues a purge signal to purge means 51 to remove medicament form the water reservoir means 19.
- Embodiments of the present method are well suited for the administration of molecular iodine to the oral cavity of a subject such as a human or an animal.
- One medicament is a saturated iodine in ethanol comprising iodine crystals and absolute ethanol.
- a 10% solution is prepared by dissolving 1 gram of iodine crystals in 100 ml of absolute ethanol.
- a 1% solution is prepared from al:10 dilution of the 10% solution of iodine in absolute ethanol.
- Two dogs and two cats were administered molecular iodine at doses ranging from 80-1400 meg iodine per day for one day and 1-5 meg per day for three weeks with no ill effects.
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- Biomedical Technology (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
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- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
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Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12752346.2A EP2670233A4 (de) | 2011-02-01 | 2012-02-01 | Vorrichtung und verfahren zur oralen verabreichung von desinfektionslösungen und anderen medikamenten |
US13/983,072 US9756832B2 (en) | 2010-02-02 | 2012-02-01 | Device and method for administering oral disinfecting solutions and other medicaments |
CA2826208A CA2826208C (en) | 2011-02-01 | 2012-02-01 | Device and method for administering oral disinfecting solutions and other medicaments |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/018,955 US8470303B2 (en) | 2010-02-02 | 2011-02-01 | Automated method and system for introducing molecular iodine into drinking water |
US13/018,995 | 2011-02-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2012118592A1 true WO2012118592A1 (en) | 2012-09-07 |
Family
ID=46758256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2012/023462 WO2012118592A1 (en) | 2010-02-02 | 2012-02-01 | Device and method for administering oral disinfecting solutions and other medicaments |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2670233A4 (de) |
CA (1) | CA2826208C (de) |
WO (1) | WO2012118592A1 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2023100048B4 (en) * | 2018-11-01 | 2024-01-04 | D.I.T Technologies Ltd | Dosing system with external flow sensor |
AU2023100049B4 (en) * | 2018-11-01 | 2024-02-08 | D.I.T Technologies Ltd | Dosing system for dosing urea phosphate and/or a methane reducer |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3870076A (en) * | 1973-03-26 | 1975-03-11 | Dacmont Inc | Automatic liquid medicament mixer for treating animals |
US5934221A (en) * | 1997-09-18 | 1999-08-10 | Kirschner; Jonathan | Device and method for watering a pet |
US6866005B1 (en) * | 2000-08-07 | 2005-03-15 | Trofftop Products Limited | Animal watering apparatus |
US20070080115A1 (en) * | 2005-10-11 | 2007-04-12 | Paul Sylvester | Sorbent for removal of contaminants from fluids |
US20080314335A1 (en) * | 2004-07-15 | 2008-12-25 | Lawrence Kates | Training and behavior controlling system for canines, felines, or other animals |
US20090081135A1 (en) * | 2007-09-24 | 2009-03-26 | Glen Jeffrey D | Iodine-based oral antibacterial treatment methodology |
US20090241848A1 (en) * | 2008-03-28 | 2009-10-01 | Dennis Bryant | Animal Waterer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2206622C (en) * | 1997-06-02 | 2001-12-11 | Iosolutions Incorporated | Method of disinfecting water with iodine species |
US6427627B1 (en) * | 2000-03-17 | 2002-08-06 | Growsafe Systems Ltd. | Method of monitoring animal feeding behavior |
US20040084096A1 (en) * | 2002-11-06 | 2004-05-06 | Whaley T. Keith | Water supply medicator |
WO2010091686A1 (en) * | 2008-12-15 | 2010-08-19 | Aarhus Universitet Det Jordbrugsvidenskabelige Fakultet | An apparatus and method for surveillance of individual animals' liquid intake behaviour |
DE102009018324B4 (de) * | 2009-04-22 | 2010-12-30 | Hafner, Ullrich, Dipl.-Ing. (FH) | Tiertränke |
-
2012
- 2012-02-01 EP EP12752346.2A patent/EP2670233A4/de not_active Withdrawn
- 2012-02-01 CA CA2826208A patent/CA2826208C/en active Active
- 2012-02-01 WO PCT/US2012/023462 patent/WO2012118592A1/en active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3870076A (en) * | 1973-03-26 | 1975-03-11 | Dacmont Inc | Automatic liquid medicament mixer for treating animals |
US5934221A (en) * | 1997-09-18 | 1999-08-10 | Kirschner; Jonathan | Device and method for watering a pet |
US6866005B1 (en) * | 2000-08-07 | 2005-03-15 | Trofftop Products Limited | Animal watering apparatus |
US20080314335A1 (en) * | 2004-07-15 | 2008-12-25 | Lawrence Kates | Training and behavior controlling system for canines, felines, or other animals |
US20070080115A1 (en) * | 2005-10-11 | 2007-04-12 | Paul Sylvester | Sorbent for removal of contaminants from fluids |
US20090081135A1 (en) * | 2007-09-24 | 2009-03-26 | Glen Jeffrey D | Iodine-based oral antibacterial treatment methodology |
US20090241848A1 (en) * | 2008-03-28 | 2009-10-01 | Dennis Bryant | Animal Waterer |
Non-Patent Citations (1)
Title |
---|
See also references of EP2670233A4 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2023100048B4 (en) * | 2018-11-01 | 2024-01-04 | D.I.T Technologies Ltd | Dosing system with external flow sensor |
AU2023100049B4 (en) * | 2018-11-01 | 2024-02-08 | D.I.T Technologies Ltd | Dosing system for dosing urea phosphate and/or a methane reducer |
Also Published As
Publication number | Publication date |
---|---|
CA2826208A1 (en) | 2012-09-07 |
CA2826208C (en) | 2020-02-25 |
EP2670233A4 (de) | 2017-01-04 |
EP2670233A1 (de) | 2013-12-11 |
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