WO2012057497A3 - Appareil de collecte de cellules - Google Patents

Appareil de collecte de cellules Download PDF

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Publication number
WO2012057497A3
WO2012057497A3 PCT/KR2011/007976 KR2011007976W WO2012057497A3 WO 2012057497 A3 WO2012057497 A3 WO 2012057497A3 KR 2011007976 W KR2011007976 W KR 2011007976W WO 2012057497 A3 WO2012057497 A3 WO 2012057497A3
Authority
WO
WIPO (PCT)
Prior art keywords
target cells
conduit
collected
fluid samples
screen filter
Prior art date
Application number
PCT/KR2011/007976
Other languages
English (en)
Korean (ko)
Other versions
WO2012057497A2 (fr
Inventor
전병희
이종길
Original Assignee
주식회사 싸이토젠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020100104249A external-priority patent/KR101276187B1/ko
Priority claimed from KR1020100104250A external-priority patent/KR101254677B1/ko
Application filed by 주식회사 싸이토젠 filed Critical 주식회사 싸이토젠
Priority to US13/881,719 priority Critical patent/US20130264272A1/en
Priority to CN201180062660.7A priority patent/CN103270150B/zh
Priority to JP2013536504A priority patent/JP5800910B2/ja
Priority to EP11836589.9A priority patent/EP2634244A4/fr
Publication of WO2012057497A2 publication Critical patent/WO2012057497A2/fr
Publication of WO2012057497A3 publication Critical patent/WO2012057497A3/fr
Priority to US15/349,922 priority patent/US10473567B2/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4005Concentrating samples by transferring a selected component through a membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403Regulation parameters
    • A61M1/341Regulation parameters by measuring the filtrate rate or volume
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D39/00Filtering material for liquid or gaseous fluids
    • B01D39/10Filter screens essentially made of metal
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4005Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un filtre à tamis pour collecter des cellules cibles par séparation d'échantillons de fluide, notamment de fluides sanguins, physiologiques etc. L'invention comprend un conduit présentant une paroi tubulaire et un passage pour transporter des échantillons de fluide qui contiennent des cellules souches, et un filtre à tamis à plusieurs orifices de filtration situé dans le conduit pour filtrer des cellules cibles de sorte que le flux de cellules cibles est induit de manière à collecter ces dernières. Par conséquent, le taux d'échantillonnage de cellules cibles est hautement accru, et ainsi les cellules cibles peuvent être prélevées à partir de sang humain et être adaptées de manière utile pour une analyse, un test, des essais pharmacologiques ou cliniques, etc.
PCT/KR2011/007976 2010-10-25 2011-10-25 Appareil de collecte de cellules WO2012057497A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US13/881,719 US20130264272A1 (en) 2010-10-25 2011-10-25 Cell collecting device
CN201180062660.7A CN103270150B (zh) 2010-10-25 2011-10-25 细胞采集装置
JP2013536504A JP5800910B2 (ja) 2010-10-25 2011-10-25 細胞採集装置
EP11836589.9A EP2634244A4 (fr) 2010-10-25 2011-10-25 Appareil de collecte de cellules
US15/349,922 US10473567B2 (en) 2010-10-25 2016-11-11 Cell collecting device

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2010-0104250 2010-10-25
KR10-2010-0104249 2010-10-25
KR1020100104249A KR101276187B1 (ko) 2010-10-25 2010-10-25 세포 채집 장치
KR1020100104250A KR101254677B1 (ko) 2010-10-25 2010-10-25 세포 채집 장치

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/881,719 A-371-Of-International US20130264272A1 (en) 2010-10-25 2011-10-25 Cell collecting device
US15/349,922 Continuation US10473567B2 (en) 2010-10-25 2016-11-11 Cell collecting device

Publications (2)

Publication Number Publication Date
WO2012057497A2 WO2012057497A2 (fr) 2012-05-03
WO2012057497A3 true WO2012057497A3 (fr) 2012-07-26

Family

ID=45994539

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/007976 WO2012057497A2 (fr) 2010-10-25 2011-10-25 Appareil de collecte de cellules

Country Status (5)

Country Link
US (2) US20130264272A1 (fr)
EP (1) EP2634244A4 (fr)
JP (1) JP5800910B2 (fr)
CN (1) CN103270150B (fr)
WO (1) WO2012057497A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101317311B1 (ko) * 2013-02-26 2013-10-10 임욱빈 블로윙 방식을 이용한 검진 대상물 착상 장치
FR3005163A1 (fr) * 2013-04-24 2014-10-31 Biomerieux Sa Dispositif de filtration et concentration automatique de microorganismes.
US11033896B2 (en) 2014-08-08 2021-06-15 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device with filtration flow control
CN104188668B (zh) * 2014-08-11 2016-08-17 丽水市人民医院 血液细菌收集装置
WO2016025709A1 (fr) * 2014-08-13 2016-02-18 Oregon Health & Science University Dispositif de collecte de tache de sang séché
CN104498346A (zh) * 2014-12-12 2015-04-08 张群 基于微米孔的健康精子快速筛选收集器件及其使用方法
WO2016208459A1 (fr) * 2015-06-22 2016-12-29 株式会社村田製作所 Dispositif de filtration, procédé de filtration, et filtre de filtration
WO2016208752A1 (fr) * 2015-06-26 2016-12-29 株式会社村田製作所 Dispositif et procédé de filtrage
WO2016208753A1 (fr) * 2015-06-26 2016-12-29 株式会社村田製作所 Dispositif et procédé de filtrage
CN106795470A (zh) * 2015-08-06 2017-05-31 株式会社奥普特尼克斯精密 细胞分离过滤器及细胞培养容器
JP6142042B1 (ja) 2016-03-18 2017-06-07 株式会社村田製作所 有核細胞の濾過用フィルターおよびそれを用いた濾過方法
WO2017159367A1 (fr) * 2016-03-18 2017-09-21 株式会社村田製作所 Membrane poreuse métallique, et procédé de classification et dispositif de classification utilisant celle-ci
JP2019092393A (ja) * 2016-04-15 2019-06-20 株式会社カネカ 細胞懸濁液調製用容器および細胞懸濁液の調製方法
JP6443604B1 (ja) * 2017-03-10 2018-12-26 株式会社村田製作所 細胞濾過フィルタ
JP6936467B2 (ja) * 2017-03-16 2021-09-15 株式会社オプトニクス精密 フィルタ装置
JP6249124B1 (ja) * 2017-04-26 2017-12-20 株式会社村田製作所 有核細胞の濾過用フィルターおよびそれを用いた濾過方法
WO2019059279A1 (fr) * 2017-09-20 2019-03-28 株式会社カネカ Dispositif, système et méthode pour préparer une suspension cellulaire
JP6815307B2 (ja) * 2017-11-09 2021-01-20 株式会社村田製作所 有核細胞の濾過用フィルターおよびそれを用いた濾過方法
WO2019181158A1 (fr) * 2018-03-19 2019-09-26 株式会社村田製作所 Filtre de filtration et dispositif de filtration
CA3107736C (fr) * 2018-07-28 2023-10-17 Leavitt Medical, Inc. Procedes et systemes de preparation d'echantillons cytologiques
IL297622A (en) * 2020-05-12 2022-12-01 Pbs Biotech Inc Material transfer devices and related systems and methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043082A (en) * 1988-12-15 1991-08-27 Hermann Jr William J Collection device and method of use thereof for the concentration, transport and processing of cellular components to determine the presence or absence of biomarkers
US5861094A (en) * 1997-04-17 1999-01-19 Goehde; Wolfgang Filter for biological particle separation
JP2006305517A (ja) * 2005-05-02 2006-11-09 Denso Corp フィルタ装置

Family Cites Families (12)

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US1801934A (en) * 1928-04-16 1931-04-21 Pearson Fred Garbage receptacle
US3834539A (en) * 1972-12-26 1974-09-10 C Thompson Trap for removing solid particles from a liquid circulating system
US4264446A (en) * 1979-08-06 1981-04-28 Fregeau Jack J Strainer screen
US5240861A (en) * 1988-07-29 1993-08-31 Spectrum Medical Industries, Inc. Device and process for concentrating biologic specimens in liquid form
US5944991A (en) * 1997-11-21 1999-08-31 Dresser Industries, Inc. Pipeline strainer
US7846743B2 (en) 2005-04-21 2010-12-07 California Institute Of Technology Uses of parylene membrane filters
EP1897570A1 (fr) * 2006-09-08 2008-03-12 Gelanus B.V. Dispositif de récupération du sang et méthode
EP2238232B1 (fr) 2008-01-29 2019-08-14 California Institute of Technology Procédé et appareil de microfiltration pour effectuer une séparation de cellules
CN101329231B (zh) * 2008-08-01 2010-07-07 张震 一种锥形过滤器及全脱落细胞自动收集仪
CN101785883A (zh) * 2009-11-12 2010-07-28 赛普瑞特科技开发(北京)有限公司 一种肿瘤患者自体血液回输方法及用于此方法的肿瘤细胞过滤器
US20130071304A1 (en) * 2010-04-15 2013-03-21 Cytogen Co., Ltd. Microfluidic device
JP2012065590A (ja) * 2010-09-24 2012-04-05 Olympus Corp 細胞処理装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5043082A (en) * 1988-12-15 1991-08-27 Hermann Jr William J Collection device and method of use thereof for the concentration, transport and processing of cellular components to determine the presence or absence of biomarkers
US5861094A (en) * 1997-04-17 1999-01-19 Goehde; Wolfgang Filter for biological particle separation
JP2006305517A (ja) * 2005-05-02 2006-11-09 Denso Corp フィルタ装置

Also Published As

Publication number Publication date
EP2634244A2 (fr) 2013-09-04
EP2634244A4 (fr) 2017-03-22
JP2013541958A (ja) 2013-11-21
JP5800910B2 (ja) 2015-10-28
US20130264272A1 (en) 2013-10-10
CN103270150A (zh) 2013-08-28
WO2012057497A2 (fr) 2012-05-03
CN103270150B (zh) 2016-10-19
US10473567B2 (en) 2019-11-12
US20170059460A1 (en) 2017-03-02

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