WO2012039350A1

WO2012039350A1 - Skin cleanser composition

Info

Publication number: WO2012039350A1
Application number: PCT/JP2011/071189
Authority: WO
Inventors: 恭史柿澤; 光俊森部; 幸治二宮
Original assignee: ライオン株式会社
Priority date: 2010-09-21
Filing date: 2011-09-16
Publication date: 2012-03-29
Also published as: KR20130110157A; TW201302226A; TWI515013B; KR101790822B1; JPWO2012039350A1; JP5861639B2

Abstract

Provided is a skin cleanser composition in a liquid crystal state which has high stability in hot and cold storage and shows good usability even handled with wet hands, namely, a skin cleanser composition characterized by containing components (A), (B), (C) and (D) and being in a liquid crystal state at 25°C. (A) 15-45 mass% of a higher fatty acid salt having 8 to 26 carbons. (B) 7-25 mass% of a betaine type amphoteric surfactant. (C) 1-5 mass% of a nonionic surfactant as specified below: a compound wherein 3 hydroxyl groups of polyoxyethylene glyceryl, glycerol or polyoxyethylene trimethylolpropane are esterified or etherified and the esterified or etherified moiety is a monovalent hydrocarbon group having 7-25 carbons. (D) 15-35 mass% of a polyhydric alcohol.

Description

Skin cleanser composition

The present invention relates to a skin cleansing composition in a liquid crystal state, which is excellent in stability during storage at high temperatures and low temperatures and has good usability even when the hand is wet.

The semi-solid detergent composition can keep particles such as scrubs dispersed in the preparation, and can improve the appearance and feel. Among these, a gel-like cleaning agent having a transparent to translucent appearance can provide consumers with a high quality feeling.

The detergent composition containing a higher fatty acid salt is excellent in foam performance and rinsing performance, but has a problem that performance and stability are poor when it is semi-solid. For example, a transparent gel-like skin cleanser using a higher fatty acid salt and an alkyl acrylate copolymer has been proposed (Patent Document 1: JP 2007-126396 A). However, although the appearance is a transparent gel, it is thickened with a polymer compound to form a gel, so that foaming is slow and the usability is poor because a thread is pulled when picking up the preparation.

Further, a transparent gel-like cleaning agent using a specific higher fatty acid salt, an amphoteric surfactant, glycerin and a fatty acid alkanolamide type nonionic surfactant has been proposed (Patent Document 2: JP-A-2007-511168). Publication). This is not a thickening due to the polymer compound but gelation by the liquid crystal phase of the surfactant, so stringing during use is difficult to occur, but it is difficult to remove from the container due to its high viscosity, and water was added. In some cases, the preparation is difficult to extend and falls from the hand.

JP 2007-126396 A JP 2007-511168 A

The present invention has been made in view of the above circumstances, and an object thereof is to provide a skin cleansing composition in a liquid crystal state that has excellent stability during storage at high temperatures and low temperatures and has good usability even when the hands are wet. And

As a result of intensive studies to achieve the above object, the present inventors have found that (A) a higher fatty acid salt, (B) a betaine amphoteric surfactant, (C) a specific nonionic surfactant, D) A specific amount of each of the polyhydric alcohols is blended, and a transparent skin cleanser composition in a liquid crystal state at 25 ° C. is excellent in stability at high and low temperature storage, and the hands are wet. It has been found that good usability (easiness of melting, foaming) is possible even in a state, and the present invention has been made.

Accordingly, the present invention provides the following skin cleanser composition.
[1]. A skin cleanser composition containing the following components (A), (B), (C) and (D) and in a liquid crystal state at 25 ° C.
(A) 15 to 45% by mass of higher fatty acid salt having 8 to 26 carbon atoms
(B) Betaine amphoteric surfactant 7 to 25% by mass
(C) 1 to 5% by mass of the following nonionic surfactant
Three hydroxyl groups of polyoxyethylene (average added mole number of ethylene oxide 10 to 80) glyceryl, glycerin, or polyoxyethylene (average added mole number of ethylene oxide 10 to 80) trimethylolpropane are esterified or etherified. The esterified or etherified moiety is a saturated or unsaturated, linear or branched monovalent hydrocarbon group having 7 to 25 carbon atoms, and part of the hydrogen atoms are substituted with hydroxyl groups. The polyoxyethylene having an average addition mole number of 10 to 80 may be added to this hydroxyl group, provided that the total number of polyoxyethylene added to the nonionic surfactant is the average addition mole number. 10 to 80.
(D) 15 to 35% by mass of polyhydric alcohol
[2]. The skin cleanser according to [1], wherein the component (C) is a monovalent hydrocarbon group having 7 to 25 carbon atoms in the esterified or etherified moiety, wherein a part of the hydrogen atoms is substituted with a hydroxyl group Agent composition.
[3]. (C) The skin cleaning composition according to [1] or [2], wherein the component is polyoxyethylene hydrogenated castor oil or polyoxyethylene castor oil.
[4]. The skin cleanser composition according to [1], [2] or [3], wherein the liquid crystal is hexagonal liquid crystal.

According to the present invention, it is possible to provide a liquid-form skin cleanser composition that has excellent stability during storage at high and low temperatures and has good usability even when the hand is wet.

Hereinafter, the present invention will be described in detail.
The skin cleanser composition of the present invention is a skin cleanser composition containing the following components (A), (B), (C) and (D) and being in a liquid crystal state at 25 ° C. .
(A) 15 to 45% by mass of higher fatty acid salt having 8 to 26 carbon atoms
(B) Betaine amphoteric surfactant 7 to 25% by mass
(C) 1 to 5% by mass of the following nonionic surfactant
Three hydroxyl groups of polyoxyethylene (average added mole number of ethylene oxide 10 to 80) glyceryl, glycerin, or polyoxyethylene (average added mole number of ethylene oxide 10 to 80) trimethylolpropane are esterified or etherified. The esterified or etherified moiety is a saturated or unsaturated, linear or branched monovalent hydrocarbon group having 7 to 25 carbon atoms, and part of the hydrogen atoms are substituted with hydroxyl groups. The polyoxyethylene having an average addition mole number of 10 to 80 may be added to this hydroxyl group, provided that the total number of polyoxyethylene added to the nonionic surfactant is the average addition mole number. 10 to 80.
(D) 15 to 35% by mass of polyhydric alcohol

(A) Higher fatty acid salt The (A) higher fatty acid salt of the present invention is a higher fatty acid salt having 8 to 26 carbon atoms, and the monovalent hydrocarbon group moiety is either linear or branched, saturated or unsaturated. It may be used alone or in combination of two or more. Among these, higher fatty acid salts represented by the following general formula (1) are preferable.
R ¹ COOM (1)
(In the formula, R ¹ represents a linear or branched, saturated or unsaturated monovalent hydrocarbon group having 7 to 25 carbon atoms, and part or all of the hydrogen atoms of the monovalent hydrocarbon group are hydroxyl groups. (M may be potassium, sodium, monoethanolamine, diethanolamine, triethanolamine, 2-amino-2-methyl-1-propanol or diisopropanolamine.)

Component (A) includes caproic acid, heptanoic acid, caprylic acid, pelargonic acid, capric acid, undecanoic acid, lauric acid, caproleic acid, undecylenic acid, lauroleic acid, 2-ethylbutanoic acid, isopentanoic acid, 2-ethylpentanoic acid 2-ethylhexanoic acid, isononanoic acid, 3,5,5-trimethylhexanoic acid, tridecanoic acid, tetramethylnonanoic acid, myristic acid, pentadecanoic acid, palmitic acid, stearic acid, arachidic acid, behenic acid, lignoceric acid, cellotine Acid, myristoleic acid, palmitoleic acid, oleic acid, elaidic acid, gondoic acid, erucic acid, cerakoleic acid, linoleic acid, linoelaidic acid, linolenic acid, arachidonic acid, 2-hexyldecanoic acid, isostearic acid, 12-hydroxystearic acid Laurin , Myristic acid, palmitic acid, salts of coconut oil fatty acids are mixtures of such capric acid.

Of these, caprates, laurates, myristates and palmitates having 10, 12, 14, and 16 carbon atoms are preferred. If the number of carbon atoms is less than 10, the stability at high temperature is poor, and if it exceeds 16, the stability at low temperature may be poor. The mass ratio of the higher fatty acid salt having 12 or less carbon atoms and the higher fatty acid salt having 14 or more carbon atoms is preferably 80/20 to 40/60, more preferably 75/25 to 50/50, and 70/30 to 60 / 40 is more preferable. When the ratio of the higher fatty acid salt having 12 or less carbon atoms exceeds 80/20, the high temperature stability is poor, and when it is less than 40/60, the low temperature stability and the solubility in water may be deteriorated.

M (counter ion) forms a COOM salt. As M, potassium, sodium, monoethanolamine, diethanolamine, and triethanolamine are preferable from the viewpoint of low-temperature stability, and potassium and monoethanolamine are more preferable from the viewpoint of low-temperature stability. From the viewpoint of bactericidal activity and low-temperature stability, when the amount of higher fatty acid salt is 100% by mass, the proportion of monoethanolamine salt is preferably 1 to 35% by mass, more preferably 3 to 15% by mass. .

The content of component (A) is 15 to 45% by mass in the skin cleanser composition. If it is less than 15% by mass, no liquid crystal is formed. On the other hand, when it exceeds 45 mass%, a precipitate is produced at a low temperature. Further, from the viewpoint of foaming and low-temperature stability, 17 to 40% by mass, particularly 20 to 35% by mass, and particularly 25 to 35% by mass are preferable.

(B) Betaine-type amphoteric surfactant Examples of the betaine-type amphoteric surfactant include imidazoline type (amidoamine type), carbobetaine type, sulfobetaine type, and phosphobetaine type. These can be used individually by 1 type or in combination of 2 or more types. Among these, the carbobetaine type is preferable in that it easily forms liquid crystals.

Examples of the carbobetaine type include alkyl betaines such as lauryl betaine and lauryl dimethylaminoacetic acid betaine, alkylamide betaines such as lauric acid amidopropyl betaine and coconut oil fatty acid amidopropyl betaine. Among these, lauryl dimethylaminoacetic acid betaine and lauric acid amidopropyl betaine are more preferable from the viewpoint of liquid crystal formability, and lauryldimethylaminoacetic acid betaine is particularly preferable from the viewpoint of low-temperature stability. The amphoteric surfactant may contain sodium chloride in the production process, and is desalted from the viewpoint of improving low-temperature stability, so that sodium chloride is reduced to 1% by mass or less in the amphoteric surfactant aqueous solution. Is more preferable.

The content of component (B) is 7 to 25% by mass, preferably 9 to 15% by mass, in the skin cleanser composition. If it is less than 7% by mass, no liquid crystal is formed, and if it exceeds 25% by mass, precipitation tends to occur at a low temperature.

(C) The following nonionic surfactant The component (C) of the present invention contains polyoxyethylene (average added mole number of ethylene oxide 10 to 80) glyceryl, glycerin, or polyoxyethylene (average added mole number of ethylene oxide) 10 to 80) A compound in which three hydroxyl groups of trimethylolpropane are esterified or etherified, and the esterified or etherified moiety is a saturated or unsaturated, linear or branched chain having 7 to 25 carbon atoms. It is a monovalent hydrocarbon group, a part of hydrogen atoms may be substituted with a hydroxyl group, and polyoxyethylene having an average addition mole number of 10 to 80 may be added to this hydroxyl group, provided that it is nonionic The total number of polyoxyethylenes added to the surfactant is 10-80 in terms of the average number of moles added.

When the number of esterified or etherified hydroxyl groups is 2 or less, the solubility of the preparation in water decreases. The total number of polyoxyethylenes added to the nonionic surfactant is more preferably 15 to 40 mol. If the amount is less than 10 moles, the solubility of the preparation in water and the low-temperature stability may decrease, and the cloudiness may result in loss of transparency. If the amount exceeds 80 moles, the high-temperature stability is deteriorated.

Among them, nonionic surfactants (i) to (iii) having the following structures are excellent in stability during storage at high temperatures and low temperatures, and have good usability even when the hands are wet. It is preferable because a cleaning composition can be obtained.

(I) Polyoxyethylene (average addition mole number of ethylene oxide: 10 to 80) A compound in which three hydroxyl groups of glyceryl are esterified or etherified, wherein the esterified or etherified moiety has 7 to 25 carbon atoms. A saturated or unsaturated, linear or branched monovalent hydrocarbon group, in which part of the hydrogen atoms may be substituted with a hydroxyl group, and the polyoxyethylene having an average addition mole number of 10 to 80 May be added to the nonionic surfactant (however, the total number of polyoxyethylene added to the nonionic surfactant is from 10 to 80 in terms of the average number of moles added).

Examples of the nonionic surfactant corresponding to the above (i) include PEG-20 glyceryl triisostearate, PEG-20 glyceryl tristearate, PEG-20 glyceryl trioleate, and the like.

(Ii) A compound in which three hydroxyl groups of glycerin are esterified or etherified, and the esterified or etherified moiety is a saturated or unsaturated, linear or branched monovalent carbonization having 7 to 25 carbon atoms. Nonionic surfactant in which a part of hydrogen atom is substituted with a hydroxyl group, and polyoxyethylene having an average addition mole number of 10 to 80 is added to this hydroxyl group (however, nonionic surfactant The total number of polyoxyethylenes added to is an average addition mole number of 10 to 80).

Nonionic surfactants corresponding to the above (ii) include polyoxyethylene hydrogenated castor oil (EO.10), polyoxyethylene castor oil (EO.20), polyoxyethylene hydrogenated castor oil ( EO20), polyoxyethylene hydrogenated castor oil (EO40), polyoxyethylene castor oil (EO40), polyoxyethylene hydrogenated castor oil (EO80), and the like. It is done.

(Iii) Polyoxyethylene (average addition mole number of ethylene oxide 10 to 80) A compound in which three hydroxyl groups of trimethylolpropane are esterified or etherified, wherein the esterified or etherified moiety has a carbon number of 7 A saturated or unsaturated, linear or branched monovalent hydrocarbon group having from 25 to 25, a part of the hydrogen atoms may be substituted with a hydroxyl group, and an average added mole number of 10 to 80 is added to the hydroxyl group. Nonionic surfactant to which oxyethylene may be added (however, the total number of polyoxyethylene added to the nonionic surfactant is 10 to 80 in terms of the average number of moles added)

Examples of the nonionic surfactant corresponding to the above (iii) include PEG-20 trimethylolpropane triisostearate.

Specific examples include the following. Hereinafter, PEG represents polyethylene glycol, and POE represents polyoxyethylene. For example, POE (20) shows an average addition mole number of polyoxyethylene of 20.
PEG-20 glyceryl triisostearate (Japan emulsion, GWIS-320) HLB = 8
PEG-20 glyceryl tristearate (Japan Emulsion, GWS-320, HLB = 8)
PEG-20 glyceryl trioleate (Japan Emulsion, GWO-320, HLB = 8)
PEG-20 trimethylolpropane triisostearate (Japan emulsion, TPIS-320, HLB = 8)
POE (20) castor oil (Japanese emulsion, C-20, HLB = 9)
POE (10) hydrogenated castor oil (Japan emulsion, HC-10, HLB = 7)
POE (10) hydrogenated castor oil (Nikko Chemicals, HCO-10, HLB = 6.5)
POE (20) hydrogenated castor oil (Japan emulsion, HC-20, HLB = 9)
POE (20) hydrogenated castor oil (Nikko Chemicals, HCO-20, HLB = 10.5)
POE (40) hydrogenated castor oil (Japan emulsion, HC-40, HLB = 12)
POE (40) hydrogenated castor oil (Nikko Chemicals, HCO-40, HLB = 12.5)
POE (80) hydrogenated castor oil (Japan emulsion, HC-80, HLB = 15)
POE (80) hydrogenated castor oil (Nikko Chemicals, HCO-80, HLB = 15.0)

The esterified or etherified moiety is a monovalent hydrocarbon group having 7 to 25 carbon atoms, preferably 16 to 20 carbon atoms, and the monovalent hydrocarbon group may be saturated or unsaturated, linear or branched, A part of hydrogen atoms may be substituted with a hydroxyl group. From the viewpoint of solubility of the preparation in water, a branched hydrocarbon chain or a hydrocarbon chain having a hydroxyl group at a portion other than the terminal of the hydrocarbon chain is more preferable. Especially, the nonionic surfactant corresponding to said (ii) is more preferable at the point of the solubility of a formulation to water, and polyoxyethylene hydrogenated castor oil and polyoxyethylene castor oil are more preferable. The esterified fatty acid residue portion of polyoxyethylene castor oil (the portion combining the hydrocarbon chain and the ester group) is an unsaturated fatty acid (87% by mass of ricinoleic acid, 7% by mass of oleic acid, and linoleic acid 3 mass%) and a small amount of saturated fatty acid (palmitic acid, stearic acid 3 mass%). In the case of hydrogenated castor oil, the fatty acid is hydrogenated. In particular, from the viewpoint of the solubility of the preparation in water, it is preferable that the fatty acid distribution of the fatty acid residue contains 80% by mass or more of ricinoleic acid having a hydroxyl group at position 12 or a hydrogenated product thereof.

Among them, polyoxyethylene hydrogenated castor oil (EO.20) [POE (20) hydrogenated castor oil], polyoxyethylene hydrogenated castor oil (E.O.40) [POE (40) hydrogenated castor oil], polyoxy Ethylene castor oil (E.O.20) [POE (20) castor oil], POE (40) castor oil [POE (40) castor oil] have excellent stability during high-temperature and low-temperature storage and wet hands It is most preferable from the viewpoint that a liquid skin cleansing composition having good usability even in a state can be obtained. The mechanism is unknown, but POE hydrogenated castor oil and POE castor oil are considered to have loosened the liquid crystal structure because of the structure in which the polyoxyethylene chain is branched from the hydroxyl group present in the hydrocarbon group.

The content of component (C) is 1 to 5% by mass, particularly 2 to 4% by mass, and particularly preferably 2 to 3% by mass in the skin cleanser composition. If it is less than 1% by mass, the preparation is not sufficiently soluble in water, and if it exceeds 5% by mass, the high-temperature stability is deteriorated.

(D) Polyhydric alcohol The polyhydric alcohol is preferably a dihydric to hexahydric one, such as ethylene glycol, diethylene glycol, polyethylene glycol 200 (a quasi-drug raw material standard 2006 equivalent), polyethylene glycol 300 (a quasi-drug raw material). Standard 2006 equivalent), polyethylene glycol 400 (quasi-drug raw material standard 2006 equivalent), polyethylene glycol 600 (quasi-drug raw material standard 2006 equivalent), propylene glycol, dipropylene glycol, 1,3-butylene glycol, Isopentyldiol, pentylene glycol, 1,2-hexanediol, hexylene glycol, glycerin, diglycerin, sorbit, xylitol, mannitol and the like are preferable, and these are used alone or in appropriate combination of two or more. Can be used. Here, the polyethylene glycol corresponds to those defined in Cosmetic Material Standard 2nd Edition Comment, Quasi-drug Raw Material Standard 2006, Japanese Pharmacopoeia Pharmaceutical Standard 2002, 15th revised Japanese Pharmacopoeia. Among these, propylene glycol, polyethylene glycol 200, polyethylene glycol 300, polyethylene glycol 400, polyethylene glycol 600, propylene glycol, glycerin, and sorbit are preferable from the viewpoint of easy formation of liquid crystals. Furthermore, from the viewpoint of low temperature stability and easy formation of liquid crystals, a mixture of divalent and trivalent polyhydric alcohols is more preferable, a combination of propylene glycol and glycerin is more preferable, and the mass (%) of propylene glycol / glycerin The mass (%) is particularly preferably 20/80 to 50/50. When the ratio of propylene glycol exceeds 50/50, the liquid crystal formability may be lowered and high-temperature stability may be lowered, and when it is less than 20/80, the viscosity may be too high.

The content of component (D) is 15 to 35% by mass, preferably 20 to 30% by mass, in the skin cleanser composition. If it is less than 15% by mass, the low-temperature stability is poor, and if it exceeds 35% by mass, it becomes difficult to form a liquid crystal.

The mass ratio of (A) higher fatty acid salt and (B) betaine-type amphoteric surfactant is preferably 85/15 to 60/40. When the ratio of the component (A) exceeds 85/15, the stability at low temperatures may be deteriorated, and when it is less than 60/40, it may cause luster during rinsing.

The mass ratio of (A) higher fatty acid salt and (D) polyhydric alcohol is preferably 70/30 to 40/60. When the ratio of the component (A) exceeds 70/30, the low temperature stability may be deteriorated, and when it is less than 40/60, the high temperature stability and transparency may be deteriorated.

The skin cleanser composition of the present invention is in a liquid crystal state at 25 ° C. In the present invention, the liquid crystal refers to hexagonal liquid crystal, lamellar liquid crystal, and cubic liquid crystal. Among these, hexagonal liquid crystals are preferable in terms of usability and a transparent appearance. A lamellar liquid crystal has a low viscosity and hangs down from the hand during use or thickens with added water, which may deteriorate the usability.

In the present invention, “liquid crystal” is a molecular assembly of surfactants, and a liquid crystal state in which a cylindrical surfactant becomes a rod-like molecule due to the presence of an ionic polymer compound having a high concentration or an opposite charge. Say. Such anisotropy based on this orientation order exhibited by the liquid crystal is “spontaneous” derived from the shape of the molecule and intermolecular force, and is not induced by any external force. When a flow is applied to a concentrated solution of a polymer compound, molecular orientation occurs and optical anisotropy is observed. However, when the flow stops, such orientation is not spontaneous. Liquid crystals are extremely peculiar in that they have both liquid properties of fluidity and liquid crystal properties of optical anisotropy, and cannot be classified as solid or liquid. It is considered to be the “fourth state” of the substance.

Confirmation of the “liquid crystal state” can be judged from observation of interference patterns with a polarizing microscope. When the interference pattern is observed as a scaly mosaic texture, it is a hexagonal liquid crystal, when a cross-shaped cross Nicol is observed, it is a lamellar liquid crystal, and when no interference pattern is observed, it is a micellar phase or a cubic phase. These typical interference patterns are illustrated in RBO Rosevere, “The microscopy of the Liquid Crystalline Neat and Middle Phase of soaps and synthetic detergents” J. Am. Oil Chemist's Soc., 628, 31 (1954). In addition, when a solid substance is seen at 25 degreeC, even if these interference patterns are seen, it is not judged as a liquid crystal phase. On the other hand, when it is difficult to determine a cubic layer with very high viscosity and no interference pattern, or when it is difficult to determine with a polarizing microscope, it can be determined from the interference pattern of small-angle X-ray scattering. Corresponding to the (100), (110), (200) planes, a hexagonal liquid crystal phase has a peak at a scattering angle corresponding to a distance ratio of 1: √3: 2:. , (200), (300) corresponding to the plane spacing ratio of 1: 2: 3:... Is a lamellar liquid crystal, (100), (111), (200 ) 1: √3 / 2 corresponding to the surface spacing of the surfaces: √2:..., And 1: √4 / 3 corresponding to the (211), (220), (321), (400) surfaces: A liquid crystal having a peak at √7 / 3: √8 / 3:... Is cubic liquid crystal. In addition, when no clear peak is observed in the X-ray scattering in the small-angle portion and a broad peak is observed in the vicinity of the scattering vector q = 0.1 to 0.5 nm ⁻¹ , it is a micellar phase.

In addition, it is preferable that a skin cleansing composition is transparent from the beauty of appearance etc. Note that “transparent” means “「 ”and“ ◯ ”in the evaluation criteria in the measurement of <Transparency> in Examples described later. In the measurement of <Transparency> in Examples described later, in order to obtain a “transparent” composition having a transparency of ◎, the components (A) to (D) preferably satisfy the following conditions.
The content of the component (A) is 20 to 35% by mass in the skin cleanser composition, and the mass ratio of the higher fatty acid salt having 12 or less carbon atoms and the higher fatty acid salt having 14 or more carbon atoms is 80/20 to 50/50.
Component (B) is lauryldimethylaminoacetic acid betaine, and its content is 7 to 15% by mass in the skin cleanser composition.
Component (C) consists of PEG-20 glyceryl triisostearate, PEG-20 glyceryl trioleate, PEG-20 trimethylolpropane triisostearate, POE (20-80) hydrogenated castor oil and POE (20-80) castor oil The content thereof is 2 to 5% by mass in the skin cleanser composition.
Component (D) is a combination of propylene glycol and glycerin, propylene glycol or polyethylene glycol 400, and its content is 25 to 35% by mass in the skin cleanser composition. When propylene glycol and glycerin are used in combination Has a propylene glycol ratio of 20/80 or more.

In the skin cleansing composition of the present invention, other appropriately selected components can be blended within a range that does not interfere with the object of the present invention. Other components can be appropriately selected from those commonly used in skin cleanser compositions, such as oils, silicones, alcohols such as lower or higher alcohols, lanolin derivatives, protein derivatives, acrylic resins. Dispersions, drugs such as vitamins, bactericides, antiseptics, pH adjusters such as potassium hydroxide and citric acid, antioxidants, sequestering agents, UV absorbers, animal and plant extracts or their derivatives, dyes, fragrances, pigments And water-insoluble polymer powder such as inorganic powder, clay mineral, nylon and polyethylene.

The pH of the skin cleansing composition of the present invention is preferably 9.0 to 11.0 from the viewpoint of low temperature stability and liquid crystal formation, and more preferably 9.4 to 10.6 from the viewpoint of low temperature stability. . When the pH is less than 9.0, the low-temperature stability may deteriorate, and when it exceeds 11.0, it may be difficult to form a liquid crystal.

The viscosity of the skin cleanser composition of the present invention is preferably 20 to 500 Pa · s at 25 ° C., more preferably 130 to 350 Pa · s. If it is less than 20 Pa · s, the high-temperature stability may be deteriorated, and if it exceeds 500 Pa · s, the solubility of the preparation in water may be deteriorated. The viscosity was measured using a BH type viscometer (manufactured by Tokyo Keiki Co., Ltd.) at a sample temperature of 25 ° C. 7. Measure the viscosity after 1 minute at 4 rpm.

The skin cleansing composition of the present invention may be used for both face and body, and the target is not particularly limited as long as it is skin.

Hereinafter, although an Example and a comparative example are shown and this invention is demonstrated concretely, this invention is not restrict | limited to the following Example. In the following examples, unless otherwise specified, “%” in the composition indicates mass%, the ratio indicates the mass ratio, and the amount of each component in the table is an amount converted into a pure component.

[Examples 1 to 38, Comparative Examples 1 to 12]
A skin cleanser composition was prepared as follows. Components (A), (C), (D) and purified water were weighed into a vessel of a vacuum emulsification kettle. Under reduced pressure, it was heated to 80 ° C. to dissolve. After dissolution, the component (B) was added and dissolved while stirring the paddle, cooled to 35 ° C. at 1 ° C./min in a reduced pressure state, and sufficiently depressurized and stirred for deaeration. After deaeration, cooling was performed to 25 ° C. at 1 ° C./min. Subsequently, the pH was measured using a pH meter HM-30R (manufactured by Toa DKK Co., Ltd.), and the target pH was set using potassium hydroxide or citric acid. The pH was measured after the electrode was immersed in a sample at 25 ° C. for 2 minutes. The following evaluation was performed about the obtained skin cleaning composition. The results are also shown in the table.

<viscosity>
Using a BH type viscometer (manufactured by Tokyo Keiki Co., Ltd.), the sample temperature was 25 ° C. and the rotor No. 7. Viscosity after 1 minute at 4 rpm was measured.

<Checking the LCD status>
The confirmation of the liquid crystal state was carried out using a polarizing microscope AX70 (Olympus Corporation) with the skin cleansing composition at 25 ° C. When the interference pattern was observed as a scaly mosaic texture, it was a hexagonal liquid crystal, when a cross-shaped cross Nicol was observed, it was a lamellar liquid crystal, and when no interference pattern was observed, it was a micelle phase. The liquid crystal of the present invention refers to hexagonal liquid crystal, lamellar liquid crystal, and cubic liquid crystal. These typical interference patterns are exemplified in RBRosevere, “The microscopy of the Liquid Crystalline Neat and Middle Phase of soaps and synthetic detergents” J. Am. Oil Chemist's Soc., 628, 31 (1954). In addition, when dispersion | distribution of the solid substance was seen at 25 degreeC, even if these interference patterns were seen, it was not judged as a liquid crystal phase.
On the other hand, if it is difficult to determine a cubic liquid crystal layer that is very viscous and has no interference pattern, or if it is difficult to determine with a polarizing microscope, an X-ray diffractometer X 'Pert Pro with a small-angle light receiving unit and an X-ray condenser mirror (PANalitical) was used to determine from the X-ray scattering interference pattern in the small-angle part. Corresponding to the (100), (110), (200) planes, a hexagonal liquid crystal phase having a peak at a scattering angle corresponding to the inter-plane distance ratio of 1: √3: 2:... (100) , (200), (300) corresponding to the plane spacing ratio of 1: 2: 3:..., Lamellar liquid crystal, (100), (111), (200 ) 1: √3 / 2 corresponding to the surface spacing of the surfaces: √2:..., And 1: √4 / 3 corresponding to the (211), (220), (321), (400) surfaces: A liquid crystal having a peak at √7 / 3: √8 / 3:. In addition, when no clear peak was observed in the x-ray scattering in the small-angle portion and a broad peak was observed in the vicinity of the scattering vector q = 0.1 to 0.5 nm ⁻¹ , the micelle phase was set. The following symbols are used in the table.
Lamella liquid crystal: L
Cubic layer: C
Hexagonal liquid crystal: H
Micelle: M
Solid dispersion: S

<High temperature / low temperature stability>
A hard transparent glass bottle (capacity 55 mL) with a height of 8 cm and a diameter of 3 cm is filled with 50 mL of the skin cleansing composition, stored in each environment at 50 ° C. and 0 ° C., observed for appearance at each storage temperature, and judged as follows: Based on the criteria, the stability of the skin cleanser composition was evaluated.
[Judgment criteria]
A: After storage for 4 weeks, it is transparent and uniform with no phase separation or precipitates.
A to B: After storage for 4 weeks, there is no phase separation or precipitate, but a part of the appearance looks slightly cloudy.
○: After storage for 4 weeks, there is no phase separation or precipitates, but the appearance appears to be uniformly and slightly turbid.
Δ: No phase separation or precipitates after storage for 2 weeks, but phase separation or precipitates after storage for 4 weeks.
X: After storage for 2 weeks, there is phase separation or precipitate.

<Transparency>
A hard transparent glass bottle (capacity 55 mL) having a height of 8 cm and a diameter of 3 cm was filled with 50 mL (6 cm in height) of the skin cleansing composition and stored in an environment at 25 ° C. for one day. The above glass bottle filled with each sample is placed on a paper printed with MS Gothic "A", and the skin cleansing composition is based on the following criteria for the discrimination of characters printed on the paper from the top of the glass bottle The transparency of was evaluated.
[Judgment criteria]
A: “A” printed with 20 points of MS Gothic body can be clearly identified.
○: “A” printed with 20 points of MS Gothic font appears blurry but can be distinguished.
Δ: “A” printed with 20 points of MS Gothic cannot be discriminated, but “A” printed with 24 points can be discriminated.
X: “A” printed with 24 points of MS Gothic cannot be identified.

<Ease of melting during use>
The ease of dissolution of the skin cleanser composition during use was evaluated by 10 professional evaluation panels using the skin cleanser composition. A tube container (3 cm in diameter, 8 cm in height, 5 mm in diameter) was filled with the skin cleanser composition, 1 g of each sample was taken into the palm wetted with water, and foamed by extending with both hands, and the ease of melting was evaluated. Evaluation was made based on the following criteria based on the following criteria based on the five-point score based on the following criteria.
[Judgment criteria]
5 points: At the same time as rubbing the palm, the sample melts and foams.
4 points: The sample melts and foams 2 to 3 times after rubbing the palm.
3 points: The sample melts and foams 4 to 7 times after rubbing the palm.
2 points: Starting to rub the palm, the sample melts and bubbles in 8-12 times.
1 point: The sample agent slides down from the hand, or the sample adheres to the palm or finger, and even if the palm is rubbed 13 times or more, foaming cannot be made.
[Standard of average score]
◎: 4.5 to 5 points ◎ to ○: 4.0 points to less than 4.5 points ○: 3.0 points to less than 4.0 points Δ: 2.0 points to less than 3.0 points ×: 2 Less than 0 points

In addition, in order to confirm the bactericidal power of the skin cleansing composition of the present invention, the following bactericidal power tests were conducted on Examples 1 and 36.
<Bactericidal power>
(1) Preparation of Bacterial Solution A bacterial solution was prepared so that the initial number of the following bacteria was 10 8 / mL.
Staphylococcus aureus: Staphylococcus aureus ATCC 6538
(2) Test solution The skin cleanser composition obtained in Examples 1 and 36 was diluted 5-fold with tap water to prepare a test solution.
<Sterilizing power test method>
At 25 ° C., 1 mL of the bacterial solution was added to 9 mL of the test solution and stirred sufficiently. One minute after the addition, 4.5 mL of SCDLP medium (Soybean-Casein Broth with Lectin & Polysorbate 80: manufactured by Wako Pure Chemical Industries, Ltd.) In addition, a 10-fold diluted solution was obtained. The same method was repeated to obtain each diluted solution. Collect 1.0 mL from each diluted solution in a petri dish, add 15 mL of SCDLP agar medium (Soybean-Casein Digest Age with Lectin & Polysorbate 80: manufactured by Wako Pure Chemical Industries, Ltd.), homogenize, and culture for 2 days (agar plate dilution) Method), colonies were counted and the number of viable bacteria was measured. Based on the following formula, bactericidal power was calculated from the initial bacterial count and viable bacterial count, and the bactericidal effect was evaluated according to the following evaluation criteria.
Bactericidal power = log (number of viable bacteria / number of initial bacteria)
In addition, the effect is so high that a sterilization power is small.

The bactericidal power of Example 1 is “−1.1”, the bactericidal power of Example 36 is “−3.2”, and the bactericidal power is improved by using a monoethanolamine salt as the component (A). Was confirmed. Further, Example 36 was “低温” even at low temperature stability (−5 ° C., 1 month), and was excellent in low temperature stability.

[Example 39]
A skin cleanser composition was prepared as follows. Common components other than lauryldimethylaminoacetic acid betaine and flavor were weighed in a vessel of a vacuum emulsification kettle. Under reduced pressure, it was heated to 80 ° C. to dissolve. After dissolution, while stirring the paddle, lauryldimethylaminoacetic acid betaine was added and dissolved, and the mixture was cooled to 35 ° C. at 1 ° C./min under reduced pressure. At this time, degassing was performed by sufficiently reducing pressure and stirring. After deaeration, a fragrance was added and cooled to 25 ° C. at 1 ° C./min. Subsequently, the pH was measured using a pH meter HM-30R (manufactured by Toa DKK Co., Ltd.), and the target pH was set using potassium hydroxide or citric acid.
Composition%
Potassium laurate 21
Potassium myristate 9
Lauryldimethylaminoacetic acid betaine * 1 9
Polyoxyethylene hydrogenated castor oil (E.O.20) * 10 3
Propylene glycol 9
Glycerin 21
Isopropyl methylphenol * 19 0.1
Monoethanolamine 0.5
Edetic acid 0.1
Vitamin E * 20 0.1
Polyethylene powder * 21 0.3
Fragrance 0.4
Purified water balance 100.0
The pH was adjusted to 10.2 with potassium hydroxide (48%) or citric acid.
<Evaluation results>
Viscosity: 118 Pa · s
Transparency: ◎
Crystal phase: H
Stability (50 ° C): ◎
Stability (0 ° C): ◎
Stability (-5 ° C): ◎

The raw materials used in preparing the examples and comparative examples are shown below.
* 1: Amorgen SH (Daiichi Kogyo Seiyaku)
* 2: Ammogen SH is taken in a stainless steel vat, dried with a vacuum dryer (40 ° C), and the pure content is concentrated to 80%.
* 3: LPB-R (one company oil industry)
* 4: EMALEX GWIS-320 (Japan Emulsion, HLB = 8)
* 5: GWS-320 (Japan emulsion, HLB = 8)
* 6: GWO-320 (Japan emulsion, HLB = 8)
* 7: TPIS-320 (Japan emulsion, HLB = 8)
* 8: C-20 (Japan emulsion, HLB = 9)
* 9: HC-10 (Japan emulsion, HLB = 7)
* 10: HC-20 (Japan emulsion, HLB = 9)
* 11: HC-40 (Japan emulsion, HLB = 12)
* 12: HC-80 (Japan emulsion, HLB = 15)
* 13: PEG # 400K (Lion)
* 14: NEOSORB70 / 02SB (Rocket Japan)
* 15: HC-5 (Japan emulsion, HLB = 5)
* 16: HC-100 (Japan emulsion, HLB = 15)
* 17: GWIS-220EX (Japan emulsion, HLB = 10)
* 18: GWIS-120 (Japan emulsion, HLB = 13)
* 19: IPMP (Osaka Kasei)
* 20: dl-α Tocopherol (DSM Nutrition Japan)
* 21: Flow beads CL-8007 (Sumitomo Seika)
* 22: Concentrated glycerin for cosmetics

Claims

A skin cleanser composition containing the following components (A), (B), (C) and (D) and in a liquid crystal state at 25 ° C.
(A) 15 to 45% by mass of higher fatty acid salt having 8 to 26 carbon atoms
(B) Betaine amphoteric surfactant 7 to 25% by mass
(C) 1 to 5% by mass of the following nonionic surfactant
Three hydroxyl groups of polyoxyethylene (average added mole number of ethylene oxide 10 to 80) glyceryl, glycerin, or polyoxyethylene (average added mole number of ethylene oxide 10 to 80) trimethylolpropane are esterified or etherified. The esterified or etherified moiety is a saturated or unsaturated, linear or branched monovalent hydrocarbon group having 7 to 25 carbon atoms, and part of the hydrogen atoms are substituted with hydroxyl groups. The polyoxyethylene having an average addition mole number of 10 to 80 may be added to this hydroxyl group, provided that the total number of polyoxyethylene added to the nonionic surfactant is the average addition mole number. 10 to 80.
(D) 15 to 35% by mass of polyhydric alcohol
The skin cleanser according to claim 1, wherein the component (C) is a monovalent hydrocarbon group having 7 to 25 carbon atoms in the esterified or etherified moiety, wherein a part of the hydrogen atoms is substituted with a hydroxyl group. Agent composition.
The skin cleansing composition according to claim 1 or 2, wherein the component (C) is polyoxyethylene hydrogenated castor oil or polyoxyethylene castor oil.
4. The skin cleanser composition according to claim 1, 2 or 3, wherein the liquid crystal is hexagonal liquid crystal.