WO2012028965A3 - Combination of semax and choline alfoscerate with antihypoxic neuroprotective, and antiαμνesic action and with ability to improve physical efficiency - Google Patents

Combination of semax and choline alfoscerate with antihypoxic neuroprotective, and antiαμνesic action and with ability to improve physical efficiency Download PDF

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Publication number
WO2012028965A3
WO2012028965A3 PCT/IB2011/002779 IB2011002779W WO2012028965A3 WO 2012028965 A3 WO2012028965 A3 WO 2012028965A3 IB 2011002779 W IB2011002779 W IB 2011002779W WO 2012028965 A3 WO2012028965 A3 WO 2012028965A3
Authority
WO
WIPO (PCT)
Prior art keywords
action
antihypoxic
ability
neuroprotective
physical efficiency
Prior art date
Application number
PCT/IB2011/002779
Other languages
French (fr)
Russian (ru)
Other versions
WO2012028965A2 (en
Inventor
Владимир Викторович ЯСНЕЦОВ
Юрий Викторович ИВАНОВ
Виктор Владимирович ЯСНЕЦОВ
Михаил Владимирович ОВЧИННИКОВ
Евгений Александрович ЧЕРТОРИЖСКИЙ
Елена Витальевна КУДРЯВЦЕВА
Original Assignee
Градстейн Инвестментс Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Градстейн Инвестментс Лимитед filed Critical Градстейн Инвестментс Лимитед
Priority to UAA201303190A priority Critical patent/UA107603C2/en
Priority to EA201300248A priority patent/EA020948B1/en
Publication of WO2012028965A2 publication Critical patent/WO2012028965A2/en
Publication of WO2012028965A3 publication Critical patent/WO2012028965A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

This invention relates to medicines, in particular, to pharmaceutical compositions which have an antihypoxic, neuroprotective, and antiamnesic action and an ability to improve physical efficiency and which are also used to treat acute and chronic cerebral-circulation disorders, including ischemic stroke and other diseases and conditions accompanied by a lower cognitive function. This pharmaceutical composition contains such active ingredients as Semax and choline alfoscerate at a ratio between 1 : 50 and 1: 8,000 (w/w), respectively, as well as pharmaceutically acceptable excipients. This invention solves such a problem as a product range extension for simple-composition drug products with a strong neuroprotective action accompanied by an antihypoxic and antiamnesic action and by an ability to improve physical efficiency.
PCT/IB2011/002779 2010-08-16 2011-08-12 Pharmaceutical composition with antihypoxic neuroprotective, and antiamnesic action and with ability to improve physical efficiency WO2012028965A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
UAA201303190A UA107603C2 (en) 2010-08-16 2011-08-12 Composition of semaks and choline alfoz oilcloth having antihypoxic, neuroprotective and anti-amnesic activity and improves physical performance
EA201300248A EA020948B1 (en) 2010-08-16 2011-08-12 Pharmaceutical composition with antihypoxic, neuroprotective and antiamnesic action and with ability to improve physical efficiency

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2010133893 2010-08-16
RU2010133893/15A RU2425670C1 (en) 2010-08-16 2010-08-16 Pharmaceutic composition, possessing antihypoxic, neuroprotective and antiamnestic activity and increasing physical performance capacity

Publications (2)

Publication Number Publication Date
WO2012028965A2 WO2012028965A2 (en) 2012-03-08
WO2012028965A3 true WO2012028965A3 (en) 2012-08-16

Family

ID=44754442

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2011/002779 WO2012028965A2 (en) 2010-08-16 2011-08-12 Pharmaceutical composition with antihypoxic neuroprotective, and antiamnesic action and with ability to improve physical efficiency

Country Status (4)

Country Link
EA (1) EA020948B1 (en)
RU (1) RU2425670C1 (en)
UA (1) UA107603C2 (en)
WO (1) WO2012028965A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2480233C1 (en) * 2012-02-29 2013-04-27 Замертон Холдингс Лимитед Pharmaceutical composition possessing antihypoxic, neuroprotective and antiamnestic activity
RU2547090C2 (en) * 2013-01-16 2015-04-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный государственный университет физической культуры, спорта и здоровья имени П.Ф. Лесгафта, Санкт-Петербург" Method for correction of individual's functional state and performance
RU2564008C2 (en) * 2013-09-26 2015-09-27 Закрытое акционерное общество "ЭкоФармПлюс" Pharmaceutical composition, possessing antihypoxic, neuroprotective and antiamnestic activity, increasing physical workability
RU2750418C1 (en) * 2020-11-20 2021-06-28 Виктор Владимирович Яснецов Drug with antihypoxic, antiamnestic and neuroprotective activity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2435605C1 (en) * 2010-11-12 2011-12-10 Сагидуллин Диаз Факилович Ergogenic pharmaceutical composition exhibiting antihpoxic, neuroprotective and antiamnestic activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2251429C2 (en) 2002-12-30 2005-05-10 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Pharmaceutical composition for treating ischemic insult and method for therapy
RU2280428C1 (en) 2004-12-20 2006-07-27 Петр Васильевич Ипатов First aid emergency kit used at acute disorder of cerebral circulation of the blood
RU2385722C1 (en) 2008-07-02 2010-04-10 Тимофей Георгиевич Кожока Pharmaceutical neuroprotective, antioxidant, antihypoxic, antiapoptotic and membrane protective composition and method of treatment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2435605C1 (en) * 2010-11-12 2011-12-10 Сагидуллин Диаз Факилович Ergogenic pharmaceutical composition exhibiting antihpoxic, neuroprotective and antiamnestic activity

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 12 December 2011 (2011-12-12), YASNETSOV, V. V.: "Pharmaceutical composition with antihypoxic, neuroprotective and antiamnestic activity and stimulating effect on physical capacity", XP002672388, retrieved from STN Database accession no. 2011:1597993 *
DOLOTOV OLEG V ET AL: "Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain", JOURNAL OF NEUROCHEMISTRY, vol. 97, no. Suppl. 1, April 2006 (2006-04-01), pages 82 - 86, XP008150232, ISSN: 0022-3042 *
ONISHCHENKO L S ET AL: "Changes at the focus of experimental ischemic stroke treated with neuroprotective agents", NEUROSCIENCE AND BEHAVIORAL PHYSIOLOGY, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 38, no. 1, 1 January 2008 (2008-01-01), pages 49 - 54, XP019578944, ISSN: 1573-899X *

Also Published As

Publication number Publication date
RU2425670C1 (en) 2011-08-10
EA020948B1 (en) 2015-02-27
EA201300248A1 (en) 2013-06-28
UA107603C2 (en) 2015-01-26
WO2012028965A2 (en) 2012-03-08

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