WO2012026645A1 - Procédé de traitement et de prévention du virus du couvain sacciforme - Google Patents

Procédé de traitement et de prévention du virus du couvain sacciforme Download PDF

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Publication number
WO2012026645A1
WO2012026645A1 PCT/KR2010/006278 KR2010006278W WO2012026645A1 WO 2012026645 A1 WO2012026645 A1 WO 2012026645A1 KR 2010006278 W KR2010006278 W KR 2010006278W WO 2012026645 A1 WO2012026645 A1 WO 2012026645A1
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WO
WIPO (PCT)
Prior art keywords
goat
ginseng
sugar
liquid
water
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PCT/KR2010/006278
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English (en)
Korean (ko)
Inventor
정형범
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Jung Hyeong Beom
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Publication date
Application filed by Jung Hyeong Beom filed Critical Jung Hyeong Beom
Publication of WO2012026645A1 publication Critical patent/WO2012026645A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Definitions

  • the present invention relates to a method for treating and preventing Tobong virus worms.
  • Goat's ginseng is obtained by cultivating wild ginseng, which has been known to have similar efficacy.
  • the main roles of saponins medically revealed in Healthweek include Rb1-Liver Function Recovery / Fatigue Recovery, Rb2-Diabetes Control / Obesity and Atherosclerosis / Liver Proliferation, Rh1-Liver Function Improvement / Fatigue Restoration / platelet coagulation inhibition, Rh2-anticancer and immunity enhancement, Rg1-memory and dementia prevention / diabetes control / obesity prevention / fatigue prevention, Rg2-memory prevention and platelet coagulation inhibition, Rg3-anticancer and anticancer resistance / Immuno-enhancing, Re-Liver Protection / Promoting Bone Marrow Cell Production / Strengthening Memory and Preventing Dementia, Other Rf, Ro, Rd, etc.Let Lipid Peroxidation / Cerebral Nerve Cell Analgesic / Alcohol Detoxification, In
  • worms are caused by malnutrition of bees caused by the recent disappearance of flowers.
  • Tobong farmers are in serious danger due to the infection of “worm bugs” and the Ministry of Food, Agriculture, Forestry and Fisheries and the National Veterinary Research and Quarantine Service have mobilized their own methods, but they have yet to find a clear treatment.
  • the content of advertisements related to ginseng, tissue culture ginseng, red ginseng and other ginsengs is based on the degree of inclusion of ginsenosides and scafponins. This proves that the role of saponin in ginseng and the like is great, and in the process of discovering this, the applicant has confirmed that the superior mountain ginseng has more saponin content and types in Korea.
  • the better mountain ginseng is “sweeter and stronger in scent,” which is the word that has been handed down in the oral and ancient books, and the fact that wild ginseng is higher in sugar than any other fruits such as watermelon, strawberry, tangerine, and saponin is higher.
  • wild ginseng is higher in sugar than any other fruits such as watermelon, strawberry, tangerine, and saponin is higher.
  • saponin and sugar content is proportional to the world for the first time, it was intended to apply to the present invention.
  • the inventors of the present invention the higher the sugar content of the goat ginseng contains a large amount of saponin, and the saponins have a high antimicrobial and antiviral effect, and tried to apply it to the treatment and prevention of bees infected with cystitis rot disease.
  • an object of the present invention is to provide a method for the treatment and prevention of viral worms.
  • the method for treating and preventing viral nematode buds rot of the present invention is mixed with goat ginseng and water in a weight ratio of 1: 1 to 2 to obtain a goat goat extract in a vacuum condition at low temperature, and then concentrated goat goat concentrate
  • a step preparing a liquid goat ginseng adjusted to have a sugar content of at least 45BRIX by mixing the goat goat concentrate with water, and diluting the liquid goat ginseng is fed to bees infected or not infected with viral worms Characterized in that it comprises a step.
  • the salary for the bees infected with the worm beetle rot disease was diluted in a ratio of 1 g of goat's ginseng and 250 to 300 ml of water, and prepared liquid goat ginseng adjusted to sugar with sugar and then fed at a rate of 400 to 600 ml of liquid goat ginseng per beehive
  • the treatment of 20 times a day once a treatment to treat is a healthy goat ginseng diluted by 1.5 g of goat ginseng concentrate and 250 to 300 ml of water and adjusted to sugar with sugar
  • goats ginseng and water 1: 1 to 2 by weight ratio by mixing the goats ginseng extract obtained under a low-temperature vacuum condition and then concentrated 1.0 to 1.5 g and water 250 obtained It is characterized by a cystic rodents rot disease treatment and prevention agent comprising a liquid goat ginseng adjusted to a sugar content of at least 45BRIX by mixing at a ratio of 300 to 300ml.
  • the goat ginseng is mixed with a small amount of water to obtain a concentrate by vacuum extraction at low temperature.
  • the concentrate is obtained in this way, it is possible to obtain a goat goat concentrate that reflects the pharmacological effects of goat goat.
  • Ginseng, fresh ginseng, white ginseng, red ginseng can be used instead of goat ginseng, and it is possible to obtain a concentrate with sufficient pharmacological effects such as ginseng even if it is not possible to obtain a concentrate with sufficient saponin content as that of goat ginseng. .
  • the wild ginseng culture root will be able to obtain a similar effect to the wild ginseng, it would be possible to apply a wild ginseng culture root instead of a goat.
  • goats harvested in early May to the end of August can use both roots and shoots and leaves of goats Goat ginseng, which is harvested from early September to late April, should be rooted.
  • the cultivation period is more than 7 years, and if necessary, the cultivation period is less than this, but it is preferable to use 7 years old rooted for 7 years.
  • goats and water are mixed in a ratio of 1: 1 to 2, preferably 1: 1.
  • a goat goat extract is concentrated in a short time under low temperature vacuum conditions.
  • the extraction of the goat is made in a vacuum, it is preferable that the goat is made at a low temperature in the range of 50 to 90 °C in terms of protection of the active ingredient of goat.
  • Goat ginseng extract extracted under the vacuum condition of the low temperature is concentrated under vacuum conditions to obtain a goat goat concentrate.
  • the extraction and concentration of the goat goat is made in a short period of time within 30 minutes to 2 hours.
  • the concentrated goat goat extract is prepared in liquid form to feed the bees to the bees.
  • the goat goat concentrate is mixed with water.
  • the goat ginseng concentrate is mixed with water to adjust the sugar content to at least 45BRIX. If the sugar content is too low it may contain additional sugar. Goat ginseng is higher in sugar than ordinary ginseng, and thus, the above sweetness is easily achieved. In addition, if the sugar is less than the above range, the bees will not easily eat, it is preferable to adjust the sugar to the above range.
  • the wild ginseng discarded the preconceived notation that saponin will be used, and by the phrase "the better goat is stronger and sweeter", it was confirmed that the sugar content of goat ginseng was proportional to the saponin content. It is desirable to adjust the above range because it may not be fed to the food.
  • the liquid goat ginseng is diluted to feed to bees infected with or not infected with virus worms.
  • the feed for bees infected with worms is 1% goat ginseng concentrate in a ratio of 250 to 300 ml of water, preferably 290 ml of water.
  • the liquid goat ginseng per beehive 400 to 600ml ratio preferably in a liquid goat ginseng 500ml per one beehive, but 20 salary twice a day Treat it.
  • honeybees infected with cystic beetle rot return to immunity and complete prevention, and produce honey normally.
  • the feed for honeybees infected with the cystic rodent rot is diluted 1.5 g of goat ginseng concentrate in a ratio of 250 to 300 ml of water, preferably 290 ml of water, and sugar content in sugar.
  • a liquid goat ginseng adjusted to control the amount of liquid goat ginseng 400 to 600ml per beehive, preferably in a ratio of 500 ml of liquid goat ginseng per beehive, it is preferable to prevent it by feeding once every two days.
  • goat and ginseng are mixed at a weight ratio of 1: 1 to 2 to obtain a goat goat extract under a low temperature vacuum condition, and then concentrated at 1.0-1.5 g of a goat goat concentrate obtained by concentrating with water at a ratio of 250 to 300 ml to have a sugar content of at least 45 BRIX.
  • Controlled liquid goat ginseng is sufficient as a treatment or prevention of cystic rodent rot.
  • FIG. 1 is a photograph of a process of injecting a liquid goat ginseng prepared by the present invention into the body as a bee food.
  • Figure 2 is a photograph of a bee infected with virus worms rot.
  • FIG. 3 is a photograph of a bee treated with viral worms.
  • Example 1 1 g of goat's ginseng concentrate obtained in Example 1 was mixed with 290 ml of bottled water, and sugar was prepared by mixing until the sugar content of 45BRIX was suitable as a food for bees to prepare a liquid goat.
  • Feeding amount was adjusted to 500ml of liquid goat ginseng per beehive. After 15 days of salary, about 1 kg of goat ginseng honey was obtained from a single beehive.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La présente invention concerne un procédé pour traiter et prévenir le virus du couvain sacciforme, et plus particulièrement, un procédé pour traiter et prévenir le virus du couvain sacciforme comprenant les étapes suivantes : mélange de ginseng sauvage et d'eau à un rapport en poids de 1:1-2 pour obtenir un extrait de ginseng sauvage à basse température et dans un état sous vide, et concentration de celui-ci ; mélange du concentré de ginseng sauvage avec de l'eau pour fabriquer du ginseng sauvage liquide ayant une teneur en glucides d'au moins 45 Brix ; et dilution et fourniture du ginseng sauvage liquide à des abeilles qui ont ou n'ont pas contracté le virus du couvain sacciforme. Selon la présente invention, le virus du couvain sacciforme peut être efficacement traité ou prévenu chez Apis cerena ou Apis mellifera.
PCT/KR2010/006278 2010-08-27 2010-09-14 Procédé de traitement et de prévention du virus du couvain sacciforme WO2012026645A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20100083358 2010-08-27
KR10-2010-0083358 2010-08-27

Publications (1)

Publication Number Publication Date
WO2012026645A1 true WO2012026645A1 (fr) 2012-03-01

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Family Applications (1)

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PCT/KR2010/006278 WO2012026645A1 (fr) 2010-08-27 2010-09-14 Procédé de traitement et de prévention du virus du couvain sacciforme

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040016112A (ko) * 2002-08-16 2004-02-21 윤희경 인삼성분이 함유된 토종꿀 및 양봉꿀을 얻는 방법 및그로부터 얻어진 꿀
KR100727435B1 (ko) * 2006-07-05 2007-06-13 천지영농조합법인 산양삼 고 제조방법과 산양삼 고

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040016112A (ko) * 2002-08-16 2004-02-21 윤희경 인삼성분이 함유된 토종꿀 및 양봉꿀을 얻는 방법 및그로부터 얻어진 꿀
KR100727435B1 (ko) * 2006-07-05 2007-06-13 천지영농조합법인 산양삼 고 제조방법과 산양삼 고

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Eradication method for Sacbrood", ARTICLE OF YONHAPNEWS, 19 August 2010 (2010-08-19) *

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