WO2011141688A1 - Paquet pour système de dosage surveillé - Google Patents
Paquet pour système de dosage surveillé Download PDFInfo
- Publication number
- WO2011141688A1 WO2011141688A1 PCT/GB2011/000680 GB2011000680W WO2011141688A1 WO 2011141688 A1 WO2011141688 A1 WO 2011141688A1 GB 2011000680 W GB2011000680 W GB 2011000680W WO 2011141688 A1 WO2011141688 A1 WO 2011141688A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- flexible lamina
- pack
- lamina
- blister
- flexible
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
- B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
- B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2585/00—Containers, packaging elements or packages specially adapted for particular articles or materials
- B65D2585/56—Containers, packaging elements or packages specially adapted for particular articles or materials for medicinal tablets or pills
Definitions
- This invention relates to dispensing packs for blister-packed items. Specifically, this invention relates to monitored dosage system packs for receiving and dispensing pharmaceuticals without the need for prior de-blistering.
- MDS Patient monitored dosage system packs
- a conventional MDS pack is shown in Figures 1 and 2.
- the MDS pack 100 comprises an upper card sheet 101 sealed to a lower card sheet 102. Between the upper card sheet 101 and the lower card sheet 102 is frangible foil layer 103.
- the MDS pack 100 also includes an array of deformable raised window segments 104 providing a cavity for the storage of pharmaceutical capsules 105, tablets etc.
- the MDS packs 100 are pre-loaded with de-blistered pharmaceuticals by a dispensing chemist. Each capsule 105 must be manually removed from the manufactures supplied blister packs and placed in the appropriate window cavity prior to hot or cold sealing of the MDS pack foil layer. Once pre-loaded and sealed, the MDS pack can be supplied to the end-user.
- the heat-sealing process may adversely affect the efficacy of some heat- sensitive medicines and the cold seal process may not protect sufficiently from moisture ingress.
- FIG. 3 Another conventional dispensing package is described in EP-A-0 189 276.
- a hinged book-shaped cover 200 is provided with a series of openings 201 for receiving and holding in place a complete blister pack.
- the cover 200 includes a plurality of press fasteners arranged around the periphery [not shown] of the cover to enable the cover to be folded and fastened together.
- the cover 200 is constructed from a stiff plastics material.
- a dispensing pack comprising a first flexible lamina and a second flexible lamina; the first flexible lamina includes a first array of apertures, and the second flexible lamina includes a second array of apertures and an adhesive layer exposable by a removable protective sheet; wherein the first flexible lamina and second flexible lamina are adapted to be mated via removal of the protective sheet and exposure of the adhesive layer such that the first array and second array of apertures correspond in alignment.
- the first flexible lamina and the second flexible lamina are fabricated from a polypropylene-based synthetic paper.
- the synthetic paper is YUPO ⁇ .
- a method of providing a dispensing pack including a plurality of sealed items including: providing a dispensing pack as described in claim 1 ; dividing a blister pack containing a plurality of individually sealed items into individual separated blister elements; placing each individual separated blister element into an aperture of the first flexible lamina such that a blister pocket of each individual separated blister element protrudes through the aperture; removing the protective sheet from the second flexible lamina to expose the adhesive layer; bringing the second flexible lamina into alignment and contact with the first flexible lamina such that the first lamina adhesively mates with the second flexible lamina and holds each of the individual blister elements securely in place.
- An advantage of this method is that the manufacturer's shelf-life guarantee is retained since the pharmaceutical remains in its original packaging, and any contamination is avoided. Also, no hot or cold sealing of the pack is required. Also, the cost and time of deblistering with its attendant disadvantages and possible dangers is avoided.
- this invention can be applied to the re-packaging or distribution of any product where it is desirable to present, display or dispense the product without removing the product from the manufacturer's blister pack.
- Figure 1 shows a conventional MDS pack
- Figure 2 shows a cross-sectional view of the MDS pack of Figure 1 ;
- Figure 3 shows a plan view of a prior art dispensing cover;
- Figures 4A to 4C show a dispensing operation of the MDS pack of Figure 1 ;
- Figure 5 shows an embodiment of a dispensing pack of the present invention
- Figure 6 shows an alternative embodiment of a dispensing package of the present invention
- Figure 7A shows a conventional pharmaceutical blister pack
- Figure 7B shows a cross-sectional view of the blister pack of Figure 7 A
- Figures 8A to 8D show pre-loading and dispensing operations of a dispensing package of the present invention.
- Figures 4A to 4C show a cross-sectional view of the prior art MDS pack 100 shown in Figure 1.
- a de-blistered pharmaceutical capsule 105 is held within a deformable transparent pocket 106.
- Downward finger pressure 107 deforms the pocket 106 and the capsule 105 is forced downwards 108 through the frangible foil layer 103 and is dispensed.
- Figures 5 and 6 show alternative embodiments of a dispensing pack 1 of the present invention.
- the pack 1 comprises a front lamina 2 and a rear lamina 3.
- Figure 5 shows an example of a dispensing pack having separate front and rear laminae
- Figure 6 shows an alternative pack wherein the front and rear laminae are joined via a fold line.
- the dispensing pack 1 includes rows and columns of apertures 4. For clarity, only the front lamina 2 is shown with an aperture matrix. It will be clear however, that a corresponding aperture matrix also exists on the rear lamina 3.
- the dispensing pack 1 includes mounting holes 6 through which the rings of a ring-binder or a pair of parallel hanging bars can be passed.
- the dispensing pack 1 is preferably manufactured from a synthetic paper such as YUPO ⁇ which is polypropylene-based synthetic paper. Such synthetic paper can be readily printed upon, is light, flexible and provides adequate strength such that a user cannot inadvertently tear or damage the pack during a dispensing operation. Most pharmaceuticals are provided by the manufacturer in a blister pack 20 as shown in Figure 7A. Blister packs are well known so no detailed description of their form or function is required here.
- the blister pack 20 is divided along the broken lines 21, 22 into individual blister elements 24 by a suitable cutting operation.
- the cutting operation may be manual or achieved using an appropriate cutting machine.
- Figure 7B shows the direction and position of the cutting planes for the desired separation of individual blister elements 24.
- the original blister pack 20 may be supplied pre- perforated along the broken lines to facilitate easier separation.
- each individual blister element 24 produced by the aforementioned cutting operation is positioned in alignment with an aperture 4 of the front lamina 1 [it should be noted that in practice the front lamina would be orientated upside down so that the blister elements would be held in the apertures by gravity].
- protective sheet 9 is removed to reveai and adhesive layer on the rear lamina 2 [ Figure 8B].
- the adhesive layer (not shown] has been exposed by removal of the protective sheet 9. the rear lamina 2 can be brought into contact with the front lamina 1 and the two laminae will be bonded to one another securing all the individual blister elements 24 in place, with the front and rear apertures in alignment [Figure 8C].
- Unused pharmaceuticals can be recovered by soaking or wetting a returned dispensing pack with a suitable release agent to neutralises the adhesive enabling removal of unused blister elements.
- Unused blister elements may include manufacturer's markings to provide a logistics trail to ensure that each blister element can be identified.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Packages (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
L'invention concerne un paquet distributeur (1) comprenant une première lamelle souple (2) et une seconde lamelle souple (3) ; la première lamelle souple (2) comprend un premier réseau d'ouvertures (4), et la seconde lamelle souple (3) comprend un second réseau d'ouvertures et une couche adhésive pouvant être exposée par retrait d'une feuille protectrice amovible (9) ; la première lamelle souple (2) et la seconde lamelle souple (3) étant conçues pour être appariées via le retrait de la feuille protectrice (9) et pour exposer la couche adhésive de telle sorte que le premier réseau et le second réseau d'ouvertures correspondent par alignement.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1007871.5 | 2010-05-11 | ||
GB201007871A GB2480281A (en) | 2010-05-11 | 2010-05-11 | Holder for a blister pack forming a monitored dosage system |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2011141688A1 true WO2011141688A1 (fr) | 2011-11-17 |
Family
ID=42315157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2011/000680 WO2011141688A1 (fr) | 2010-05-11 | 2011-05-05 | Paquet pour système de dosage surveillé |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB2480281A (fr) |
WO (1) | WO2011141688A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITPN20120042A1 (it) * | 2012-07-24 | 2014-01-25 | Sinteco S P A | Dispositivo perfezionato per la singolarizzazione di farmaci ed articoli medicali e relativo metodo di ottenimento |
EP3194293A1 (fr) * | 2014-09-16 | 2017-07-26 | Swisslog Italia S.p.A. | Support pour un médicament, en particulier dans une dose unitaire |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4362000A (en) * | 1978-05-30 | 1982-12-07 | Sterling Drug Inc. | Process and platform apparatus for producing packaging element |
EP0189276A2 (fr) | 1985-01-21 | 1986-07-30 | Manrex Limited | Emballage pour la distribution de médicaments |
GB2343440A (en) * | 1998-11-04 | 2000-05-10 | Venalink Ltd | Medicine pack |
WO2004101386A1 (fr) * | 2003-05-12 | 2004-11-25 | Meadwestvaco Corporation | Emballage-coque sur pour les enfants |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA866616A (en) * | 1971-03-23 | P. Dubbels Richard | Pill dispensing means | |
GB2266880A (en) * | 1992-05-16 | 1993-11-17 | Neal Charles Bryant | Blister package |
US5927500A (en) * | 1998-06-09 | 1999-07-27 | Milliken & Company | Pharmaceutical containment package |
GB0106361D0 (en) * | 2001-03-15 | 2001-05-02 | Fenn David J | Monitored dosage apparatus |
GB2385317B (en) * | 2002-02-14 | 2004-03-31 | Bringhigh Ltd | Package for small articles |
US7905355B2 (en) * | 2003-03-20 | 2011-03-15 | Key-Pak Technologies, Llc | Theft-resistant and senior-friendly packaging of consumer products |
CA2700930C (fr) * | 2007-09-26 | 2013-07-23 | Pioneer Hi-Bred International, Inc. | Appareil et procede de conditionnement d'articles pour leur stockage et leur identification |
-
2010
- 2010-05-11 GB GB201007871A patent/GB2480281A/en not_active Withdrawn
-
2011
- 2011-05-05 WO PCT/GB2011/000680 patent/WO2011141688A1/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4362000A (en) * | 1978-05-30 | 1982-12-07 | Sterling Drug Inc. | Process and platform apparatus for producing packaging element |
EP0189276A2 (fr) | 1985-01-21 | 1986-07-30 | Manrex Limited | Emballage pour la distribution de médicaments |
GB2343440A (en) * | 1998-11-04 | 2000-05-10 | Venalink Ltd | Medicine pack |
WO2004101386A1 (fr) * | 2003-05-12 | 2004-11-25 | Meadwestvaco Corporation | Emballage-coque sur pour les enfants |
Also Published As
Publication number | Publication date |
---|---|
GB2480281A (en) | 2011-11-16 |
GB201007871D0 (en) | 2010-06-23 |
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