WO2011139032A3 - 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물 - Google Patents

표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물 Download PDF

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WO2011139032A3
WO2011139032A3 PCT/KR2011/002805 KR2011002805W WO2011139032A3 WO 2011139032 A3 WO2011139032 A3 WO 2011139032A3 KR 2011002805 W KR2011002805 W KR 2011002805W WO 2011139032 A3 WO2011139032 A3 WO 2011139032A3
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amplifying
primers
target gene
primer
gene
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WO2011139032A2 (ko
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유왕돈
황선영
신수경
신지영
이주형
박선민
홍선표
김석준
김수옥
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(주)진매트릭스
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Priority to CN201180033690.5A priority Critical patent/CN102971437B/zh
Priority to US13/696,694 priority patent/US20130109016A1/en
Priority to JP2013508977A priority patent/JP2013529898A/ja
Priority to EP11777513.0A priority patent/EP2568052B1/en
Publication of WO2011139032A2 publication Critical patent/WO2011139032A2/ko
Publication of WO2011139032A3 publication Critical patent/WO2011139032A3/ko

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Abstract

본 발명의 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물은, 상기 표적 유전자의 분석 대상이 되는 유전자 변이 염기서열인 유전자형 분석 가능 서열이 포함된 적어도 하나의 주형에 각각 특이적인 적어도 하나의 프라이머를 포함하는 제1프라이머 군과, 상기 제1프라이머 군의 프라이머들 중 공통 염기서열이 가장 많은 프라이머 하나를 선정하고 이를 기준으로 하여 설계된 적어도 하나의 프라이머로서, 상기 주형에 특이적으로 결합하거나 3' 말단 근처에서 1∼2개의 염기서열 또는 연속적으로 3개까지의 염기서열이 상기 주형과 미스매칭되면서 상보적으로 결합하는 적어도 하나의 프라이머를 포함하는 제2프라이머 군을 포함한다.
PCT/KR2011/002805 2010-05-07 2011-04-20 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물 WO2011139032A2 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN201180033690.5A CN102971437B (zh) 2010-05-07 2011-04-20 扩增靶基因内存在多种变异的基因区域的引物组合物
US13/696,694 US20130109016A1 (en) 2010-05-07 2011-04-20 Primer composition for amplifying a gene region having various variations in a target gene
JP2013508977A JP2013529898A (ja) 2010-05-07 2011-04-20 標的遺伝子の多様な変異が存在する遺伝子領域を増幅するためのプライマー組成物
EP11777513.0A EP2568052B1 (en) 2010-05-07 2011-04-20 Method for producing an amplicon comprising a gene region having various variations and being useful in mass spectrometry

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020100043166A KR101287431B1 (ko) 2010-05-07 2010-05-07 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물, 이를 이용한 표적 유전자 증폭 방법 및 이를 포함하는 ｐｃｒ 증폭 키트 그리고 이를 이용한 표적 유전자의 유전자형 분석방법
KR10-2010-0043166 2010-05-07

Publications (2)

Publication Number Publication Date
WO2011139032A2 WO2011139032A2 (ko) 2011-11-10
WO2011139032A3 true WO2011139032A3 (ko) 2012-04-05

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Application Number Title Priority Date Filing Date
PCT/KR2011/002805 WO2011139032A2 (ko) 2010-05-07 2011-04-20 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물

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Country Link
US (1) US20130109016A1 (ko)
EP (1) EP2568052B1 (ko)
JP (1) JP2013529898A (ko)
KR (1) KR101287431B1 (ko)
CN (1) CN102971437B (ko)
WO (1) WO2011139032A2 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102025796B1 (ko) * 2012-07-31 2019-09-26 삼성전자 주식회사 디스플레이장치
TWI571763B (zh) * 2014-12-01 2017-02-21 財團法人資訊工業策進會 次世代定序分析系統及其次世代定序分析方法
CN111378645B (zh) * 2018-12-27 2020-12-01 江苏金斯瑞生物科技有限公司 一种基因合成的方法
CN112634990B (zh) * 2020-12-21 2021-10-12 广州市金域转化医学研究院有限公司 一种pcr引物设计模板筛选的方法及应用

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Also Published As

Publication number Publication date
KR101287431B1 (ko) 2013-07-19
WO2011139032A2 (ko) 2011-11-10
JP2013529898A (ja) 2013-07-25
CN102971437B (zh) 2015-04-15
EP2568052A4 (en) 2013-11-20
CN102971437A (zh) 2013-03-13
KR20110123604A (ko) 2011-11-15
US20130109016A1 (en) 2013-05-02
EP2568052A2 (en) 2013-03-13
EP2568052B1 (en) 2016-09-07

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