WO2011131474A2

WO2011131474A2 - Skin-gentle deodorants and antiperspirants

Info

Publication number: WO2011131474A2
Application number: PCT/EP2011/055195
Authority: WO
Inventors: Astrid Kleen; Susanne Hagenow
Original assignee: Henkel Ag & Co. Kgaa
Priority date: 2010-04-20
Filing date: 2011-04-04
Publication date: 2011-10-27
Also published as: WO2011131474A3; EP2680810A2; DE102010027947A1

Abstract

Cosmetic or dermatological skincare and skin-calmative deodorant or antiperspirant compositions, comprising at least one active deodorant or antiperspirant ingredient and at least one substituted cyclohexanol, can be boosted in their performance when they comprise at least one deodorant adjuvant from the groups of the silver salts and/or silver complexes and/or minerals of volcanic origin and/or zeolites and/or alum and/or active hair-growth inhibitor ingredients. Even over long storage times, these materials develop a skin-calmative and caring action, without any detraction from the care effect mediated by active deodorant and antiperspirant ingredients.

Description

Skin-friendly deodorants and antiperspirants

The present invention relates to cosmetic and dermatological antiperspirant and deodorant compositions which have a skin-friendly and caring effect.

Commercially available antiperspirant compositions, hereinafter also referred to as antiperspirants, contain as antiperspirant active ingredient at least one water-soluble astringent inorganic and organic salts of aluminum, zinc or selected aluminum-zirconium mixed salts. Commercially available deodorant compositions, also referred to below as deodorants, frequently contain at least one antibacterial active substance as the deodorant active ingredient.

The antiperspirant active ingredients have no direct influence on the activity of the sweat glands, but minimize the narrowing of the discharge channels sweat secretion. The AI salts cause thereby on the treated skin surfaces a sweat inhibition by superficial blockage of the sweat gland ducts as a result of Al-Mucopolysaccharid precipitation. Antiperspirant and deodorant compositions are usually applied and applied in the forearm region or in the region of the armpits. The skin in this area is usually more sensitive than the rest of the body's skin, often at least as sensitive as the skin on the face. There is therefore a constant need for particularly skin-compatible formulations which are suitable as carriers for cosmetic and dermatological antiperspirant and deodorant compositions. Furthermore, there is a need for particularly skin-friendly formulations which, as carriers for cosmetic and dermatological antiperspirant and deodorant compositions, may be able to make the antiperspirant and deodorant active ingredients that sometimes irritate the skin and make them more irritable to the skin or to reduce their irritative effect , In addition to the actual deodorant or antiperspirant active ingredients, deodorants and antiperspirants often contain other ingredients that enhance the effect or have additional effects. Certain salts and minerals, antibacterial agents or hair growth inhibitors are examples of such additional agents often employed.

To make the products more skin-friendly, special care agents are often used - but these are not always compatible with the deodorant and antiperspirant drugs and can be disabled by these. This deactivation of care substances is reinforced by the abovementioned additives, but their use is desirable for various reasons. There is therefore a need for substances which have a skin-care or soothing effect, but are also compatible with deodorant and antiperspirant active ingredients in combination with other adjuvants or active substances. The object of the present invention was to provide agents that develop a long-term storage times a soothing and nourishing effect, without resulting in a deterioration of the care effect of deodorant and antiperspirant active ingredients. In particular, the care substances should also be able to be used together with other active enhancers and hair growth inhibiting substances, without falling in their performance and without having to sacrifice the level of care-free products.

It has now been found that skin care and soothing cosmetic or dermatological deodorant or antiperspirant compositions with at least one deodorant or antiperspirant active ingredient and at least one substituted cyclohexanol can be improved in performance if they contain at least one deo-adjuvant from the groups of silver salts and / or silver complexes and / or minerals of volcanic origin and / or zeolites and / or alum and / or hair growth inhibiting agents.

Compositions containing frans-4-ferf-butyl-cyclohexanol are known, for example, from WO2009 / 087242 A2. Examples 32-36 also disclose deodorant compositions, without, however, going into potentizing minerals, salts or hair growth inhibitors. The present application therefore relates to cosmetic or dermatological deodorant or antiperspirant compositions containing in a cosmetically or dermatologically acceptable carrier

a) at least one deodorant or antiperspirant active ingredient,

b) frans-4-ferf-butyl-cyclohexanol,

c) at least one deodorant adjuvant from the groups of

i. Silver salts and / or

ii. Silver complexes and / or

iii. Minerals of volcanic origin and / or

iv. Zeolites and / or

v. Alum and / or

vi. Hair growth inhibiting agents.

According to the invention, the term "skin" generally refers to the skin itself, the mucous membrane and the skin appendages, insofar as they comprise living cells, in particular hair follicles, hair roots, hair bulbs, the anterior epithelium of the nail bed (lectorulus) as well as sebaceous glands and sweat glands. For the purposes of the invention, the generally used term "skin" is to be understood as meaning the "human skin".

The percentages by weight and ppm information always refer to the total weight of the composition according to the invention, without taking into account any propellant gas present. According to the invention preferred antiperspirant active substances are selected from aluminum chlorohydrates, especially aluminum chlorohydrates having the general formula [Al ₂ (OH) ₅ CI 2-3 ^■ H ₂ 0] _n, which may be present in non-activated or activated in (depolymerized) Form , further aluminum sesquichlorohydrate, aluminum chlorohydrex propylene glycol (PG) or aluminum chlorohydrex-polyethylene glycol (PEG), aluminum sesquichlorohydrex PG or PEG, aluminum PG-dichlorhydrex or aluminum PEG-dichlorhydrex, aluminum hydroxide, further selected from the aluminum zirconium chlorohydrates, such as aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate, aluminum zirconium octachlorohydrate, the aluminum Zirconium chlorohydrate-glycine complexes such as aluminum zirconium trichlorohydrex glycine, aluminum zirconium tetrachlorohydrex glycine, aluminum zirconium pentachlorohydrex glycine, aluminum zirconium octachlorohydrex glycine, sodium aluminum lactate + aluminum sulfate, sodium aluminum chlorhydroxactate, aluminum bromohydrate, aluminum chloride, the complexes of zinc and sodium salts, the complexes of lanthanum and cerium, the aluminum salts of lipoamino acids , Aluminum sulfate, aluminum lactate, aluminum chlorohydrate allantoinate, sodium aluminum chlorhydroxylactate, zinc chloride, zinc sulfate and zirconium chlorohydrate. According to the invention, water solubility is understood as meaning a solubility of at least 5% by weight at 20 ° C., that is to say amounts of at least 5 g of the antiperspirant active are soluble in 95 g of water at 20 ° C. The antiperspirant active ingredients can be used as aqueous solutions.

Particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that the at least one antiperspirant active ingredient is present in a total amount of 3 to 25 wt.%, Preferably 5 to 22 wt.% And in particular 10 to 20 wt. is contained, based on the total weight of the active substance according to USP in the overall composition. In a particularly preferred embodiment, the composition comprises an astringent aluminum salt, especially aluminum chlorohydrate, for example, in powder form as Micro Dry ^® Ultrafine from Reheis, in the form of an aqueous solution as Locron ^® L from Clariant, as Chlorhydrol ^® as well as in activated form as Reach ^® 501 Reheis is distributed. Under the name ^Reach® 301 an aluminum sesquichlorohydrate from Reheis is offered, which is likewise particularly preferred. The use of aluminum zirconium tetrachlorohydrex glycine complexes, which are, for example, by Reheis under the name Rezal ^® 36G commercially, may be particularly preferred according to the invention. In a further particularly preferred embodiment, the compositions according to the invention can contain both at least one deodorant and at least one antiperspirant active ingredient.

Deodorant actives

Deodorant active ingredients which are preferred according to the invention are silicates, zinc ricinoleate, cyclodextrins, organic germ-inhibiting agents, prebiotic active components and also enzyme inhibitors or, in particular, combinations of the active substances mentioned.

Among the silicates which are particularly preferred according to the invention are, in particular, phyllosilicates and, among these, in particular montmorillonite, kaolinite, mit, beidellite, nontronite, saponite, hectorite, benitite, smectite and talcum. They are preferably in an amount of 0.1 to 10 wt .-%, especially preferably 0.5 to 7 wt .-% and exceptionally 1 to 5 wt .-%, each based on the total composition used. Zinkricinoleat is also preferably in an amount of 0.5 to 7 wt .-% and most preferably 1-5 wt .-%, each based on the total composition included. Also, cyclodextrins are preferably in a total amount of 0.5 to 7 wt .-% and most preferably 1-5 wt .-%, each based on the total composition included.

According to the invention, organic germ-inhibiting or antimicrobial active ingredients are understood as meaning those organic active substances which reduce the number of skin germs participating in the formation of the odor or inhibit their growth. These organisms include, among others, various species from the group of staphylococci, the group of Corynebacteria, anaerococci and micrococci.

As organic germ-inhibiting or antimicrobial agents according to the invention are particularly preferred organohalogen compounds and quaternary ammonium compounds, a number of plant extracts and organic zinc compounds. These include triclosan, chlorhexidine and chlorhexidine gluconate, 3,4,4'-trichlorocarbanilide, bromochlorophene, dichlorophen, chlorothymol, chloroxylenol, hexachlorophene, dichloro-m-xylenol, dequalinium chloride, domibromium bromide, ammonium phenolsulfonate, benzalkonium halides, benzalkonium cetyl phosphate, benzalkonium saccharinates, benzethonium chloride, Cetylpyridinium chloride, laurylpyridinium chloride, laurylisoquinolinium bromide, methylbenzethonium chloride. Furthermore, phenol, phenoxyethanol, disodium dihydroxyethylsulfosuccinyl undecylenate, zinc lactate, sodium phenolsulfonate and zinc phenolsulfonate, ketoglutaric acid, terpene alcohols such. As farnesol, chlorophyllin copper complexes, alpha-monoalkyl glycerol ether with a branched or linear saturated or unsaturated, optionally hydroxylated C ₆ - C ₂₂ alkyl, particularly preferably alpha- (2-ethylhexyl) glycerol ether, commercially available as Sensiva ^® SC 50 (ex Schülke & Mayr), carboxylic acid esters of mono-, di- and triglycerin (eg glycerol monolaurate, diglycerol monocaprate) and plant extracts (eg green tea and components of lime blossom oil) are preferred.

Further preferred deodorant active substances are selected from so-called prebiotic active components, which according to the invention are to be understood as meaning those components which inhibit only or at least predominantly the odor-causing germs of the skin microflora, but not the desired ones, that is to say the non-odor-causing germs belonging to a healthy skin microflora. Specifically included here are conifer extracts, especially from the group of Pinaceae, and plant extracts from the group of Sapindaceae, Araliaceae, Lamiaceae and Saxifragaceae, in particular extracts of Picea spp., Paullinia sp., Panax sp., Lamium album or Ribes nigrum and mixtures thereof substances.

The enzyme inhibitors include substances which inhibit the enzymes responsible for the sweat decomposition, in particular arylsulfatase, beta-glucuronidase, aminoacylase, esterases, lipases and / or lipoxigenase, e.g. B. trialkylcitric acid, in particular triethyl citrate, or zinc glycinate. Preferred deodorant or antiperspirant compositions according to the invention are characterized in that the at least one deodorant active ingredient is selected from arylsulfatase inhibitors, beta-glucuronidase inhibitors, aminoacylase inhibitors, esterase inhibitors, lipase inhibitors and lipoxigenase inhibitors, alpha Monoalkylglycerinethern with a branched or linear saturated or unsaturated, optionally hydroxylated C ₆ - C ₂ 2-alkyl radical, in particular alpha- (2-ethylhexyl) glycerol ether, phenoxyethanol, prebiotic components, trialkylcitric acid esters, in particular triethyl citrate, active compounds which have the number of on the Odor-forming skin bacteria from the group of staphylococci, Corynebacteria, anaerococci and micrococci reduce or inhibit their growth, organic zinc compounds, especially zinc phenolsulfonate and Zinkricinoleat, Organohalogenverbindungen, in particular triclosan, chlorhexidine, Chlorhexidingluc onat and benzalkonium halides, quaternary ammonium compounds, in particular cetylpyridinium chloride, and mixtures of the abovementioned substances.

Further preferred deodorant or antiperspirant compositions according to the invention are characterized in that the at least one deodorant active ingredient is present in a total amount of 0.1-10% by weight, preferably 0.2-7% by weight, particularly preferably 0.3 - 5 wt .-% and most preferably 0.4 - 1, 0 wt .-%, each based on the total weight of the active substance of the deodorant active ingredient or the deodorant active ingredients in the overall composition is included.

As a further essential ingredient, the compositions according to the invention contain frans-4-hept-butyl-cyclohexanol. In the context of the present invention, the term frans-4-ferf-butyl-cyclohexanol encompasses both the (+) - frans-4-ferf-butyl-cyclohexanol of the formula (I) and the (-) - frans-4-ferf Butyl-cyclohexanol of the formula (II) and mixtures thereof, in particular their racemic mixture.

Particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that they contain, based on their weight, from 0.05 to 10% by weight, preferably from 0.1 to 7.5% by weight, more preferably from 0.25 to 5 wt .-%, particularly preferably 0.5 to 2.5 and in particular 0.6 to 1, 25 wt .-% frans-4-ferf-butyl-cyclohexanol. The agents according to the invention are enhanced in performance by the addition of deodorant adjuvants without losing their advantageous properties in terms of skin care and skin care. They contain at least one deodorant adjuvant from the groups of silver salts and / or silver complexes and / or minerals of volcanic origin and / or zeolites and / or alum and / or hair growth-inhibiting active ingredients. In this way it is possible to provide means with superior performance level with optimal care properties.

As silver salts and / or silver complexes, in particular silver nitrate, silver acetate, silver sulfate and silver citrate are suitable; silver citrate-citric acid complexes of the formula are also preferred

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc.

Alternatively or additionally, silver lactate and / or silver lactate-lactic acid complexes of the form are also suitable

COO

x H y Ag

HO-H

CH ₃

x + y = 1

or the form

1

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver lactate has a molecular weight of 196.94 g / mol. Silver has a molecular weight of 107.87 g / mol. Preferred compositions according to the invention are characterized in that silver lactate is present in a total amount of 1.8 to 182 ppm, preferably 3.6 to 91.3 ppm, more preferably 9.6 to 35.5 ppm, most preferably 12.8 to 18.3 ppm, in each case based on the weight of the composition according to the invention. Alternatively or in addition to this, silver acetate and / or silver acetate-acetic acid complexes of the form are also suitable

x + y = 1

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver acetate has a molecular weight of 166.92 g / mol. Preferred compositions according to the invention are characterized in that silver acetate in a total amount of 1.5-154.7 ppm, preferably 3.1-77.4 ppm, more preferably 7.7-30.9 ppm, most preferably 10.8-15 , 5 ppm, in each case based on the weight of the composition according to the invention.

Alternatively or in addition to this, silver sulfate and / or silver sulfate-sulfuric acid complexes of the form are also suitable

O ^"

x H ⁺ y Ag ⁺

O = S = O

O ^"

x + y = 2

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver sulfate has a molecular weight of 31 1, 8 g / mol. Preferred compositions according to the invention are characterized in that silver sulfate in a total amount of 1.4 to 145 ppm, preferably 2.9 to 72.3 ppm, more preferably 7.2 to 28.9 ppm, most preferably 10.1 to 14.5 ppm, in each case based on the weight of the composition according to the invention.

Alternatively or in addition to this, silver malate and / or silver malate-hydroxysuccinic acid complexes of the form are also suitable

or the form

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver malate has a molecular weight of 347.83 g / mol. Preferred compositions according to the invention are characterized in that silver malate is present in a total amount of 1.6-161.2 ppm, preferably 3.2-80.6 ppm, more preferably 8.1-32.2 ppm, most preferably 11, 3-16.1 ppm, each based on the weight of the composition according to the invention is included.

Alternatively or additionally, silver succinate and / or silver succinate succinic acid complexes of the form are also suitable

+

x + y = 2

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver succinate has a molecular weight of 331, 83 g / mol. Preferred compositions according to the invention are characterized in that silver succinate is present in a total amount of 1.5-15.3.8 ppm, preferably 3. 1-76.9 ppm, more preferably 7.7-30.8 ppm, most preferably 10.8-15 , 4 ppm, in each case based on the weight of the composition according to the invention.

Alternatively or additionally, silver tartrate and / or silver tartrate-tartaric acid complexes of the form are also suitable

or the form

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver tartrate has a molecular weight of 363.83 g / mol. Preferred compositions according to the invention are characterized in that silver tartrate in a total amount of 1.7-168.6 ppm, preferably 3.4-84.3 ppm, more preferably 8.4-33.7 ppm, most preferably 1 1, 8 16.9 ppm, in each case based on the weight of the composition according to the invention, is contained.

Alternatively or in addition to this, silver mandelate and / or silver mandelate-mandelic acid complexes are also of the form

or the form

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver mandelate has a molecular weight of 259.02 g / mol. Preferred compositions according to the invention are characterized in that silver mandelate in a total amount of 2.4-240, 1 ppm, preferably 4.8-120 ppm, particularly preferably 12-48 ppm, most preferably 16.8-24 ppm, in each case based on the Weight of the composition of the invention is included.

Alternatively or additionally, silver salicylate and / or silver salicylate-salicylic acid complexes of the form are also suitable

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver salicylate has a molecular weight of 244.99 g / mol. Preferred compositions according to the invention are characterized in that silver salicylate in a total amount of 2.3-222.1 ppm, preferably 4.5-1 13.6 ppm, more preferably 11-45.4 ppm, most preferably 15.9 - 22.7 ppm, in each case based on the weight of the composition according to the invention is contained.

Alternatively or additionally, silver gluconate and / or silver gluconate-gluconic acid complexes of the form are also suitable

with a water content of 0 up to 90 wt .-%, based on the total mass of the complex, preferably in combination with one or more compounds selected from the group of phyllosilicates and / or talc, preferably. Silver gluconate has a molecular weight of 303.03 g / mol. Preferred compositions according to the invention are characterized in that silver gluconate in a total amount of 2.8-280.9 ppm, preferably 5.6-140.4 ppm, more preferably 14-56.2 ppm, most preferably 19.7-28.1 ppm, in each case based on the weight of the composition according to the invention.

Regardless of which silver salt (s) or silver complex (s) are used in the compositions of the present invention, preference is given to deodorant or antiperspirant compositions according to the invention which, by weight, contain silver ions in a total amount of 1-100 ppm , preferably 2 - 50 ppm, more preferably 5 - 20 ppm, most preferably 7 - 10 ppm, each based on the weight of the composition according to the invention.

In a further preferred embodiment, the compositions according to the invention contain one or more deodorant adjuvants from the groups of minerals of volcanic origin and / or zeolites and / or alum and / or the hair growth-inhibiting active ingredients.

Minerals of volcanic origin, so-called volcanics, are magmatic rocks that have risen as molten magma, flowed out by volcanoes and solidified (eruptive, effusive, effusion, extrusive rocks). As a result of the rapid cooling, the volcanics are usually finely crystalline; they may contain vitreous components in the matrix or may even be completely glassy (eg obsidian, pumice stone). Feldspars are essential components in almost all volcanics. For the description and determination a distinction is made as between the Plutonites (magmatic rocks) between Kalkalkali volcanics (for example, rhyolite, dacite, andesite, Tholeiitbasalt) and alkali volcanics (eg trachyte, phonolite, alkali basalts, lamproite). In chemical analyzes of calcium alkali volcanics, K ₂ O + Na ₂ O <Al ₂ O ₃ (mol%).

As mineral of volcanic origin, in the context of the present invention, in particular perlite (perlite) have proven to be suitable. Perlites are light gray, also black volcanic rock glass of rhyolite composition with 70-76% Si0 ₂ , 1 1-18% Al ₂ 0 ₃ , 4-6% K ₂ 0 u. 2-7% water. Regardless of which volcanic rock (s) are used in the compositions of the present invention, preference is given to deodorant or antiperspirant compositions according to the invention which, by weight, are from 0.05 to 15% by weight, preferably 0.1 to 12.5% by weight, more preferably 0.25 to 10% by weight, particularly preferably 0.5 to 7.5 and in particular 0.6 to 5% by weight of minerals of volcanic origin, in particular perlite , contain.

Zeolites are crystalline aluminosilicates of the formula M ₂ / _z O ^■ Al ₂ 0 ₃ ^■ ^■ xSi0 ₂ yH ₂ 0, where M = mono- or polyvalent metal ion (usually an alkali or alkaline earth cation), and H or NH _4, z = valence of the cation, x = 1, 8 to about 12 and y = 0 to about 8.

According to their crystal lattices, the natural zeolites can be classified into fiber zeolites (natrolite, laumontite, mordenite, thomsonite), zeolite zeolites (heulandite, stilbite, phillipsite, harmotom, yugawa ralith) and the so-called cube zeolites (faujasite, gmelinite, chabazite, offretite, levyn) that have a cubic or pseudocubic lattice.

The synthetic zeolites are divided into pore sizes in narrow, medium and wide pore types. Within this group there are more than 150 different framework structures, which often differ in the Si / Al ratio (modulus). In the general literature and patent literature, synthetic zeolites were first given trivial names: zeolite A [modulus 2, pore size 0.4 nm (Na)], zeolite X [modulus 2-3, pore size 0.7 nm (Na)], zeolite Y [Module 3-6, pore size 0.7 nm (Na)], zeolite L [modulus 6-10, pore size 0.7 nm (K)], synthetic mordenite (modulus about 10, pore size 0.7 nm). Later, the International Zeolite Association (IZA) introduced a three-letter mnemonic code to clearly distinguish each type of scaffold. For example, MOR stands for mordenite or BEA for zeolite beta.

Regardless of which zeolite (s) are used in the compositions according to the invention, preference is given to deodorant or antiperspirant compositions according to the invention which, based on their weight, are from 0.05 to 15% by weight, preferably from 0 to 1 10 wt .-%, more preferably 0.25 to 5 wt .-%, particularly preferably 0.5 to 2 and in particular 0.6 to 1 wt .-% zeolites.

The compositions of the invention may contain at least one double salt of the alum type having the general formula M ^l M ^l "(S0 ₄₎ ₂ x H ₂ 0 ^■ contain, where M ¹ is a monovalent cation selected from potassium, sodium, rubidium, Cesium and ammonium ions, M ¹ "is a trivalent cation selected from aluminum, gallium, indium, scandium, titanium and vanadium ions, and x is a rational number in the range of 0 to 12, including 0, represent.

Particularly preferred are the double salts with M ^m = aluminum ion, in particular KAI (S0 ₄ ) ₂ , KAI (S0 ₄ ) ₂ ^■ 1 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 2 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 3 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 4 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 5 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 6 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 7 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 8 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 9 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 10 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 1 1 H ₂ 0 and KAI (S0 ₄ ) ₂ ^■ 12 H ₂ O, NH ₄ Al (S0 ₄ ) ₂ , NH ₄ Al (S0 ₄ ) ₂ - 1 H ₂ 0,

NH ₄ Al (SO ₄ ) ₂ -2H ₂ O, NH ₄ Al (SO ₄ ) ₂ 3 H ₂ O, NH ₄ Al (SO ₄ ) ₂ -4 H ₂ O, NH ₄ Al (SO ₄ ) ₂ 5 H ₂ 0,

NH ₄ AI (S0 ₄₎ ₄ ₂ -6 H ₂ 0, NH ₄ AI (S0 ₄₎ ₂ -7 H ₂ 0, NH ₄ AI (S0 ₄₎ ₂ ^■ 8 H ₂ 0, NH AI (S0 ₄₎ ₂ ^{■ 9H} ₂ 0,

NH ₄ AI (S0 ₄₎ ₂ ^■ 10 H ₂ 0, NH ₄ AI (S0 ₄₎ ₂ ^■ 1 1 H ₂ 0 and NH ₄ AI (S0 ₄₎ ₂ ^■ 12 H ₂ 0, RBAI (S0 ₄₎ _2, RBAI (S0 ₄₎ ₂ ^■ 1 H ₂ 0, RBAI (S0 ₄₎ ₂ ^■ 2H ₂ 0, RBAI (S0 ₄₎ ₂ ^■ 3 H ₂ 0, RBAI (S0 ₄₎ ₂ ^■ 4 H ₂ 0,

RBAI (S0 ₄₎ ₂ ^■ 5 H ₂ 0, RBAI (S0 ₄₎ ₂ ^■ 6H ₂ 0, RBAI (S0 ₄₎ ₂ ^■ 7H ₂ 0, RBAI (S0 ₄₎ ₂ ^■ 8 H ₂ 0,

RbAI (S0 ₄ ) ₂ ^■ 9 H ₂ 0, RbAI (S0 ₄ ) ₂ ^■ 10 H ₂ 0, RbAI (S0 ₄ ) ₂ ^■ 1 1 H ₂ 0 and RbAI (S0 ₄ ) ₂ ^■ 12 H ₂ 0, NaAl (S0 ₄ ) ₂ , NaAl (S0 ₄ ) ₂ ^■ 1 H ₂ 0, NaAl (S0 ₄ ) ₂ ^■ 2 H ₂ 0, NaAl (SO ₄ ) ₂ ^■ 3 H ₂ 0, NaAl (SO ₄ ) ₂ ^■ 4 H ₂ 0, NaAl (S0 ₄₎ ₂ ^■ 5 H ₂ 0, NaAl (S0 ₄₎ ₂ ^■ 6H ₂ 0, NaAl (S0 ₄₎ ₂ ^■ 7H ₂ 0, NaAl (S0 ₄₎ ₂ ^■ 8 H ₂ 0

NaAl (S0 ₄₎ ₂ ^■ 9 H ₂ 0, NaAl (S0 ₄₎ ₂ ^■ 10 H ₂ 0, NaAl (S0 ₄₎ ₂ ^■ 1 1 H ₂ 0 and NaAl (S0 ₄₎ ₂ ^■ 12 H ₂ 0, KSc (S0 ₄ ) ₂ , KSc (S0 ₄ ) ₂ ^■ 1 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 2 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 3 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 4 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 5 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 6 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 7 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 8 H ₂ 0

KSc (S0 ₄ ) ₂ ^■ 9 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 10 H ₂ 0, KSc (S0 ₄ ) ₂ ^■ 11 H ₂ 0 and KSc (S0 ₄ ) ₂ ^■ 12 H ₂ 0,

NH ₄ Sc (SO ₄ ) ₂ , NH ₄ Sc (SO ₄ ) ₂ ^■ 1 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 2 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 3 H ₂ O .

NH ₄ Sc (SO ₄ ) ₂ ^■ 4 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 5 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 6 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 7 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 8 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 9 H ₂ O, NH ₄ Sc (SO ₄ ) ₂ ^■ 10 H ₂ O, NH ₄ Sc (S0 ₄ ) ₂ ^■ 11 H ₂ O and NH ₄ Sc (S0 ₄ ) ₂ ^■ 12 H ₂ O, RbSc (S0 ₄ ) ₂ , RbSc (S0 ₄ ) ₂ ^■ 1 H ₂ 0, RbSc (S0 ₄ ) ₂ ^{■ 2H} ₂ 0,

RBSC (S0 ₄₎ ₂ ^■ 3 H ₂ 0, RBSC (S0 ₄₎ ₂ ^■ 4 H ₂ 0, RBSC (S0 ₄₎ ₂ ^■ 5 H ₂ 0, RBSC (S0 ₄₎ ₂ ^■ 6H ₂ 0,

RBSC (S0 ₄₎ ₂ ^■ 7H ₂ 0, RBSC (S0 ₄₎ ₂ ^■ 8 H ₂ 0, RBSC (S0 ₄₎ ₂ ^■ 9 H ₂ 0, RBSC (S0 ₄₎ ₂ ^■ 10 H ₂ 0,

RbSc (S0 ₄ ) ₂ ^■ 11 H ₂ O and RbSc (S0 ₄ ) ₂ ^■ 12 H ₂ O, NaSc (S0 ₄ ) ₂ , NaSc (S0 ₄ ) ₂ ^■ 1 H ₂ 0,

Nasc (S0 ₄₎ ₂ ^■ 2H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 3 H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 4 H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 5 H ₂ 0,

Nasc (S0 ₄₎ ₂ ^■ 6H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 7H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 8 H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 9 H ₂ 0,

Nasc (S0 ₄₎ ₂ ^■ 10 H ₂ 0, nasc (S0 ₄₎ ₂ ^■ 11 H ₂ 0 and nasc (S0 ₄₎ ₂ ^■ 12 H ₂ 0, KGa (S0 ₄₎ _2,

KGa (S0 ₄ ) ₂ ^■ 1 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 2 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 3 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 4 H ₂ 0,

KGa (S0 ₄ ) ₂ ^■ 5 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 6 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 7 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 8 H ₂ 0,

KGa (S0 ₄ ) ₂ ^■ 9 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 10 H ₂ 0, KGa (S0 ₄ ) ₂ ^■ 11 H ₂ 0 and KGa (S0 ₄ ) ₂ ^■ 12 H ₂ 0, NH ₄ Ga (S0 ₄₎ _2, NH ₄ Ga ₂ (S0 ₄₎ ₂ ^■ 1 H ₂ 0, NH ₄ Ga (S0 ₄₎ ^■ 2 H ₂ 0, NH ₄ Ga (S0 ₄₎ ₂ ^■ 3 H ₂ 0,

NH ₄ Ga (SO ₄ ) ₂ ^■ 4 H ₂ O, NH ₄ Ga (SO ₄ ) ₂ ^■ 5 H ₂ O, NH ₄ Ga (SO ₄ ) ₂ ^■ 6 H ₂ O, NH ₄ Ga (SO ₄ ) ₂ ^■ 7 H ₂ O, NH ₄ Ga (SO ₄ ) ₂ ^■ 8 H ₂ O, NH ₄ Ga (SO ₄ ) ₂ ^■ 9 H ₂ O, NH ₄ Ga (SO ₄ ) ₂ ^■ 10 H ₂ O, NH ₄ Ga (S0 ₄ ) ₂ ^■ 1 1 H ₂ 0 and NH ₄ Ga (S0 ₄ ) ₂ ^■ 12 H ₂ 0, RbGa (S0 ₄ ) ₂ , RbGa (S0 ₄ ) ₂ ^■ 1 H ₂ 0, RbGa (S0 ₄ ₂ ^2H ₂ 0,

RbGa (S0 ₄ ) ₂ ^■ 3 H ₂ 0, RbGa (S0 ₄ ) ₂ ^■ 4 H ₂ 0, RbGa (S0 ₄ ) ₂ ^■ 5 H ₂ 0, RbGa (S0 ₄ ) ₂ ^■ 6 H ₂ 0,

RbGa (S0 ₄ ) ₂ ^■ 7 H ₂ 0, RbGa (S0 ₄ ) ₂ ^■ 8 H ₂ 0, RbGa (S0 ₄ ) ₂ ^■ 9 H ₂ 0, RbGa (S0 ₄ ) ₂ ^■ 10 H ₂ 0, RbGa ( S0 ₄ ) ₂ ^■ 11 H ₂ 0 and RbGa (S0 ₄ ) ₂ ^■ 12 H ₂ 0, NaGa (S0 ₄ ) ₂ , NaGa (S0 ₄ ) ₂ ^■ 1 H ₂ 0,

NaGa (S0 ₄₎ ₂ ^■ 2H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 3 H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 4 H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 5 H ₂ 0,

NaGa (S0 ₄₎ ₂ ^■ 6H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 7H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 8 H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 9 H ₂ 0,

NaGa (S0 ₄₎ ₂ ^■ 10 H ₂ 0, NaGa (S0 ₄₎ ₂ ^■ 11 H ₂ 0 and NaGa (S0 ₄₎ ₂ ^■ 12 H ₂ 0, KTi (S0 ₄₎ _2,

KTi (S0 ₄ ) ₂ ^■ 1 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 2 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 3 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 4 H ₂ 0, KTi ( S0 ₄ ) ₂ ^■ 5 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 6 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 7 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 8 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 9 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 10 H ₂ 0, KTi (S0 ₄ ) ₂ ^■ 1 1 H ₂ 0 and KTi (S0 ₄ ) ₂ ^■ 12 H ₂ 0, NH ₄ Ti (S0 ₄ ) ₂ , NH ₄ Ti (SO ₄ ) ₂ ^■ 1 H ₂ O,

NH ₄ Ti (S0 ₄₎ ₂ -2 H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^■ 3 H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^■ 4 H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^{■ 5H} ₂ 0,

NH ₄ Ti (S0 ₄₎ ₂ ^■ 6H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^■ 7 H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^■ 8 H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^{■ 9H} ₂ 0,

NH ₄ Ti (S0 ₄₎ ₂ ^■ 10 H ₂ 0, NH ₄ Ti (S0 ₄₎ ₂ ^■ 1 1 H ₂ 0 and NH ₄ Ti (S0 ₄₎ ₂ ^■ 12 H ₂ 0, RBTI (S0 ₄₎ _2,

RbTi (S0 ₄ ) ₂ ^■ 1 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 2 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 3 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 4 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 5 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 6 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 7 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 8 H ₂ 0,

RbTi (S0 ₄ ) ₂ ^■ 9 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 10 H ₂ 0, RbTi (S0 ₄ ) ₂ ^■ 11 H ₂ 0 and RbTi (S0 ₄ ) ₂ ^■ 12 H ₂ 0, NaTi ( S0 ₄ ) ₂ , NaTi (S0 ₄ ) ₂ ^■ 1 H ₂ 0, NaTi (S0 ₄ ) ₂ ^■ 2 H ₂ 0, NaTi (S0 ₄ ) ₂ ^■ 3 H ₂ 0, NaTi (S0 ₄ ) ₂ ^■ 4 H ₂ 0, NaTi (S0 ₄₎ ₂ ^■ 5 H ₂ 0, NaTi (S0 ₄₎ ₂ ^■ 6H ₂ 0, NaTi (S0 ₄₎ ₂ ^■ 7H ₂ 0, NaTi (S0 ₄₎ ₂ ^■ 8 H ₂ 0 .

NaTi (S0 ₄₎ ₂ ^■ 9 H ₂ 0, NaTi (S0 ₄₎ ₂ ^■ 10 H ₂ 0, NaTi (S0 ₄₎ ₂ ^■ 11 H ₂ 0 and NaTi (S0 ₄₎ ₂ 12H ₂ ^■ 0th

Particularly preferred are KAI (S0 ₄ ) ₂ , KAI (S0 ₄ ) ₂ ^■ 1 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 2 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 3 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 4 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 5 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 6 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 7 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 8 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 9 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 10 H ₂ 0, KAI (S0 ₄ ) ₂ ^■ 11 H ₂ 0 and KAI (S0 ₄ ) ₂ ^■ 12 H ₂ 0.

Salts with a water content of less than 12 molecules per molecule of alum are produced by heating alum. From a temperature of about 60 ° C up to 25% of the water of crystallization already escape, preferred temperatures for further dewatering are 500 ° C or less, preferably 300 ° C or less, more preferably 250 ° C or less, most preferably 200 ° C or less, most preferably 90-150 ° C. Completely dewatered alum (also called fired alum) or partially dewatered alum may, at least in higher concentrations, disperse better than alums having a water content of less than 12 molecules per molecule and may therefore be preferred for the compositions of this invention.

After completion of the dewatering process to the desired level of water of crystallization, the alum is brought to the desired particle size by milling or other crushing and screening processes. For the compositions according to the invention, in particular for spray compositions, alum particles are preferred which have a number average particle size of 0.1-150 μιη, preferably 1-80 μιη, more preferably 5-60 μιη and exceptionally preferably 10-30 μιη.

Regardless of which alum (s) are used in the compositions according to the invention, preference is given to deodorant or antiperspirant compositions according to the invention which, based on their weight, are from 0.05 to 10% by weight, preferably from 0.1 to 5 wt .-%, more preferably 0.2 to 3 wt .-%, particularly preferably 0.5 to 2 and in particular 0.7 to 1 wt .-% alum (s) included.

Particularly preferred, because with the trans-4-tert-butyl-cyclohexanol particularly compatible hair growth inhibiting substances are derivatives of 3-hydroxy-4 (1 H) -pyridone and so-called advanced glycation endproducts (AGE).

Agents preferred according to the invention comprise at least one derivative of the 3-hydroxy-4 (1H) -pyridone of the general formula (I)

in which

the radical R 1 is a C ₁ -C ₆ -alkyl group, a C ₂ -C ₆ -alkenyl group, a C ₂ -C ₆ -hydroxyalkyl group, a C ₂ -C ₆ -polyhydroxyalkyl group, a C ₁ -C ₆ -alkoxy-C ₂ -C ₆ alkyl group, a C- | _-C6 - cyanoalkyl group, an amino-C ₂ -C ₆ alkyl group, a di (C- | -C ₆ alkyl) amino-C ₂ -C ₆ -alkylgrup - Pe, an aryl group, an aryl-Ci-C6-alkyl group, a heteroaryl group or a heteroaryl-C -C _ö alkyl group or one of the following structural units (2) to (10)

where n stands for a natural number of 2 to 6 in this context,

the two radicals R2 and R3 independently of one another represent a hydrogen atom, a

C 1 -C ₆ -alkyl group, a C ₂ -C ₆ -hydroxyalkyl group or a hydroxy group,

R 1 and R 2 or R 1 and R 3 together may form a five- or six-membered saturated ring system which may optionally contain further heteroatoms or may carry further substituents,

the radical R4 contained in the substructure (7) is a C ₁ -C ₄ -alkyl group, a C ₂ -C ₆ -alkenyl group or a C ₂ -C ₆ -hydroxyalkyl group.

The radical R ₁ in formula (I) can, in a preferred embodiment of the present invention, be a C 1-6 -alkyl group or a C ₂ . ₆ alkenyl group stand. Preferred deodorant or antiperspirant compositions according to the invention are characterized in that they contain at least one derivative of the 3-hydroxy-4 (1H) -pyridone of the general formula (I) in which the radical R 1 is a C ₁ -C ₆ -alkyl group , preferred for -CH ₃ , -CH ₂ CH ₃ , - (CH ₂ ) ₂ CH ₃ , -CH (CH ₃ ) ₂ , - (CH ₂ ) ₃ CH ₃ , CH ₂ CH (CH ₃ ) ₂ , -C (CH ₃ ) ₃ , - (CH ₂ ) ₄ CH ₃ , - (CH ₂ ) ₅ CH ₃ or for a C ₂ -C ₆ alkenyl group, preferably for -CH = CH ₂ , -CH ₂ -CH = CH ₂ , - (CH ₂ ) ₂ -CH = CH ₂ , - (CH ₂ ) ₃ -CH = CH ₂ , - (CH ₂ ) ₄ -CH = CH ₂ .

In a further preferred embodiment of the present invention, the radical R 1 can be a C ₂ -C ₆ -hydroxyalkyl group or a C ₂ -C ₆ -polyhydroxyalkyl group or a C 1 -C ₆ -alkoxy-C ₂ -C ₆ -alkyl group. Preferred deodorant or antiperspirant according to the invention Compositions of this embodiment contain at least one derivative of the 3-hydroxy-4 (1 H) -pyridone of the general formula (I) in which the radical R 1 is a C ₂ -C ₆ -hydroxyalkyl group, a C ₂ -C ₆ -polyhydroxyalkyl group or a C ₁ -C ₆ -alkoxy-C ₂ -C ₆ -alkyl group, preferred for -CH ₂ OH, - (CH ₂ ) ₃ OH, - (CH ₂ ) (CHOH) CH ₂ OH, - (CH ₂ ) ₂ (CHCOH) CH ₂ OH, - (CH ₂ ) ₂ (CHCH ₃ ) CH ₂ OH, - (CH ₂ ) ₂ -O-CH ₃ , - (CH ₂ ) ₂ -O-CH ₂ -CH ₃ , - ( CH2) ₃ -0-CH ₃ or - (CH ₂₎ ₃ -0-CH ₂ -CH _3.

In a further preferred embodiment of the present invention, the radical R 1 can be a C ₁ -C ₆ -cyanoalkyl group, an aminoC 1 -C ₆ -alkyl group or a di (C ₁ -C ₆ -alkyl) aminoC ₂ -C ₆ -alkyl group , Preferred deodorant or antiperspirant compositions of this embodiment according to the invention are characterized in that they comprise at least one derivative of the 3-hydroxy-4 (1H) -pyridone of the general formula (I) in which the radical R 1 is C 1-1 -C ₆ cyanoalkyl group, an amino C ₂ -C ₆ alkyl group or a di- (C 1 -C ₆ alkyl) aminoC ₂ -C ₆ alkyl group, preferably -CH ₂ CN, - (CH ₂ ) ₂ CN, - (CH ₂ ) ₃ CN, - (CH ₂ ) ₂ NH ₂ , - (CH ₂ ) ₃ NH ₂ , - (CH ₂ ) ₂ N (CH ₃ ) ₂ , - (CH ₂ ) ₃ N (CH ₃ ) ₂ , - (CH ₂ ) ₂ N (CH ₂ CH ₃ ) ₂ or - (CH ₂ ) ₃ N (CH ₂ CH ₃ ) ₂ .

Regardless of the choice of the radical R1 compounds of general formula (I) are preferred in the invention, in which the radical R2 is a C-C _ö alkyl group. Preferred deodorant or antiperspirant compositions according to the invention comprise at least one derivative of the 3-hydroxy-4 (1H) -pyridone of the general formula (I) in which the radical R 2 is a C ₁ -C 6 -alkyl group, preferably -CH ₃ , -CH ₂ CH ₃ , - (CH ₂ ) ₂ CH ₃ , -CH (CH ₃ ) ₂ , - (CH ₂ ) ₃ CH ₃ , -C (CH ₃ ) ₃ , -CH ₂ CH (CH ₃ ) ₂ , - (CH ₂ ) ₄ CH ₃ , - (CH ₂ ) ₅ CH ₃ and in particular represents a methyl group.

Regardless of the choice of R 1 and R 2 are according to the invention compounds of general formula (I) are preferred, in which the radical R3 is -H or Ci-C _ö alkyl group. Preferred deodorant or antiperspirant compositions according to the invention therefore contain at least one derivative of the 3-hydroxy-4 (1H) -pyridone of the general formula (I) in which the radical R3 is -H.

In particularly preferred agents according to the invention, simultaneously R ₂ = -CH ₃ and R ₃ = -H. Depending on the choice of the radical R1, particularly preferred compounds of the formula (I) are obtained. When the radical R ₁ in formula (I) according to a preferred embodiment of the present invention is a C 1-6 -alkyl group or a C ₂ . _6- alkenyl group, particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that they are used as derivatives of the 3-hydroxy-4 (1H) -pyridone of the general formula (I)

3-hydroxy-1,2-dimethylpyridine-4 (1H) -one

and or 1-ethyl-3-hydroxy-2-methylpyridine-4 (1H) -one

3-hydroxy-2-methyl-1-propylpyridine-4 (1H) -one

1-Allyl-3-hydroxy-2-methylpyridine-4 (1H) -one

contain.

When the radical R 1 in formula (I), according to another preferred embodiment of the present invention for a C ₂ -C ₆ hydroxyalkyl or a C ₂ -C ₆ -polyhydroxyalkyl group or a -C ₆ -alkoxy-C ₂ -C ₆ alkyl group , particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that they are used as derivatives of the 3-hydroxy-4 (1H) -pyridone of the general formula (I)

3-hydroxy-1- (2-hydroxyethyl) -2-methylpyridine-4 (1H) -one

3-hydroxy-1 - (3-hydroxypropyl) -2-methylpyran-i-4 (1H) -one

and or 1- (2-ethoxyethyl) -3-hydroxy-2-methylpyridine-4 (1H) -one

3-hydroxy-1- (3-methoxypropyl) -2-methylpyridine-4 (1H) -one

1- (3-ethoxypropyl) -3-hydroxy-2-methylpyridine-4 (1H) -one

contain.

If the radical R 1 in formula (I) according to a further preferred embodiment of the present invention is a C 1 -C ₆ -cyanoalkyl group, an aminoC ₂ -C ₆ -alkyl group or a di- (C ₁ -C ₆ -alkyl) amino-C ₂ -C ₆ -alkyl group, particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that they are used as derivatives of the 3-hydroxy-4 (1H) -pyridone of the general formula (I)

(3-hydroxy-2-methyl-4-oxopy-1-yl-1 (4H) -y1) acetonitrile I

3- (3-Hydroxy-2-methyl-4-oxopyridine-1 (4H) -yl) -propanenitrile

and or

and or

contain.

According to another preferred embodiment of the present invention, the remainder

R1 may be selected from the structural units (2) to (10). Particularly preferred radicals R 1 are the structural units (2), (3), (4) or (8). In very particularly preferred compounds according to the invention of this embodiment, R _{2 is} -CH ₃ and R _{3 is} simultaneously -H. Very particularly preferred deodorant or antiperspirant compositions according to the invention of this embodiment are therefore characterized in that they are used as derivatives of the 3-hydroxy-4 (1H) -pyridone of the general formula (I)

and or

and or

contain.

In a particularly preferred embodiment, the compositions according to the invention comprise a compound or a mixture of various compounds from the group of the derivative (e) of the 3-hydroxy-4 (1H) -pyridone of the general formula (I) from 0.00001 to 10% by weight. -% preferably from 0.0001 to 5 wt .-%, particularly preferably from 0.001 to 1 wt .-%, each based on the total composition.

Particularly preferred deodorant or antiperspirant compositions according to the invention contain, based on their weight, 0.00001 to 10% by weight, preferably 0.0001 to 5% by weight, particularly preferably 0.0005 to 2.5% by weight. , Further preferably 0.001 to 1 wt .-% and in particular 0.01 to 0.5 wt .-% derivative (s) of the 3-hydroxy-4 (1 H) -pyridone of the general formula (I).

Among the above compounds, some are most preferred. According to further preferred deodorant or antiperspirant compositions contain - based on the weight of the ready-to-use composition - 0.00001 to 10 wt .-%, preferably 0.0001 to 5 wt .-%, particularly preferably 0.0005 to 2.5 wt .-%, more preferably 0.001 to 1 wt .-% and in particular 0.01 to 0.5 wt .-% of one or more compounds from the group

3-hydroxy-1- (2-hydroxyethyl) -2-methylpyridine-4 (1H) -one

3-hydroxypropyl (1-hydroxy) -1- (3-hydroxypropyl) -2-methylpyrazine-4 (1H) -one

- 3-hydroxy-1- (4-hydroxybutyryl) -2-methylpyran-4-one (1H) -one

3-hydroxy-1- (2-methoxyethyl) -2-methylpyridine-4 (1H) -one

1- (2-ethoxyethyl) -3-hydroxy-2-methylpyridine-4 (1H) -one

3-hydroxy-1- (3-methoxypropyl) -2-methylpyridine-4 (1H) -one

1- (3-ethoxypropyl) -3-hydroxy-2-methylpyridine-4 (1H) -one

- (3-hydroxy-2-methyl-4-oxopyridine-1 (4H) -yl) acetonitrile

- 3- (3-hydroxy-2-methyl-4-oxopyridin-1 (4H) -yl) -propanenitrile

1- [2- (dimethylamino) ethyl] -3-hydroxy-2-methylpyridine-4 (1H) -one

1- [3- (dimethylamino) propyl] -3-hydroxy-2-methylpyridine-4 (1H) -one

1- [2- (diethylamino) ethyl] -3-hydroxy-2-methylpyridin-4 (1H) -one

1- [3- (Diethylamino) propyl] -3-hydroxy-2-methylpyridine-4 (1H) -one

3-Hydroxy-1- [2- (1H -imidazol-1-yl) ethyl] -2-methyl-pyridin-4 (1H) -one

3-Hydroxy-1- [3- (1 H -imidazol-1-yl) propyl] -2-methylpyridin-4 (1 H) -one.

In summary, according to the invention, preferred deodorant or antiperspirant compositions contain, based on their weight, from 0.00001 to 10% by weight, preferably from 0.0001 to 5% by weight, particularly preferably from 0.0005 to 2.5% by weight. , more preferably 0.001 to 1 wt .-% and in particular 0.01 to 0.5 wt .-% derivative (s) of the 3-hydroxy-4 (1 H) -pyridone of the general formula (I)

in which

the radical R 1 is a C | -C ₆ alkyl group, a C ₂ -C ₆ alkenyl group, a C ₂ -C ₆ hydroxyalkyl group, a C ₂ -C ₆ polyhydroxyalkyl group, a Ci-C6-alkoxy C ₂ -C ₆ alkyl group, a C ₁ -C ₆ cyanoalkyl group, an amino C ₂ -C ₆ alkyl group, a di (C ₁ -C ₆ alkyl) aminoC ₂ -C ₆ alkyl group, an aryl group , an aryl-Ci-C6-alkyl group, a heteroaryl group or a heteroaryl-C -Cö-alkyl group or one of the following structural units (2) to (10)

where n stands for a natural number of 2 to 6 in this context,

C 1 -C ₆ -alkyl group, a C ₂ -C ₆ -hydroxyalkyl group or a hydroxy group,

As an alternative or additional hair growth-inhibiting ingredient, the agents according to the invention may contain so-called AGEs.

The term AGE comes from the English term "advanced glycation endproducts". For the purposes of the present invention, AGEs are obtainable, for example, according to the following (exemplary) reaction equation:

(I) (I I) (H l) (IV)

Advantageous for the purposes of the present invention, in addition to the actual AGEs and their precursors, such as. Amadori or Maillard products (corresponding to (III) in the above reaction equation) or so-called EGEs (Early Glycation End Products), which are obtainable, for example, as intermediates in the rearrangement of Amadori products (III) to AGEs (IV).

Further products of the Maillard reaction, in particular those which are also derived from Amadoriprodukt, in particular maltol (Larixin, 3-hydroxy-2-methyl-4H-pyran-4-one) and 4-hydroxy-2,5-dimethyl-3 (2H) -furanone (Furaneol®) may also be included within the term "precursor".

For the purposes of the present invention, the term "precursor" expressly does not mean the respective starting materials of the reaction, ie the unreacted starting materials.

Advantageous starting materials (I) carry an aldehyde group (CHO) and are chosen, for example, from the group of sugars (aldoses, eg trioses, tetroses, pentoses, hexoses and the like, such as glucose, galactose, mannose, etc.). Advantageous starting materials (II) have a free amino group and are selected, for example, from the group of amino acids and the group of peptides having terminal amino groups, in particular lysine, hydroxylysine, arginine, tryptophan and histidine are advantageous. Further advantageously, the free amino group can also originate from N-terminal ends of proteins and peptides, and also advantageously sphingosine and dihydrosphingosine and their homologs with different lengths of (unsaturated) acyl radicals.

AGEs according to the invention preferably contain at least one nitrogen-containing and / or oxygen-containing five-membered and / or six-membered ring.

Advantageous in the context of the present invention are, for example, the furan derivatives FFI and the furanone 2, which are distinguished by the following structural formulas:

Further preferred is the so-called AFGP of Structural Formula 3:

Further preferred are pyrralines, for example those of structural formula 4:

Further preferred are pyranopyranones, for example those of structural formula 5:

Further preferred are pyrrolinones, for example those of the following structural formulas:

According to the invention, the radical R in the structural formulas 1, 3 and 4 preferably originates from proteins and peptides; Accordingly, these are preferably peptide, amino acid or protein residues which may be attached terminally or laterally to the nitrogen atom.

R is further advantageously selected from the group of saturated or unsaturated, branched or unbranched alkyl groups having 1 to 35 carbon atoms.

Also advantageous for the purposes of the present invention is pentosidine (formula 10):

Also particularly preferred is the so-called A2E (Formula 1 1):

11

The illustrated structural formulas are not intended to limit the invention to certain isomers of the substances according to the invention. Rather, not shown isomers or isomer mixtures are advantageous in the context of the present invention. Further preferred advanced glycation end products (AGEs) and / or their precursors are obtained by the reaction of an amino acid selected from lysine, hydroxylysine, arginine, tryptophan and / or histidine.

Other preferred Advanced Glycation End Products (AGEs) and / or their precursors are obtained by the reaction of an aldose, preferably selected from glucose, lactose, galactose and / or mannose.

According deodorant or antiperspirant compositions according to the invention are characterized in that the compound from the group of advanced glycation end products (AGEs) and / or their precursors is selected from reaction products of the reaction of at least one compound from the group of sugars, preferably selected from the aldoses , preferably selected from glucose, lactose, galactose and / or mannose, with at least one compound from the group of amino acids, preferably selected from lysine, hydroxylysine, arginine, tryptophan and / or histidine.

Preferred lysine-based AGEs of the invention and / or their precursors are furthermore products of the Maillard reaction of lysine A with sugars, examples of such substances according to the invention are Ν-ε-fructosyllysine (fructoselysine) 12, Ν-ε-carboxymethyllysine (CML) 13, carboxyethyl lysine (CEL) 14 or maltosine 15 and pyridosine 15a, which are characterized by the following structural formulas:

Further preferred arginine-based AGEs according to the invention are products of the Maillard reaction of arginine B with sugars; examples of such substances according to the invention are ornithinoimidazolinone 16, argpyrimidine 17, 3-deoxyglucosululose (3-DG) 18 or galactosylisomaltol 19, which can be mentioned characterized by the following structural formulas:

Also advantageous for the purposes of the present invention are glycation products of lysine and arginine, for example CML 20, CEL 21, pyrraline 22, DOLD 23, GOLD 24, MOLD 25, pentosidine 26, dihydroxyimidazolidine 27, glarg 28, CMA 29, imidazolone 30, MGO-imidazolone 31, 3-DG-imidazolone 32 or argopyrimidine 33, which are characterized by the following structural formulas:

In summary, deodorant or antiperspirant compositions according to the invention are preferred which contain at least one compound according to formula 2 to 33 inclusive 15a. Particularly preferred deodorant or antiperspirant compositions according to the invention comprise - based on their weight - 0.00001 to 5 wt .-%, preferably 0.0001 to 3 wt .-%, particularly preferably 0.001 to 2 wt .-%, more preferably 0 , 01 to 1 wt .-% and in particular 0, 1 to 0.5 wt .-% Advanced Glycation End Products (AGEs) and / or their precursors.

A particularly preferred AGE is maltosine, which is particularly advantageously included in compositions of the invention. According to the invention, extremely preferred deodorant or antiperspirant compositions contain, based on their weight, from 0.0001 to 5% by weight, preferably from 0.001 to 3% by weight, particularly preferably from 0.01 to 2% by weight preferably 0.1 to 1 wt .-% and in particular 0.25 to 0.5 wt .-% maltosine (formulas 15 / 15a).

Further preferred embodiments of the invention are characterized in that the cosmetically or dermatologically acceptable carrier is present as powder, in stick form, as aerosol spray, pump spray, liquid or gel-like roll-on application, cream, lotion, solution, gel or applied to a substrate.

Deodorant or antiperspirant sticks can be in gelled form, on an anhydrous basis, based on a W / O emulsion, based on an O / W emulsion, based on a water-oil multiple emulsion, based on a nanoemulsion and are based on a microemulsion, wherein the oil phase contain at least one silicone component or can consist of at least one silicone component. Furthermore, the compositions according to the invention, which are formulated as deodorant or antiperspirant sticks, can be prepared on anhydrous fat basis, based on a polyol-in-oil emulsion based on an oil-in-polyol emulsion based on a polyol oil. Multiple emulsion, based on a nanoemulsion and based on a microemulsion, wherein the polyol phase may be anhydrous or may have only a low water content. Gel sticks can be prepared on the basis of fatty acid soaps, dibenzylidenesorbitol, N-acylamino acid amides, 12-hydroxystearic acid, polyamides, polyamide derivatives, polysaccharides such as xanthan, polyglucomanna- NEN, guar, Konjak, celluloses or starches, polyacrylates, polyacrylate derivatives and other gelling agents are formulated.

Aerosol sprays, pump sprays, roll-on applications and creams may be in the form of a water-in-oil emulsion, oil-in-water emulsion, silicone oil-in-water emulsion, water-in-oil microemulsion, oil-in Water-microemulsion, silicone oil-in-water microemulsion, polyol-in-oil emulsion, oil-in-polyol emulsion, polyol-oil multiple emulsion, anhydrous suspension, preferably anhydrous oil-based suspension, alcoholic solution, in particular ethanolic solution, hydroalcoholic solution, in particular solutions with more than 50 wt .-% of a water-ethanol mixture, glycolic solution, especially as a solution in propylene glycol, glycerol, dipropylene glycol and (under normal conditions) liquid polyethylene glycols, hydroglycolic solution, polyol solution , Water-polyol solution, aqueous gel, lipogel, and oil. All the above-mentioned compositions may be thickened, for example based on fatty acid soaps, dibenzylidenesorbitol, N-acylamino acid amides, 12-hydroxystearic acid, carbomer-type polyacrylates, polyacrylamides and polysaccharides, which may be chemically and / or physically modified. The compositions may be transparent, translucent or opaque. If the compositions according to the invention are in the form of a stick, they preferably contain a lipid or wax matrix comprising at least one lipid or wax component with a melting point> 50 ° C.

The compositions according to the invention which are formulated as an emulsion, in particular as an oil-in-water or polyol-in-water emulsion, preferably comprise at least one nonionic oil-in-water emulsifier having an HLB value of more than 7 These are emulsifiers which are generally known to the person skilled in the art and are listed, for example, in Kirk-Othmer, "Encyclopedia of Chemical Technology", 3rd edition, 1979, Volume 8, pages 913-916. Particularly preferred deodorant or antiperspirant compositions according to the invention comprise at least one nonionic oil-in-water emulsifier in a total amount of 0.5-10% by weight, more preferably 1-4% by weight and most preferably 1, 5 - 3 wt .-%, each based on the total composition.

Preferred compositions according to the invention, which are formulated as an emulsion or stick, preferably furthermore comprise at least one nonionic water-in-oil emulsifier having an HLB value greater than 1.0, and less than or equal to 7.0, selected from the mono- and diesters of Ethylene glycol and the mono-, di-, tri- and tetra-esters of pentaerythritol with linear saturated fatty acids having 12-30, in particular 14-22 carbon atoms, which may be hydroxylated, and mixtures thereof, as consistency regulator and / or water binder. According to the invention, the mono- and diesters are preferred. According to the invention, preferred C ₁₂ -C ₃ o-fatty acid radicals are selected from lauric acid, myristic acid, palmitic acid, stearic acid, and behenic acid Arachinsäure- radicals; particularly preferred is the stearic acid residue.

Preferred as additional water-in-oil emulsifier are:

linear saturated alkanols having 12 to 30 carbon atoms, in particular 16 to 22 carbon atoms, in particular cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol and Lanolin alcohol or mixtures of these alcohols, as obtainable in the industrial hydrogenation of vegetable and animal fatty acids,

Esters and in particular partial esters of a polyol having 3 to 6 C atoms and linear saturated and unsaturated fatty acids having 12 to 30, in particular 14 to 22, C atoms which may be hydroxylated. Such esters or partial esters are, for. The monoesters and diesters of glycerol or the monoesters of propylene glycol with linear saturated and unsaturated C 12 -C ₃₀ carboxylic acids which may be hydroxylated, in particular those with palmitic and stearic acid, the sorbitan mono-, di- or triesters of linear saturated and unsaturated d ₂ -C ₃₀ -carboxylic acids which may be hydroxylated, in particular those of myristic acid, palmitic acid, stearic acid or of mixtures of these fatty acids and the methylglucose mono- and diesters of linear saturated and unsaturated C ₁₂ -C ₃₀ - Carboxylic acids which may be hydroxylated;

Sterols, ie steroids which carry a hydroxyl group at the C3 atom of the steroid skeleton and both from animal tissue (zoosterols, eg cholesterol, lanosterol) as well as from plants (phytosterols, eg ergosterol, stigmasterol, sitosterol) and from fungi and yeasts (mycosterols) which may be low ethoxylated (1-5 EO);

Alkanols and carboxylic acids each having 8-24 C atoms, in particular having 16-22 C atoms, in the alkyl group and 1-4 ethylene oxide units per molecule which have an HLB value of greater than 1.0, and less than or equal to 7.0 exhibit,

Glycerol monoethers of saturated and / or unsaturated, branched and / or unbranched alcohols of a chain length of 8-30, in particular 12-18 carbon atoms.

Partial esters of polyglycerols with n = 2 to 10 glycerol units and with 1 to 5 saturated or unsaturated, linear or branched, optionally hydroxylated C ₈ - C ₃₀ fatty acid residues esterified, if they have an HLB value of less than or equal to 7,

and mixtures of the aforementioned substances.

According to the invention, it may be preferable to use only a single additional water-in-oil emulsifier. In another preferred embodiment, the compositions according to the invention comprise mixtures, in particular technical mixtures, of at least two additional water-in-oil emulsifiers.

Particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that at least one water-in-oil emulsifier is present in a total amount of 0.1-15% by weight, preferably 0.5-8.0% by weight, and particularly preferably 1 to 4% by weight, based on the total composition, are contained. Furthermore, amounts of from 2 to 3% by weight, based on the total weight of the composition, according to the invention may also be extremely preferred.

Further preferred compositions according to the invention are characterized in that the total content of nonionic and ionic emulsifiers and / or surfactants with an HLB value above 8 not more than 20 wt .-%, preferably at most 15 wt .-%, particularly preferably at most 10 wt .-% , more preferably at most 7 wt .-%, further particularly preferred not more than 4% by weight and, most preferably, not more than 3% by weight, based in each case on the total composition according to the invention.

Preferred compositions of the present invention, which are in the form of an emulsion, suspension or stick, preferably further contain at least one oil which is liquid at 20 ° C and which is not a perfume component and does not constitute an essential oil. According to the invention preferred oils are selected from branched, saturated or unsaturated fatty alcohols having 6 - 30 carbon atoms, the triglycerides of linear or branched, saturated or unsaturated, optionally hydroxylated C ₈ -3o fatty acids, dicarboxylic acid esters of linear or branched C ₂ -C ₀ - alkanols , the addition products of 1 to 5 propylene oxide units of mono- or polyhydric C ₈ _22 alkanols such as octanol, decanol, decanediol, lauryl alcohol, myristyl alcohol and stearyl alcohol, eg. PPG-2-myristyl ethers and PPG-3-myristyl ethers, the esters of linear or branched saturated or unsaturated fatty alcohols having from 2 to 30 carbon atoms with linear or branched saturated or unsaturated fatty acids having from 2 to 30 carbon atoms which may be hydroxylated, in particular hexyldecyl stearate Hexyldecyl laurate, isodecyl neopentanoate, isononyl isononanoate, 2-ethylhexyl palmitate and 2-ethylhexyl stearate; the addition products of at least 6 ethylene oxide and / or propylene oxide units of mono- or polyhydric C ₃ -22-alkanols such as butanol, butanediol, myristyl alcohol and stearyl alcohol, eg. PPG-14-butyl ether, PPG-9-butyl ether, PPG-10-butanediol and PPG-15 stearyl ether; the C ₈ -C ₂₂ -fatty alcohol esters of monohydric or polyhydric C ₂ -C ₇ -hydroxycarboxylic acids, in particular the esters of glycolic acid, lactic acid, malic acid, tartaric acid, citric acid and salicylic acid; the symmetrical, asymmetrical or cyclic esters of carbonic acid with fatty alcohols, eg. Eg dicopyryl carbonate; the esters of dimers of unsaturated C ₂ -C ₂ 2 -fatty acids (dimer fatty acids) with monovalent linear, branched or cyclic C ₂ -C ₈ -alkanols or with polyvalent linear or branched C ₂ -C ₆ -alkanols. It may be extraordinarily preferred according to the invention to use mixtures of the abovementioned oils. Further oil components preferred according to the invention are selected from silicone oils and hydrocarbon oils.

Particularly preferred compositions according to the invention, which are formulated as a water-in-oil emulsion, preferably further comprise at least one water-in-oil emulsifier. The at least one water-in-oil emulsifier is preferably in an amount of 0.5 to 5 wt .-%, particularly preferably 1, 0 to 1, 5 to 2.5 wt .-%, each based on the total weight of Emulsion, included.

A particularly preferred group of water-in-oil emulsifiers according to the invention are the poly (C ₂ -C ₃ ) alkylene glycol-modified silicones whose previous INCI name was Dimethicone Copolyol, with the current INCI names PEG-x Dimethicone (with x = 2-20, preferably 3-17, more preferably 1-1-12), bis-PEG-y dimethicones (with y = 3-25, preferably 4-20), PEG / PPG a / b dimethicones (where a and b independently of one another represent numbers from 2 to 30, preferably 3 to 30 and particularly preferably 12 to 20, in particular 14 to 18,), bis-PEG / PPG-c / d dimethicones (where c and d independently of one another represent numbers of 10 25, preferably 14-20 and more preferably 14-16) and bis-PEG / PPG-e / f PEG / PPG g / h Dimethicones (wherein e, f, g and h independently of one another represent numbers of 10-20, preferably 14-18 and more preferably 16). Particular preference is given to PEG / PPG-18/18 dimethicones, which are commercially available in a 1: 9 mixture with cyclomethicone as DC 3225 C or DC 5225 C, PEG / PPG-4/12 dimethicone, sold under the name Abil B 8852 is available as well as Bis-PEG / PPG-14/14 Dimethicone, which is commercially available in a mixture with Cyclomethicone as Abil EM 97 (Evonik), Bis-PEG / PPG-20/20 Dimethicone, under the name Abil B 8832 is available, PEG / PPG-5/3 trisiloxanes (Silsoft 305), and PEG / PPG-20/23 dimethicones (Silsoft 430 and Silsoft 440). Further according to the invention preferred W / O emulsifiers are poly (C ₂ -C ₃₎ alkylene glycol-modified silicones, the ₄ -C ₈ alkyl groups are hydrophobically modified with C, more preferably cetyl PEG / PPG-10/1 Dimethicone (formerly Cetyl dimethicone copolyol, available as Abil EM 90 or in a mixture of polyglyceryl-4-isostearate, cetyl PEG / PPG-10/1 dimethicone and hexyl laurate under the trade name Abil WE 09), furthermore alkyl methicone copolyols and alkyl dimethicone ethoxy glucosides.

Particularly preferred compositions according to the invention, which are formulated as a propellant-driven aerosol, contain at least one propellant. Preferred propellants (propellants) are propane, propene, n-butane, isobutane, isobutene, n-pentane, pentene, isopentane, isopentene, methane, ethane, dimethyl ether, nitrogen, air, oxygen, nitrous oxide, 1, 1, 1, 3-tetrafluoroethane, heptafluoro-n-propane, perfluoroethane, monochlorodifluoromethane, 1, 1-difluoroethane, both individually and in combination. Also hydrophilic propellants, such. As carbon dioxide, can be used advantageously in the context of the present invention, when the proportion of hydrophilic gases is selected low and lipophilic propellant gas (eg., Propane / butane) is present in excess. Particularly preferred are propane, n-butane, isobutane and mixtures of these propellants. It has been found that the use of n-butane as the only propellant gas according to the invention can be particularly preferred. The amount of blowing agent is preferably 20-80% by weight, more preferably 30-70% by weight and most preferably 40-50% by weight, based in each case on the total weight of the preparation, consisting of the composition according to the invention and the blowing agent.

Preferred compositions according to the invention also comprise at least one water-soluble polyhydric C ₂ -C ₉ -alkanol having 2-6 hydroxyl groups and / or at least one water-soluble polyethylene glycol having 3-20 ethylene oxide units and mixtures thereof. Surprisingly, it has been found that such compounds can further support the anti-irritative and soothing effect of the compositions according to the invention. These components are preferably selected from 1,2-propylene glycol, 2-methyl-1,3-propanediol, glycerol, 1,2-butylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, 1,2-pentanediol, 1, 5-pentanediol, 1, 2-hexanediol, 1, 6-hexanediol, 1, 2,6-hexanetriol, 1, 2-octanediol, 1, 8-octanediol, dipropylene glycol, tripropylene glycol, diglycerol, triglycerol, erythritol, sorbitol and mixtures of aforementioned substances. Preferred water-soluble polyethylene glycols are selected from PEG-3, PEG-4, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18 and PEG-20 and mixtures thereof, with PEG-3 to PEG-8 being preferred. preferred deodorant or antiperspirant compositions according to the invention comprise at least one water-soluble polyhydric C ₂ -C ₉ -alkanol having 2 to 6 hydroxyl groups and / or at least one water-soluble polyethylene glycol having 3 to 20 ethylene oxide units, selected from 1,2-propylene glycol, 2 -Methyl-1,3-propanediol, glycerol, 1,2-butylene glycol, 1,3-butylene glycol and 1,4-butylene glycol, 1,2-pentanediol, 1,5-pentanediol, 1,2-hexanediol, 1,6 -Hexanediol, 1, 2,6-hexanetriol, 1, 2-octanediol, 1, 8-octanediol, dipropylene glycol, tripropylene glycol, diglycerol, triglycerol, erythritol, sorbitol, and mixtures of the aforementioned substances. 1, 2-Propylene glycol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 6-hexanediol, 1, 2-octanediol, dipropylene glycol, tripropylene glycol and mixtures thereof are particularly preferred. Particularly preferred deodorant or antiperspirant compositions according to the invention comprise the at least one water-soluble polyhydric C ₂ -C ₉ -alkanol with 2-6 hydroxyl groups and / or the at least one water-soluble polyethylene glycol with 3-20 ethylene oxide units in total in amounts of 3-30% by weight .-%, preferably 8 - 25 wt .-%, particularly preferably 10 - 18 wt .-%, each based on the total composition.

Preferred compositions according to the invention contain water. The proportion of water is preferably 0, 1-99 wt .-%, particularly preferably 3 to 80 wt .-%, most preferably 10 to 70 wt .-%, further preferably 15 - 60 wt .-%, 20 - 50 wt .-%, 30- 40 wt .-%, each based on the total composition.

Particularly preferred deodorant or antiperspirant compositions according to the invention are characterized in that furthermore at least one perfume component is contained. As perfume component perfumes, perfume oils or perfume oil ingredients can be used. Perfume oils or fragrances can according to the invention individual fragrance compounds, eg. As the synthetic products of the ester type, ethers, aldehydes, ketones, alcohols and hydrocarbons. Fragrance compounds of the ester type are known e.g. Benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzylcarbinylacetate (DMBCA), phenylethylacetate, benzylacetate, ethylmethylphenylglycinate, allylcyclohexylpropionate, styrallylpropionate, benzylsalicylate, cyclohexylsalicylate, floramate, melusate and jasmecyclate. The ethers include, for example, benzyl ethyl ether and ambroxane, to the aldehydes e.g. the linear alkanals having 8-18 C atoms, citral, citronellal, citronellyloxy-acetaldehyde, cyclamen aldehyde, lilial and bourgeonal, to the ketones, e.g. the ionones, alpha-isomethylionone and methylcedryl ketone; the alcohols anethole, citronellol, eugenol, geraniol, linalool, phenylethyl alcohol and terpineol; the hydrocarbons mainly include the terpenes such as limonene and pinene. Particularly preferred deodorant or antiperspirant compositions according to the invention contain at least one perfume component in a total amount of 0.00001 to 10 wt .-%, preferably 0.5 to 7 wt .-%, particularly preferably 1-5 wt .-%, each based on the overall composition.

Further objects, as mentioned above, are a non-therapeutic, cosmetic method for regulating hair growth, in particular for reducing hair growth, wherein a deodorant or antiperspirant composition according to the invention is topically applied in an effective amount is applied to the skin, in particular to the skin in the underarm area, and a non-therapeutic, cosmetic process for the treatment of body odor, in which a composition according to the invention is applied in an effective amount to the skin.

Another object of the present application is the use of a deodorant or antiperspirant composition according to the invention or preferred according to the invention for improving the skin compatibility in the non-therapeutic, cosmetic treatment of body odor and / or in the non-therapeutic, cosmetic regulation of hair growth.

With regard to preferred embodiments of the method according to the invention, what has been said about the compositions according to the invention applies mutatis mutandis.

The following examples show compositions according to the invention. All quantities are in wt .-%.

Antiperspirant wax sticks

Antiperspirant wax sticks

2.1 2.2

Hexyldecanol 10,00 12,00

PPG-14 butyl ether 6.00 5.00

Hydrogenated Castor Oil 4.00 5.00

Stearyl alcohol 12.00 14.00

Cetyl alcohol 6.00 5.00

PEG-20 glyceryl stearate 5.00 4.00 Ceteareth-30 3,00 1, 00

Perfume 1, 00 1, 20 frans-4-ferf-butyl-cyclohexanol 0, 10 0.2

1, 2-pentanediol 1, 0 2.0

Perlite 1, 0 -

Silver sulfate - 0.0015

Tale 8.0 5.0

Cyclopentasiloxane ad 100 ad 100

Anhydrous antiperspirant wax pencils without Cyclomethicone

3.1 3.2

Stearyl Alcohol 16 18

Behenyl Alcohol 0.2 -

Ceteareth-30 3 3

PPG-14 butyl ether 15 5

Cocoglycerides (FP 30-32 ° C) 5 4

Hydrogenated Castor Oil 1, 5 1, 5

Aluminum Chlorohydrate 20 20

Tale 5 3

Perfume 1 1 frans-4-ferf-butyl-cyclohexanol 0.20 0.5

1, 2-pentanediol 4.0 5.0

Silver Citrate 1, 0 -

Maltos in 0.5

Dimethicone (2 cSt) - ad 100

Dimethicone (5 cSt) ad 100 -

Antiperspirant Cream Anhydrous (Soft Solid)

4.1 4.2

Aluminum chlorohydrate 20.00 22.00

Hexyldecanol 5.00 4.50

Dicaprylyl ether 3.00 4.00

Cocoglycerides 5.00 6.00

C18-C36 triglycerides 6.00 5.00

Ceteareth-30 3.00 2.00

PEG-20 glyceryl stearate 5.00 6.00

Cellulose 3.00 2.00

Aluminum Starch Octenylsuccinate 5.00 4.00

Silica 1, 00 2.00

Tale 10.00 5.00

Perfume 1, 00 1, 50 frans-4-ferf-butyl-cyclohexanol 0, 10 0.2

1, 2-pentanediol 1, 0 2.0

Zeolite 0.4 -

Silver citrate - 0.002

Cyclopentasiloxane ad 100 ad 100 Dibenzylidene sorbitol-based antiperspirant gel sticks

Suspensions for spraying as an antiperspirant spray

7.1 7.2

Perfume 5.00 5.00

Aluminum chlorohydrate (activated) 32.00 28.00

Disteardimonium hectorite 4,50 3,90

Propylene carbonate 1, 50 1, 30 frans-4-tert-butyl-cyclohexanol

0.05 0.1

1, 2-pentanediol

0.3 1, 0

Silver lactate 0.0012 -

Alum - 0.2

Ethylhexyl palmitate ad 100 25.00

C10-13 isoparaffin - ad 100

Compositions 7.1 and 7.2 were filled in spray cans of internally painted aluminum and mixed with an isobutane / butane / propane propellant mixture in the weight ratio suspension: propellant of 25:75, 22:78, 20:80, 18:82, 15:85 and 13: 87.

Suspensions for spraying as a deodorant spray

The compositions 8.2 and 8.2 according to the invention were filled into spray cans of aluminum painted on the inside and mixed with an isobutane / butane / propane blowing agent mixture in the weight ratio suspension: propellant of 25:75, 22:78, 20:80, 18:82, 15: 85 and 13: 87 charged.

Water-in-oil emulsion for administration as a spray (with propellant) (in% by weight)

9.1

Aluminum chlorohydrate 33

Cio-Ci ₃ -Isoalkane 8.9

PEG / PPG-18/18 Dimethicone 1, 4

Isoceteth-20 0.5

Dimethicone (5 cSt) 4.2

Isopropyl myristate 9.0

1, 2-pentanediol 5.0 1,4-dimethylolcyclohexane 4.0

Phenoxyethanol 0.50

frans-4-ferf-butyl-cyclohexanol 1, 0

KAI (S0 ₄ ) ₂ ^■ 12 H ₂ 0 0,5

Perfume 2.5

Water ad 100

15 parts by weight of the antiperspirant water-in-oil emulsion 9.1 are filled together with 85 parts by weight of E-CF ₃ CH = CHF in a spray can.

Deodorant foam

Stick compositions according to the invention

INCI No. 1 1.1 No. 1 1.2 No. 1 1.3

Cutina AGS Glycol Distearate 2,4 2,4 2,4

Cutina FS45 Palmitic Acid, Stearic Acid 3,5 3,5 3,5

Eumulgin B2 CETEARETH-20 0.75 0.75 0.75

Eumulgin B3 CETEARETH-30 0.75 0.75 0.75

Ceraphyl 230 DIISOPROPYL ADIPATE 5,7 5,7 5,7

Novata AB COCOGLYCERIDES 4 4 4

Cutina CP CETYL PALMITATE 5 5 5

Cutina HR Hydrogenated Castor Oil 4 4 4

Kester Wax K62 CETEARYL BEHENATE 5 5 5

Aluminum Chlorohydrate 20 20 20

Talc TALC 10 10 10 kappa carrageenan 0.5 - - Apple pectin 1.0 -

Strength - 0.2

Perfume PERFUME 1.1 1.1 1.1 frans-4-ferf-butyl-cyclohexanol 0.5 0.1 0.6

Isopropyl alcohol 0.3 0.3 0.3

1,2-pentanediol PENTYLENE GLYCOL 10 10 10

Silver citrate 0.0015 - -

Perlite - 0.6 -

3-hydroxy-2-methyl-1 - -

propylpyridine-4 (1H) -one 0.4

Water (fully demineralized) AQUA (WATER) ad 100.00 ad 100.00 ad 100.00

Claims

claims

1) Cosmetic or dermatological deodorant or antiperspirant composition comprising in a cosmetically or dermatologically acceptable carrier

a) at least one deodorant or antiperspirant active ingredient,

b) frans-4-ferf-butyl-cyclohexanol,

c) at least one deodorant adjuvant from the groups of

i. Silver salts and / or

ii. Silver complexes and / or

iii. Minerals of volcanic origin and / or

iv. Zeolites and / or

v. Alum and / or

vi. Hair growth inhibiting agents.

2) deodorant or antiperspirant composition according to claim 1, characterized in that it comprises at least one antiperspirant active ingredient in a total amount of 3 - 25 wt .-%, preferably 5 - 22 wt .-% and in particular 10 - 20 wt. %, based on the total weight of the active substance in the total composition.

3) deodorant or antiperspirant composition according to any one of claims 1 or 2, characterized in that it comprises at least one deodorant active ingredient in a total amount of 0, 1 - 10 wt .-%, preferably 0.2 - 7 wt .-% , Particularly preferably 0.3 to 5 wt .-% and most preferably 0.4 to 1, 0 wt .-%, each based on the total weight of the active substance of the deodorant active ingredient or the deodorant active ingredients in the overall composition contains.

4) deodorant or antiperspirant composition according to one of claims 1 to 3, characterized in that it - based on their weight - 0.05 to 10 wt .-%, preferably 0, 1 to 7.5 wt .-%, further preferably 0.25 to 5 wt .-%, particularly preferably 0.5 to 2.5 and in particular 0.6 to 1, 25 wt .-% frans-4-ferf-butyl-cyclohexanol.

5) deodorant or antiperspirant composition according to one of claims 1 to 4, characterized in that they - based on their weight - silver ions in a total amount of 1-100 ppm, preferably 2-50 ppm, more preferably 5-20 ppm, extremely preferably 7-10 ppm, in each case based on the weight of the composition according to the invention.

6) deodorant or antiperspirant composition according to one of claims 1 to 5, characterized in that it - based on their weight - 0.05 to 15 wt .-%, preferably 0, 1 to 12.5 wt .-%, more preferably 0.25 to 10 wt .-%, particularly preferably 0.5 to 7.5 and in particular 0.6 to 5 wt .-% minerals of volcanic origin, in particular Perlite, contains.

Deodorant or antiperspirant composition according to one of Claims 1 to 6, characterized in that it contains, by weight, 0.05 to 15% by weight, preferably 0 to 1 to 10% by weight, more preferably 0, 25 to 5 wt .-%, particularly preferably 0.5 to 2 and in particular 0.6 to 1 wt .-% zeolites.

Deodorant or antiperspirant composition according to one of Claims 1 to 7, characterized in that it contains, by weight, from 0.05 to 10% by weight, preferably from 0 to 1 to 5% by weight, more preferably 0, 2 to 3 wt .-%, particularly preferably 0.5 to 2 and in particular 0.7 to 1 wt .-% alum (s).

Deodorant or antiperspirant composition according to any one of claims 1 to 8, characterized in that it contains, based on the weight of the ready-to-use composition, from 0.00001 to 10% by weight, preferably 0.0001 to 5% by weight preferably 0.0005 to 2.5 wt .-%, more preferably 0.001 to 1 wt .-% and in particular 0.01 to 0.5 wt .-% derivative (s) of the 3-hydroxy-4 (1 H) - pyridone of the general formula (I) contains

in which

the radical R 1 _ö a Ci-C alkyl group, a C ₂ -C ₆ alkenyl group, a C ₂ -C ₆ - hydroxyalkyl group, a C ₂ -C ₆ polyhydroxyalkyl group, a C-RC6-alkoxy-C ₂ -C ₆ -alkyl group, a C 1 -C ₆ cyanoalkyl group, an amino C ₂ -C ₆ alkyl group, a di- (C 1 -C ₆ alkyl) aminoC ₂ -C ₆ alkyl group, an aryl group , an aryl-C 1 -C ₆ -alkyl group, a heteroaryl group or a heteroaryl-C ₁ -C ₆ -alkyl group or one of the following structural units (2) to (10)

in this context, for a natural number of 2 to 6 wherein n is, the two radicals R2 and R3 are independently a hydrogen atom, a Ci-C _ö alkyl group, a C ₂ -C ₆ hydroxyalkyl group or a hydroxy group,

10) deodorant or antiperspirant composition according to any one of claims 1 to 9, characterized in that it - based on their weight - 0.00001 to 15 wt .-%, preferably 0.0001 to 10 wt .-%, particularly preferably 0.001 to 5 wt .-%, more preferably 0.01 to 4 wt .-% and in particular 0, 1 to 2 wt .-% advanced glycation end products (AGEs) and / or their precursors.

1 1) deodorant or antiperspirant composition according to one of claims 1 to 10, characterized in that it comprises at least one water-soluble polyhydric C ₂ - C ₉ - alkanol having 2 - 6 hydroxyl groups selected from 1, 2-propylene glycol, 1, 2 Pentanediol, 1,2-hexanediol, 1,6-hexanediol, 1,2-octanediol, dipropylene glycol, tripropylene glycol and mixtures thereof.

12) Non-therapeutic, cosmetic process for the treatment of body odor, in which a deodorant or antiperspirant composition according to any one of claims 1 to 10 is applied in an effective amount to the skin. 13) Use of a deodorant or antiperspirant composition according to any one of claims 1 to 10 for improving the skin compatibility in the non-therapeutic, cosmetic treatment of body odor and / or in the non-therapeutic, cosmetic regulation of hair growth.