WO2011112070A2 - A composition to boost and enhance immune system and method of preparing thereof - Google Patents
A composition to boost and enhance immune system and method of preparing thereof Download PDFInfo
- Publication number
- WO2011112070A2 WO2011112070A2 PCT/MY2011/000015 MY2011000015W WO2011112070A2 WO 2011112070 A2 WO2011112070 A2 WO 2011112070A2 MY 2011000015 W MY2011000015 W MY 2011000015W WO 2011112070 A2 WO2011112070 A2 WO 2011112070A2
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- WO
- WIPO (PCT)
- Prior art keywords
- composition
- subjecting
- raw materials
- feonum
- immune system
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 68
- 210000000987 immune system Anatomy 0.000 title claims abstract description 16
- 238000000034 method Methods 0.000 title claims description 64
- 239000000843 powder Substances 0.000 claims abstract description 10
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- 239000002994 raw material Substances 0.000 claims description 28
- 240000002234 Allium sativum Species 0.000 claims description 17
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- 238000001035 drying Methods 0.000 claims description 15
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- 244000273928 Zingiber officinale Species 0.000 claims description 12
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- 241001280436 Allium schoenoprasum Species 0.000 description 1
- 235000001270 Allium sibiricum Nutrition 0.000 description 1
- 244000037185 Cinnamomum burmannii Species 0.000 description 1
- 235000014487 Cinnamomum burmannii Nutrition 0.000 description 1
- 235000003392 Curcuma domestica Nutrition 0.000 description 1
- 244000008991 Curcuma longa Species 0.000 description 1
- 240000002943 Elettaria cardamomum Species 0.000 description 1
- FWCXELAAYFYCSR-UHFFFAOYSA-N Episamogenin Natural products CC1C(C2(CCC3C4(C)CC(O)C(O)CC4CCC3C2C2)C)C2OC11CCC(C)CO1 FWCXELAAYFYCSR-UHFFFAOYSA-N 0.000 description 1
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- DWCSNWXARWMZTG-UHFFFAOYSA-N Trigonegenin A Natural products CC1C(C2(CCC3C4(C)CCC(O)C=C4CCC3C2C2)C)C2OC11CCC(C)CO1 DWCSNWXARWMZTG-UHFFFAOYSA-N 0.000 description 1
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- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
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- 239000000470 constituent Substances 0.000 description 1
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- 235000021438 curry Nutrition 0.000 description 1
- 235000019503 curry powder Nutrition 0.000 description 1
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- 230000006866 deterioration Effects 0.000 description 1
- WQLVFSAGQJTQCK-VKROHFNGSA-N diosgenin Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CC[C@H](O)CC4=CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 WQLVFSAGQJTQCK-VKROHFNGSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Definitions
- the present invention relates to a supplementary food compositions for human health, and method of preparation thereof.
- composition comprising five main ingredients, said ingredients are: trigonella feonum-graecum, zingiber offcinale, allium sativum, cinnamomun zaylanicum, and nigella sativa. It is yet a further object of the present invention to provide a composition for boosting and enhancing immune system.
- the present invention provides a natural food supplement for boosting and enhancing the immune system.
- a food supplement having plant compositions for its ingredient.
- It is another object of the present invention to provide a method for manufacturing a herbal composition comprising the steps of: cleaning the raw materials (301) , drying said cleansed raw materials
- a method for manufacturing a herbal composition for enhancing and boosting immune system comprising trigonella feonum-graecum; zingiber officinale; allium sativum, cinnamomun zeylanicum and nigella sativa
- said method comprises the steps of: cleaning the raw materials (301), drying said cleansed raw materials (302) , subjecting said raw materials to a first grinding process (303) to obtain rough particles, subjecting said raw materials to a second grinding process (305) to obtain a superfine particles, subjecting said raw materials to a concentrator (310) to obtain a concentrated end-product; subjecting said materials to a second drying . process (311); subjecting said materials to a mixing process (306); and packaging said materials.
- FIG. 1 Illustrates the flow of process of making an embodiment of the present invention.
- FIG. 2 illustrates the overall flow of manufacturing the composition in accordance with a preferred embodiment of the present invention.
- composition of the present invention There are five plant ingredients or plant types involved in the making of the composition of the present invention. These ingredients are trigonella feonum-graecum , zingiber officinale, allium sativum, cinnamomum zaylanicum, and nigella sativa. The ingredients are easily found as they are typically used for cooking.
- Trigonella foenum-graecum is a plant in the family Fabacae. Trigonella foenum-graecum is used both as a herb (the leaves) ingredient and as a spice (the seed) . It is cultivated worldwide as a semi-arid crop. It is frequently used in curry. Trigonella foenum-graecum seeds are a rich source of the polysaccharide galactomannan . They are also a source of saponins such as diosgenin, yamogenin, gitogenin, tigogenin and neotigogens. Other bioactive constituents of trigonella foenum-graecum include mucilage, volatile oils, and alkaloids such as choline and trigonelline.
- Zingiber officinale is a tuber that is consumed whole as a delicacy, medicine, or spice.. It lends its name to its genus and family (Zingiberacae) . Other notable members of this plant " family are turmeric, cardamom, and galangal. Zingiber officinale cultivation began in Asia and has since spread to West Africa and Caribbean. It is sometimes called root zingiber officinale to distinguish it from other things that share the name zingiber officinale . Allium sativum is a species in the onion family Alliaceae . Its close relatives include the onion, shallot, leek, and chive. Allium sativum has been used throughout history for both culinary and medicinal purposes.
- a bulb of allium sativum the most commonly used part of the plant, is divided into numerous fleshy sections called cloves. Single clove allium sativum also exists - it originates in the Yunnan province of China. The cloves are used for cloning, consumption (raw or cooked), or medicinal purposes. The leaves, stems (scape) and flowers (bulbils) on the head (spathe) are also edible and are most often consumed while immature and still tender. The " papery, protective leaves of "skin” over various parts of the plant and the roots attached to the bulb only parts not considered palatable.
- Cinnamomum zeylanieum is a small evergreen tree belonging to the family Lauraceae, native to Sri Lanka, or the spice obtained from the tree's bark. It is often confused with other similar species and the similar spices derived from them, such as Cassia and Cinnamomum burmannii. Cinnamomum zeylanieum lowers the rate of cellular respiration in yeast. Cinnamomum zeylanieum bark is widely used as a spice. It is principally employed in cookery as a condiment and flavoring material. It is used in the preparation of chocolate, especially in Mexico, which is the main importer of true Cinnamomum zeylanieum.
- Cinnamomum zeylanieum can also be used in pickling. Cinnamomum zeylanieum bark is one of the few spices that can be consumed directly. Cinnamomum zeylanieum powder has long been an important spice in Persian cuisine, used in a variety of thick soups, drinks, and sweets. It is often mixed with rosewater or other spices to make a cinnamomum zeylanieum -based curry powder for stews or just sprinkled on sweet treats.
- Nigela sativa is an annual flowering plant, native to southwest Asia. It grows to 20-30cm (7.9 -12 in) tall, with finely divided, linear (but not thread-like) leaves. The flowers are delicate, and usually coloured pale blue and white, with 5-10 petals.
- the fruit is a large and inflated capsule composed of 3-7 united follicles, each containing numerous seeds. The seed is used as a spice.
- All the five ingredients namely trigonella feonum-graecum, zingiber offcinale, allium sativum, cinnamomun zaylanicum, and nigella sativa are cleaned first before being dried.
- the drying process is vital in ensuring the composition of the present invention lasting long.
- the ingredients are left under the sun for a certain period to dry.
- the ingredients are dried by heating them on the pan, or else heating them using microwave oven.
- the ingredients are grinded to powder.
- the grinding process can be done using grinding machine or manually. However, it is preferable to grind using the grinding machine in order to obtain the finest form of powder.
- the ingredients are grinded to powder so that the mixture of the ingredients can be packed into a form which is suitable for oral administration.
- a form which is suitable for oral administration may include, but not limiting to, pills, or tablets, or capsule, or packed in sachets to be served as syrup powder or other forms of food supplementary ingredients.
- each ingredient is present in certain range of percentage of total mass of the composition. In one preparation, each ingredient is present in certain range of percentage of total mass of the composition.
- the preferred amount of trigonella feonum- graecum ranges from 5 to 15% by weight, the zingiber officinale ranges from 3 to 10% by weight, the allium sativum ranges from 30 to 60% by weight, the cinnamomum zeylanicum ranges from 3 to 10%, and the nigella sativa ranges from 40 to 65% by weight of the total mass of the composition.
- FIG 2 shows the overall process flow of the preferred method of manufacturing the herbal composition of the present invention.
- the first step 301 is the cleansing of raw materials.
- the raw materials comprising of trigonella feonum-graecum, zingiber officinale, allium sativum, cinnamomom zaylanicum and nigella sativa, are cleansed.
- Such process may be informed with various conventional ways, for instance, but not limiting to, by means of a wash basin.
- the raw materials are then subjected to a drying process which may be conducted by means of an oven dryer or a freeze dryer as seen in step 302 and step 302a.
- the dried raw materials are subjected to a roughness grinder, which would result to reducing the dimension of the raw materials into rough particles.
- the materials which are in the form of rough particles may be subjected to a plurality of processes, whereby these processes are; packing them into sachets as final product in step 304, subjecting said rough particles of raw materials to a superfine grinding process, which is the second grinding process; or subjecting said particles to an extracting process.
- the fine particles obtained from this process are then subjected to a mixing process in step 306 prior to be packaged in tablet form by means of a tableting machine in step 307.
- the formed tablets are then provided as blister packages as shown in step 308.
- the rough particles are subjected to extracting process in step 309, thus obtaining the extracts of plants.
- the extracted resultant are then subjected to a concentrator in step 310 then a secondary drying process in step 311.
- the concentrator therefore is configured to produce a highly concentrated end-product based on the raw materials of the present invention.
- the secondary drying process may be performed by means of a vacuum belt dryer or a spray dryer. From the drying process, the dried materials are subjected to the mixing process in step 306 and then formed into capsules or tablets.
- composition may be provided in extracts form, based on the plant ingredients.
- the composition in the event that the concentrated product to a second mixing process of step 312, the composition may be subjected to several processes to obtain final product, whereby these processes are; production of soft gel in step 313 or bottling process as in step 314.
- composition may be prepared in various suitable forms for direct or oral administration for providing the boosting and enhancing immune system effects.
- compositions of the invention include those suitable for oral, rectal, optical, parenteral (for example, subcutaneous, intramuscular, intradermal and intravenous) and transdermal administration.
- parenteral for example, subcutaneous, intramuscular, intradermal and intravenous
- transdermal administration The most suitable route in any given case will depend on the nature and severity of the condition being treated and the state of the patient in need thereof.
- compositions suitable for oral administration may be presented in discrete units, such as capsules, sachets, lozenges, or tablets, each containing a pre-determined amount of the extract: as a powder or granules; as a solution or a suspension in an aqueous or nonaqueous liquid.
- the compositions of the invention are prepared by uniformly and intimately admixing the extract with a liquid or finely divided solid carrier, or both, and then, if necessary, shaping the resulting mixture.
- a tablet may be prepared by compressing or moulding a powder or granules containing the extract, optionally with one or more accessory ingredients.
- Compressed tablets may be prepared with the method disclosed herein or, optionally mixed with a binder, lubricant, inert diluents, and/or surface active/dispersing agent (s) .
- Moulded tablets may be made by moulding, in a suitable machine, the powdered compound moistened with an inert liquid binder.
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR112012022979A BR112012022979A2 (en) | 2010-03-12 | 2011-02-18 | a composition to stimulate and strengthen the immune system and its method of preparation |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MYPI2010001103A MY148964A (en) | 2010-03-12 | 2010-03-12 | A composition to boost and enhance immune system |
MYPI2010001103 | 2010-03-12 | ||
MYPI2011000733 | 2011-02-17 | ||
MYPI2011000733A MY160444A (en) | 2010-03-12 | 2011-02-17 | Method for preparing and manufacturing a composition to boost and enchange immune system |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011112070A2 true WO2011112070A2 (en) | 2011-09-15 |
WO2011112070A3 WO2011112070A3 (en) | 2012-03-29 |
Family
ID=44564042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/MY2011/000015 WO2011112070A2 (en) | 2010-03-12 | 2011-02-18 | A composition to boost and enhance immune system and method of preparing thereof |
Country Status (2)
Country | Link |
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BR (1) | BR112012022979A2 (en) |
WO (1) | WO2011112070A2 (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998025481A1 (en) * | 1996-12-10 | 1998-06-18 | Wakunaga Pharmaceutical Co., Ltd. | Fermented garlic composition |
WO2001003716A1 (en) * | 1999-07-09 | 2001-01-18 | Sun Farm Corporation | Method of treating malignancies and viral infections and improving immune function with a dietary supplement |
WO2002067986A2 (en) * | 2001-02-02 | 2002-09-06 | Schuer Joerg | Symbiotic regenerative agent |
KR100519720B1 (en) * | 2002-05-09 | 2005-10-10 | 한국원자력연구소 | A propolis-containing mixture reducing damages induced by reactive oxygen and radiation and enhancing immune activity, and its preparation |
KR20090126681A (en) * | 2008-06-05 | 2009-12-09 | 경희대학교 산학협력단 | A health supplement food for immune modulation produced with herbal mixture extracts of panax ginseng, acanthopanacis cortex and korean mountain ginseng adventitious roots |
-
2011
- 2011-02-18 BR BR112012022979A patent/BR112012022979A2/en not_active IP Right Cessation
- 2011-02-18 WO PCT/MY2011/000015 patent/WO2011112070A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998025481A1 (en) * | 1996-12-10 | 1998-06-18 | Wakunaga Pharmaceutical Co., Ltd. | Fermented garlic composition |
WO2001003716A1 (en) * | 1999-07-09 | 2001-01-18 | Sun Farm Corporation | Method of treating malignancies and viral infections and improving immune function with a dietary supplement |
WO2002067986A2 (en) * | 2001-02-02 | 2002-09-06 | Schuer Joerg | Symbiotic regenerative agent |
KR100519720B1 (en) * | 2002-05-09 | 2005-10-10 | 한국원자력연구소 | A propolis-containing mixture reducing damages induced by reactive oxygen and radiation and enhancing immune activity, and its preparation |
KR20090126681A (en) * | 2008-06-05 | 2009-12-09 | 경희대학교 산학협력단 | A health supplement food for immune modulation produced with herbal mixture extracts of panax ginseng, acanthopanacis cortex and korean mountain ginseng adventitious roots |
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Publication number | Publication date |
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BR112012022979A2 (en) | 2017-06-06 |
WO2011112070A3 (en) | 2012-03-29 |
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