WO2011083495A3 - Process for the preparation of dihydroxy protected derivatives and novel intermediate compounds - Google Patents
Process for the preparation of dihydroxy protected derivatives and novel intermediate compounds Download PDFInfo
- Publication number
- WO2011083495A3 WO2011083495A3 PCT/IN2011/000011 IN2011000011W WO2011083495A3 WO 2011083495 A3 WO2011083495 A3 WO 2011083495A3 IN 2011000011 W IN2011000011 W IN 2011000011W WO 2011083495 A3 WO2011083495 A3 WO 2011083495A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- protected derivatives
- intermediate compounds
- novel intermediate
- dihydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The present invention relates to an improved process for the preparation of dihydroxy protected derivatives, which are important intermediates in the preparation of HMG-CoA reductase inhibitors.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN41CH2010 | 2010-01-07 | ||
IN41/CHE/2010 | 2010-01-07 | ||
IN471/CHE/2010 | 2010-02-24 | ||
IN471CH2010 | 2010-02-24 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2011083495A2 WO2011083495A2 (en) | 2011-07-14 |
WO2011083495A8 WO2011083495A8 (en) | 2011-08-25 |
WO2011083495A3 true WO2011083495A3 (en) | 2011-10-13 |
Family
ID=44305898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2011/000011 WO2011083495A2 (en) | 2010-01-07 | 2011-01-07 | Process for the preparation of dihydroxy protected derivatives and novel intermediate compounds |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011083495A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011086584A2 (en) * | 2010-01-18 | 2011-07-21 | Msn Laboratories Limited | Improved process for the preparation of amide intermediates and their use thereof |
CN104513232A (en) * | 2015-01-08 | 2015-04-15 | 苏州莱克施德药业有限公司 | Preparation process for rosuvastatin ethyl ester |
CN109574938B (en) * | 2017-09-28 | 2022-04-22 | 安徽省庆云医药股份有限公司 | Method for synthesizing rosuvastatin sodium |
CN113956243A (en) * | 2020-12-31 | 2022-01-21 | 宣城美诺华药业有限公司 | Rosuvastatin intermediate and preparation method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000054207A1 (en) * | 1999-03-09 | 2000-09-14 | Schlumberger Technology Corporation | Seismic signal processing method and apparatus for generating a cube of variance values |
WO2007125547A2 (en) * | 2006-05-03 | 2007-11-08 | Manne Satyanarayana Reddy | Novel process for statins and its pharmaceutically acceptable salts thereof |
WO2010023678A1 (en) * | 2008-08-27 | 2010-03-04 | Biocon Limited | A process for preparation of rosuvastatin intermediate |
-
2011
- 2011-01-07 WO PCT/IN2011/000011 patent/WO2011083495A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000054207A1 (en) * | 1999-03-09 | 2000-09-14 | Schlumberger Technology Corporation | Seismic signal processing method and apparatus for generating a cube of variance values |
WO2007125547A2 (en) * | 2006-05-03 | 2007-11-08 | Manne Satyanarayana Reddy | Novel process for statins and its pharmaceutically acceptable salts thereof |
WO2010023678A1 (en) * | 2008-08-27 | 2010-03-04 | Biocon Limited | A process for preparation of rosuvastatin intermediate |
Also Published As
Publication number | Publication date |
---|---|
WO2011083495A8 (en) | 2011-08-25 |
WO2011083495A2 (en) | 2011-07-14 |
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