WO2011071360A3 - Síntesis de 8-aminoborodipirrometenos con fluorescencia azul - Google Patents
Síntesis de 8-aminoborodipirrometenos con fluorescencia azul Download PDFInfo
- Publication number
- WO2011071360A3 WO2011071360A3 PCT/MX2010/000151 MX2010000151W WO2011071360A3 WO 2011071360 A3 WO2011071360 A3 WO 2011071360A3 MX 2010000151 W MX2010000151 W MX 2010000151W WO 2011071360 A3 WO2011071360 A3 WO 2011071360A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- amino derivative
- compound
- dipyrromethenes
- synthesis
- boron
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000001412 amines Chemical class 0.000 abstract 3
- 238000004873 anchoring Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- JKANAVGODYYCQF-UHFFFAOYSA-N prop-2-yn-1-amine Chemical compound NCC#C JKANAVGODYYCQF-UHFFFAOYSA-N 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 125000004001 thioalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
Abstract
Nuestro grupo de investigación encontró que se puede sustituir al grupo tioalquilo que se encuentra en la posición 8 del cuerpo del borodipirrometno, con in aminoderivado. Se descubre que al tener anclado este aminoderivado cambia el comportamiento que normalmente tienen los borodipirrometenos, haciendo que este nuevo compuesto con el aminoderivado anclado en la posición 8, fluoresca de color azul, con lo que obtenemos compuestos con características de fluoresecnia de las cuales, hasta la fecha no se tiene registro de algún compuesto que fluoresca color azul, y otro asunto importante es la estrategia de síntesis, que resulta ser muy sencilla y con rendimientos muy altos, a parte que el estudio fotofísico realizado a la propargilamina revela que el compuesto tiene propiedades muy interesantes, y que le dan una potencial utilización en varias áreas de la ciencia, por decir la que resalta mas es su uso como láser. Asimismo, los derivados 6 y 7 se pueden utilizar para incorporar péptidos y proteínas y así obtener biomoléculas marcadas con fragmentos fluorescentes.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES10836252.6T ES2595212T3 (es) | 2009-12-10 | 2010-12-10 | Síntesis de 8-aminoboro-dipirrometenos con fluorescencia azul |
US13/512,734 US8710220B2 (en) | 2009-12-10 | 2010-12-10 | Synthesis of 8-amino boron dipyrromethenes having blue fluorescence |
EP10836252.6A EP2511277B1 (en) | 2009-12-10 | 2010-12-10 | Synthesis of 8-aminoboron-dipyrromethenes having blue fluorescence |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXMX/A/2009/013486 | 2009-12-10 | ||
MX2009013486A MX2009013486A (es) | 2009-12-10 | 2009-12-10 | Sintesis de 8-aminoborodipirrometenos con fluorescencia azul. |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011071360A2 WO2011071360A2 (es) | 2011-06-16 |
WO2011071360A3 true WO2011071360A3 (es) | 2011-09-22 |
Family
ID=44146086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/MX2010/000151 WO2011071360A2 (es) | 2009-12-10 | 2010-12-10 | Síntesis de 8-aminoborodipirrometenos con fluorescencia azul |
Country Status (5)
Country | Link |
---|---|
US (1) | US8710220B2 (es) |
EP (1) | EP2511277B1 (es) |
ES (1) | ES2595212T3 (es) |
MX (1) | MX2009013486A (es) |
WO (1) | WO2011071360A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102148067B1 (ko) * | 2016-09-02 | 2020-08-26 | 주식회사 엘지화학 | 화합물 및 이를 포함하는 색변환필름 |
KR102157933B1 (ko) * | 2017-12-27 | 2020-09-18 | 주식회사 엘지화학 | 함질소 고리 화합물 및 이를 포함하는 색변환 필름 |
CN112940021A (zh) * | 2019-12-10 | 2021-06-11 | 中国科学院大连化学物理研究所 | 一类高亮度、多色免洗脂滴荧光探针 |
CN112940020A (zh) * | 2019-12-10 | 2021-06-11 | 中国科学院大连化学物理研究所 | 一类405nm激发的高亮度免洗脂滴荧光探针及其合成方法与应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916711A (en) * | 1988-09-29 | 1990-04-10 | Boyer Joseph H | Lasing compositions and methods for using the same |
WO1994019355A1 (en) * | 1993-02-19 | 1994-09-01 | Bo-Dekk Ventures, Ltd. | Chemical compounds useful in photodynamic therapy and production of laser light |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3857793A (en) | 1973-05-01 | 1974-12-31 | Gte Laboratories Inc | Fluorescent organic compound laser |
JP4452619B2 (ja) | 2002-08-23 | 2010-04-21 | 独立行政法人理化学研究所 | 色素蛋白質及び蛍光蛋白質 |
AU2004248055B2 (en) | 2003-06-16 | 2009-05-14 | Medical & Biological Laboratories Co., Ltd. | Fluorescent protein |
WO2005118606A1 (ja) | 2004-06-04 | 2005-12-15 | National Institute Of Advanced Industrial Science And Technology | フッ素置換イリジウム錯体およびこれを用いた発光材料 |
-
2009
- 2009-12-10 MX MX2009013486A patent/MX2009013486A/es active IP Right Grant
-
2010
- 2010-12-10 US US13/512,734 patent/US8710220B2/en active Active
- 2010-12-10 EP EP10836252.6A patent/EP2511277B1/en active Active
- 2010-12-10 WO PCT/MX2010/000151 patent/WO2011071360A2/es active Application Filing
- 2010-12-10 ES ES10836252.6T patent/ES2595212T3/es active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916711A (en) * | 1988-09-29 | 1990-04-10 | Boyer Joseph H | Lasing compositions and methods for using the same |
WO1994019355A1 (en) * | 1993-02-19 | 1994-09-01 | Bo-Dekk Ventures, Ltd. | Chemical compounds useful in photodynamic therapy and production of laser light |
Non-Patent Citations (3)
Title |
---|
ACEBAL, P. ET AL.: "Theorical study of second-order non-linear optical properties of pyrromethene dyes for photonic application", JOURNAL OF PHYSICS B: ATOMIC, MOLECULAR AND OPTICAL PHYSICS, vol. 36, 2003, pages 2445 - 2454, XP008157332 * |
GOMEZ-DURDN, C.F. ET AL.: "8-PropargylaminoBODIPY: unprecedented blue-emitting pyrromethene dye. Synthesis, photophysics and laser properties", CHEMICAL COMMUNICATIONS, vol. 46, 2010, pages 5103 - 5105, XP008157347 * |
See also references of EP2511277A2 * |
Also Published As
Publication number | Publication date |
---|---|
US8710220B2 (en) | 2014-04-29 |
US20120253050A1 (en) | 2012-10-04 |
WO2011071360A2 (es) | 2011-06-16 |
EP2511277A4 (en) | 2013-04-17 |
MX2009013486A (es) | 2011-06-14 |
ES2595212T3 (es) | 2016-12-28 |
EP2511277A2 (en) | 2012-10-17 |
EP2511277B1 (en) | 2016-07-13 |
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