WO2011069936A1 - Drive assembly for a drug delivery device and drug delivery device - Google Patents
Drive assembly for a drug delivery device and drug delivery device Download PDFInfo
- Publication number
- WO2011069936A1 WO2011069936A1 PCT/EP2010/068916 EP2010068916W WO2011069936A1 WO 2011069936 A1 WO2011069936 A1 WO 2011069936A1 EP 2010068916 W EP2010068916 W EP 2010068916W WO 2011069936 A1 WO2011069936 A1 WO 2011069936A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- piston rod
- drive member
- housing
- drive assembly
- relative
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/482—Varying injection pressure, e.g. by varying speed of injection
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012542483A JP5816191B2 (ja) | 2009-12-07 | 2010-12-06 | 薬物送達デバイス用の駆動アセンブリ及び薬物送達デバイス |
| CN201080060957.5A CN102695532B (zh) | 2009-12-07 | 2010-12-06 | 用于药物传输装置的驱动组件和药物传输装置 |
| US13/509,602 US9022993B2 (en) | 2009-12-07 | 2010-12-06 | Drive assembly for a drug delivery device and drug delivery device |
| BR112012013767A BR112012013767A2 (pt) | 2009-12-07 | 2010-12-06 | montagem de acionamento para um dispositivo de entrega de fármaco e dispositivo de entrega de fármaco |
| EP10800903.6A EP2509663B1 (en) | 2009-12-07 | 2010-12-06 | Drive assembly for a drug delivery device and drug delivery device |
| AU2010330033A AU2010330033B2 (en) | 2009-12-07 | 2010-12-06 | Drive assembly for a drug delivery device and drug delivery device |
| CA2779389A CA2779389A1 (en) | 2009-12-07 | 2010-12-06 | Drive assembly for a drug delivery device and drug delivery device |
| DK10800903.6T DK2509663T3 (en) | 2009-12-07 | 2010-12-06 | DRIVING FOR A DRUG SUPPLY AND PHARMACEUTICAL DRIVING DEVICE |
| IL220169A IL220169A (en) | 2009-12-07 | 2012-06-04 | Thrust Array for Drug Release Device and Drug Release Device |
| HK13104516.2A HK1176898A1 (en) | 2009-12-07 | 2013-04-15 | Drive assembly for a drug delivery device and drug delivery device |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09178215.1 | 2009-12-07 | ||
| EP09178215 | 2009-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2011069936A1 true WO2011069936A1 (en) | 2011-06-16 |
Family
ID=42455318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2010/068916 WO2011069936A1 (en) | 2009-12-07 | 2010-12-06 | Drive assembly for a drug delivery device and drug delivery device |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9022993B2 (ja) |
| EP (1) | EP2509663B1 (ja) |
| JP (1) | JP5816191B2 (ja) |
| CN (1) | CN102695532B (ja) |
| AU (1) | AU2010330033B2 (ja) |
| BR (1) | BR112012013767A2 (ja) |
| CA (1) | CA2779389A1 (ja) |
| DK (1) | DK2509663T3 (ja) |
| HK (1) | HK1176898A1 (ja) |
| IL (1) | IL220169A (ja) |
| WO (1) | WO2011069936A1 (ja) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945063B2 (en) | 2009-03-20 | 2015-02-03 | Antares Pharma, Inc. | Hazardous agent injection system |
| US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
| US9180259B2 (en) | 2005-01-24 | 2015-11-10 | Antares Pharma, Inc. | Prefilled syringe jet injector |
| US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
| US9333309B2 (en) | 2002-02-11 | 2016-05-10 | Antares Pharma, Inc. | Intradermal injector |
| US9364610B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US9393367B2 (en) | 2013-03-12 | 2016-07-19 | Antares Pharma, Inc. | Prefilled syringes and kits thereof |
| US9446195B2 (en) | 2011-07-15 | 2016-09-20 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US9486583B2 (en) | 2012-03-06 | 2016-11-08 | Antares Pharma, Inc. | Prefilled syringe with breakaway force feature |
| US9561333B2 (en) | 2008-08-05 | 2017-02-07 | Antares Pharma, Inc. | Multiple dosage injector |
| US9707354B2 (en) | 2013-03-11 | 2017-07-18 | Antares Pharma, Inc. | Multiple dosage injector with rack and pinion dosage system |
| US9744302B2 (en) | 2013-02-11 | 2017-08-29 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
| US9808582B2 (en) | 2006-05-03 | 2017-11-07 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| US9867949B2 (en) | 2008-03-10 | 2018-01-16 | Antares Pharma, Inc. | Injector safety device |
| US9950125B2 (en) | 2012-04-06 | 2018-04-24 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120283652A1 (en) * | 2009-09-30 | 2012-11-08 | Sanofi-Aventis Deutschland Gmbh | Assembly and Piston Rod for a Drug Delivery Device |
| EP2399635A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| DK2627382T3 (en) * | 2010-10-11 | 2016-07-25 | Shl Group Ab | Drug delivery devices |
| EP2468333A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| USRE48593E1 (en) | 2010-12-21 | 2021-06-15 | Sanofi-Aventis Deutschland Gmbh | Auto-injector |
| AU2012269060B2 (en) * | 2011-06-17 | 2016-07-14 | Sanofi-Aventis Deutschland Gmbh | Cartridge holder assembly for drug delivery devices |
| US8834449B2 (en) | 2012-01-23 | 2014-09-16 | Ikomed Technologies, Inc. | Mixing syringe |
| US9751056B2 (en) | 2012-01-23 | 2017-09-05 | Merit Medical Systems, Inc. | Mixing syringe |
| EP2823841A1 (en) | 2013-07-09 | 2015-01-14 | Sanofi-Aventis Deutschland GmbH | Autoinjector |
| EP2923714A1 (en) | 2014-03-28 | 2015-09-30 | Sanofi-Aventis Deutschland GmbH | Autoinjector triggered by skin contact |
| US11577028B2 (en) * | 2021-01-20 | 2023-02-14 | Becton, Dickinson And Company | Syringe with a bidirectional plunger advancing mechanism for a micro-dosing syringe pump |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4475905A (en) * | 1982-09-30 | 1984-10-09 | Himmelstrup Anders B | Injection device |
| WO2000062847A1 (en) * | 1999-04-16 | 2000-10-26 | Pharmacia Ab | Injector device and method for its operation |
| US20060229570A1 (en) * | 2002-09-11 | 2006-10-12 | Becton, Dickinson And Company | Injector device with force lock-out and injection rate limiting mechanisms |
| EP1875935A2 (de) | 1998-05-15 | 2008-01-09 | Tecpharma Licensing AG | Autoinjektionsgerät |
| WO2009136209A1 (en) * | 2008-05-09 | 2009-11-12 | Owen Mumford Limited | Electrically actuated injector |
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| US5256152A (en) * | 1991-10-29 | 1993-10-26 | Marks Lloyd A | Safety needle and method of using same |
| GB9300567D0 (en) * | 1993-01-12 | 1993-03-03 | Owen Mumford Ltd | Improvements relating to devices for generating intermittent motion |
| CN101903059B (zh) * | 2007-12-20 | 2013-06-19 | 诺沃-诺迪斯克有限公司 | 用于输送固定剂量液态药物的注射装置 |
-
2010
- 2010-12-06 CA CA2779389A patent/CA2779389A1/en not_active Abandoned
- 2010-12-06 AU AU2010330033A patent/AU2010330033B2/en not_active Ceased
- 2010-12-06 US US13/509,602 patent/US9022993B2/en active Active
- 2010-12-06 WO PCT/EP2010/068916 patent/WO2011069936A1/en active Application Filing
- 2010-12-06 CN CN201080060957.5A patent/CN102695532B/zh not_active Expired - Fee Related
- 2010-12-06 JP JP2012542483A patent/JP5816191B2/ja not_active Expired - Fee Related
- 2010-12-06 DK DK10800903.6T patent/DK2509663T3/en active
- 2010-12-06 EP EP10800903.6A patent/EP2509663B1/en active Active
- 2010-12-06 BR BR112012013767A patent/BR112012013767A2/pt not_active IP Right Cessation
-
2012
- 2012-06-04 IL IL220169A patent/IL220169A/en not_active IP Right Cessation
-
2013
- 2013-04-15 HK HK13104516.2A patent/HK1176898A1/xx not_active IP Right Cessation
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| US4475905A (en) * | 1982-09-30 | 1984-10-09 | Himmelstrup Anders B | Injection device |
| EP1875935A2 (de) | 1998-05-15 | 2008-01-09 | Tecpharma Licensing AG | Autoinjektionsgerät |
| WO2000062847A1 (en) * | 1999-04-16 | 2000-10-26 | Pharmacia Ab | Injector device and method for its operation |
| US20060229570A1 (en) * | 2002-09-11 | 2006-10-12 | Becton, Dickinson And Company | Injector device with force lock-out and injection rate limiting mechanisms |
| WO2009136209A1 (en) * | 2008-05-09 | 2009-11-12 | Owen Mumford Limited | Electrically actuated injector |
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| Title |
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| "Remington's Pharmaceutical Sciences", 1985, MARK PUBLISHING COMPANY |
Cited By (45)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US9333309B2 (en) | 2002-02-11 | 2016-05-10 | Antares Pharma, Inc. | Intradermal injector |
| US9737670B2 (en) | 2002-02-11 | 2017-08-22 | Antares Pharma, Inc. | Intradermal injector |
| US10478560B2 (en) | 2005-01-24 | 2019-11-19 | Antares Pharma, Inc. | Prefilled syringe injector |
| US9180259B2 (en) | 2005-01-24 | 2015-11-10 | Antares Pharma, Inc. | Prefilled syringe jet injector |
| US11446441B2 (en) | 2005-01-24 | 2022-09-20 | Antares Pharma, Inc. | Prefilled syringe injector |
| US9629959B2 (en) | 2005-01-24 | 2017-04-25 | Antares Pharma, Inc. | Prefilled syringe jet injector |
| US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
| US10688250B2 (en) | 2006-05-03 | 2020-06-23 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| US11471600B2 (en) | 2006-05-03 | 2022-10-18 | Antares Pharma, Inc. | Injector with adjustable dosing |
| US10543316B2 (en) | 2006-05-03 | 2020-01-28 | Antares Pharma, Inc. | Injector with adjustable dosing |
| US9808582B2 (en) | 2006-05-03 | 2017-11-07 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| US11547808B2 (en) | 2006-05-03 | 2023-01-10 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| US9867949B2 (en) | 2008-03-10 | 2018-01-16 | Antares Pharma, Inc. | Injector safety device |
| US10709844B2 (en) | 2008-03-10 | 2020-07-14 | Antares Pharma, Inc. | Injector safety device |
| US11684723B2 (en) | 2008-03-10 | 2023-06-27 | Antares Pharma, Inc. | Injector safety device |
| US10300212B2 (en) | 2008-08-05 | 2019-05-28 | Antares Pharma, Inc. | Multiple dosage injector |
| US9561333B2 (en) | 2008-08-05 | 2017-02-07 | Antares Pharma, Inc. | Multiple dosage injector |
| US11058824B2 (en) | 2008-08-05 | 2021-07-13 | Antares Pharma, Inc. | Multiple dosage injector |
| US10555954B2 (en) | 2009-03-20 | 2020-02-11 | Antares Pharma, Inc. | Hazardous agent injection system |
| US9750881B2 (en) | 2009-03-20 | 2017-09-05 | Antares Pharma, Inc. | Hazardous agent injection system |
| US11497753B2 (en) | 2009-03-20 | 2022-11-15 | Antares Pharma, Inc. | Hazardous agent injection system |
| US8945063B2 (en) | 2009-03-20 | 2015-02-03 | Antares Pharma, Inc. | Hazardous agent injection system |
| US10568809B2 (en) | 2011-07-15 | 2020-02-25 | Ferring B.V. | Liquid-transfer adapter beveled spike |
| US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
| US9446195B2 (en) | 2011-07-15 | 2016-09-20 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US10279131B2 (en) | 2011-07-15 | 2019-05-07 | Antares Pharma, Inc. | Injection device with cammed RAM assembly |
| US11602597B2 (en) | 2012-03-06 | 2023-03-14 | Antares Pharma, Inc. | Prefilled syringe with breakaway force feature |
| US9486583B2 (en) | 2012-03-06 | 2016-11-08 | Antares Pharma, Inc. | Prefilled syringe with breakaway force feature |
| US10478559B2 (en) | 2012-03-06 | 2019-11-19 | Antares Pharma, Inc. | Prefilled syringe with breakaway force feature |
| US11771646B2 (en) | 2012-04-06 | 2023-10-03 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
| US9950125B2 (en) | 2012-04-06 | 2018-04-24 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
| US10821072B2 (en) | 2012-04-06 | 2020-11-03 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
| US9364610B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US10905827B2 (en) | 2012-05-07 | 2021-02-02 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US11446440B2 (en) | 2012-05-07 | 2022-09-20 | Antares Pharma, Inc. | Needle assisted injection device having reduced trigger force |
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| US10881798B2 (en) | 2013-02-11 | 2021-01-05 | Antares Pharma, Inc. | Needle assisted injection device having reduced trigger force |
| US9744302B2 (en) | 2013-02-11 | 2017-08-29 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
| US11813435B2 (en) | 2013-02-11 | 2023-11-14 | Antares Pharma, Inc. | Needle assisted injection device having reduced trigger force |
| US10610649B2 (en) | 2013-03-11 | 2020-04-07 | Antares Pharma, Inc. | Multiple dosage injector with rack and pinion dosage system |
| US9707354B2 (en) | 2013-03-11 | 2017-07-18 | Antares Pharma, Inc. | Multiple dosage injector with rack and pinion dosage system |
| US11628260B2 (en) | 2013-03-11 | 2023-04-18 | Antares Pharma, Inc. | Multiple dosage injector with rack and pinion dosage system |
| US10675400B2 (en) | 2013-03-12 | 2020-06-09 | Antares Pharma, Inc. | Prefilled syringes and kits thereof |
| US9393367B2 (en) | 2013-03-12 | 2016-07-19 | Antares Pharma, Inc. | Prefilled syringes and kits thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| IL220169A (en) | 2014-06-30 |
| HK1176898A1 (en) | 2013-08-09 |
| AU2010330033B2 (en) | 2014-10-23 |
| CN102695532B (zh) | 2015-02-18 |
| DK2509663T3 (en) | 2015-04-27 |
| CA2779389A1 (en) | 2011-06-16 |
| JP2013512744A (ja) | 2013-04-18 |
| IL220169A0 (en) | 2012-07-31 |
| US20130018327A1 (en) | 2013-01-17 |
| EP2509663B1 (en) | 2015-01-21 |
| AU2010330033A1 (en) | 2012-06-21 |
| CN102695532A (zh) | 2012-09-26 |
| EP2509663A1 (en) | 2012-10-17 |
| US9022993B2 (en) | 2015-05-05 |
| BR112012013767A2 (pt) | 2016-04-26 |
| JP5816191B2 (ja) | 2015-11-18 |
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