WO2011067758A3 - Fragments immunogènes et multimères pour protéines de streptococcus pneumoniae - Google Patents

Fragments immunogènes et multimères pour protéines de streptococcus pneumoniae Download PDF

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Publication number
WO2011067758A3
WO2011067758A3 PCT/IL2010/001009 IL2010001009W WO2011067758A3 WO 2011067758 A3 WO2011067758 A3 WO 2011067758A3 IL 2010001009 W IL2010001009 W IL 2010001009W WO 2011067758 A3 WO2011067758 A3 WO 2011067758A3
Authority
WO
WIPO (PCT)
Prior art keywords
multimers
streptococcus pneumoniae
immunogenic fragments
pneumoniae proteins
pneumoniae
Prior art date
Application number
PCT/IL2010/001009
Other languages
English (en)
Other versions
WO2011067758A2 (fr
Inventor
Yaffa Mizrachi-Nebenzahl
Michael Tal
Ron Dagan
Maxim Portnoi
Original Assignee
Protea Vaccine Technologies Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protea Vaccine Technologies Ltd. filed Critical Protea Vaccine Technologies Ltd.
Publication of WO2011067758A2 publication Critical patent/WO2011067758A2/fr
Publication of WO2011067758A3 publication Critical patent/WO2011067758A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6043—Heat shock proteins

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des fragments immunogènes, y compris des variantes et des analogues dérivés de protéines de Streptococcus pneumoniae (S. pneumoniae), des multimères de polypeptides et des protéines de fusion comprenant de tels polypeptides, et des vaccins comprenant de telles entités immunogènes. L'invention concerne notamment l'utilisation de tels vaccins pour provoquer une immunité protectrice contre S. pneumoniae.
PCT/IL2010/001009 2009-12-02 2010-12-01 Fragments immunogènes et multimères pour protéines de streptococcus pneumoniae WO2011067758A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26577209P 2009-12-02 2009-12-02
US61/265,772 2009-12-02

Publications (2)

Publication Number Publication Date
WO2011067758A2 WO2011067758A2 (fr) 2011-06-09
WO2011067758A3 true WO2011067758A3 (fr) 2011-10-13

Family

ID=43983528

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2010/001009 WO2011067758A2 (fr) 2009-12-02 2010-12-01 Fragments immunogènes et multimères pour protéines de streptococcus pneumoniae

Country Status (1)

Country Link
WO (1) WO2011067758A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201403702SA (en) 2009-06-29 2014-09-26 Genocea Biosciences Inc Vaccines and compositions against streptococcus pneumoniae
MY163871A (en) 2011-01-20 2017-10-31 Genocea Biosciences Inc Vaccines and compositions against streptococcus pneumoniae
WO2015189422A1 (fr) 2014-06-12 2015-12-17 Universidade Do Porto - Reitoria Vaccin pour hôtes immunodéprimés
EP2955194A1 (fr) * 2014-06-12 2015-12-16 Universidade do Porto - Reitoria Vaccin néonatal
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

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WO2002077021A2 (fr) * 2001-03-27 2002-10-03 Chiron Srl. Proteines et acides nucleiques de streptococcus pneumoniae
US20050187718A1 (en) * 2001-09-21 2005-08-25 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from Streptococcus pneumoniae

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077021A2 (fr) * 2001-03-27 2002-10-03 Chiron Srl. Proteines et acides nucleiques de streptococcus pneumoniae
US20050187718A1 (en) * 2001-09-21 2005-08-25 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from Streptococcus pneumoniae

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* Cited by examiner, † Cited by third party
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Publication number Publication date
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