WO2011066304A2 - Polypeptides génétiquement modifiés de l'anhydrase carbonique de classe bêta et utilisations de ceux-ci - Google Patents

Polypeptides génétiquement modifiés de l'anhydrase carbonique de classe bêta et utilisations de ceux-ci Download PDF

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Publication number
WO2011066304A2
WO2011066304A2 PCT/US2010/057843 US2010057843W WO2011066304A2 WO 2011066304 A2 WO2011066304 A2 WO 2011066304A2 US 2010057843 W US2010057843 W US 2010057843W WO 2011066304 A2 WO2011066304 A2 WO 2011066304A2
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WO
WIPO (PCT)
Prior art keywords
residue
position corresponding
carbonic anhydrase
polar
polypeptide
Prior art date
Application number
PCT/US2010/057843
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English (en)
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WO2011066304A3 (fr
Inventor
Louis Clark
Sabrina Zimmerman
Original Assignee
Codexis, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis, Inc. filed Critical Codexis, Inc.
Publication of WO2011066304A2 publication Critical patent/WO2011066304A2/fr
Publication of WO2011066304A3 publication Critical patent/WO2011066304A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P3/00—Preparation of elements or inorganic compounds except carbon dioxide

Abstract

La présente invention concerne des enzymes d'anhydrase carbonique de classe β génétiquement modifiées possédant des propriétés améliorées par comparaison à une anhydrase carbonique de classe β de type sauvage d'origine naturelle et les utilisations de celles-ci pour la séquestration du dioxyde de carbone ainsi que pour la libération de dioxyde de carbone à partir d'une composition comprenant du bicarbonate. L'invention concerne également des polynucléotides codant pour les enzymes anhydrase carbonique génétiquement modifiées et des cellules hôtes capables d'exprimer les enzymes anhydrase carbonique génétiquement modifiées.
PCT/US2010/057843 2009-11-25 2010-11-23 Polypeptides génétiquement modifiés de l'anhydrase carbonique de classe bêta et utilisations de ceux-ci WO2011066304A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26460009P 2009-11-25 2009-11-25
US61/264,600 2009-11-25

Publications (2)

Publication Number Publication Date
WO2011066304A2 true WO2011066304A2 (fr) 2011-06-03
WO2011066304A3 WO2011066304A3 (fr) 2012-01-12

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PCT/US2010/057843 WO2011066304A2 (fr) 2009-11-25 2010-11-23 Polypeptides génétiquement modifiés de l'anhydrase carbonique de classe bêta et utilisations de ceux-ci

Country Status (1)

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WO (1) WO2011066304A2 (fr)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8354262B2 (en) 2010-06-30 2013-01-15 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
US8354261B2 (en) 2010-06-30 2013-01-15 Codexis, Inc. Highly stable β-class carbonic anhydrases useful in carbon capture systems
WO2013028512A1 (fr) * 2011-08-19 2013-02-28 Novozymes, Inc. Microorganismes recombinants pour production d'acides dicarboxyliques en c4
US8420364B2 (en) 2010-06-30 2013-04-16 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
US8497103B2 (en) 2010-06-21 2013-07-30 Novozymes, Inc. Methods for C4-dicarboxylic acid production in filamentous fungi
US8518676B2 (en) 2010-06-21 2013-08-27 Novozymes, Inc. Polypeptides having C4 dicarboxylic acid transporter activity and polynucleotides encoding same
US8617859B2 (en) 2010-06-04 2013-12-31 Novozymes, Inc. C4 dicarboxylic acid production in filamentous fungi
US8722387B2 (en) 2011-02-28 2014-05-13 Novozymes, Inc. Microorganisms for C4-dicarboxylic acid production
US8741611B2 (en) 2009-09-01 2014-06-03 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
WO2014090327A1 (fr) * 2012-12-14 2014-06-19 Statoil Petoleum As Nouveaux enzymes pour une absorption gazeuse améliorée
EP3344764A4 (fr) * 2015-09-03 2019-04-10 CO2 Solutions Inc. Variants d'anhydrase carbonique dethermovibrio ammonificans
WO2020010427A1 (fr) * 2018-07-12 2020-01-16 Garnica Leonardo Procédé respiratoire inverse pour l'absorption de dioxyde de carbone

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060257990A1 (en) * 2005-04-21 2006-11-16 Co2 Solution Carbonic anhydrase having increased stability under high temperature conditions
WO2008095057A2 (fr) * 2007-01-31 2008-08-07 Novozymes A/S Anhydrases carboniques stables à la chaleur et leur utilisation
US20100209997A1 (en) * 2009-01-09 2010-08-19 Codexis, Inc. Carbonic anhydrase polypeptides and uses thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060257990A1 (en) * 2005-04-21 2006-11-16 Co2 Solution Carbonic anhydrase having increased stability under high temperature conditions
WO2008095057A2 (fr) * 2007-01-31 2008-08-07 Novozymes A/S Anhydrases carboniques stables à la chaleur et leur utilisation
US20100209997A1 (en) * 2009-01-09 2010-08-19 Codexis, Inc. Carbonic anhydrase polypeptides and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
STROP, P. ET AL.: 'Crystal structure of the ''cab''-type beta class carbonic anhydrase from the archaeon methanobacterium thermoautotrophicum' JOURNAL OF BIOLOGICAL CHEMISTRY vol. 276, no. 13, 28 November 2000, pages 10299 - 10305 *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8999685B2 (en) 2009-09-01 2015-04-07 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
US8741611B2 (en) 2009-09-01 2014-06-03 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
US8617859B2 (en) 2010-06-04 2013-12-31 Novozymes, Inc. C4 dicarboxylic acid production in filamentous fungi
US8497103B2 (en) 2010-06-21 2013-07-30 Novozymes, Inc. Methods for C4-dicarboxylic acid production in filamentous fungi
US8518676B2 (en) 2010-06-21 2013-08-27 Novozymes, Inc. Polypeptides having C4 dicarboxylic acid transporter activity and polynucleotides encoding same
US9303275B2 (en) 2010-06-21 2016-04-05 Novozymes, Inc. Polypeptides having C4 dicarboxylic acid transporter activity and polynucleotides encoding same
US8354261B2 (en) 2010-06-30 2013-01-15 Codexis, Inc. Highly stable β-class carbonic anhydrases useful in carbon capture systems
US8569031B2 (en) 2010-06-30 2013-10-29 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
US8420364B2 (en) 2010-06-30 2013-04-16 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
US8354262B2 (en) 2010-06-30 2013-01-15 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
US8512989B2 (en) 2010-06-30 2013-08-20 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
US8722387B2 (en) 2011-02-28 2014-05-13 Novozymes, Inc. Microorganisms for C4-dicarboxylic acid production
US9447440B2 (en) 2011-02-28 2016-09-20 Novozymes, Inc. Microorganisms for C4-dicarboxylic acid production
US8663956B2 (en) 2011-08-19 2014-03-04 Novozymes, Inc. Recombinant microorganisms for production C4-dicarboxylic acids
WO2013028512A1 (fr) * 2011-08-19 2013-02-28 Novozymes, Inc. Microorganismes recombinants pour production d'acides dicarboxyliques en c4
WO2014090327A1 (fr) * 2012-12-14 2014-06-19 Statoil Petoleum As Nouveaux enzymes pour une absorption gazeuse améliorée
EP3344764A4 (fr) * 2015-09-03 2019-04-10 CO2 Solutions Inc. Variants d'anhydrase carbonique dethermovibrio ammonificans
WO2020010427A1 (fr) * 2018-07-12 2020-01-16 Garnica Leonardo Procédé respiratoire inverse pour l'absorption de dioxyde de carbone

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Publication number Publication date
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