WO2011065729A3 - Biosensor - Google Patents

Biosensor Download PDF

Info

Publication number
WO2011065729A3
WO2011065729A3 PCT/KR2010/008305 KR2010008305W WO2011065729A3 WO 2011065729 A3 WO2011065729 A3 WO 2011065729A3 KR 2010008305 W KR2010008305 W KR 2010008305W WO 2011065729 A3 WO2011065729 A3 WO 2011065729A3
Authority
WO
WIPO (PCT)
Prior art keywords
channel
main body
biosensor
minimum width
introducing
Prior art date
Application number
PCT/KR2010/008305
Other languages
French (fr)
Korean (ko)
Other versions
WO2011065729A2 (en
Inventor
이현정
박지원
Original Assignee
주식회사 테크넬
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 테크넬 filed Critical 주식회사 테크넬
Publication of WO2011065729A2 publication Critical patent/WO2011065729A2/en
Publication of WO2011065729A3 publication Critical patent/WO2011065729A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The present invention relates to a biosensor, and more specifically relates to a biosensor in which the production reproducibility is enhanced by limiting the size, in the width direction, of a micro-channel for separating blood cells. In order to achieve the above aim, the present invention provides a biosensor which incorporates a main body and an upper plate joined to the upper edge of the main body, and which comprises: an introducing means for introducing blood formed on the upper surface of the main body; a channel which is formed on the upper surface of the main body and of which one side connects through to the introducing means; and a discharge means which is formed on the upper surface of the main body, connects through to the other side of the channel, and discharges air inside the channel to the outside for the purpose of blood movement; wherein the channel has a minimum width in one section, the minimum width is no less than 0.5 μm and no more than 1 μm, and the height of the channel is 10 times the minimum width.
PCT/KR2010/008305 2009-11-25 2010-11-23 Biosensor WO2011065729A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090114851A KR101004989B1 (en) 2009-11-25 2009-11-25 Bio-sensor
KR10-2009-0114851 2009-11-25

Publications (2)

Publication Number Publication Date
WO2011065729A2 WO2011065729A2 (en) 2011-06-03
WO2011065729A3 true WO2011065729A3 (en) 2011-10-27

Family

ID=43513508

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/008305 WO2011065729A2 (en) 2009-11-25 2010-11-23 Biosensor

Country Status (2)

Country Link
KR (1) KR101004989B1 (en)
WO (1) WO2011065729A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101429253B1 (en) * 2014-05-22 2014-08-12 (주) 굿모닝 바이오 Platelet activation device with multi-channel blood passage
KR101706750B1 (en) * 2015-08-19 2017-02-14 전남대학교산학협력단 Multichannel cell culture dish
KR101879500B1 (en) * 2016-08-01 2018-07-19 한국기계연구원 Micro-fluidic device with recovery function
CN114302808B (en) * 2019-06-28 2024-05-03 舒万诺知识产权公司 Article with conformal layer and method of making the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006119127A (en) * 2004-09-27 2006-05-11 Citizen Watch Co Ltd Biosensor
JP2006308561A (en) * 2005-03-29 2006-11-09 Citizen Watch Co Ltd Biosensor
KR100735898B1 (en) * 2006-08-25 2007-07-04 한국기계연구원 The portable micro blood separator
KR20070099233A (en) * 2006-04-04 2007-10-09 주식회사 올메디쿠스 Biosensor chip provided with blood separation means

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006119127A (en) * 2004-09-27 2006-05-11 Citizen Watch Co Ltd Biosensor
JP2006308561A (en) * 2005-03-29 2006-11-09 Citizen Watch Co Ltd Biosensor
KR20070099233A (en) * 2006-04-04 2007-10-09 주식회사 올메디쿠스 Biosensor chip provided with blood separation means
KR100735898B1 (en) * 2006-08-25 2007-07-04 한국기계연구원 The portable micro blood separator

Also Published As

Publication number Publication date
WO2011065729A2 (en) 2011-06-03
KR101004989B1 (en) 2010-12-29

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