WO2011061561A3 - Procédé destiné à obtenir des matrices moléculaires régénératrices et matrices moléculaires régénératrices ainsi obtenues - Google Patents

Procédé destiné à obtenir des matrices moléculaires régénératrices et matrices moléculaires régénératrices ainsi obtenues Download PDF

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Publication number
WO2011061561A3
WO2011061561A3 PCT/IB2009/055180 IB2009055180W WO2011061561A3 WO 2011061561 A3 WO2011061561 A3 WO 2011061561A3 IB 2009055180 W IB2009055180 W IB 2009055180W WO 2011061561 A3 WO2011061561 A3 WO 2011061561A3
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WIPO (PCT)
Prior art keywords
regeneration
tissue
matrices
guided
hard
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PCT/IB2009/055180
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English (en)
Spanish (es)
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WO2011061561A2 (fr
Inventor
Elda Restrepo
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Elda Restrepo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Elda Restrepo filed Critical Elda Restrepo
Priority to PCT/IB2009/055180 priority Critical patent/WO2011061561A2/fr
Publication of WO2011061561A2 publication Critical patent/WO2011061561A2/fr
Publication of WO2011061561A3 publication Critical patent/WO2011061561A3/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne un procédé destiné à obtenir des matrices moléculaires régénératrices qui induisent, par signalisation cellulaire, la différentiation sélective des cellules mères mésenchymateuses présentes dans tous les tissus conjonctifs. En outre, elle concerne la matrice obtenue au moyen de ce procédé, laquelle possède les propriétés régénératrices des tissus conjonctifs durs et mous avec des utilisations tant pour des êtres humains que pour des animaux. La matrice de l'invention est utile dans de multiples applications, entre autres, pour la régénération de tissus mous, tels que les muqueuses et la peau; la régénération de tissus durs, entre autres les os et le cartilage; la régénération épithéliale et la kératinisation; l'adhésion tissulaire, la cicatrisation, la conservation et l'implantation de cellules autologues ou cultivées, la diminution ou l'élimination de parenthèses post-chirurgicales, l'hémostase locale, la libération et le transfert local de molécules et de médicaments, de matrices bioabsorbables à effet barrière (régénération soit guidée, soit périodontique guidée), la néovascularisation et la revascularisation tissulaire, l'optimisation de ré-implantation de structures ou de tissus perdus par traumatisme, oséointégration prothésique, etc.
PCT/IB2009/055180 2009-11-19 2009-11-19 Procédé destiné à obtenir des matrices moléculaires régénératrices et matrices moléculaires régénératrices ainsi obtenues WO2011061561A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IB2009/055180 WO2011061561A2 (fr) 2009-11-19 2009-11-19 Procédé destiné à obtenir des matrices moléculaires régénératrices et matrices moléculaires régénératrices ainsi obtenues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2009/055180 WO2011061561A2 (fr) 2009-11-19 2009-11-19 Procédé destiné à obtenir des matrices moléculaires régénératrices et matrices moléculaires régénératrices ainsi obtenues

Publications (2)

Publication Number Publication Date
WO2011061561A2 WO2011061561A2 (fr) 2011-05-26
WO2011061561A3 true WO2011061561A3 (fr) 2012-08-23

Family

ID=44060120

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/055180 WO2011061561A2 (fr) 2009-11-19 2009-11-19 Procédé destiné à obtenir des matrices moléculaires régénératrices et matrices moléculaires régénératrices ainsi obtenues

Country Status (1)

Country Link
WO (1) WO2011061561A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5570111A1 (es) * 2005-04-13 2005-10-31 Elda Restrepo Nueva tecnica para obtener en una sola fase factores autolo- gos de crecimiento, trombina y fibrina, para ser aplicados en forma gelificada
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
ES2306655T3 (es) * 1999-01-26 2008-11-16 Eduardo Anitua Aldecoa Composicion para la regeneracion de tejido oseo.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
ES2306655T3 (es) * 1999-01-26 2008-11-16 Eduardo Anitua Aldecoa Composicion para la regeneracion de tejido oseo.
CO5570111A1 (es) * 2005-04-13 2005-10-31 Elda Restrepo Nueva tecnica para obtener en una sola fase factores autolo- gos de crecimiento, trombina y fibrina, para ser aplicados en forma gelificada

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DOHAN M. D. ET AL.: "Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF).", TRENDS IN BIOTECHNOLOGY., vol. 27, no. 3, 31 January 2009 (2009-01-31), pages 158 - 167, XP025958233, DOI: doi:10.1016/j.tibtech.2008.11.009 *
EPPLEY, B. ET AL.: "Platelet Quantification and Growth Factor Analysis from Platelet-Rich Plasma: Implications for Wound Healing.", PLASTIC AND RECONSTRUCTION SURGERY., vol. 114, November 2004 (2004-11-01), pages 1502 - 1508 *

Also Published As

Publication number Publication date
WO2011061561A2 (fr) 2011-05-26

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