WO2011059285A3 - 지노타이핑 방법 - Google Patents
지노타이핑 방법 Download PDFInfo
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- WO2011059285A3 WO2011059285A3 PCT/KR2010/008055 KR2010008055W WO2011059285A3 WO 2011059285 A3 WO2011059285 A3 WO 2011059285A3 KR 2010008055 W KR2010008055 W KR 2010008055W WO 2011059285 A3 WO2011059285 A3 WO 2011059285A3
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- genotyping
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/185—Modifications characterised by incorporating bases where the precise position of the bases in the nucleic acid string is important
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- C12Q2535/122—Massive parallel sequencing
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- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
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- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/30—Detection characterised by liberation or release of label
- C12Q2565/301—Pyrophosphate (PPi)
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
본 발명은 지노타이핑 방법에 관한 것으로, 더욱 자세하게는 지노타입별로 부여되는 ID 시퀀스 및 상기 ID 시퀀스를 이용한 다중지노타이핑 방법에 관한 것이다. 본 발명의 ID 시퀀스를 이용하여, 파이로시퀀싱을 수행할 경우 유전형마다 독특하면서도 간결한 파이로그램을 수득할 수 있어, 바이러스 유전자, 질병 유전자, 세균유전자 및 개인식별용 유전자들을 간단하면서도 효율적으로 지노타이핑할 수 있으며, 본 발명의 지노타이핑용 프라이머는 분배형식을 사용하는 모든 시퀀싱을 이용한 지노타이핑 방법에 다양하게 응용가능하다.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10830217.5A EP2522741B1 (en) | 2009-11-16 | 2010-11-15 | Genotyping method |
ES10830217.5T ES2542426T3 (es) | 2009-11-16 | 2010-11-15 | Método de genotipado |
US13/510,226 US20120276524A1 (en) | 2009-11-16 | 2010-11-15 | Genotyping method |
JP2012539806A JP2013510589A (ja) | 2009-11-16 | 2010-11-15 | ジェノタイピング方法 |
CN2010800615970A CN102741428A (zh) | 2009-11-16 | 2010-11-15 | 基因分型的方法 |
US14/811,396 US9695473B2 (en) | 2009-11-16 | 2015-07-28 | Genotyping method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2009-0110331 | 2009-11-16 | ||
KR20090110331 | 2009-11-16 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/510,226 A-371-Of-International US20120276524A1 (en) | 2009-11-16 | 2010-11-15 | Genotyping method |
US14/811,396 Division US9695473B2 (en) | 2009-11-16 | 2015-07-28 | Genotyping method |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011059285A2 WO2011059285A2 (ko) | 2011-05-19 |
WO2011059285A3 true WO2011059285A3 (ko) | 2011-10-06 |
Family
ID=43992257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2010/008055 WO2011059285A2 (ko) | 2009-11-16 | 2010-11-15 | 지노타이핑 방법 |
Country Status (7)
Country | Link |
---|---|
US (2) | US20120276524A1 (ko) |
EP (1) | EP2522741B1 (ko) |
JP (2) | JP2013510589A (ko) |
KR (1) | KR101183199B1 (ko) |
CN (2) | CN102741428A (ko) |
ES (1) | ES2542426T3 (ko) |
WO (1) | WO2011059285A2 (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106854682A (zh) * | 2016-12-27 | 2017-06-16 | 上海派森诺生物科技股份有限公司 | 一种利用基因对流感病毒进行分型的方法 |
CN109411018A (zh) * | 2019-01-23 | 2019-03-01 | 上海宝藤生物医药科技股份有限公司 | 根据基因突变信息对样本分类的方法、装置、设备及介质 |
CN114381518A (zh) * | 2020-10-05 | 2022-04-22 | 复旦大学附属华山医院 | 一种用于快速检测胶质瘤突变位点及分型的引物和试剂盒 |
CN112852937B (zh) * | 2021-03-10 | 2021-11-09 | 美格医学检验所(广州)有限公司 | 一种呼吸道病原微生物检测引物组合、试剂盒及其应用 |
Family Cites Families (13)
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US6004826A (en) * | 1988-07-20 | 1999-12-21 | David Segev | Repair-mediated process for amplifying and detecting nucleic acid sequences |
TWI316964B (ko) * | 2000-10-30 | 2009-11-11 | Takara Bio Inc | |
AU2002233540A1 (en) * | 2001-02-23 | 2002-09-12 | Pyrosequencing Ab | Allele-specific primer extension assay |
CN1678345A (zh) * | 2002-04-26 | 2005-10-05 | 米迪缪尼疫苗股份有限公司 | 制备流感病毒的多质粒系统 |
WO2005003375A2 (en) * | 2003-01-29 | 2005-01-13 | 454 Corporation | Methods of amplifying and sequencing nucleic acids |
US7393665B2 (en) * | 2005-02-10 | 2008-07-01 | Population Genetics Technologies Ltd | Methods and compositions for tagging and identifying polynucleotides |
US7407757B2 (en) * | 2005-02-10 | 2008-08-05 | Population Genetics Technologies | Genetic analysis by sequence-specific sorting |
EP1929039B2 (en) * | 2005-09-29 | 2013-11-20 | Keygene N.V. | High throughput screening of mutagenized populations |
WO2007149789A2 (en) * | 2006-06-22 | 2007-12-27 | Applera Corporation | Conversion of target specific amplification to universal sequencing |
US8603749B2 (en) | 2006-11-15 | 2013-12-10 | Biospherex, LLC | Multitag sequencing ecogenomics analysis-US |
US20090006002A1 (en) * | 2007-04-13 | 2009-01-01 | Sequenom, Inc. | Comparative sequence analysis processes and systems |
CN100540682C (zh) * | 2007-09-14 | 2009-09-16 | 东南大学 | 基于碱基修饰保护往复延伸的dna测序方法 |
CN102124125A (zh) * | 2007-10-16 | 2011-07-13 | 霍夫曼-拉罗奇有限公司 | 通过克隆性测序的高分辨率、高通量hla基因分型 |
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2010
- 2010-11-15 ES ES10830217.5T patent/ES2542426T3/es active Active
- 2010-11-15 KR KR1020100113193A patent/KR101183199B1/ko active IP Right Grant
- 2010-11-15 EP EP10830217.5A patent/EP2522741B1/en active Active
- 2010-11-15 CN CN2010800615970A patent/CN102741428A/zh active Pending
- 2010-11-15 US US13/510,226 patent/US20120276524A1/en not_active Abandoned
- 2010-11-15 CN CN201510016264.0A patent/CN104611423B/zh active Active
- 2010-11-15 JP JP2012539806A patent/JP2013510589A/ja active Pending
- 2010-11-15 WO PCT/KR2010/008055 patent/WO2011059285A2/ko active Application Filing
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2015
- 2015-04-20 JP JP2015085531A patent/JP6026589B2/ja active Active
- 2015-07-28 US US14/811,396 patent/US9695473B2/en active Active
Non-Patent Citations (4)
Title |
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AYDIN, A. ET AL.: "New universal primers facilitate Pyrosequencing", ELECTROPHORESIS, vol. 27, no. 2, February 2006 (2006-02-01), pages 394 - 397 * |
MOHAMED, M. F. ET AL.: "Interpopulation variation frequency of human inosine 5'- monophosphate dehydrogenase type II (IMPDH2) genetic polymorphisms", GENET. TEST, vol. 12, no. 4, December 2008 (2008-12-01), pages 513 - 516 * |
RINGQUIST, S. ET AL.: "Web-based primer design software for genome-scale genotyping by pyrosequencing", METHODS MOL. BIOL., vol. 373, 2007, pages 25 - 38 * |
TRAMA, J.P. ET AL.: "Identification and genotyping of molluscum contagiosum virus from genital swab samples by real-time PCR and Pyrosequencing", J. CLIN. VIROL., vol. 40, no. 4, December 2007 (2007-12-01), pages 325 - 329, XP022362134, DOI: doi:10.1016/j.jcv.2007.09.007 * |
Also Published As
Publication number | Publication date |
---|---|
JP2013510589A (ja) | 2013-03-28 |
CN104611423B (zh) | 2018-03-20 |
ES2542426T3 (es) | 2015-08-05 |
WO2011059285A2 (ko) | 2011-05-19 |
CN104611423A (zh) | 2015-05-13 |
US20120276524A1 (en) | 2012-11-01 |
US20150322509A1 (en) | 2015-11-12 |
US9695473B2 (en) | 2017-07-04 |
JP6026589B2 (ja) | 2016-11-16 |
EP2522741A2 (en) | 2012-11-14 |
JP2015163075A (ja) | 2015-09-10 |
KR101183199B1 (ko) | 2012-09-14 |
EP2522741A4 (en) | 2013-05-22 |
KR20110053911A (ko) | 2011-05-24 |
CN102741428A (zh) | 2012-10-17 |
EP2522741B1 (en) | 2015-04-15 |
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