WO2011056006A3 - 페이스트-분말의 이원성 고분자계 골 시멘트 및 이의 투입장치 - Google Patents

페이스트-분말의 이원성 고분자계 골 시멘트 및 이의 투입장치 Download PDF

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Publication number
WO2011056006A3
WO2011056006A3 PCT/KR2010/007774 KR2010007774W WO2011056006A3 WO 2011056006 A3 WO2011056006 A3 WO 2011056006A3 KR 2010007774 W KR2010007774 W KR 2010007774W WO 2011056006 A3 WO2011056006 A3 WO 2011056006A3
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WO
WIPO (PCT)
Prior art keywords
paste
bone cement
based bone
same
relates
Prior art date
Application number
PCT/KR2010/007774
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English (en)
French (fr)
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WO2011056006A2 (ko
Inventor
심재범
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(주)인젝타
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Priority to CN201080054011.8A priority Critical patent/CN102639157B/zh
Priority to US13/142,338 priority patent/US10016526B2/en
Priority to EP10828541.2A priority patent/EP2497504B1/en
Publication of WO2011056006A2 publication Critical patent/WO2011056006A2/ko
Publication of WO2011056006A3 publication Critical patent/WO2011056006A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)

Abstract

본 발명은 인공 관절 치환술(arthroplasty)이나 척추 성형술 (vertebro plasty)에서 사용되는 고분자계 골시멘트에 관한 것으로, 보다 구체적으로는 분말성분들 중 화학반응을 일으키지 않는 일정 분말 성분들을 액상의 모노머에 용해시켜 점성을 페이스트로 끌어올려 준비하고, 시술시에 나머지 분말성분들을 페이스트와 최소의 공기 노출로 혼합하여 추가 점착 시간 없이 시술부위에 바로 사용할 수 있는 페이스트-분말의 이원성 고분자계 골 시멘트 및 이의 투입장치에 관한 것이다.
PCT/KR2010/007774 2009-11-06 2010-11-04 페이스트-분말의 이원성 고분자계 골 시멘트 및 이의 투입장치 WO2011056006A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201080054011.8A CN102639157B (zh) 2009-11-06 2010-11-04 糊膏-粉末双聚合物基骨水泥
US13/142,338 US10016526B2 (en) 2009-11-06 2010-11-04 Paste-powder dual polymer-based bone cement and injection apparatus for same
EP10828541.2A EP2497504B1 (en) 2009-11-06 2010-11-04 Paste-powder dual polymer-based bone cement and injection apparatus for same

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20090106948 2009-11-06
KR10-2009-0106948 2009-11-06
KR10-2010-0107656 2010-11-01
KR1020100107656A KR101031864B1 (ko) 2009-11-06 2010-11-01 페이스트-분말의 이원성 고분자계 골 시멘트 및 이의 투입장치

Publications (2)

Publication Number Publication Date
WO2011056006A2 WO2011056006A2 (ko) 2011-05-12
WO2011056006A3 true WO2011056006A3 (ko) 2011-11-03

Family

ID=44365403

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/007774 WO2011056006A2 (ko) 2009-11-06 2010-11-04 페이스트-분말의 이원성 고분자계 골 시멘트 및 이의 투입장치

Country Status (5)

Country Link
US (1) US10016526B2 (ko)
EP (1) EP2497504B1 (ko)
KR (1) KR101031864B1 (ko)
CN (1) CN102639157B (ko)
WO (1) WO2011056006A2 (ko)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
DE102014105267A1 (de) * 2014-04-14 2015-10-15 Heraeus Medical Gmbh Polymethylmethacrylat-Knochenzement
US9180226B1 (en) * 2014-08-07 2015-11-10 Cook Medical Technologies Llc Compositions and devices incorporating water-insoluble therapeutic agents and methods of the use thereof
US11241520B2 (en) 2014-08-07 2022-02-08 Cook Medical Technologies Llc Compositions and devices incorporating water-insoluble therapeutic agents and methods of the use thereof
DE102015217315A1 (de) * 2015-09-10 2017-03-16 Heraeus Medical Gmbh Polymethylmethacrylat-Knochenzement mit einstellbarer initialer Viskosität und ein Verfahren zur Herstellung eines Knochenzementteigs mit variabler initialer Viskosität
DE102016208567A1 (de) 2016-05-19 2017-11-23 Heraeus Medical Gmbh Polymerlösung zur Viscosupplementation
DE102016209988A1 (de) 2016-06-07 2017-12-07 Heraeus Medical Gmbh Pastenförmiger Zweikomponenten-Polymethylmethacrylat-Knochenzement
DE102016222158A1 (de) * 2016-11-11 2018-05-17 Heraeus Medical Gmbh Verfahren zur Herstellung eines Polymethylmethacrylat-Knochenzements, Knochenzement-Kit zur Verwendung in einem solchen Verfahren und ein durch ein solches Verfahren herstellbarer Knochenzement
CN114514066A (zh) * 2019-12-27 2022-05-17 狮王株式会社 膏糊状制剂的制备系统和膏糊状制剂的制备方法
CN112957524B (zh) * 2021-02-24 2022-05-17 北京邦塞科技有限公司 骨水泥及其制备方法和应用

Citations (5)

* Cited by examiner, † Cited by third party
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US5114240A (en) * 1989-05-12 1992-05-19 Wolff & Kaaber A/S Method and a device for preparing a mixture of a solid and a liquid component
JPH06261932A (ja) * 1989-12-29 1994-09-20 Tecres Spa 骨セメントの混合と埋め込み方法およびそのための器具
EP1886648A1 (en) * 2006-08-11 2008-02-13 Biomet Cementing Technologies AB Device at bone cement mixer
US7569621B2 (en) * 2005-07-07 2009-08-04 Heraeus Kulzer Gmbh Dyed polymethyl methacrylate bone cement and process for its production
KR100957543B1 (ko) * 2008-01-28 2010-05-11 연세대학교 산학협력단 비정질 칼슘 포스페이트를 함유하는 골대체용 조성물

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FR2516796B1 (fr) 1981-11-20 1986-06-06 Altulor Sa Compositions pour ciment chirurgical a base d'au moins un monomere acrylique et d'au moins un polymere acrylique
US5819988A (en) * 1997-04-01 1998-10-13 Sawhney; Ravi K. Double-barreled syringe with detachable locking mixing tip
US6593394B1 (en) * 2000-01-03 2003-07-15 Prosperous Kingdom Limited Bioactive and osteoporotic bone cement
WO2005069837A2 (en) * 2004-01-13 2005-08-04 Royer Biomedical, Inc. Non-aqueous compositions for treatment of orthopedic defects and delivery of bioactive agents
FR2870129A1 (fr) * 2004-05-14 2005-11-18 Ceravic Sas Soc Par Actions Si Ciment polymere pour la vertebroplastie percutanee
DE102004049121B4 (de) * 2004-10-07 2008-01-10 Heraeus Kulzer Gmbh Antibiotikum-/Antibiotika enthaltender PMMA-Knochenzement
US7754005B2 (en) * 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
US8575274B2 (en) * 2006-07-17 2013-11-05 Syracuse University Multi-solution bone cements and methods of making the same
DE102007050763A1 (de) * 2007-10-22 2009-04-23 Heraeus Medical Gmbh Initiatorsystem für selbsthärtende Kunststoffe, seine Verwendung und es enthaltende Knochenzementzusammensetzungen
DE102007050762B3 (de) * 2007-10-22 2009-05-07 Heraeus Medical Gmbh Pastenförmiger Polymethylmethacrylat-Knochenzement und seine Verwendung
WO2009097152A1 (en) * 2008-01-31 2009-08-06 The United States Of America As Represented By The Secretary Of The Navy Multifunctional acrylates used as cross-linkers in dental and biomedical self-etching bonding adhesives

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114240A (en) * 1989-05-12 1992-05-19 Wolff & Kaaber A/S Method and a device for preparing a mixture of a solid and a liquid component
JPH06261932A (ja) * 1989-12-29 1994-09-20 Tecres Spa 骨セメントの混合と埋め込み方法およびそのための器具
US7569621B2 (en) * 2005-07-07 2009-08-04 Heraeus Kulzer Gmbh Dyed polymethyl methacrylate bone cement and process for its production
EP1886648A1 (en) * 2006-08-11 2008-02-13 Biomet Cementing Technologies AB Device at bone cement mixer
KR100957543B1 (ko) * 2008-01-28 2010-05-11 연세대학교 산학협력단 비정질 칼슘 포스페이트를 함유하는 골대체용 조성물

Also Published As

Publication number Publication date
CN102639157A (zh) 2012-08-15
EP2497504A2 (en) 2012-09-12
US20110270259A1 (en) 2011-11-03
WO2011056006A2 (ko) 2011-05-12
KR101031864B1 (ko) 2011-05-02
EP2497504A4 (en) 2014-06-04
US10016526B2 (en) 2018-07-10
CN102639157B (zh) 2014-08-13
EP2497504B1 (en) 2019-01-09

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