WO2011054995A3 - Vaccins prophylactiques contre la grippe obtenus à partir de capsides virales de birnavirus contenant l'antigène m2e du virus de la grippe - Google Patents
Vaccins prophylactiques contre la grippe obtenus à partir de capsides virales de birnavirus contenant l'antigène m2e du virus de la grippe Download PDFInfo
- Publication number
- WO2011054995A3 WO2011054995A3 PCT/ES2010/070716 ES2010070716W WO2011054995A3 WO 2011054995 A3 WO2011054995 A3 WO 2011054995A3 ES 2010070716 W ES2010070716 W ES 2010070716W WO 2011054995 A3 WO2011054995 A3 WO 2011054995A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- flu
- birnavirus
- antigen
- prophylactic
- vaccines
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne des vaccins prophylactiques pour la prévention de la grippe chez les êtres humains. En particulier, les vaccins de la présente invention sont formés de capsides pseudo-virales chimériques de birnavirus contenant l'antigène M2e du virus de la grippe.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP200930968 | 2009-11-06 | ||
ES200930968 | 2009-11-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011054995A2 WO2011054995A2 (fr) | 2011-05-12 |
WO2011054995A3 true WO2011054995A3 (fr) | 2011-06-30 |
Family
ID=43806896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ES2010/070716 WO2011054995A2 (fr) | 2009-11-06 | 2010-11-05 | Vaccins prophylactiques contre la grippe obtenus à partir de capsides virales de birnavirus contenant l'antigène m2e du virus de la grippe |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011054995A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013059168A2 (fr) * | 2011-10-21 | 2013-04-25 | Research Development Foundation | Virus espirito santo et procédés de détection et de prévention d'une infection par ledit virus |
CN103083656A (zh) * | 2011-10-27 | 2013-05-08 | 苏州科贝生物技术有限公司 | 甲型流感病毒保守肽M2e与病毒样颗粒的缀合物及应用 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0887412A1 (fr) * | 1997-05-26 | 1998-12-30 | Akzo Nobel N.V. | Vaccin recombinant du birnavirus |
WO2002088339A2 (fr) * | 2001-05-02 | 2002-11-07 | Institut National De La Recherche Agronomique (Inra) | Particules pseudovirales de birnavirus |
WO2007009673A1 (fr) * | 2005-07-15 | 2007-01-25 | Consejo Superior De Investigaciones Científicas | Particules chimeriques vides d'apparence virale tirees du virus de la bursite infectieuse (ibdv), procede de production et applications |
EP1752468A1 (fr) * | 2004-04-30 | 2007-02-14 | Consejo Superior de Investigaciones Cientificas | Procede de production de capsules virales vides en levure composees de proteines derivees de pvp2 du virus entrainant la maladie de la bursite infectieuse (ibdv) |
WO2007020017A1 (fr) * | 2005-08-12 | 2007-02-22 | Bionostra, S.L. | Composition destinee a l'immunisation des oiseaux et administree par aerosol |
WO2009026465A2 (fr) * | 2007-08-21 | 2009-02-26 | Dynavax Technologies Corporation | Composition et procédés de fabrication et d'utilisation de protéines de la grippe |
WO2009135518A1 (fr) * | 2008-05-09 | 2009-11-12 | Chimera Pharma S.L.U. | Protéines de fusion chimères et particules de type viral de birnavirus vp2 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2297786C (fr) | 1997-08-05 | 2011-06-14 | Vlaams Interuniversitair Instituut Voor Biotechnologie | Nouvel antigene immunoprotecteur contre la grippe a et son utilisation dans la vaccination |
-
2010
- 2010-11-05 WO PCT/ES2010/070716 patent/WO2011054995A2/fr active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0887412A1 (fr) * | 1997-05-26 | 1998-12-30 | Akzo Nobel N.V. | Vaccin recombinant du birnavirus |
WO2002088339A2 (fr) * | 2001-05-02 | 2002-11-07 | Institut National De La Recherche Agronomique (Inra) | Particules pseudovirales de birnavirus |
EP1752468A1 (fr) * | 2004-04-30 | 2007-02-14 | Consejo Superior de Investigaciones Cientificas | Procede de production de capsules virales vides en levure composees de proteines derivees de pvp2 du virus entrainant la maladie de la bursite infectieuse (ibdv) |
WO2007009673A1 (fr) * | 2005-07-15 | 2007-01-25 | Consejo Superior De Investigaciones Científicas | Particules chimeriques vides d'apparence virale tirees du virus de la bursite infectieuse (ibdv), procede de production et applications |
WO2007020017A1 (fr) * | 2005-08-12 | 2007-02-22 | Bionostra, S.L. | Composition destinee a l'immunisation des oiseaux et administree par aerosol |
WO2009026465A2 (fr) * | 2007-08-21 | 2009-02-26 | Dynavax Technologies Corporation | Composition et procédés de fabrication et d'utilisation de protéines de la grippe |
WO2009135518A1 (fr) * | 2008-05-09 | 2009-11-12 | Chimera Pharma S.L.U. | Protéines de fusion chimères et particules de type viral de birnavirus vp2 |
Non-Patent Citations (3)
Title |
---|
LETZEL TOBIAS ET AL: "Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 81, no. 23, 1 December 2007 (2007-12-01), pages 12827 - 12835, XP002514417, ISSN: 0022-538X, [retrieved on 20070919], DOI: DOI:10.1128/JVI.01501.07 * |
REMOND M ET AL: "Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site", VACCINE, ELSEVIER LTD, GB, vol. 27, no. 1, 1 January 2009 (2009-01-01), pages 93 - 98, XP025714114, ISSN: 0264-410X, [retrieved on 20081105], DOI: DOI:10.1016/J.VACCINE.2008.10.036 * |
VAN LOON A A W M ET AL: "Alteration of amino acids in VP2 of very virulent infectious bursal disease virus results in tissue culture adaptation and attenuation in chickens", JOURNAL OF GENERAL VIROLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, SPENCERS WOOD, GB, vol. 83, no. 1, 1 January 2002 (2002-01-01), pages 121 - 129, XP002514415, ISSN: 0022-1317 * |
Also Published As
Publication number | Publication date |
---|---|
WO2011054995A2 (fr) | 2011-05-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HRP20180706T1 (hr) | Kimerna gripa nalik čestici koja sadrži hemaglutinin | |
PT2121011E (pt) | Vacinas compreendendo um antigénio a partir de quatro estirpes do vírus da gripe | |
AP2012006075A0 (en) | Production of polio virus at high titers for vaccine production. | |
IL210451A (en) | Epitope for influenza virus vaccine | |
WO2011103453A3 (fr) | Vaccins destinés à être utilisés pour la prophylaxie et le traitement d'une maladie liée au virus de la grippe | |
IN2014CN02114A (fr) | ||
BRPI0912285A2 (pt) | anticorpos monoclonais tendo propriedades de neutralização cruzada de homosubtipo contra o vírus influenza subtipo h1. | |
MX352478B (es) | Proteina vp6 de la capside de norovirus y rotavirus para el uso como vacuna combinada. | |
PT2635257T (pt) | Partículas semelhantes a vírus de glicoproteína de raiva (vlps) | |
HK1203524A1 (en) | Computationally optimized broadly reactive antigens for h3n2, h2n2, and b influenza viruses h3n2h2n2 b | |
ZA201401020B (en) | Benzofuran compounds for the treatment of hepatitis c virus infections | |
WO2012137227A3 (fr) | Formes solides de composés antirétroviraux, procédé de préparation correspondant et composition pharmaceutique de ces composés | |
BRPI1007584A2 (pt) | vacina de sarampo-malária combinada, vetor de vírus de vacina de sarampo, hospedeiro e composição de vacina de sarampo-malária combinada | |
WO2014145245A3 (fr) | Procédés et compositions pour des épitopes de blocage de norovirus | |
EP2897628A4 (fr) | Nouvelles souches atténuées du virus de la dengue destinées à une application de vaccin | |
WO2012058493A3 (fr) | Protéine d'hémagglutinine recombinante du virus de la grippe et vaccin la contenant | |
EP2484757A4 (fr) | Virus capable d'exprimer un épitope de -galactose, et procédé de production de vaccin | |
WO2011054995A3 (fr) | Vaccins prophylactiques contre la grippe obtenus à partir de capsides virales de birnavirus contenant l'antigène m2e du virus de la grippe | |
WO2014008475A3 (fr) | Compositions et procédés associés à des vaccins viraux | |
SG11201403773WA (en) | Monoclonal antibodies targeting neutralizing epitopes on h5 influenza virus of clade 2.3 | |
EP3247390A4 (fr) | Immunogénicité d'un vaccin à adn consensus synthétique optimisé pour le virus de la diarrhée épidémique porcine | |
WO2009117736A3 (fr) | Vaccins contre virus aviaires et leurs utilisations | |
WO2014188212A3 (fr) | Traitement et prévention du paludisme | |
TH1201001748B (th) | ส่วนสร้างที่สามารถผลิตแคปสิดเปล่าของไวรัส | |
TH112917B (th) | โปรตีนให้การเชื่อมจับ และ elisa ทำการบล็อค-อีพิโทปสำหรับการตรวจหาโดยทั่วไปของไวรัสไข้หวัดใหญ่ประเภทย่อย h5 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 10809272 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
32PN | Ep: public notification in the ep bulletin as address of the adressee cannot be established |
Free format text: NOTING OF LOSSS OF RIGHTS PURSUANT TO RULE 112(1) EPC |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 10809272 Country of ref document: EP Kind code of ref document: A2 |