SG11201403773WA - Monoclonal antibodies targeting neutralizing epitopes on h5 influenza virus of clade 2.3 - Google Patents
Monoclonal antibodies targeting neutralizing epitopes on h5 influenza virus of clade 2.3Info
- Publication number
- SG11201403773WA SG11201403773WA SG11201403773WA SG11201403773WA SG11201403773WA SG 11201403773W A SG11201403773W A SG 11201403773WA SG 11201403773W A SG11201403773W A SG 11201403773WA SG 11201403773W A SG11201403773W A SG 11201403773WA SG 11201403773W A SG11201403773W A SG 11201403773WA
- Authority
- SG
- Singapore
- Prior art keywords
- clade
- monoclonal antibodies
- influenza virus
- antibodies targeting
- neutralizing epitopes
- Prior art date
Links
- 230000003472 neutralizing effect Effects 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
- 241000712461 unidentified influenza virus Species 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/SG2012/000012 WO2013105896A1 (en) | 2012-01-12 | 2012-01-12 | Monoclonal antibodies targeting neutralizing epitopes on h5 influenza virus of clade 2.3 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201403773WA true SG11201403773WA (en) | 2014-07-30 |
Family
ID=48781737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201403773WA SG11201403773WA (en) | 2012-01-12 | 2012-01-12 | Monoclonal antibodies targeting neutralizing epitopes on h5 influenza virus of clade 2.3 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9233152B2 (en) |
| CN (1) | CN104169297B (en) |
| SG (1) | SG11201403773WA (en) |
| WO (1) | WO2013105896A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170306001A1 (en) * | 2014-03-27 | 2017-10-26 | National University Of Singapore | Chimerization and characterization of a monoclonal antibody with potent neutralizing activity across multiple influenza a h5n1 clades |
| KR101849101B1 (en) | 2016-07-28 | 2018-04-17 | 원광대학교산학협력단 | Monoclonal antibody specific to hemagglutinin of H5 subtype influenza virus and rapid fluorescence-linked immunochromatographic diagnostic kit using the same |
| PL238020B1 (en) * | 2016-09-12 | 2021-06-28 | Inst Biotechnologii I Antybiotykow | Monoclonal antibodies against haemagglutinin of influenza serotype H5 viruses and their applications, hybridomas that produce mentioned antibodies, compositions and diagnostic sets |
| JP6824026B2 (en) * | 2016-12-24 | 2021-02-03 | 株式会社タウンズ | Influenza virus H5 subtype immunoassay |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102046654A (en) | 2007-03-13 | 2011-05-04 | 胡马斯有限公司 | Antibodies against H5N1 strains of influenza a virus |
| EP2201039B1 (en) * | 2007-09-13 | 2015-07-15 | Temasek Life Sciences Laboratory Limited | Monoclonal antibodies specific to hemagglutinin and neuraminidase from influenza virus h5-subtype or n1-subtype and uses thereof |
-
2012
- 2012-01-12 CN CN201280071324.3A patent/CN104169297B/en active Active
- 2012-01-12 US US14/369,576 patent/US9233152B2/en active Active
- 2012-01-12 WO PCT/SG2012/000012 patent/WO2013105896A1/en active Application Filing
- 2012-01-12 SG SG11201403773WA patent/SG11201403773WA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9233152B2 (en) | 2016-01-12 |
| US20140314777A1 (en) | 2014-10-23 |
| CN104169297A (en) | 2014-11-26 |
| WO2013105896A9 (en) | 2016-02-11 |
| CN104169297B (en) | 2018-06-01 |
| WO2013105896A1 (en) | 2013-07-18 |
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