WO2011036680A3 - Improved process for preparation of (±)-1-(1-benzo[b]thien-2-ylethyl)-1-hydroxyurea - Google Patents
Improved process for preparation of (±)-1-(1-benzo[b]thien-2-ylethyl)-1-hydroxyurea Download PDFInfo
- Publication number
- WO2011036680A3 WO2011036680A3 PCT/IN2010/000640 IN2010000640W WO2011036680A3 WO 2011036680 A3 WO2011036680 A3 WO 2011036680A3 IN 2010000640 W IN2010000640 W IN 2010000640W WO 2011036680 A3 WO2011036680 A3 WO 2011036680A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ylethyl
- thien
- benzo
- preparation
- hydroxyurea
- Prior art date
Links
- MWLSOWXNZPKENC-UHFFFAOYSA-N zileuton Chemical compound C1=CC=C2SC(C(N(O)C(N)=O)C)=CC2=C1 MWLSOWXNZPKENC-UHFFFAOYSA-N 0.000 title 1
- -1 (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
An improved process for the preparation of (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea compound of formula (I).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2307CH2009 | 2009-09-23 | ||
IN2307/CHE/2009 | 2009-09-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011036680A2 WO2011036680A2 (en) | 2011-03-31 |
WO2011036680A3 true WO2011036680A3 (en) | 2011-05-19 |
Family
ID=43796318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2010/000640 WO2011036680A2 (en) | 2009-09-23 | 2010-09-22 | Improved process for the preparation of (±)-1-(1-benzo[b]thien-2-ylethyl)-1-hydroxyurea |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011036680A2 (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20080888A1 (en) * | 2008-05-15 | 2009-11-16 | Dipharma Francis Srl | PROCEDURE FOR THE PREPARATION OF ZILEUTON |
-
2010
- 2010-09-22 WO PCT/IN2010/000640 patent/WO2011036680A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20080888A1 (en) * | 2008-05-15 | 2009-11-16 | Dipharma Francis Srl | PROCEDURE FOR THE PREPARATION OF ZILEUTON |
Non-Patent Citations (1)
Title |
---|
CHARD R. COPP ET AL.: "ACID-CATALYZED ADDITION OF N-HYDROXYUREA TO 1 -ARYL AL ALCOHOL DERIVATIVES: A NEW SYNTHESIS OF ZILEUTON", SYNTHETIC COMMUNICATIONS, vol. 31, no. 20, 2001, pages 3081 - 3086 * |
Also Published As
Publication number | Publication date |
---|---|
WO2011036680A2 (en) | 2011-03-31 |
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