WO2011005165A1 - Cathéter et procédé de fabrication d'un tel cathéter - Google Patents

Cathéter et procédé de fabrication d'un tel cathéter Download PDF

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Publication number
WO2011005165A1
WO2011005165A1 PCT/SE2010/000186 SE2010000186W WO2011005165A1 WO 2011005165 A1 WO2011005165 A1 WO 2011005165A1 SE 2010000186 W SE2010000186 W SE 2010000186W WO 2011005165 A1 WO2011005165 A1 WO 2011005165A1
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
conductor
plug
hole
electrode
Prior art date
Application number
PCT/SE2010/000186
Other languages
English (en)
Inventor
Bengt KÄLLBÄCK
Malin Thomsen
Original Assignee
Cathprint Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cathprint Ab filed Critical Cathprint Ab
Publication of WO2011005165A1 publication Critical patent/WO2011005165A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • A61M25/0012Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • A61M25/0015Making lateral openings in a catheter tube, e.g. holes, slits, ports, piercings of guidewire ports; Methods for processing the holes, e.g. smoothing the edges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/005Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05KPRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
    • H05K3/00Apparatus or processes for manufacturing printed circuits
    • H05K3/40Forming printed elements for providing electric connections to or between printed circuits
    • H05K3/42Plated through-holes or plated via connections
    • H05K3/423Plated through-holes or plated via connections characterised by electroplating method

Definitions

  • the present invention is related to a catheter and a method for manufacturing such a catheter according to the preamble of the independent claims.
  • Catheters with electrodes that are connected to conductors, which extend along the lengths of the catheters, are known.
  • the document US6856822 describes a catheter with lumens that extend along the catheter. Electric conductors are arranged in these lumens, from each of which a hole extends orthogonally through the catheter walls to the outer surface of the catheter.
  • conducting rings Around the catheter are arranged conducting rings that act as electrodes and these are connected to the conductors inside the lumens through the holes in the catheter wall.
  • the electrical connection between the conducting rings and the internal conductors is made with an element which fills the hole. Each such element must typically be manually created and treated individually.
  • One purpose of the invention is therefore to provide a catheter and a method for manufacturing such a catheter that enables the electrical connection element to be created in the catheter in a simple way.
  • Another purpose of the invention is to provide a catheter and a method for manufacturing such a catheter that enables the simultaneous production of multiple electrical connection elements on a catheter.
  • the invention concerns a catheter with at least one external electrode 6, 6a-c arranged on the outside of the catheter.
  • An external electrode is electrically connected to an internal conductor 4a, b, which extends along at least part of the length of the catheter and is electrically connected to an electrical conductor element 5a, b.
  • Holes 7a, b are arranged on the outer surface of the catheter and extend through the catheter walls to the internal conductor element 5a, b.
  • a conducting plug 8 is built into the hole 7, 7a, 7b.
  • Electroplating is the most advantageous method of creating this plug. This process can be monitored and controlled electrically using the connections to the conductors at the proximal catheter end. This system will make it possible to check which plugs have been created as an electric connection will signify a completed plug. In addition, this procedure results in a connection between the internal and external electrodes that is mechanically and electrically more stable than one provided by, for example, conductive epoxy.
  • a particularly advantageous embodiment is a catheter with at least one lumen 2b that extends along the length of the catheter in the direction in which a conductor or a conductor carrier is arranged.
  • the conductor carrier 3 may comprise a long flexible printed circuit board rolled about its longitudinal axis, with at least one conductor printed on the flexible printed circuit board.
  • the invention concerns the method of manufacturing such catheters, which includes a step where the conducting plug 8 is created in the hole 7, 7a, 7b on top of the internal electrodes 5a, b, typically by electroplating.
  • Fig. 1 shows a catheter to which the invention can be applied.
  • Fig. 2 shows the first step in manufacturing the first embodiment of the invention.
  • Fig. 3 shows the second step in manufacturing the first embodiment of the invention.
  • Fig. 4 shows the third step in manufacturing the first embodiment of the invention.
  • Fig. 5 shows the first step in manufacturing the second embodiment of the invention.
  • Fig. 6 shows the second step in manufacturing the second embodiment of the invention. Description of preferred embodiments
  • Fig. 1 shows a catheter with a design that is suitable for the application of the invention.
  • the catheter comprises a shaft 1 of a flexible material with two lumens with circular cross-sections that run along the length of the shaft.
  • the first lumen 2a has a larger cross-section than the other lumen 2b.
  • the first lumen may be intended for the delivery of liquid or gas and is empty in the figure.
  • a flexible electrical conductor carrier is inserted into the second lumen.
  • the conductor carrier 3 is designed as a narrow, rectangular, flexible printed circuit board, which is rolled into a tube along most of its length. The rolled portion of the flexible printed circuit board is filled with an adhesive which is flexible in its hardened state.
  • the flexible printed circuit board is the narrow tube which is inserted into the second lumen.
  • the flexible printed circuit board is double-sided. On the side that becomes the inner side of the tube lie conductors along the length of the board. At the upper end of the board, which extends slightly beyond the upper end of the catheter, the board is not rolled into a tube but flat. On this flat portion are conductors that can be connected electronic equipment. Each conductor measures a unique length from the end of the board, and the opposite ends connect to the internal electrodes 5a and 5b.
  • the internal electrodes 5a, b are arranged on the other side of the double- sided board, which becomes the outer side of the tube when the board is rolled.
  • each conductor in the form of a wire, is pulled through the catheter lumen, out the appropriate hole in the catheter wall and individually connected to a conducting ring that acted as the external electrode.
  • electrical contact is achieved separately for each external and internal electrode pair in a single step.
  • other types of conductors may be used with the invention, but the invention is particularly beneficial in the example described here involving a conductor carrier.
  • the external electrodes can be used for sensing purposes or for applying electric currents for various medical purposes.
  • the electrodes 5a, b, 6a, b though illustrated as annular elements in the figures, can also be designed in other shapes. The advantage of annular elements is that electrical contact is achieved regardless of how they are rotated with respect to the rest of the catheter.
  • Fig. 2 shows in greater detail a cross-section through a catheter in the first step in manufacturing the first embodiment of the invention.
  • This cross-section is taken through one of the holes 7, which is visible in this figure as an opening in the otherwise circular catheter.
  • the hole 7 extends to the second lumen 2b, which is separate from the first lumen 2a.
  • the conductor carrier 3 is arranged in lumen 2b.
  • the conductor carrier is round in shape and fills the most of the lumen.
  • Around the outer surface of the conductor carrier is an internal electrode, which is exposed through the hole 7.
  • Fig. 3 shows the second step in manufacturing the first embodiment of the invention in which the electroplating metal has been created to make contact with the inner electrode.
  • the metal layer is built up until the entire hole 7 has been filled, resulting in a plug 8.
  • the plug 8 extends to the outer surface of the catheter and is electrically connected to the internal electrode.
  • Electroplating is carried out by immersing the catheter in an electrolyte with metal ions. Then electrical power is supplied to the conductors on the conductor carrier that are connected to the internal electrodes on which the metal plug will be built. Providing power to all conductors will result in plugs being created simultaneously on all the internal electrodes. Plugs can be created individually to achieve different metals or heights as needed by controlling the power supply to respective conductors in the electroplating process.
  • the plugs are naturally built from the part of the internal electrode exposed by the hole 7 and adopt the shape of the hole.
  • the plug maintains connection with the internal electrode at all times and no connection problems can arise from a gap between the internal electrode and the plug.
  • Fig. 4 shows the third step in manufacturing the first embodiment of the invention.
  • a separate metal ring 6 is placed over the catheter so that it rests on the plug 8. Since the catheter material is flexible, the ring 6 can be swaged so that its inner diameter is smaller than the outer diameter of the catheter in the unloaded state. The ring will naturally then be pressed against the plug, achieving electric contact. In an embodiment not illustrated here, the plug is created so that it extends beyond the outer surface of the catheter.
  • a ring 6 can be fixed in place over the plug to make a connection with the internal electrode 5, providing an indication that can be felt by touch that the ring is in position.
  • Fig. 5 shows the first step in manufacturing the second embodiment of the invention.
  • the external electrode 6c which is not a separate and removable element as is the case in the first embodiment. Instead, the ring is applied on the catheter using one of several possible methods.
  • a possible application method involves spray or brush painting of conducting paint, moulding or plating with metal or another conducting material.
  • a plating method that can be used is described in EP0985333B1. This provides a layer of metal applied to the catheter in the desired shape of the electrode. Whichever application is used, the external electrode material must cover not only the outer surface of the catheter but also reach into the hole 7 to make contact with the exposed internal electrode.
  • the strength of the external electrode connection is limited when applied as a thin metal layer. In particular, it is possible that the joint between the internal electrode and the plug will become damaged, resulting in no electrical contact between the two elements. Another critical point is the joint between the plug and the external electrode.
  • Fig. 6 shows the second step in manufacturing the second embodiment of the invention.
  • a plug 8 is created in the hole according to the electroplating step in the first embodiment.
  • the metal plug fills the hole, growing on top of the metal layer that is the internal electrode.
  • the plug forms a continuous layer of metal elements and is connected mechanically and electrically to the internal electrode.
  • the plug guarantees electrical connection between the external and internal electrodes. In addition, it provides improved stability and strength to prevent mechanical failure.
  • the external electrode When the plug is created by electroplating, the external electrode is achieved in the same process by building a thicker layer of metal. After the electroplating process has been carried out for as long as it takes to achieve a stable electrical connection between the internal electrode and the deposited external electrode, the external electrode will continue grow at the same rate as the plug.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention porte sur un cathéter avec au moins une électrode externe (6, 6a-c) agencée sur la surface externe du cathéter. L'électrode externe est connectée à un conducteur (4a, b), qui s'étend le long d'au moins une partie de la longueur intérieure du cathéter et est électriquement connectée à une électrode interne (5a, b). Un trou (7, 7a, b) est pratiqué sur la surface externe du cathéter pour exposer l'électrode interne (5a, 5b). Sur l'électrode interne (5a, 5b), une prise conductrice (8) est construite pour remplir le trou (7, 7a, 7b). Plusieurs prises peuvent être créées simultanément sans traitement manuel individuel. La prise est typiquement créée par électroplacage, ce qui permet à la construction d'être commandée électriquement par la connexion électrique à l'extrémité du conducteur correspondant, qui est à l'extrémité proximale du cathéter. L'invention porte sur une connexion mécanique et électrique stable sur les électrodes externes du cathéter.
PCT/SE2010/000186 2009-07-06 2010-07-01 Cathéter et procédé de fabrication d'un tel cathéter WO2011005165A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0900936-6 2009-07-06
SE0900936A SE533762C2 (sv) 2009-07-06 2009-07-06 Kateter och metod för tillverkning av sådan kateter

Publications (1)

Publication Number Publication Date
WO2011005165A1 true WO2011005165A1 (fr) 2011-01-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE2010/000186 WO2011005165A1 (fr) 2009-07-06 2010-07-01 Cathéter et procédé de fabrication d'un tel cathéter

Country Status (2)

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SE (1) SE533762C2 (fr)
WO (1) WO2011005165A1 (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014078313A1 (fr) * 2012-11-13 2014-05-22 Boston Scientific Scimed, Inc. Implantation de nanoparticules dans des dispositifs médicaux
WO2016130713A1 (fr) 2015-02-10 2016-08-18 Cathprint Ab Dispositif médical à profil mince doté d'un circuit flexible intégré et et ses procédés de fabrication
US9456760B2 (en) 2013-03-14 2016-10-04 C. R. Bard, Inc. Closed catheter tip including electrically conductive pathway
US9474684B2 (en) 2012-03-20 2016-10-25 Chordate Medical Ab Electroactive vibration method
US20160338647A1 (en) * 2014-01-28 2016-11-24 St. Jude Medical, Cardiology Division, Inc. Catheter shaft with electrically-conductive traces
US9700224B2 (en) 2013-03-14 2017-07-11 C. R. Bard, Inc. Electrically conductive pathway in a closed-ended catheter
US9872814B2 (en) 2012-03-20 2018-01-23 Chordate Medical Ag Vibration pattern for vibration stimulation
US9925354B2 (en) 2012-10-24 2018-03-27 Evergreen Medical Technologies, Inc. Flex circuit ribbon based elongated members and attachments
US10178960B2 (en) 2013-02-11 2019-01-15 St. Jude Medical, Atrial Fibrillation Division, Inc. Printed electrode catheter
US10548671B2 (en) 2014-01-28 2020-02-04 St. Jude Medical International Holding S.á r.l. Medical device with a packaged electronic subassembly and method for fabricating the same
US11452484B2 (en) 2018-10-25 2022-09-27 Biosense Webster (Israel) Ltd. Electrodes on double-sided printed circuit board (PCB) to cancel far-held signal
US11596324B2 (en) 2018-10-25 2023-03-07 Biosense Webster (Israel) Ltd. Combined active current location (ACL) and tissue proximity indication (TPI) system
US11617542B2 (en) 2017-11-08 2023-04-04 Murata Manufacturing Co., Ltd. Electrical interconnection for a catheter

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3568660A (en) * 1967-11-20 1971-03-09 Battelle Development Corp Pacemaker catheter
US4762135A (en) * 1985-08-30 1988-08-09 Puije P D V D Cochlea implant
US5029585A (en) * 1989-07-14 1991-07-09 Baxter International Inc. Comformable intralumen electrodes
US5433742A (en) * 1993-11-19 1995-07-18 Willis; Allan Conductive adhesive band for cathether electrode
WO1998034446A1 (fr) * 1997-01-31 1998-08-06 Cuptronic Ab Nouveau procede de modification de surfaces
US6024702A (en) * 1997-09-03 2000-02-15 Pmt Corporation Implantable electrode manufactured with flexible printed circuit
US20050038320A1 (en) * 2003-08-15 2005-02-17 Hartwick Darrell J. Disposable endoscope
WO2007139479A1 (fr) * 2006-06-01 2007-12-06 Cathprint Ab cathÉter tubulaire pour utilisation invasive et procÉdÉ de fabrication de celui-ci

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3568660A (en) * 1967-11-20 1971-03-09 Battelle Development Corp Pacemaker catheter
US4762135A (en) * 1985-08-30 1988-08-09 Puije P D V D Cochlea implant
US5029585A (en) * 1989-07-14 1991-07-09 Baxter International Inc. Comformable intralumen electrodes
US5433742A (en) * 1993-11-19 1995-07-18 Willis; Allan Conductive adhesive band for cathether electrode
WO1998034446A1 (fr) * 1997-01-31 1998-08-06 Cuptronic Ab Nouveau procede de modification de surfaces
US6024702A (en) * 1997-09-03 2000-02-15 Pmt Corporation Implantable electrode manufactured with flexible printed circuit
US20050038320A1 (en) * 2003-08-15 2005-02-17 Hartwick Darrell J. Disposable endoscope
WO2007139479A1 (fr) * 2006-06-01 2007-12-06 Cathprint Ab cathÉter tubulaire pour utilisation invasive et procÉdÉ de fabrication de celui-ci

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9474684B2 (en) 2012-03-20 2016-10-25 Chordate Medical Ab Electroactive vibration method
US9872814B2 (en) 2012-03-20 2018-01-23 Chordate Medical Ag Vibration pattern for vibration stimulation
US9925354B2 (en) 2012-10-24 2018-03-27 Evergreen Medical Technologies, Inc. Flex circuit ribbon based elongated members and attachments
US10556089B2 (en) 2012-10-24 2020-02-11 Heraeus Medical Components Llc Flex circuit ribbon based elongated members and attachments
US9408951B2 (en) 2012-11-13 2016-08-09 Boston Scientific Scimed, Inc. Nanoparticle implantation in medical devices
WO2014078313A1 (fr) * 2012-11-13 2014-05-22 Boston Scientific Scimed, Inc. Implantation de nanoparticules dans des dispositifs médicaux
US10178960B2 (en) 2013-02-11 2019-01-15 St. Jude Medical, Atrial Fibrillation Division, Inc. Printed electrode catheter
US9700224B2 (en) 2013-03-14 2017-07-11 C. R. Bard, Inc. Electrically conductive pathway in a closed-ended catheter
US9456760B2 (en) 2013-03-14 2016-10-04 C. R. Bard, Inc. Closed catheter tip including electrically conductive pathway
US20160338647A1 (en) * 2014-01-28 2016-11-24 St. Jude Medical, Cardiology Division, Inc. Catheter shaft with electrically-conductive traces
US10548671B2 (en) 2014-01-28 2020-02-04 St. Jude Medical International Holding S.á r.l. Medical device with a packaged electronic subassembly and method for fabricating the same
US11116449B2 (en) 2014-01-28 2021-09-14 St. Jude Medical, Cardiology Division, Inc. Catheter shaft with electrically-conductive traces
EP3256201A4 (fr) * 2015-02-10 2018-10-24 Cathprint AB Dispositif médical à profil mince doté d'un circuit flexible intégré et et ses procédés de fabrication
WO2016130713A1 (fr) 2015-02-10 2016-08-18 Cathprint Ab Dispositif médical à profil mince doté d'un circuit flexible intégré et et ses procédés de fabrication
US11617542B2 (en) 2017-11-08 2023-04-04 Murata Manufacturing Co., Ltd. Electrical interconnection for a catheter
US11452484B2 (en) 2018-10-25 2022-09-27 Biosense Webster (Israel) Ltd. Electrodes on double-sided printed circuit board (PCB) to cancel far-held signal
US11596324B2 (en) 2018-10-25 2023-03-07 Biosense Webster (Israel) Ltd. Combined active current location (ACL) and tissue proximity indication (TPI) system

Also Published As

Publication number Publication date
SE0900936A1 (sv) 2010-12-28
SE533762C2 (sv) 2010-12-28

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