WO2011003412A3 - Longitudinale mischvorrichtung, insbesondere für die hochleistungsflüssigkeitschromatographie - Google Patents

Longitudinale mischvorrichtung, insbesondere für die hochleistungsflüssigkeitschromatographie Download PDF

Info

Publication number
WO2011003412A3
WO2011003412A3 PCT/DE2010/075058 DE2010075058W WO2011003412A3 WO 2011003412 A3 WO2011003412 A3 WO 2011003412A3 DE 2010075058 W DE2010075058 W DE 2010075058W WO 2011003412 A3 WO2011003412 A3 WO 2011003412A3
Authority
WO
WIPO (PCT)
Prior art keywords
flow
mixing
chamber area
high performance
guiding device
Prior art date
Application number
PCT/DE2010/075058
Other languages
English (en)
French (fr)
Other versions
WO2011003412A2 (de
Inventor
Joachim Wiechers
Peter Grohrock
Original Assignee
Dionex Softron Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dionex Softron Gmbh filed Critical Dionex Softron Gmbh
Publication of WO2011003412A2 publication Critical patent/WO2011003412A2/de
Publication of WO2011003412A3 publication Critical patent/WO2011003412A3/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/45—Mixing liquids with liquids; Emulsifying using flow mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4337—Mixers with a diverging-converging cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4522—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through porous bodies, e.g. flat plates, blocks or cylinders, which obstruct the whole diameter of the tube
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4524—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4524—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls
    • B01F25/45242—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls through a bed of fibres, steel wool or wood chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4524—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls
    • B01F25/45243—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through foam-like inserts or through a bed of loose bodies, e.g. balls through a foam or expanded material body

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)

Abstract

Die Erfindung betrifft eine Mischvorrichtung für das longitudinale Mischen einer aus wenigstens zwei Komponenten bestehenden Flüssigkeit, insbesondere für die Hochleistungsflϋssigkeitschromatographie, mit einem Eingangsport (11), welchem eine aus wenigstens zwei Komponenten bestehende Flüssigkeit zuführbar ist, mit einem Ausgangsport (15), von welchem die Flüssigkeit nach dem Durchströmen der Mischvorrichtung (10) abführbar ist, mit einer Mischkammer (14), die fluidisch mit dem Eingangsport (11) und dem Ausgangsport (15) verbunden ist, und mit einer in der Mischkammer (14) angeordneten Fritte (13), welche die Mischkammer (14) in einen mit dem Eingangsport (11) fluidisch verbundenen vorderen Kammerbereich (12) und einen mit dem Ausgangsport (15) fluidisch verbundenen hinteren Kammerbereich (18) unterteilt. Erfindungsgemäβ ist im vorderen Kammerbereich (12) oder im hinteren Kammerbereich (18) oder im vorderen und hinteren Kammerbereich (12, 18) eine Strömungsleitvorrichtung (17) vorgesehen. Die Strömungsleitvorrichtung (17) ist derart beschaffen, dass der Strömungswiderstand des vorderen oder hinteren Kammerbereichs (12, 18) mit der Strömungsleitvorrichtung (17) gross gegen den Strömungswiderstand des betreffenden vorderen oder hinteren Kammerbereichs ohne die Strömungsleitvorrichtung (17) und klein gegen den Strömungswiderstand der Fritte (13) ist.
PCT/DE2010/075058 2009-07-08 2010-07-08 Longitudinale mischvorrichtung, insbesondere für die hochleistungsflüssigkeitschromatographie WO2011003412A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009032394A DE102009032394B4 (de) 2009-07-08 2009-07-08 Verfahren zum longitudinalen Mischen einer aus wenigstens zwei flüssigen Komponenten bestehenden Flüssigkeit für die Hochleistungsflüssigkeitschromatographie
DE102009032394.5 2009-07-08

Publications (2)

Publication Number Publication Date
WO2011003412A2 WO2011003412A2 (de) 2011-01-13
WO2011003412A3 true WO2011003412A3 (de) 2011-04-28

Family

ID=43066732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2010/075058 WO2011003412A2 (de) 2009-07-08 2010-07-08 Longitudinale mischvorrichtung, insbesondere für die hochleistungsflüssigkeitschromatographie

Country Status (2)

Country Link
DE (1) DE102009032394B4 (de)
WO (1) WO2011003412A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11185830B2 (en) 2017-09-06 2021-11-30 Waters Technologies Corporation Fluid mixer
CN109959745A (zh) * 2017-12-22 2019-07-02 苏州普源精电科技有限公司 一种混合器及液相色谱仪
GB201817692D0 (en) * 2018-10-30 2018-12-19 Ge Healthcare Mixing device
DE102019117878A1 (de) 2019-07-02 2019-09-12 Dionex Softron Gmbh Gewebe in einem Chemiesystem, entsprechende Verwendung und Verfahren
CN114207433A (zh) 2019-08-12 2022-03-18 沃特世科技公司 用于色谱系统的混合器
EP4179310A1 (de) 2020-07-07 2023-05-17 Waters Technologies Corporation Mischer für die flüssigkeitschromatographie
EP4179311A1 (de) 2020-07-07 2023-05-17 Waters Technologies Corporation Kombinationsmischeranordnung zur rauschminderung in der flüssigkeitschromatographie
CN116194767A (zh) 2020-09-22 2023-05-30 沃特世科技公司 连续流混合器

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2060420A (en) * 1979-10-16 1981-05-07 Hamptonns Aercrete Ltd Improvements in or relating to the production of foam
GB2084887A (en) * 1980-10-07 1982-04-21 Bruker Analytische Messtechnik Mixing chamber
GB2318069A (en) * 1996-09-27 1998-04-15 Kevin Gary Platt Foam for use in the manufacture of an aerated concrete or polymer
US20070023454A1 (en) * 2005-07-25 2007-02-01 Heiner Ophardt Antibacterial foam generator
WO2007112892A2 (de) * 2006-03-29 2007-10-11 Carbotek Holding Gmbh Imprägnierer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0686848A1 (de) * 1994-05-09 1995-12-13 Shiseido Company Limited Flüssigchromatograph mit Mikro- oder Halbmikrokolonne
DE60008516T2 (de) 2000-07-20 2004-12-23 Agilent Technologies Inc., A Delaware Corp., Palo Alto Verfahren und Vorrichtung zum Mischen von Fluiden
JP3824160B2 (ja) 2002-08-28 2006-09-20 株式会社島津製作所 高速液体クロマトグラフ用混合装置
DE102006058026B4 (de) 2006-12-07 2009-12-24 Wissenschaftliche Gerätebau Dr.-Ing. Herbert Knauer GmbH HPLC-Anlage

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2060420A (en) * 1979-10-16 1981-05-07 Hamptonns Aercrete Ltd Improvements in or relating to the production of foam
GB2084887A (en) * 1980-10-07 1982-04-21 Bruker Analytische Messtechnik Mixing chamber
GB2318069A (en) * 1996-09-27 1998-04-15 Kevin Gary Platt Foam for use in the manufacture of an aerated concrete or polymer
US20070023454A1 (en) * 2005-07-25 2007-02-01 Heiner Ophardt Antibacterial foam generator
WO2007112892A2 (de) * 2006-03-29 2007-10-11 Carbotek Holding Gmbh Imprägnierer

Also Published As

Publication number Publication date
DE102009032394A1 (de) 2011-01-27
WO2011003412A2 (de) 2011-01-13
DE102009032394B4 (de) 2013-05-02

Similar Documents

Publication Publication Date Title
WO2011003412A3 (de) Longitudinale mischvorrichtung, insbesondere für die hochleistungsflüssigkeitschromatographie
MY153827A (en) Variable flow restrictor for use in a subterranean well
EP2392770A3 (de) System mit variablem Strömungswiderstand zur Verwendung in einem unterirdischen Bohrloch
BR112014030967A2 (pt) ejetor e método para operar um ejetor
WO2012033420A3 (en) Catheter and shunt system including the catheter
GB2479330B (en) A device for liquid treatment when compressing a well flow
WO2011045027A3 (de) Strömungskörper insbesondere für luftfahrzeuge
MX2013002308A (es) Series configuradas de restrictores de flujo variable para uso en un pozo subterraneo.
MY156507A (en) Alternating flow resistance increases and decreases for propagating pressure pulses in a subterranean well
WO2009137438A3 (en) Apparatus and methods for delivering therapeutic agents
GB2499147A (en) Microfluidic device with auxiliary and bypass channels
MX359727B (es) Entrada de espectrómetro de masas con flujo promedio reducido.
WO2007096049A3 (de) Dosiervorrichtung mit einer manuell betätigbaren pumpeinrichtung
WO2011057774A3 (en) Integrated choke manifold system for use in a well application
WO2007109333A3 (en) Apparatus and method for coating of elongate flimsy members
WO2012177977A3 (en) Flow compensator
WO2010017095A3 (en) Fluid preheater
MY172981A (en) Electrostatic coalescer and method for electrostatic coalescence
WO2014066036A3 (en) Hydroclone
BR112014026375A2 (pt) sistema de tratamento de descargas que possui um scr com uma entrada central
EP3118589A3 (de) Durchflusssensoranordnung mit umgehungskanal
PL2225483T3 (pl) Układ urządzeń do napełniania i filtrowania w korpusie zaworu
MY152671A (en) Urine meter
DE502004004910D1 (de) Durchflussmengenbegrenzer
WO2013140173A3 (en) Nozzle

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10752283

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 10752283

Country of ref document: EP

Kind code of ref document: A2