WO2010151074A3 - Conjugués contenant des photosensibilisateurs constitués de points quantiques et de dérivés de chlore et composition pour traiter et diagnostiquer un cancer contenant ces conjugués pour mettre en oeuvre une thérapie photodynamique - Google Patents
Conjugués contenant des photosensibilisateurs constitués de points quantiques et de dérivés de chlore et composition pour traiter et diagnostiquer un cancer contenant ces conjugués pour mettre en oeuvre une thérapie photodynamique Download PDFInfo
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- WO2010151074A3 WO2010151074A3 PCT/KR2010/004134 KR2010004134W WO2010151074A3 WO 2010151074 A3 WO2010151074 A3 WO 2010151074A3 KR 2010004134 W KR2010004134 W KR 2010004134W WO 2010151074 A3 WO2010151074 A3 WO 2010151074A3
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- WO
- WIPO (PCT)
- Prior art keywords
- treating
- composition
- diagnosing cancer
- quantum dot
- photodynamic therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
- A61K47/546—Porphyrines; Porphyrine with an expanded ring system, e.g. texaphyrine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Ceramic Engineering (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
La présente invention concerne des conjugués contenant des photosensibilisateurs constitués de points quantiques et de dérivés de chlore et une composition pour traiter et diagnostiquer un cancer contenant ces conjugués pour mettre en oeuvre une thérapie photodynamique. Les conjugués de la présente invention peuvent être utilisés en tant que médicament unique pour traiter et diagnostiquer un cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20090057910 | 2009-06-26 | ||
KR10-2009-0057910 | 2009-06-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010151074A2 WO2010151074A2 (fr) | 2010-12-29 |
WO2010151074A3 true WO2010151074A3 (fr) | 2011-05-19 |
Family
ID=43387066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2010/004134 WO2010151074A2 (fr) | 2009-06-26 | 2010-06-25 | Conjugués contenant des photosensibilisateurs constitués de points quantiques et de dérivés de chlore et composition pour traiter et diagnostiquer un cancer contenant ces conjugués pour mettre en oeuvre une thérapie photodynamique |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR101288460B1 (fr) |
WO (1) | WO2010151074A2 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2717920A4 (fr) * | 2011-06-11 | 2015-04-29 | Univ Central Florida Res Found | Nanosondes activables pour une administration intracellulaire de médicament |
KR101668561B1 (ko) | 2015-07-13 | 2016-10-21 | 원광대학교산학협력단 | 녹색형광단백질을 발현하는 유전자 및 로즈 벵갈을 이용한 암 질환의 광역학 치료용 조성물 및 이를 이용한 광역학 치료방법 |
US20170049891A1 (en) * | 2015-08-17 | 2017-02-23 | Nanoco Technologies Ltd. | 5-aminolevulinic acid conjugated quantum dot nanoparticle |
RU2638446C1 (ru) * | 2016-12-14 | 2017-12-13 | федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский ядерный университет МИФИ" (НИЯУ МИФИ) | Способ направленного разрушения раковых клеток |
KR101911725B1 (ko) | 2017-01-16 | 2018-12-28 | 주식회사 코어파마 | 적색형광단백질을 발현하는 유전자 및 틴 에틸 에티오푸르푸린을 이용한 광역학 치료용 조성물 및 이를 이용한 광역학 치료방법 |
CN107722075A (zh) * | 2017-10-09 | 2018-02-23 | 大连理工大学 | 一类二氢卟吩葡萄糖苷类化合物及其制备方法与应用 |
KR102277244B1 (ko) * | 2019-09-03 | 2021-07-13 | 인제대학교 산학협력단 | 생체 영상화 및 광열치료용 탄소양자점-폴리피롤 나노 복합체 및 이의 제조방법 |
KR102256817B1 (ko) | 2019-09-09 | 2021-05-26 | 한국교통대학교산학협력단 | 자가 치유 전기화학적 무선진단이 가능한 탄소양자점 기반 수화젤의 제조방법 및 이를 활용한 자기 치유 전기화학적 무선진단방법 |
KR102294374B1 (ko) | 2019-09-09 | 2021-08-26 | 한국교통대학교산학협력단 | 전기화학적 무선 진단이 가능한 탄소 양자점의 제조방법, 및 이를 활용한 전기화학적 무선진단방법 |
CN114933904B (zh) * | 2022-06-14 | 2024-02-06 | 中国医科大学 | 一种用于光学诊疗的超薄壳层手性硒化镉/硫化镉材料及其制备方法与应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20080104495A (ko) * | 2007-05-28 | 2008-12-03 | 전남대학교산학협력단 | 양자점을 이용한 생물학적 검출키트 및 방법 |
-
2010
- 2010-06-25 KR KR1020100060373A patent/KR101288460B1/ko not_active IP Right Cessation
- 2010-06-25 WO PCT/KR2010/004134 patent/WO2010151074A2/fr active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20080104495A (ko) * | 2007-05-28 | 2008-12-03 | 전남대학교산학협력단 | 양자점을 이용한 생물학적 검출키트 및 방법 |
Non-Patent Citations (4)
Title |
---|
BECHET, DENISE ET AL.: "Nanoparticles as vehicles for delivery of photodynamic therapy agents", TRENDS IN BIOTECHNOLOGY, vol. 26, no. 11, 2008, pages 612 - 621 * |
CHO, SUNG JU ET AL.: "Long-Term Exposure to CdTe Quantum Dots Causes Functional Impairments in Live Cells", LANGMUIR, vol. 23, 2007, pages 1974 - 1980 * |
SHAN, YAMING ET AL.: "NHS-mediated QDs-peptide/protein conjugation and its application for cell labeling", TALANTA, vol. 75, 2008, pages 1008 - 1014, XP022624863, DOI: doi:10.1016/j.talanta.2007.12.040 * |
TSAY, M. JAMES ET AL.: "Singlet Oxygen Production by Peptide-Coated Quantum Dot- Photosensitizer Conjugates.", J. AM. CHEM. SOC., vol. 129, 2007, pages 6865 - 6871 * |
Also Published As
Publication number | Publication date |
---|---|
KR101288460B1 (ko) | 2013-07-26 |
WO2010151074A2 (fr) | 2010-12-29 |
KR20110000524A (ko) | 2011-01-03 |
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