WO2010146313A4 - Use of a composition comprising mother-of-pearl and optionally active substances of cocos nucifera as a nutritive medium that can dilute reproductive cells - Google Patents

Use of a composition comprising mother-of-pearl and optionally active substances of cocos nucifera as a nutritive medium that can dilute reproductive cells Download PDF

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Publication number
WO2010146313A4
WO2010146313A4 PCT/FR2010/051206 FR2010051206W WO2010146313A4 WO 2010146313 A4 WO2010146313 A4 WO 2010146313A4 FR 2010051206 W FR2010051206 W FR 2010051206W WO 2010146313 A4 WO2010146313 A4 WO 2010146313A4
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pearl
mother
composition
nutrient medium
group
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PCT/FR2010/051206
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French (fr)
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WO2010146313A3 (en
WO2010146313A2 (en
Inventor
Georges Camprasse
Serge Camprasse
Joël Drai
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Jd Invest
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Publication of WO2010146313A3 publication Critical patent/WO2010146313A3/en
Publication of WO2010146313A4 publication Critical patent/WO2010146313A4/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/061Sperm cells, spermatogonia
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/76Undefined extracts from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/80Undefined extracts from animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Medical Informatics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Developmental Biology & Embryology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)

Abstract

The invention relates to the use of a composition comprising clamshell mother-of-pearl, and optionally active substances of the water of Cocos nucifera as a nutritive medium that can dilute reproductive cells.

Claims

REVENDICATIONS MODIFIEES reçues par le Bureau international le 21 avril 2011 (21.04.2011) AMENDED CLAIMS received by the International Bureau on April 21, 2011 (21.04.2011)
1. Utilisation d'une composition comprenant de la nacre de coquilles de bivalves, et éventuellement, des principes actifs de l'eau de Cocos nucifera comme milieu nutritif dilueur de cellules reproductrices. 1. Use of a composition comprising mother-of-pearl of bivalve shells, and optionally, active ingredients of Cocos water nucifera as diluent nutrient medium of reproductive cells.
2. Utilisation selon la revendication 1, caractérisée par le fait que la nacre est issue de coquille de bivalves choisis dans le groupe comprenant la Pinctada Maxima, la Pinctada Margaritifera ou autres Pinctadines, le Tridacnae Gigas, et leurs mélanges.  2. Use according to claim 1, characterized in that the nacre is derived from shell bivalves selected from the group consisting of Pinctada Maxima, Pinctada Margaritifera or other Pinctadines, Tridacnae Gigas, and mixtures thereof.
3. Utilisation selon l'une des revendications 1 ou 2, caractérisée par le fait que la nacre est choisie dans le groupe comprenant de la nacre micronisée, de la nanonacre, de la nacre mécanostructurée, et leurs mélanges.  3. Use according to one of claims 1 or 2, characterized in that the nacre is selected from the group comprising micronized mother-of-pearl, nanonacre, nacre mechanostructured, and mixtures thereof.
4. Utilisation selon l'une des revendications 1 à 3, caractérisé par le fait que les principes actifs de Cocos nucifera sont constitués par l'eau prélevée stérilement de la noix Cocos nucifera mature de 6 mois.  4. Use according to one of claims 1 to 3, characterized in that the active ingredients of Cocos nucifera are constituted by water sterilely removed from the walnut Cocos nucifera mature 6 months.
5. Utilisation selon l'une quelconque des revendications 1 à 4, caractérisé en ce que les principes actifs sont extraits de l'eau de Cocos nucifera obtenus par un procédé comprenant les étapes suivantes : filtration frontale clarifiante, super centrifugation, ultra filtration tangentielle, concentration et lyophilisation.  5. Use according to any one of claims 1 to 4, characterized in that the active ingredients are extracted from the water of Cocos nucifera obtained by a process comprising the following steps: clarifying frontal filtration, super centrifugation, ultra-tangential filtration, concentration and lyophilization.
6. Utilisation selon l'une quelconque des revendications 1 à 5, caractérisé en ce que ladite composition comprend au moins un antibiotique, de préférence choisi dans le groupe comprenant la pénicilline, la gentamycine, la streptomycine, et leurs mélanges.  6. Use according to any one of claims 1 to 5, characterized in that said composition comprises at least one antibiotic, preferably selected from the group comprising penicillin, gentamycin, streptomycin, and mixtures thereof.
7. Utilisation selon l'une quelconque des revendications 1 à 6, caractérisé en ce que ladite composition comprend de l'EDTA, du glucose, de l'acide citrique. 7. Use according to any one of claims 1 to 6, characterized in that said composition comprises EDTA, glucose, citric acid.
8. Milieu nutritif dilueur de cellules reproductrices comprenant :  8. Reproductive cell diluent nutrient medium comprising:
- de la nacre de coquilles de bivalves se trouvant au moins partiellement sous la forme choisie dans le groupe consistant en la nacre nanonisée, la nacre nanostructurée ou leurs mélanges,  mother-of-pearl of bivalve shells at least partially in the form chosen from the group consisting of nano-sized mother-of-pearl, nanostructured mother-of-pearl or their mixtures,
- et éventuellement, des principes actifs de l'eau de Cocos nucifera;  - and possibly, active ingredients of coconut water nucifera;
caractérisé par le fait que la nacre est issue de coquille de bivalves choisis dans le groupe comprenant la Pinctada Maxima, la Pinctada Margaritifera ou autres Pinctadines, le Tridacnae Gigas, et leurs mélanges. characterized in that the nacre is derived from bivalve shell selected from the group consisting of Pinctada Maxima, Pinctada Margaritifera or other Pinctadines, Tridacnae Gigas, and mixtures thereof.
9. Milieu nutritif selon la revendication 8, caractérisé par le fait que les principes actifs de Cocos nucifera sont constitués par l'eau prélevée stérilement de la noix Cocos nucifera mature de 6 mois.  9. Nutrient medium according to claim 8, characterized in that the active ingredients of Cocos nucifera are constituted by the water sampled sterile nut Cocos nucifera mature 6 months.
10. Milieu nutritif selon l'une des revendications 8 ou 9, caractérisé en ce que les principes actifs sont extraits de l'eau de Cocos nucifera obtenus par un procédé comprenant les étapes suivantes : filtration frontale clarifiante, super centrifugation, ultra filtration tangentielle, concentration et lyophilisation.  10. Nutrient medium according to one of claims 8 or 9, characterized in that the active ingredients are extracted from the water of Cocos nucifera obtained by a process comprising the following steps: clarifying frontal filtration, super centrifugation, ultra-tangential filtration, concentration and lyophilization.
11. Milieu nutritif selon l'une quelconque des revendications 8 à 10, caractérisé en ce qu'il comprend au moins un antibiotique, de préférence choisi dans le groupe comprenant la pénicilline, la gentamycine, la streptomycine, et leurs mélanges.  11. Nutrient medium according to any one of claims 8 to 10, characterized in that it comprises at least one antibiotic, preferably selected from the group comprising penicillin, gentamycin, streptomycin, and mixtures thereof.
12. Milieu nutritif selon l'une quelconque des revendications 8 à 11, caractérisé en ce qu'il comprend de l'EDTA, du glucose, de l'acide citrique. 25 12. Nutrient medium according to any one of claims 8 to 11, characterized in that it comprises EDTA, glucose, citric acid. 25
13. Composition pour insémination comprenant le milieu nutritif dilueur défini dans l'une quelconque des revendications 8 à 12 ou la composition utilisée selon l'une des revendications 1 à 7, et des cellules reproductrices de mammifères non humains, de préférence choisies dans le groupe comprenant les spermatozoïdes, un ovocyte, une pièce ovarienne. 13. Composition for insemination comprising the diluent nutrient medium defined in any one of claims 8 to 12 or the composition used according to one of claims 1 to 7, and reproductive cells of non-human mammals, preferably chosen from the group including spermatozoa, an oocyte, an ovarian piece.
14. Composition selon la revendication 13, caractérisée en ce qu'elle est réfrigérée ou congelée.  14. The composition of claim 13, characterized in that it is chilled or frozen.
PCT/FR2010/051206 2009-06-17 2010-06-16 Use of a composition comprising mother-of-pearl and optionally active substances of cocos nucifera as a nutritive medium that can dilute reproductive cells WO2010146313A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0954085 2009-06-17
FR0954085A FR2946885B1 (en) 2009-06-17 2009-06-17 NACRE COMPOSITION FOR CORRECTING NAMING FAULTS IN MAMMALS.
FR0957298A FR2946837B1 (en) 2009-06-17 2009-10-16 NUTRIENT MEDIUM DILUTIVE OF REPRODUCTIVE CELLS COMPRISING NACRE AND POSSIBLY ACTIVE INGREDIENTS OF COCOS NUCIFERA
FR0957298 2009-10-16

Publications (3)

Publication Number Publication Date
WO2010146313A2 WO2010146313A2 (en) 2010-12-23
WO2010146313A3 WO2010146313A3 (en) 2011-04-14
WO2010146313A4 true WO2010146313A4 (en) 2011-06-09

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ID=41600787

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/FR2010/051203 WO2010146310A1 (en) 2009-06-17 2010-06-16 Mother-of-pearl composition for correcting implantation problems in mammals
PCT/FR2010/051206 WO2010146313A2 (en) 2009-06-17 2010-06-16 Use of a composition comprising mother-of-pearl and optionally active substances of cocos nucifera as a nutritive medium that can dilute reproductive cells

Family Applications Before (1)

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PCT/FR2010/051203 WO2010146310A1 (en) 2009-06-17 2010-06-16 Mother-of-pearl composition for correcting implantation problems in mammals

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WO (2) WO2010146310A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784091A (en) * 2015-03-30 2015-07-22 陈宏乔 Deep sea giant clam facial cleanser, deep sea giant clam hydrating mask essence and preparation methods thereof
CN106577413B (en) * 2016-11-01 2019-07-12 海南大学 A kind of artificial induction's oviposition method of giant clam

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
FR954066A (en) 1947-09-26 1949-12-19 Improvements to machines for manufacturing twisted-core tracks
FR2742661B1 (en) * 1995-12-21 1998-07-10 Texinfine Sa NEW USE OF NACRE-CONTAINING COMPOSITIONS
FR2759909B1 (en) 1997-02-25 1999-04-30 Agronomique Inst Nat Rech SEMEN DILUTER COMPRISING NATIVE PHOSPHOCASEINATE OR BETA-[LACTOGLOBULIN, METHOD FOR PREPARING IT AND USES THEREOF
FR2793495B1 (en) 1999-05-14 2001-08-10 Imv Technologies THINNER FOR CRYOPRESERVATION OF CATTLE SPERMATOZOIDS
FR2799125B1 (en) * 1999-10-05 2002-01-18 Centre Nat Rech Scient PROCESS FOR THE PREPARATION OF A COMPOSITION BY EXTRACTION OF NACRE, COMPRISING THE COMPLETE COMPONENTS OF THE NACRE, COMPOSITION OBTAINED BY THIS PROCESS AND ITS USE IN PHARMACY AND COSMETICS.
FR2808657B1 (en) * 2000-05-11 2003-06-13 Pharma Futura EDIBLE COMPOSITION COMPRISING MICRONIZED NACRE POWDER
SE0003260D0 (en) * 2000-09-14 2000-09-14 Anders Uhlin New use of hyaluronan
FR2827478B1 (en) * 2001-07-18 2003-10-24 Jean Louis Montero PROCESS FOR THE PREPARATION OF A NACRE-BASED POWDER, ISOLATED PROTEIN FROM SAID POWDER AND THEIR USES IN BONE SURGERY AND IN VARIOUS OSTEOARTICULAR PATHOLOGIES
EP1391152A1 (en) 2002-08-19 2004-02-25 Stoeterij Zangersheide N.V. Thinner for conservation of fresh and frozen sperm
CN101143175A (en) * 2006-09-15 2008-03-19 丛繁滋 New jinji preparation for treating male and female pelvic inflammation and production method thereof
BRPI0700624A (en) * 2007-02-28 2008-10-14 Pedrazzi Cesar Augusto Ferraz semen manipulation process
CN101199771A (en) * 2007-12-21 2008-06-18 北京中科雍和医药技术有限公司 Medicament compound for treating menopause syndrome and preparing method thereo

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Publication number Publication date
WO2010146310A1 (en) 2010-12-23
FR2946837B1 (en) 2013-11-01
WO2010146313A3 (en) 2011-04-14
FR2946885B1 (en) 2011-08-26
WO2010146313A2 (en) 2010-12-23
FR2946837A1 (en) 2010-12-24
FR2946885A1 (en) 2010-12-24

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