WO2010134481A1 - Dispositif d'affichage d'image médicale et procédé d'affichage d'image médicale - Google Patents

Dispositif d'affichage d'image médicale et procédé d'affichage d'image médicale Download PDF

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Publication number
WO2010134481A1
WO2010134481A1 PCT/JP2010/058265 JP2010058265W WO2010134481A1 WO 2010134481 A1 WO2010134481 A1 WO 2010134481A1 JP 2010058265 W JP2010058265 W JP 2010058265W WO 2010134481 A1 WO2010134481 A1 WO 2010134481A1
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Prior art keywords
projection
pixel
medical image
image display
image
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PCT/JP2010/058265
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English (en)
Japanese (ja)
Inventor
良洋 後藤
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株式会社 日立メディコ
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Priority to CN201080020112.3A priority Critical patent/CN102421367B/zh
Priority to JP2011514396A priority patent/JP5701208B2/ja
Publication of WO2010134481A1 publication Critical patent/WO2010134481A1/fr

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    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T15/00—3D [Three Dimensional] image rendering
    • G06T15/08—Volume rendering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/46—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with special arrangements for interfacing with the operator or the patient
    • A61B6/461—Displaying means of special interest
    • A61B6/463—Displaying means of special interest characterised by displaying multiple images or images and diagnostic data on one display
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/032—Transmission computed tomography [CT]

Definitions

  • the present invention relates to a medical image display apparatus and a medical image display method for displaying a medical image obtained from a medical image diagnostic apparatus including an X-ray CT apparatus, an MRI apparatus, and an ultrasonic apparatus, and retains a pixel value acquired at the time of imaging.
  • the present invention also relates to a technique for displaying a projection image having depth information.
  • One of the three-dimensional image display methods for displaying a medical image obtained from a medical image diagnostic apparatus including an X-ray CT apparatus, an MRI apparatus, and an ultrasonic apparatus is a maximum value projection (MIP) method.
  • the maximum value projection method is a method in which projection processing in an arbitrary direction is performed on 3D image data, and the maximum pixel value on the projection line is displayed on the projection plane.
  • the image obtained by this method is an MIP image and be called.
  • the MIP image holds a pixel value acquired at the time of shooting, for example, a CT value in the case of a CT image, but does not have depth information, so there is no perspective with the MIP image as it is.
  • Patent Document 1 There is a method disclosed in Patent Document 1 as a method for obtaining a perspective MIP image.
  • each of the three-dimensional image data is weighted with a plurality of weighting functions, and the maximum value projection processing is performed on the plurality of weighted three-dimensional image data. The maximum value projection results are added up.
  • Patent Document 1 after the three-dimensional image data is weighted, a plurality of projection images obtained by performing the maximum value projection process on the weighted three-dimensional image data are added, so that finally obtained The obtained image does not hold a pixel value acquired at the time of imaging, for example, a CT value, and it is difficult for an interpreting doctor to make a diagnosis based on the CT value.
  • the CT value which is a pixel value acquired at the time of imaging
  • the density value which is a pixel value acquired at the time of imaging
  • the CT value is extremely important information for knowing what state the part in the subject is.
  • the density value which is a pixel value acquired at the time of imaging, is also important information for diagnosis, like the CT value.
  • an object of the present invention is to provide a medical image display apparatus and a medical image display method for creating and displaying a projection image having depth information while retaining a pixel value acquired at the time of photographing.
  • the present invention provides a projection image creation unit that creates a projection image by projecting a medical image obtained from a medical image diagnostic apparatus onto a projection surface, and a projection image display unit that displays the projection image.
  • a projected image creating unit that extracts a pixel having a pixel value satisfying a predetermined threshold condition from pixels on a projection line; and When the pixel extraction unit cannot extract a pixel having a pixel value satisfying the threshold condition, an arbitrary pixel on the projection line is selected as a projection pixel, and the pixel value satisfies the threshold condition
  • a projection pixel selection unit that selects a projection pixel from pixels on the projection line based on a distance from the projection plane when a pixel can be extracted, and the selected projection image is displayed on the projection plane Project to And features.
  • the present invention also provides a projection image creation step of creating a projection image by projecting a medical image obtained from the medical image diagnostic apparatus onto a projection plane, and a projection image display step of displaying the projection image.
  • the projection image creation step includes: a pixel extraction step of extracting a pixel having a pixel value satisfying a predetermined threshold condition from pixels on the projection line; and the pixel extraction step When a pixel having a pixel value satisfying the threshold condition cannot be extracted, an arbitrary pixel on the projection line is selected as a projection pixel, and a pixel having a pixel value satisfying the threshold condition can be extracted
  • a projection pixel selection step of selecting a projection pixel from pixels on the projection line based on a distance from the projection plane, and projecting the selected projection image Characterized in that it projected on.
  • a medical image display device and a medical image display method for creating and displaying a projection image having depth information while retaining pixel values acquired at the time of photographing.
  • the figure which shows the hardware constitutions of the medical image display apparatus of this invention The figure which shows the flow of a process of Example 1 of this invention.
  • the figure which shows an example of GUI for setting a threshold value and distance by this invention Diagram for explaining how to create a projected image
  • the figure explaining the method of determining a projection pixel by this invention Comparison diagram of projection image created by the present invention and conventional MIP image
  • the figure explaining that the projection image created by the present invention is shaded
  • a figure that supplementarily explains how to obtain the distance between two points specified on a projected image The figure which shows an example of GUI for displaying the pixel value profile on a projection line
  • FIG. 1 is a diagram showing a hardware configuration of the medical image display apparatus 1.
  • the medical image display device 1 has a CPU (Central Processing Unit) 2, a main memory 3, a storage device 4, a display memory 5, a display device 6, a controller 7 connected to a mouse 8, a keyboard 9, and a network adapter 10, and a system bus 11 is configured so as to be able to send and receive signals.
  • the medical image display device 1 is connected to a medical image photographing device 13 and a medical image database 14 via a network 12 so as to be able to send and receive signals.
  • “to enable signal transmission / reception” indicates a state in which signals can be transmitted / received to each other or from one to the other, regardless of whether they are electrically or optically wired or wireless.
  • the CPU2 is a device that controls the operation of each component.
  • the CPU 2 loads a program stored in the storage device 4 and data necessary for program execution into the main memory 3 and executes it.
  • the storage device 4 is a device that stores medical image information captured by the medical image capturing device 13, and is specifically a hard disk or the like.
  • the storage device 4 may be a device that exchanges data with a portable recording medium such as a flexible disk, an optical (magnetic) disk, a ZIP memory, or a USB memory.
  • the medical image information is acquired from the medical image photographing device 13 and the medical image database 14 via a network 12 such as a LAN (Local Area Network).
  • the storage device 4 stores a program executed by the CPU 2 and data necessary for program execution.
  • the main memory 3 stores programs executed by the CPU 2 and the progress of arithmetic processing.
  • the display memory 5 temporarily stores display data to be displayed on the display device 6 such as a liquid crystal display or a CRT (Cathode Ray Tube).
  • the mouse 8 and the keyboard 9 are operation devices for an operator to give an operation instruction to the medical image display device 1.
  • the mouse 8 may be another pointing device such as a trackpad or a trackball.
  • the controller 7 detects the state of the mouse 8, acquires the position of the mouse pointer on the display device 6, and outputs the acquired position information and the like to the CPU 2.
  • the network adapter 10 is for connecting the medical image display apparatus 1 to a network 12 such as a LAN, a telephone line, or the Internet.
  • the medical image photographing device 13 is a device that acquires medical image information such as a tomographic image of a subject.
  • the medical imaging apparatus 13 is, for example, an MRI apparatus, an X-ray CT apparatus, an ultrasonic diagnostic apparatus, a scintillation camera apparatus, a PET apparatus, a SPECT apparatus, or the like.
  • the medical image database 14 is a database system that stores medical image information captured by the medical image capturing device 13.
  • FIG. 2 is a diagram showing a processing flow of the first embodiment of the present invention. Hereinafter, each step of FIG. 2 will be described in detail.
  • a CT image is used as a medical image.
  • an MR image, an ultrasonic image, or the like may be used.
  • Step S201 The CPU 2 acquires the three-dimensional image data of the subject selected by the operator by operating the mouse 8 or the keyboard 9 from the medical image photographing device 13 or the medical image database 14 via the network 12.
  • the three-dimensional image data is several to hundreds of tomographic images obtained by imaging a subject, and is configured to be continuously arranged in a certain direction, for example, a direction perpendicular to the tomographic plane. is there.
  • the CPU 2 acquires projection line and projection plane data set by the operator operating the mouse 8 and the keyboard 9.
  • the projection line data is a projection direction or the like with respect to the three-dimensional image data
  • the projection plane data is a relative position with respect to the three-dimensional image data.
  • Step S202 The CPU 2 determines whether or not there is a pixel having a pixel value larger than a predetermined threshold on the projection line. If a pixel having a pixel value larger than the threshold is on the projection line, the process proceeds to S203, and if not, the process proceeds to S205.
  • a threshold value stored in advance in the storage device 4 may be used, or the operator can use a pointing device such as the mouse 8 from the screen 600 as shown in FIG.
  • a set threshold value may be used.
  • FIG. 3 will be described in detail later. For example, when it is desired to observe a region having a CT value of about 400, the operator sets the threshold value to 400.
  • the “pixel value larger than the threshold value” here is the same as the “pixel value that is equal to or greater than the threshold value” or “the pixel value that satisfies the threshold value”. There is no impact on the device or system to be applied.
  • Step S203 The CPU 2 stores the coordinates of the pixel closest to the projection plane in the main memory 3 among the pixels having a pixel value larger than the threshold value.
  • a method of determining the coordinates of the pixel closest to the projection plane among the pixels having a pixel value larger than the threshold value will be described with reference to FIGS. In the following description, it is assumed that a value substantially equal to the pixel values A2 and B2 is set as the threshold value.
  • FIG. 4 is a diagram illustrating a state in which the three-dimensional image 400 is projected onto the projection plane 410 using the projection lines 411A and 411B.
  • the three-dimensional image 400 includes a spine 401, a rib, and a blood vessel 402.
  • the pixel value A1 of the spine 401 and the pixel value B1 of the ribs are larger than the pixel values A2 and B2 of the blood vessel 402.
  • the projection lines 411A and 411B are orthogonal to the projection plane 401.
  • the projection plane 401 is a plane composed of the H axis and the V axis, and the direction orthogonal to the projection plane 401 is the P axis.
  • the projection lines 411A and 411B are parallel to the P axis. Further, the projection line 411A is a line passing through the spine 401 having the pixel value A1 and the blood vessel 402 having the pixel value A2, and the projection line 411B is a line passing through the blood vessel 402 having the pixel value B2 and the rib having the pixel value B1. It is.
  • FIG. 5 shows CT value profiles on the projection lines 411A and 411B, with the vertical axis representing the CT value and the horizontal axis representing the distance from the projection plane.
  • Fig. 5 (a) shows the CT value profile over almost the entire area of the projection lines 411A and 411B shown in Fig. 4, and
  • Fig. 5 (b) shows a part of the P-axis direction of Fig. 5 (a). It is an enlarged view. Since the projection line 411A passes through the spine 401 and the blood vessel 402, the CT value profile on the projection line 411A becomes a curve as shown by the broken line in FIG.
  • the CT value profile on the projection line 411B is a curve as shown by the solid line in FIG. 5 (a). Comparing the profile on the projection line 411A and the profile on the projection line 411B with the threshold value, and searching for the coordinates of the P axis of the pixel closest to the projection plane among the pixels having pixel values larger than the threshold value , P A and P B respectively. Note that the coordinates of the H axis and the V axis are determined for each projection line because the projection line is orthogonal to the projection plane. Therefore, (H A , V A , P A ) and (H B , V B , P B ) are determined as the coordinates (H, V, P) stored in this step.
  • Step S204 The CPU 2 projects the pixel value of the pixel at the coordinate obtained by shifting the predetermined distance ⁇ P on the projection line from the coordinate stored in S203 on the projection plane.
  • the value of the distance ⁇ P may be positive or negative. If the value of the distance ⁇ P is positive, the pixel value of the coordinate shifted in the direction away from the projection plane is projected, and if it is negative, the value approaches the projection plane. Will shift in the direction.
  • the operator may set the distance ⁇ P from the screen 600 as shown in FIG. 3 using a pointing device such as the mouse 8.
  • FIG. 3 will be described in detail later.
  • the coordinates stored in S203 are (H A , V A , P A ) and (H B , V B , P B )
  • the coordinates obtained by shifting the distance ⁇ P on the projection line are (H A , V A , P A + ⁇ P) and (H B , V B , P B + ⁇ P)
  • the pixel values of the respective coordinates are obtained on the profile shown in FIG. 5B, and are A2 ′ and B1 ′.
  • the CPU 2 projects the obtained pixel values A2 ′ and B1 ′ onto the projection plane 401 as shown in FIG.
  • the pixel value A2 ′ is different from the pixel value A2, and the pixel value B1 ′ is also different from the pixel value B1.
  • the profile on the projection line is different in different parts, so the projected pixel values are different values, for example, A2 'and B1', and the difference in parts is on the projected image. Will be reflected.
  • Step S205 The CPU 2 projects the pixel value of any pixel on the projection line onto the projection plane.
  • the pixel value projected in this step may be the maximum pixel value or the minimum pixel value on the projection line. Further, an existing projection method such as calculating and projecting an average value of all pixel values on the projection line may be used.
  • Step S206 The CPU 2 determines whether or not all projection lines are projected on the projection plane. If all projection lines are projected, the process proceeds to S208, and if there is a projection line that is not projected, the process proceeds to S207.
  • Step S207 The CPU 2 moves the projection line to the next projection line not projected on the projection plane, and then returns to S202.
  • Step S208 The CPU 2 displays the projection image on the display device 6.
  • a projection image according to the present embodiment is created and displayed on a screen 600 as shown in FIG. 3, for example.
  • the screen 600 shown in FIG. 3 will be described.
  • FIG. 3 shows an example of a screen 600 displayed on the display device 6.
  • the screen 600 includes a projected image display area 601, a threshold setting bar 602, and a distance setting bar 603.
  • the projected image display area 601 is an area where the projected image created by the present embodiment is displayed.
  • the threshold setting bar 602 is an operation icon for setting the threshold used in S202.
  • the operator can change the threshold value by operating the threshold setting bar 602 using a pointing device such as the mouse 8.
  • the threshold value setting bar 602 shown here can set a threshold value in the range of -1000 to 2000.
  • the distance setting bar 603 is an operation icon for setting the distance ⁇ P used in S204.
  • the operator can change the distance by operating the distance setting bar 603 using a pointing device such as the mouse 8.
  • the distance value can be set in the range of -2 mm to 2 mm.
  • the unit of distance is mm, but the unit of distance may be the number of pixels.
  • Fig. 6 (a) shows an example of the projection image created by this embodiment in comparison with the MIP image shown in Fig. 6 (b).
  • Fig. 6 shows the projection image and MIP image of this example using 3D image data in which blood vessels running parallel to the body axis of the subject are simulated in the chest rib image data. is there.
  • the MIP image shown in FIG. 6 (b) all the ribs appear to be located in front of the blood vessels, whereas in the projection image created by the present embodiment shown in FIG. The positional relationship with the blood vessel in the depth direction is correctly displayed.
  • all of the ribs are displayed with substantially the same pixel value, whereas in the projection image created according to the present embodiment, the ribs are displayed as shaded.
  • FIG. 7 is a diagram showing a state in which a part 700 such as a rib is projected by a projection line group 710.
  • the pixel value at the boundary portion of the part 700 is smaller than the internal pixel value. Therefore, when an equal pixel value line is drawn in the part 700, the pixel value becomes 701 to 703, and the equal pixel value line 703 ⁇ equal pixel.
  • value line 702 ⁇ equal pixel value line 701 is established.
  • the maximum pixel value on the projection line is projected in the MIP image, so that the profile 721 indicated by the solid line is obtained.
  • the pixel value on the broken line 711 which is the coordinate shifted by the distance ⁇ P from the boundary of the part 700 is projected, so that the profile 722 indicated by the broken line is obtained.
  • the projected image according to the present embodiment is displayed as shaded, and becomes an image having depth information while retaining the pixel value acquired at the time of photographing.
  • FIG. 9 shows an example of a GUI displayed on the display device 6 in order to display the pixel value profile on the projection line.
  • the screen 600 includes a cursor 801, a projection image display area 601, a profile button 604, and an end button 605.
  • the cursor 801 is used by the operator to designate an arbitrary position on the screen 600 by operating a pointing device such as the mouse 8.
  • a profile button 604 is used to display a CT value profile on a projection line passing through a specified position.
  • An end button 605 is used to end the profile display.
  • a CT value profile passing through the designated position as shown in FIG. 9 is displayed.
  • the operator can continuously observe the CT values in the direction orthogonal to the projection plane at the point designated by the cursor 801. As a result, the diagnosis based on the CT value can be performed in more detail for the site to be observed.
  • Example 1 was to create a projection image with a single value of the distance ⁇ P.
  • different projection images are created using a plurality of distances ⁇ P, and the created projection images are sequentially displayed.
  • the operator can continuously observe the CT value in the direction orthogonal to the projection plane, so that the diagnosis based on the CT value can be performed in more detail.
  • FIG. 10 is a diagram showing a processing flow of the second embodiment of the present invention. Hereinafter, each step of FIG. 10 will be described in detail. The same steps as those in the first embodiment are denoted by the same step symbols, and the description thereof is omitted.
  • Step S1008 The CPU 2 stores the created projection image in association with the distance ⁇ P.
  • Step S1009 The CPU 2 determines whether a projection image is stored for each of a plurality of predetermined ⁇ P. If projection images are stored for all ⁇ P, the process proceeds to S1011, and if not, the process proceeds to S1010.
  • Step S1010 After changing the value of the distance ⁇ P, the CPU 2 returns to S202.
  • Step S1011 The CPU 2 causes the display device 6 to continuously display the plurality of projection images stored in S1008 according to the value of ⁇ P. Or you may display the projection image corresponding to (DELTA) P according to (DELTA) P input via GUI with which an operator can change (DELTA) P arbitrarily.
  • a plurality of projection images created according to the present embodiment are sequentially displayed.
  • the operator can set the observation target region on the projection plane by appropriately setting the threshold value of the observation target region.
  • the CT values in the orthogonal direction can be observed continuously. As a result, the diagnosis based on the CT value can be performed in more detail for the site to be observed.
  • the coordinates of the pixel farthest from the projection plane may be stored instead of the coordinates of the pixel closest to the projection plane among the pixels having a pixel value larger than the threshold value. Saving the coordinates of pixels far from the projection plane is equivalent to arranging the projection plane on the opposite side.
  • 1 medical image display device 2 CPU, 3 main memory, 4 storage device, 5 display memory, 6 display device, 7 controller, 8 mouse, 9 keyboard, 10 network adapter, 11 system bus, 12 network, 13 medical imaging device , 14 Medical image database

Abstract

L'invention porte sur un dispositif d'affichage d'image médicale pour créer/afficher une image de projection ayant, également, des informations de profondeur tout en conservant les valeurs de pixel acquises lorsque l'image a été capturée. Le dispositif d'affichage d'image médicale pour créer et afficher une image de projection par projection d'une image médicale acquise à partir d'un dispositif de diagnostic à image médicale sur une surface de projection est caractérisé en ce que ledit dispositif est pourvu d'une unité d'extraction de pixel pour extraire un pixel ayant une valeur de pixel satisfaisant une condition de seuil prédéterminée, parmi les pixels sur une ligne de projection, et d'une unité de sélection de pixel de projection pour sélectionner un pixel donné sur la ligne de projection en tant que pixel de projection, si l'unité d'extraction de pixel n'a pas pu extraire un pixel dont la valeur de pixel satisfait la condition de seuil, et pour sélectionner un pixel de projection parmi les pixels sur la ligne de projection selon la distance à partir de la surface de projection si l'unité d'extraction de pixel a pu extraire un pixel dont la valeur de pixel satisfait la condition de seuil.
PCT/JP2010/058265 2009-05-18 2010-05-17 Dispositif d'affichage d'image médicale et procédé d'affichage d'image médicale WO2010134481A1 (fr)

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CN201080020112.3A CN102421367B (zh) 2009-05-18 2010-05-17 医用图像显示装置及医用图像显示方法
JP2011514396A JP5701208B2 (ja) 2009-05-18 2010-05-17 医用画像表示装置及び医用画像表示方法

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Publication number Priority date Publication date Assignee Title
JP2013017619A (ja) * 2011-07-11 2013-01-31 Canon Inc 眼科画像処理装置、眼科画像処理方法、該方法を実行させるためのプログラム、及び記憶媒体
CN104902818A (zh) * 2013-02-05 2015-09-09 株式会社日立医疗器械 X射线ct装置以及图像重构方法
JP2016007502A (ja) * 2014-06-26 2016-01-18 株式会社東芝 医用画像処理装置及び医用画像処理方法

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JPH07129786A (ja) * 1993-11-02 1995-05-19 Toshiba Medical Eng Co Ltd 画像表示装置
JPH10171976A (ja) * 1996-10-07 1998-06-26 Ge Yokogawa Medical Syst Ltd 画像処理方法及び画像処理装置

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JP4327171B2 (ja) * 2006-04-06 2009-09-09 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー 最大値投影方法および装置

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JPH03147082A (ja) * 1989-11-01 1991-06-24 Hitachi Ltd ３次元データ表示方法
JPH07129786A (ja) * 1993-11-02 1995-05-19 Toshiba Medical Eng Co Ltd 画像表示装置
JPH10171976A (ja) * 1996-10-07 1998-06-26 Ge Yokogawa Medical Syst Ltd 画像処理方法及び画像処理装置

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Publication number Priority date Publication date Assignee Title
JP2013017619A (ja) * 2011-07-11 2013-01-31 Canon Inc 眼科画像処理装置、眼科画像処理方法、該方法を実行させるためのプログラム、及び記憶媒体
CN104902818A (zh) * 2013-02-05 2015-09-09 株式会社日立医疗器械 X射线ct装置以及图像重构方法
JP2016007502A (ja) * 2014-06-26 2016-01-18 株式会社東芝 医用画像処理装置及び医用画像処理方法

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