WO2010117982A9 - Ancrage de greffe de tissu - Google Patents

Ancrage de greffe de tissu Download PDF

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Publication number
WO2010117982A9
WO2010117982A9 PCT/US2010/030043 US2010030043W WO2010117982A9 WO 2010117982 A9 WO2010117982 A9 WO 2010117982A9 US 2010030043 W US2010030043 W US 2010030043W WO 2010117982 A9 WO2010117982 A9 WO 2010117982A9
Authority
WO
WIPO (PCT)
Prior art keywords
anchor
polymer material
bone
tissue graft
hole
Prior art date
Application number
PCT/US2010/030043
Other languages
English (en)
Other versions
WO2010117982A1 (fr
Inventor
Horacio De Oca Montes
Malcolm Brown
Michael Hall
Graeme Howling
Original Assignee
Smith & Nephew, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith & Nephew, Inc. filed Critical Smith & Nephew, Inc.
Priority to JP2012504762A priority Critical patent/JP5735487B2/ja
Priority to EP10715000.5A priority patent/EP2416735B1/fr
Priority to AU2010234613A priority patent/AU2010234613B2/en
Priority to CN201080015952.0A priority patent/CN102596099B/zh
Publication of WO2010117982A1 publication Critical patent/WO2010117982A1/fr
Publication of WO2010117982A9 publication Critical patent/WO2010117982A9/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0847—Mode of fixation of anchor to tendon or ligament
    • A61F2002/0852—Fixation of a loop or U-turn, e.g. eyelets, anchor having multiple holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0847—Mode of fixation of anchor to tendon or ligament
    • A61F2002/0858—Fixation of tendon or ligament between anchor and bone, e.g. interference screws, wedges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0876—Position of anchor in respect to the bone
    • A61F2002/0888—Anchor in or on a blind hole or on the bone surface without formation of a tunnel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30077—Properties of materials and coating materials shrinkable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0066—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof shrinkable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter

Definitions

  • the present disclosure relates to tissue graft fixation.
  • a ligament such as an anterior cruciate ligament (ACL) that has ruptured and is non-repairable, is generally replaced arthroscopically by a tissue graft.
  • the tissue graft can be harvested from a portion of a patellar tendon having so called “bone blocks" at each end, and from the semitendonosis and gracilis.
  • the tissue graft can be formed from synthetic materials or from a combination of synthetic and natural materials.
  • the replacement tissue graft is implanted by securing one end of the tissue graft in a socket formed in a passage within the femur, and passing the other end of the graft through a passage formed in the tibia.
  • sutures are used to affix each end of the tissue graft to an anchor (e.g., an interference screw or a post), which is then secured to the bone.
  • an anchor e.g., an interference screw or a post
  • disadvantages of a traditional interference screw include the requirement of a range of screw sizes for different patients, the lack of 360° contact of the screw with the treatment area, tendon slippage, and a low fixation force by the screw on the tendon.
  • the present disclosure relates to a method of fixating a tissue graft.
  • the method includes creating a hole in bone; inserting a tissue graft into the hole; inserting a cannulated anchor into the hole, the anchor including threads on an outer surface of the anchor and a polymer material including shape memory qualities; and providing energy to the anchor to deform the anchor and fixate the anchor to the bone, wherein upon deformation of the anchor, a depth of each thread of the anchor is substantially reduced thereby increasing contact between the anchor and the tissue graft.
  • the bone includes a femur. In another embodiment, the bone includes a tibia.
  • the polymer material is selected from a group including an amorphous polymer, a semi-crystalline polymer, and combinations thereof. In a further embodiment, the polymer material includes a resorbable polymer material. In yet a further embodiment, the polymer material includes a non-resorbable polymer material. In an embodiment, a pitch of each thread of the anchor is substantially reduced. In another embodiment, the source of energy includes body temperature.
  • the present disclosure relates to an anchor.
  • the anchor includes a proximal portion; a distal portion having threads; a middle portion located between the proximal portion and the distal portion, the middle portion including a diameter that is smaller than a diameter of the proximal portion and the distal portion; and a polymer material coupled to the middle portion, the polymer material having shape memory qualities.
  • the present disclosure relates to an anchor.
  • the anchor includes threads on an outer surface of the anchor and a polymer material including shape memory qualities, wherein upon providing the anchor with energy, the anchor deforms such that a depth of each thread of the anchor is substantially reduced.
  • a pitch of each thread is substantially reduced.
  • the source of energy includes body temperature.
  • the present disclosure relates to an anchor.
  • the anchor includes a proximal portion, a distal portion, a cannulation, and an outer surface including a plurality of barbs and a plurality of grooves, the grooves extending an entire length of the anchor, wherein the anchor includes a polymer material having shape memory qualities.
  • Fig. 1 shows a flow chart of the method of the present disclosure.
  • FIGs. 2A-2B illustrate an embodiment of the method of Fig. 1.
  • FIG. 3 shows a cross-sectional view of a first embodiment of a tissue graft anchor of the present disclosure.
  • Figs. 4A-4B show a second embodiment of a tissue graft anchor of the present disclosure.
  • Figs. 5A-5B show the tissue graft anchor of Figs. 4A-4B after insertion of the anchor into bone and providing the anchor with energy.
  • Fig. 1 shows a flow chart of the method 10 of the present disclosure.
  • the method 10 includes creating a hole in bone 11; inserting a tissue graft into the hole 12; inserting an anchor into the hole 13; and providing energy to the anchor to deform the anchor and fixate the tissue graft to the bone 14.
  • FIG. 2A shows ends 21 of a tissue graft 20 housed within a bone tunnel 31 and an anchor 40 disposed between the ends 21. Creation of the bone tunnel 31 and insertion of the tissue graft 20 into the bone tunnel 31 may be done via any method known to one of skill in the art.
  • the anchor 40 includes a proximal end 41 and a distal end 42. In addition, the anchor 40 is tapered from the proximal end 41 to the distal end 42. A cannulation 43 exists along the entire length of the anchor 40. However, an anchor having a cannulation extending a partial length of the anchor is also within the scope of this disclosure. Furthermore, the anchor 40 mcludes an outer surface 44 having threads 45.
  • the anchor 40 is inserted into the bone tunnel 31, via a rotary motion, using any instrument known to one of skill in the art for inserting an anchor into bone.
  • the anchor 40 includes a resorbable polymer material having shape memory qualities.
  • Specific polymers that may be used include polyetheretherketone (PEEK), polymethyl methacrylate (PMMA), polyethyl methacrylate (PEMA), polyacrylate, poly-alpha-hydroxy acids, polycapropactones, polydioxanones, polyesters, polyglycolic acid, polyglycols, polylactides, polyorthoesters, polyphosphates, polyoxaesters, polyphosphoesters.
  • bioactive agents may be incorporated into the polymer material to be released during the deformation or the degradation of the polymer material. These agents are included to help promote bone regrowth.
  • the polymeric materials can be formed as a composite or matrix and include reinforcing material or phases such as fibers, rods, platelets, and fillers.
  • the polymeric material can include glass fibers, carbon fibers, polymeric fibers, ceramic fibers, or ceramic particulates, Other reinforcing material or phases known to one of ordinary skill in the art could also be used.
  • hydrophilic materials may be included in the polymer matrix to accelerate water ingress and hence the relaxation rate of the polymer material.
  • hydrophilic materials include, as stated above, polyethylene glycol. Other hydrophilic materials known to one of ordinary skill in the art may also be used.
  • the oriented polymer material may also include a porogen, such as sodium chloride. Other porogens known to one of ordinary skill in the art may also be used.
  • the porogen may then be washed out of the material leaving pores that will aid water penetration and hence accelerate the relaxation rate of the material. Porogens may be included in the polymer material and washed out to leave pores before the material is oriented.
  • channels will develop in the material, due to an increase in surface area, to aid in water penetration and relaxation rate. Since the rate of relaxation is dependent upon the diffusion rate of fluid into the polymer, the addition of these channels, pores, porogens, and hydrophilic units enhances the rate of relaxation of these materials.
  • Factors used to determine the type of polymer used include, but are not limited to, the desired amount of polymer deformation, the desired rate at which that deformation occurs, the rate at which the polymer is absorbed, and the strength of the polymer.
  • polymers that display shape memory qualities show a large change in modulus of elasticity at the glass transition temperature (T g ),
  • the shape-memory function can be achieved by taking advantage of this characteristic. Namely, a polymer material having a first shape (original shape) is processed to produce an article with a second shape (defined shape). This process also provides the material with its shape memory qualities by imparting an orientation to the polymer chains of the material. The article is then provided with energy to heat the article to a temperature (T f ) higher than the T g of the polymer, but lower than the melting temperature (T ra ) thereof so as to deform the article and return it to its original shape.
  • T f temperature
  • T ra melting temperature
  • the anchor 40 shown in Fig. 2A represents the article described above having the defined shape. Once the anchor 40 has been provided with energy, it is deformed, as shown in Fig. 2B, to return the anchor 40 to its original shape, Upon deformation, the anchor 40 changes shape by shrinking axially, or along the length of the material, and expanding radially, or along the width of the material. This expansion and shrinkage causes the anchor 40 to engage the ends 21 of the tissue graft 20 and force the ends 21 towards the wall 32 of the bone tunnel 31, thereby fixating the tissue 20 to the bone 30. In addition to this shrinkage and expansion, upon deformation, a depth and pitch of each thread of the anchor 40 is substantially reduced thereby increasing contact between the anchor and the tissue graft.
  • An energy source that may be used to deform the anchor 40 includes a heated liquid, such as saline or water.
  • the liquid may be introduced into the bone tunnel 31 via a syringe or other delivery device.
  • an electrosurgical heating probe such as the electrosurgical heating probes described in International Patent Application Publication WO 2008/112880, the disclosure of which is incorporated herein by reference in its entirety, may also be used. It is also within the scope of this disclosure that once the anchor 40 is placed in the bone, body heat would be transferred from blood and tissue, via thermal conduction, to provide the energy necessary to deform the anchor 40. hi this instance, body temperature would be used as a thermal energy source.
  • the anchor 40 may be formed by die-drawing, extrusion, cold forging, or molding (i.e. compression flow molding or thermoforming process) the above-mentioned polymers or polymer compositions. Other solid-state processing methods may also be used.
  • FIG. 3 shows a cross-sectional view of an anchor 60 including a body 60a having a proximal portion 61, a distal portion 62 having threads 62a, and a middle portion 63 located between the proximal portion 61 and the distal portion 62.
  • the middle portion 63 includes a diameter that is smaller than a diameter of the proximal portion 61 and the distal portion 62,
  • a sleeve 64 of polymer material is coupled to the middle portion 63.
  • the sleeve 64 includes a proximal end 64a, a distal end 64b, and a cannulation 64c.
  • the polymer material includes shape memory qualities.
  • the anchor 60 may be used in coupling tissue to bone by inserting the anchor 60 into a bone tunnel and providing the anchor 60 and, specifically the sleeve 64, with energy to expand the sleeve 64 and fixate the tissue to bone, similar to what has been described above.
  • the body 60a of the anchor 60 rotates and the sleeve 64 remains static, thereby allowing the tissue to remain in alignment with the anchor 60.
  • Figs. 4A-4B show an anchor 100 including a proximal portion 101, a distal portion 102, a cannulation 103, and an outer surface 104 including barbs 105 and grooves 106.
  • the grooves 106 extend an entire length of the anchor 100 and are more clearly shown in Fig. 4B.
  • the anchor 100 includes a polymer material having shape memory qualities.
  • the anchor 100 is inserted into a prepared bone tunnel 107, subsequent to insertion of soft tissue 108 into the bone tunnel 107, such that the ends 108a,108b of the tissue 108 are housed within the grooves 106.
  • the tunnel 107 includes an undercut portion 107a, as shown more clearly in Fig. 5A, for purposes to be further described below.
  • the anchor 100 is provided with energy, via a method described above, to deform the anchor 100, thereby causing the anchor 100 to engage the ends 108a,108b of the soft tissue 108 and force the ends 108a,108b towards the wall 107b of the tunnel 107, as shown more clearly in Fig, 5B. Also shown in Fig. 5B is the expansion of the anchor 100 into the undercut portions 107a. It is believed that expansion of the anchor 100 and, therefore the ends 108a,108b, into the undercut portions 107a will serve to lock the ends 108a,108b within the portion 107a, thereby further increasing fixation of the tissue 108 within the bone tunnel 107. Furthermore, the barbs 105 provide for more secure engagement of the soft tissue 108 and, therefore, increased fixation of the soft tissue 108 to the bone tunnel 107. EXAMPLE ONE
  • a polymer rod having shape memory qualities and a diameter of about 15 mm, was produced by die drawing a 30 mm diameter billet of Poly(D,L-lactide-co-glycolide) 85:15 containing 35% 7 W NaCl through a 15 mm die.
  • the polymer rod was machined to produce several samples, each of which had a diameter about 13 mm and a length of about 35 mm.
  • a mold with two symmetrical halves and a threaded hole of length 41.35 mm and diameter 13.78 mm (narrowest part of thread) was clamped shut and heated to 80°C in an oven, A machined sample was placed in the threaded hole of the mold and heated in the oven for 2.5 minutes.
  • the mold was then removed from the oven and crash cooled by immersion in liquid N 2 . Once the mold had cooled it was removed from the liquid N 2 and opened.
  • the sample had shape recovered to take the shape of the threaded hole in the mold.
  • the molded sample was cut in half and one half was placed in hot water at approx. 90°C and removed once the shape recovery process had stopped. Once the sample was dry, its diameter was measured as 22.7 mm, having recovered to 87% of the theoretical recovery diameter. The pitch and the depth of the threads introduced during the molding process had also been substantially reduced.
  • a second molded sample was inserted into a hole of a second sawbone in the same manner as described above, without providing the sample with energy.
  • the ropes were removed from the hole by pulling on the rope ends and the pull-out force was tested.
  • the pull-out force for the second sample was 500 N.
  • the deformed sample did provide for substantial fixation of the ropes to the bone as compared to the control sample, which was reflected in the amount of increase in pull-out force between the two samples.

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rehabilitation Therapy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

La présente invention concerne un procédé de fixation d'une greffe de tissu. Le procédé comprend la formation d'un trou dans un os; l'insertion d'une greffe de tissu dans le trou; l'insertion d'un ancrage canulé dans le trou, l'ancrage comprenant des filetages sur une surface extérieure de l'ancrage et un matériau polymère comprenant des qualités de mémoire de forme; et l'apport d'énergie à l'ancrage pour déformer l'ancrage et fixer l'ancrage à l'os. Après déformation de l'ancrage, les filetages de l'ancrage sont sensiblement réduits de manière à augmenter le contact entre l'ancrage et la greffe de tissu. Des ancrages sont également décrits.
PCT/US2010/030043 2009-04-06 2010-04-06 Ancrage de greffe de tissu WO2010117982A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2012504762A JP5735487B2 (ja) 2009-04-06 2010-04-06 組織移植片アンカー
EP10715000.5A EP2416735B1 (fr) 2009-04-06 2010-04-06 Ancrage de greffe de tissu
AU2010234613A AU2010234613B2 (en) 2009-04-06 2010-04-06 Tissue graft anchor
CN201080015952.0A CN102596099B (zh) 2009-04-06 2010-04-06 组织移植物锚定器

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16690809P 2009-04-06 2009-04-06
US61/166,908 2009-04-06

Publications (2)

Publication Number Publication Date
WO2010117982A1 WO2010117982A1 (fr) 2010-10-14
WO2010117982A9 true WO2010117982A9 (fr) 2012-05-03

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/030043 WO2010117982A1 (fr) 2009-04-06 2010-04-06 Ancrage de greffe de tissu

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EP (1) EP2416735B1 (fr)
JP (1) JP5735487B2 (fr)
CN (1) CN102596099B (fr)
AU (1) AU2010234613B2 (fr)
WO (1) WO2010117982A1 (fr)

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ES2853202T3 (es) 2010-01-27 2021-09-15 Sportwelding Gmbh Elemento de sujeción adecuado para sujetar un tejido o un elemento protésico correspondiente en una abertura proporcionada en un hueso humano o animal
EP3639756B1 (fr) 2010-09-24 2023-01-04 Sportwelding GmbH Ancrage pour la fixation d'une suture à des tissus durs
CN107296633B (zh) 2010-09-24 2020-08-11 斯博特威尔丁股份有限公司 缝线锚钉和用于相对硬组织固定缝线的方法
KR20190079691A (ko) 2011-01-28 2019-07-05 스포트벨딩 게엠베하 봉합사를 갖춘 봉합 앵커 또는 머리붙이 앵커를 경조직 내에 고정시키기 위한 장치 및 방법
US9386976B2 (en) 2011-01-28 2016-07-12 Sportwelding Gmbh Method and device for fixating a suture anchor with a suture in hard tissue
EP2734136B1 (fr) 2011-07-18 2021-10-27 Sportwelding GmbH Élément de fixation pour un greffon de tissu mou dans une ouverture ménagée dans un os d'être humain ou d'animal
WO2018102104A2 (fr) * 2016-11-30 2018-06-07 Acuitive Technologies, Inc. Ancres déformables bio-absorbables

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JPH10305043A (ja) * 1997-05-06 1998-11-17 Terumo Corp 骨固定具及びその製造方法
ATE274877T1 (de) * 1999-10-06 2004-09-15 Astra Tech Ab Hüftschaft und satz von hüftschäften
EP1501424B1 (fr) * 2002-04-18 2018-06-06 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Sutures polymeres a memoire de forme biodegradables
WO2006108114A2 (fr) * 2005-04-01 2006-10-12 The Regents Of The University Of Colorado Dispositif et procede de fixation de greffe
EP1749490B1 (fr) * 2005-08-05 2008-11-19 BIEDERMANN MOTECH GmbH Elément d'ancrage osseux
US20080234730A1 (en) * 2007-03-23 2008-09-25 Smith & Nephew, Inc. Fixation Devices and Method of Repair
WO2008130954A2 (fr) * 2007-04-19 2008-10-30 Smith & Nephew, Inc. Fixation de greffe

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CN102596099A (zh) 2012-07-18
JP5735487B2 (ja) 2015-06-17
EP2416735B1 (fr) 2013-07-17
JP2012522622A (ja) 2012-09-27
CN102596099B (zh) 2015-08-12
WO2010117982A1 (fr) 2010-10-14
AU2010234613A1 (en) 2011-10-27
AU2010234613B2 (en) 2015-12-17
EP2416735A1 (fr) 2012-02-15

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