WO2010117241A2 - 비후성 반흔 또는 켈로이드 예방 또는 치료용 조성물 - Google Patents

비후성 반흔 또는 켈로이드 예방 또는 치료용 조성물 Download PDF

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Publication number
WO2010117241A2
WO2010117241A2 PCT/KR2010/002210 KR2010002210W WO2010117241A2 WO 2010117241 A2 WO2010117241 A2 WO 2010117241A2 KR 2010002210 W KR2010002210 W KR 2010002210W WO 2010117241 A2 WO2010117241 A2 WO 2010117241A2
Authority
WO
WIPO (PCT)
Prior art keywords
composition
keloids
prevention
treatment
general formula
Prior art date
Application number
PCT/KR2010/002210
Other languages
English (en)
French (fr)
Other versions
WO2010117241A3 (ko
Inventor
강승우
Original Assignee
주식회사 베네비오
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 베네비오 filed Critical 주식회사 베네비오
Priority to US13/376,463 priority Critical patent/US8877736B2/en
Publication of WO2010117241A2 publication Critical patent/WO2010117241A2/ko
Publication of WO2010117241A3 publication Critical patent/WO2010117241A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

본 발명은 유효성분으로서 다음 일반식 I로 표시되는 화합물을 포함하는 비후성 반흔 또는 켈로이드(keloid) 예방 또는 치료용 조성물에 관한 것이다: [일반식 I] S-(MS)p-(MS)q 상기 일반식에서, S는 시알간, (MS)p 및 (MS)q는 서로 독립적으로 단당류 잔기이다. 본 발명의 조성물은 켈로이드 섬유아세포의 증식을 효과적으로 억제할 뿐만 아니라 아폽토시스를 유도하여 켈로이드를 매우 효과적으로 치료할 수 있다. 본 발명의 유효성분은 천연 유래 물질 또는 그의 이성질체로서 인체에 대한 부작용이 매우 적다.
PCT/KR2010/002210 2009-04-09 2010-04-09 비후성 반흔 또는 켈로이드 예방 또는 치료용 조성물 WO2010117241A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/376,463 US8877736B2 (en) 2009-04-09 2010-04-09 Method for treating keloid by administering 3′sialyllactose or 6′sialyllactose as a pharmaceutical or cosmetic

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0030995 2009-04-09
KR1020090030995A KR101112051B1 (ko) 2009-04-09 2009-04-09 비후성 반흔 또는 켈로이드 예방 또는 치료용 조성물

Publications (2)

Publication Number Publication Date
WO2010117241A2 true WO2010117241A2 (ko) 2010-10-14
WO2010117241A3 WO2010117241A3 (ko) 2011-03-31

Family

ID=42936746

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/002210 WO2010117241A2 (ko) 2009-04-09 2010-04-09 비후성 반흔 또는 켈로이드 예방 또는 치료용 조성물

Country Status (3)

Country Link
US (1) US8877736B2 (ko)
KR (1) KR101112051B1 (ko)
WO (1) WO2010117241A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3403655B1 (en) * 2016-01-13 2023-06-07 Benebiosis Co., Ltd. Composition for increasing expression of pgc-1 alpha
KR101800788B1 (ko) * 2017-03-31 2017-11-27 박영오 켈로이드 흉터 개선용 화장료 조성물
KR102577970B1 (ko) 2021-08-10 2023-09-12 충남대학교병원 켈로이드 예방 또는 치료용 조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6576251B1 (en) * 1997-01-16 2003-06-10 N. V. Nutricia Carbohydrate mixture

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839053A2 (en) * 1995-07-14 1998-05-06 GlycoTech Corp. Compounds and methods for treatment of egf receptor associated cancers and purification of the egf receptor
WO1998048817A1 (en) * 1997-05-01 1998-11-05 Cytel Corporation Use of sialyl galactosides and related compounds as anti-angiogenic agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6576251B1 (en) * 1997-01-16 2003-06-10 N. V. Nutricia Carbohydrate mixture

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AMERICAN SOCIETY FOR DERMATOLOGIC SURGERY ET AL.: 'English RS and Shenefelt PD, Keloids and hypertrophic scars.' DERMATOLOGIC SURGERY vol. 25, 1999, pages 631 - 638 *
DADDAOUA A. ET AL.: 'Goat Milk Oligosaccharides Are Anti-Inflammatory in Rats with Hapten-Induced Colitis.' THE JOURNAL OF NUTRITION vol. 136, no. 3, 2006, pages 672 - 676 *
KUNTZ S. ET AL.: 'Oligosaccharides from human milk influence growth-related characteristics of intestinally transformed and non-transformed intestinal cells.' THE BRITISH JOURNAL OF NUTRITION vol. 99, no. 3, 2008, pages 462 - 471 *

Also Published As

Publication number Publication date
KR20100112469A (ko) 2010-10-19
US20120122814A1 (en) 2012-05-17
WO2010117241A3 (ko) 2011-03-31
KR101112051B1 (ko) 2012-02-14
US8877736B2 (en) 2014-11-04

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