WO2010107285A3 - Volume production method for growth factor using mesenchymal stem cells derived from the fetus in amniotic fluid - Google Patents

Volume production method for growth factor using mesenchymal stem cells derived from the fetus in amniotic fluid Download PDF

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Publication number
WO2010107285A3
WO2010107285A3 PCT/KR2010/001728 KR2010001728W WO2010107285A3 WO 2010107285 A3 WO2010107285 A3 WO 2010107285A3 KR 2010001728 W KR2010001728 W KR 2010001728W WO 2010107285 A3 WO2010107285 A3 WO 2010107285A3
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WO
WIPO (PCT)
Prior art keywords
fetus
stem cells
mesenchymal stem
cells derived
amniotic fluid
Prior art date
Application number
PCT/KR2010/001728
Other languages
French (fr)
Korean (ko)
Other versions
WO2010107285A2 (en
Inventor
유승권
윤병선
전은경
문재희
김종건
정혜연
이중한
박을순
맹이삭
김준성
이장호
이황희
이종원
조경식
Original Assignee
주식회사 스템메디언스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 스템메디언스 filed Critical 주식회사 스템메디언스
Publication of WO2010107285A2 publication Critical patent/WO2010107285A2/en
Publication of WO2010107285A3 publication Critical patent/WO2010107285A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)

Abstract

The present invention relates to mesenchymal stem cells derived from the fetus in amniotic fluid and more specifically to mesenchymal stem cells derived from the fetus in amniotic fluid, a method for making the same, a conditioned culture medium composition made using the same, and a volume production method for human growth factor.
PCT/KR2010/001728 2009-03-20 2010-03-19 Volume production method for growth factor using mesenchymal stem cells derived from the fetus in amniotic fluid WO2010107285A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0024054 2009-03-20
KR1020090024054A KR101119225B1 (en) 2009-03-20 2009-03-20 Large scale production of growth promoting factors using fetus-derived mesenchymal stem cells from amniotic fluids

Publications (2)

Publication Number Publication Date
WO2010107285A2 WO2010107285A2 (en) 2010-09-23
WO2010107285A3 true WO2010107285A3 (en) 2011-01-27

Family

ID=42740150

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/001728 WO2010107285A2 (en) 2009-03-20 2010-03-19 Volume production method for growth factor using mesenchymal stem cells derived from the fetus in amniotic fluid

Country Status (2)

Country Link
KR (1) KR101119225B1 (en)
WO (1) WO2010107285A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101371690B1 (en) * 2011-07-12 2014-03-12 주식회사 스템메디언스 Large scale production of growth promoting factors using fetus-derived mesenchymal stem cells from amniotic fluids with hypoxic condition and composition for regenerating skin using the same
KR101354826B1 (en) * 2011-12-08 2014-01-27 아주대학교산학협력단 Screening method of the materials for prevention or treatment of osteoporosis using leptin production in mesenchymal stem cell
KR102126331B1 (en) * 2012-02-23 2020-06-25 주식회사 탑셀바이오 Method for preparing conditioned medium powder
KR101566450B1 (en) * 2015-04-03 2015-11-05 (유)스템메디케어 A Method for mass production of proteins from mesenchymal stem cells
KR102522295B1 (en) * 2022-08-30 2023-04-18 주식회사 스마트셀랩 Isolation and culture conditions of peripheral blood-derived stem cells and induction of differentiation into progenitor cells using them

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050054093A1 (en) * 2003-08-14 2005-03-10 Martin Haas Multipotent amniotic fetal stem cells
WO2008036447A2 (en) * 2006-06-26 2008-03-27 Lifescan, Inc. Pluripotent stem cell culture

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050054093A1 (en) * 2003-08-14 2005-03-10 Martin Haas Multipotent amniotic fetal stem cells
WO2008036447A2 (en) * 2006-06-26 2008-03-27 Lifescan, Inc. Pluripotent stem cell culture

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HUMAN REPRODUCTION, vol. 19, no. 6, 2004, pages 1450 - 1456 *
NATURE BIOTECH., vol. 25, no. 1, January 2007 (2007-01-01), pages 100 - 106 *

Also Published As

Publication number Publication date
KR101119225B1 (en) 2012-03-20
WO2010107285A2 (en) 2010-09-23
KR20100105165A (en) 2010-09-29

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