WO2010093065A1 - Cosmetic composition containing herbal peeling powder having dds mechanism - Google Patents

Cosmetic composition containing herbal peeling powder having dds mechanism Download PDF

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Publication number
WO2010093065A1
WO2010093065A1 PCT/KR2009/000601 KR2009000601W WO2010093065A1 WO 2010093065 A1 WO2010093065 A1 WO 2010093065A1 KR 2009000601 W KR2009000601 W KR 2009000601W WO 2010093065 A1 WO2010093065 A1 WO 2010093065A1
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Prior art keywords
skin
herbal
cosmetic composition
composition containing
powder
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PCT/KR2009/000601
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French (fr)
Korean (ko)
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김태곤
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(주)파이온텍
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Priority to JP2011549049A priority Critical patent/JP5479498B2/en
Priority to PCT/KR2009/000601 priority patent/WO2010093065A1/en
Publication of WO2010093065A1 publication Critical patent/WO2010093065A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants

Definitions

  • the present invention relates to a cosmetic composition that improves stimulation and efficacy, effects and ease of use containing herbal peeling powder for exfoliation and skin regeneration having a drug delivery system (DDS) mechanism.
  • herbal powders which are commercially available as commercial products and sold in herbal powders, are mixed with herbal powders such as xanthan gum, hydrophilic moisturizers, skin regeneration / functional ingredients or natural anti-inflammatory ingredients, and natural herb oil.
  • Herbal peeling with DDS mechanism that can be added and contained to make it convenient to use without skin irritation, safe and effective to remove dead skin, and improve wrinkles, elasticity and whitening effect by skin regeneration It relates to a cosmetic composition containing a powder.
  • Skin protects the human body from the external environment and is the most important biochemical and physical tissue. It is divided into epidermis, dermis and hypodermis.
  • the stratum corneum the outermost layer of skin, has a barrier against moisture evaporation and absorption of the skin and penetration of external substances such as chemicals, toxic substances and bacteria.
  • keratinocytes produced in the basal layer take up to 14 days to the granular layer.
  • keratin hyalin (Keratohyalin) action of the keratin starts the body fluid in the cell is released and the cells are flattened in a flat state. These cells release millions of dead keratinocytes from the skin and replace them with keratinocytes per day.
  • the epidermal layer is peeled by various methods such as peeling products, dermabrasion and chemical peeling to stimulate cell division and proliferation in the basal layer so that young and healthy cells are produced.
  • Exfoliating cosmetics developed so far can be divided into three functional groups according to the mechanism of exfoliation action.
  • the first is an exfoliation product using a scrub having exfoliation function by a physical action such as skin friction or a laser to finely cut the epidermis.
  • the second is an exfoliation effect by chemical action.
  • Products containing chemical ingredients such as AHA ( ⁇ -hydroxy Acid), BHA ( ⁇ -hydroxy acid), and urea, which have keratin soluble effects.
  • AHA ⁇ -hydroxy Acid
  • BHA ⁇ -hydroxy acid
  • urea which have keratin soluble effects.
  • Third the action of proteolytic enzymes that exfoliate by physiological action It is a product that exfoliates keratin by applying.
  • Herbal Powder products containing a mixture of nine kinds of herbal powders, such as horsetail, sage, witch hazel, marshmallow, scabbard, It contains spirulina, calendula, lemon balm and fenugreek.
  • the exfoliation method of this product massages various kinds of herbal ingredients to be absorbed into the skin and induces blood circulation primarily, and at the same time promotes the regeneration of cells in the skin to induce the exfoliation within 3 to 5 days. It is.
  • the skin has a significant irritation when applied to the skin, resulting in red swelling of the skin. If not, it will also occur.
  • an object of the present invention is to improve the discomfort and swelling caused by the skin irritation of natural herbal powders, DDS having a hypoallergenic and excellent exfoliation function and wrinkle improvement by skin regeneration, elasticity and whitening effect It is to provide a cosmetic composition containing a herbal peeling powder having a mechanism.
  • MTS systems that increase the absorption efficiency by nanoscopicizing the particle size of the functional material and absorbing it between the cell gaps, rather than through the existing pores, and absorbing the functional material through the gaps by drilling fine holes in the skin.
  • this method incurs the cost burden along with the technical difficulty according to the additional process of liposome encapsulation separately to increase the intimacy with the skin in the process of nanoparticles of functional material, and in the case of MTS to reduce the pain suffered by the subject In order to create a cumbersome process that requires a separate anesthesia process.
  • the present invention maximizes the dermal absorption without any additional process by maximizing the absorption of dermis without any additional process by implanting the functional material was absorbed into the needle structure component on the cosmetic composition on the cosmetic composition when applying the herbal powder to the skin Its purpose is to provide additional features such as elasticity and stretch marks.
  • an object of the present invention is a cosmetic composition that improves discomfort in use due to skin irritation and swelling due to skin irritation of natural herbal powders, and a powdered herbal powder (Herbal Powder) in xanthan gum,
  • a powdered herbal powder Herbal Powder
  • a hydrophilic moisturizer By adding and containing a hydrophilic moisturizer, skin regeneration / functional ingredient or natural anti-inflammatory ingredient and natural herb oil in predetermined ratios, it is convenient to use without skin irritation, and it can be removed safely and effectively. Wrinkle improvement, elasticity and whitening effect by regeneration are excellent, and needle powder structure of Herbal Powder acts as a new concept DDS (Drug Delivery System) mechanism to provide functional ingredients effectively to the skin.
  • DDS Drug Delivery System
  • Cosmetic composition containing a herbal peeling powder having a DDS mechanism of the present invention for achieving the above object is 0.1 ⁇ 5% by weight of xanthan gum, 0.1 ⁇ 5% by hydrophilic moisturizer relative to 10 to 50% by weight of the herbal powder commercially available for sale 20 to 20% by weight, skin regeneration / functional ingredient or 0.1 to 5% by weight of natural anti-inflammatory ingredient, 0.001 to 0.1% of natural herb oil and the remaining purified water were mixed and liquefied by applying 0.8 ⁇ 1.2MHz ultrasonic wave for 3-5 minutes
  • the cosmetic composition has the effect of reducing the stimulation and efficacy, efficacy and ease of use of herbal peeling powder, and the needle-like structure by going through the ultrasonic blending process for applying the DDS mechanism It is characterized in that it is effectively absorbed by the porous surface.
  • Cosmetic composition of the present invention by the action of xanthan gum, hydrophilic moisturizers, skin regeneration / functional ingredients or natural anti-inflammatory ingredients, natural herb oil to make a liquid cosmetic composition of the herbal powders that are irritable to the skin and inconvenient to use It eliminates irritation, provides convenience for use, and exerts an excellent effect on safe and effective exfoliation for skin and wrinkle improvement, elasticity and whitening by skin regeneration.
  • the needle-like powder component of the herbal powder in the cosmetic composition of the present invention is a new concept of the drug delivery system (DDS) mechanism to act directly on the skin, which is a porous surface of the needle-like component extracted from the fresh sea surface of herbal peeling powder
  • DDS drug delivery system
  • the functionalized component or natural anti-inflammatory component is nano-absorbed through the ultrasonic process, and the needle structure is implanted into the skin by massage, and the functional or natural anti-inflammatory component is released from the skin by osmotic pressure and directly into the dermis. It will effectively provide additional skincare features such as acne treatment, skin elasticity and stretch marks.
  • Cosmetic composition improved stimulation and ease of use of herbal peeling powder of the present invention is 0.1 to 5% by weight of xanthan gum, 0.1 to 20% by weight of hydrophilic moisturizer based on 10 to 50% by weight of the herbal powder commercially available as a product , Skin regeneration / functional ingredients or natural anti-inflammatory ingredients 0.1 to 5% by weight, natural herb oil 0.001 to 0.1% and the remaining purified water, in the cosmetic composition, the herbal powder is iron, sage. Witch hazel, marshmallows, plantain, spirulina. Calendula.
  • It contains lemon balm and phenegrig, and when massaged to be absorbed into the skin, it induces blood circulation, and at the same time, promotes the regeneration of cells in the skin and induces exfoliation within 3 to 5 days. It is preferable to use in the range of 10 to 50% by weight to have a new concept DDS mechanism of the needle structure.
  • Xantho gum used in the present invention is a natural mixed substance composed of glucose, mannose and gluconic acid, which are purified, dried and pulverized with a polysaccharide gum material obtained by pure culture fermentation of carbohydrates using Xanthomonas Campestris.
  • Xanthan gum is a component that is used as a stabilizer, thickener, and usability improving agent in cosmetics, including food, because it does not have a viscosity decrease due to pH and is stable within a wide range, and it is preferable to use it in the range of 0.1 to 5% by weight.
  • Hydrophilic moisturizers used in the present invention may be used at least one of butylene glycol, amino acids, glycerin, to prevent skin dryness by herbal powders, and help skin regeneration to further improve the exfoliation function. It is preferable to use in the range of 0.1-20 weight% with respect to the whole composition.
  • the skin regeneration / functional ingredient used in the present invention one or more of ascorbyl glucoside, ascorbic acid, and derivatives thereof may be used, and wound healing may be performed by improving substances or functions necessary for cell regeneration in the human body and enhancing collagen synthesis. Enhance the ability to help skin regeneration by herbal powders can further improve the exfoliation function. In addition, it focuses on the absorption and intimacy of the needle structure so that it can be stably transmitted and absorbed from the DDS mechanism by the herbal powder needle structure to the dermis, and nanoliposomes are formed to maximize the absorption in the dermis, and 0.1 to the whole composition. It is preferable to use in the range of -5 weight%.
  • natural anti-inflammatory ingredients can be used for acne care, which can be used as one or more of extracts from Machi, Alteronas fermented extracts, and pink needle leaf extracts.It inhibits sebum production in hair follicles and causes acne (P. Acne) It provides antimicrobial and anti-inflammatory effects on the hair follicles and removes dead skin cells to prevent clogging of the sebum in the hair follicles can suppress the production of acne and relieve the symptoms of the resulting acne. It is preferable to use it in the range of 0.1-5 weight% with respect to the whole composition.
  • Natural herb oil used in the present invention can be used in one or more of eucalyptus, tea tree, orange sweet and rejuvenate skin relieve effect, anti-inflammatory, relieves stress and tension, and above all for skin It can improve the function of exfoliation by regenerating effect.
  • tea tree has its own antibacterial effect, which is effective for removing acne. It is preferable to use in the range of 0.001-0.1 weight% with respect to the whole composition.
  • a blending process through ultrasonic waves is required in order for the functional ingredient or natural anti-inflammatory ingredient to be effectively absorbed into the pores on the surface of the needle-like component.
  • the pore on the surface of the needle-like component is nano-sized, and the needle-like component is not substituted in the pores with the functional component or natural anti-inflammatory component in the normal state of the same size of air bubbles that occupy the inside of the pore. Implantation into the skin will not allow the DDS mechanism to be exercised.
  • the cavitation effect of the ultrasonic waves effectively replaces the functional or natural anti-inflammatory components with air particles in the surface pores of the needle structure components. Will be absorbed.
  • the DDS mechanism is not properly exhibited, so it is preferable to maintain the above conditions.
  • the cosmetic composition according to the present invention can be packaged in an airtight ampoule container to prevent microbial contamination from the outside environment, increase storage stability, and significantly increase the shelf life and prevent the occurrence of hygiene problems due to repeated use. have.
  • compositions having excellent whitening effect by exfoliation and skin cell regeneration by stimulating medicinal herbs and improving convenience of use were prepared in Tables 1 and 2, and compositions for acne treatment according to Table 3. 1 to 7 were applied to the experiment after applying the mixture of each component to the ultrasonic wave in the range of 0.8 to 1.2MHz for 3-5 minutes to exert the DDS mechanism.
  • Example 1 or Example 3 For 10 women aged 20 to 50 years, each of the products of Example 1 or Example 3 was applied to the left side of the face, and each product of Example 1 or Example 3 was applied to the right side of the face, and then the dead skin was removed. 5 days after the skin was regenerated and completed, the melanin index was measured by using a melanin-erythema index meter on both sides of the face, and the results were shown before and after using the product.
  • the cosmetic composition of the present invention eliminates irritation to the skin, provides convenience for use, and is excellent for wrinkle improvement, elasticity and whitening by safe and effective exfoliation and skin regeneration for the skin.
  • the cosmetic composition of the present invention effectively provides additional skin care functions such as acne treatment, skin elasticity, stretch marks.

Abstract

The present invention provides a cosmetic composition containing a herbal peeling powder for dead cell removal and skin regeneration with DDS mechanism, in which irritation relief, efficiency, effects, and usability are improved. A xanthan gum, a hydrophilic moisturizer, a skin regenerative/functional ingredient or a natural anti-inflammatory ingredient, and natural herb oil are mixed in a herbal powder by adding in each predetermined ratio, which is a mixture of nine kinds of herbal powders commercialized as a product. Thus, the cosmetic composition enables convenient use without skin irritation and effective removal of dead skin cells while keeping skin safe. Therefore, the cosmetic composition containing a herbal peeling powder has a DDS mechanism with high wrinkle smoothing, elasticity, and whitening effects by skin regeneration.

Description

DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물Cosmetic composition containing herbal peeling powder with DDS mechanism
본 발명은 DDS(Drug Delivery System) 메카니즘을 갖는 각질 제거 및 피부 재생용 약초 필링 분말을 함유하는 자극 완화 및 효능, 효과와 사용 편리성을 개선시킨 화장료 조성물에 관한 것이다. 더욱 상세하게는, 상품으로 상용화되어 판매되고 있는 9종의 약초 분말 혼합물인 허벌파우더(Herbal Powder)에 산탄검, 친수성 보습제, 피부재생/기능성 성분 또는 천연항염성분, 천연허브오일을 각각 소정의 비율로 첨가·함유시켜 배합함으로써 피부의 자극 없이 사용이 편리하고 피부에 안전하면서도 효과적으로 각질이 제거될 수 있도록 하고, 피부 재생에 의한 주름 개선, 탄력 및 미백 효과가 나타날 수 있도록 한 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물에 관한 것이다. The present invention relates to a cosmetic composition that improves stimulation and efficacy, effects and ease of use containing herbal peeling powder for exfoliation and skin regeneration having a drug delivery system (DDS) mechanism. More specifically, herbal powders, which are commercially available as commercial products and sold in herbal powders, are mixed with herbal powders such as xanthan gum, hydrophilic moisturizers, skin regeneration / functional ingredients or natural anti-inflammatory ingredients, and natural herb oil. Herbal peeling with DDS mechanism that can be added and contained to make it convenient to use without skin irritation, safe and effective to remove dead skin, and improve wrinkles, elasticity and whitening effect by skin regeneration It relates to a cosmetic composition containing a powder.
피부는 외부 환경으로부터 인체를 보호하며 생화학적 및 물리학적으로 가장 중요한 조직으로서, 크게 표피(epidermis), 진피(dermis) 그리고 피하(hypodermis)로 나뉘어진다. 피부의 최외각층인 각질층은 피부의 수분증발 및 흡수 조절기능과 화학물질, 독성물질 및 세균 등의 외부물질의 침투에 대한 장벽기능을 가지고 있다. 피부각질층(Stratum Corneum)은 기저층(Basal layer)에서 생산된 각질세포(Keratinocyte)가 14일 걸려 과립층까지 올라온다. 과립층에서는 케라토히알린(Keratohyalin)의 작용으로 각질화가 시작되면 세포속의 체액은 빠져나가 세포는 납작해진 상태로 각질화 된다. 이 세포들은 하루에 수백만개의 죽은 각질세포가 피부에서 떨어져 나가고 세 각질세포로 교체된다.Skin protects the human body from the external environment and is the most important biochemical and physical tissue. It is divided into epidermis, dermis and hypodermis. The stratum corneum, the outermost layer of skin, has a barrier against moisture evaporation and absorption of the skin and penetration of external substances such as chemicals, toxic substances and bacteria. In the stratum corneum, keratinocytes produced in the basal layer take up to 14 days to the granular layer. In the granulation layer, keratin hyalin (Keratohyalin) action of the keratin starts the body fluid in the cell is released and the cells are flattened in a flat state. These cells release millions of dead keratinocytes from the skin and replace them with keratinocytes per day.
성인이 중년에 접어들면 세포의 박리 또는 낙설(Desquamation)이 제대로 이루어지지 않아 세포 재생 회전주기(Cell Tunover Cycle)가 길어지면서 피부가 활력을 잃게 된다. 이것을 방지하고 인위적으로 박리 또는 낙설을 촉진하기 위해 박리제품, 박피수술과 화학적 박리 등 여러 가지 방법으로 표피층을 벗겨내 기저층에서의 세포분열과 증식을 자극시켜 젊고 건강한 세포가 생산되도록 한다.When adults enter middle age, the cells are not detached or desquamated properly, which leads to a prolonged cell tuneover cycle, which causes the skin to lose its vitality. To prevent this and artificially promote peeling or abortion, the epidermal layer is peeled by various methods such as peeling products, dermabrasion and chemical peeling to stimulate cell division and proliferation in the basal layer so that young and healthy cells are produced.
현재까지 개발된 각질제거용 화장품은 그 각질제거 작용기전에 따라 크게 3가지의 기능군으로 구분할 수 있다. 첫 번째는 피부마찰 등 물리적인 작용에 의하여 각질제거 기능을 가지는 스크럽(scrub)을 이용하거나 레이저를 이용하여 표피를 미세하게 깎아내는 방식의 각질제거 제품, 두 번째는 화학적 작용에 의하여 각질제거효능을 가지는 것으로 각질용해 효과가 있는 AHA(α-hydroxy Acid), BHA(β-hydroxy acid), 유레아 등 화학성분을 함유하는 제품, 세 번째는 생리학적 작용에 의하여 각질제거 기능을 가지는 단백질 분해 효소의 작용을 응용하여 각질을 박리시키는 제품이다. 이들 필링 방법들은 피부를 먼저 벗겨낸 후 피부 자체의 재생력을 유도한다는 것이다. 어느 피부든지 일단 어느 정도의 각질이 제거되면 자체적으로 피부 재생을 시작한다. 하지만 필링 그리고 재생이라는 공식은 필링이 된 피부는 재생피부가 올라올 때까지는 외부의 온갖 위험요소에 직접적으로 노출이 되어 있으며 선 필링 후 재생 방식이기 때문에 민감성이거나 예민한 피부에 사용하는 것은 부적절하다.Exfoliating cosmetics developed so far can be divided into three functional groups according to the mechanism of exfoliation action. The first is an exfoliation product using a scrub having exfoliation function by a physical action such as skin friction or a laser to finely cut the epidermis. The second is an exfoliation effect by chemical action. Products containing chemical ingredients such as AHA (α-hydroxy Acid), BHA (β-hydroxy acid), and urea, which have keratin soluble effects. Third, the action of proteolytic enzymes that exfoliate by physiological action It is a product that exfoliates keratin by applying. These peeling methods exfoliate the skin first and then induce regeneration of the skin itself. Once skin has been removed to some extent, it will begin to regenerate itself. However, peeling and regenerating formulas are not suitable for sensitive or sensitive skin because peeled skin is directly exposed to all kinds of external risks until regenerated skin is raised, and it is a regeneration method after pre-filling.
상기에 기술한 각질제거 방법과는 달리 먼저 피부를 재생하여 각질이 박리되도록 하여 피부에 안전하며 효과적으로 각질을 제거하는 방식이 천연약초를 이용한 각질제거 방법의 제품이다.Unlike the exfoliation method described above, it is a product of exfoliation method using natural herbal medicine that firstly regenerates the skin to exfoliate the exfoliation, thereby safely and effectively removing the exfoliation on the skin.
독일을 비롯한 유럽에서 오랜기간 동안 안전하게 이용된 방식의 천연약초에 의한 각질제거제품은 9종의 약초분말 혼합물을 함유하는 허벌파우더(Herbal Powder)제품으로서 쇠뜨기, 세이지, 위치하젤, 마시멜로우, 창질경이, 스피룰리나, 카렌둘라, 레몬밤, 페뉴그릭을 함유하고 있다. 이 제품의 각질제거 방식은 여러 종류의 약초성분이 피부에 흡수되도록 마사지를 하여 일차적으로 혈액순환을 유도하고 동시에 피부 속에서 지속적으로 세포의 재생을 촉진시켜 3일 내지 5일 이내에 각질이 탈락되도록 유도하는 것이다.Exfoliating products by natural herbs of long-term safe use in Germany and Europe are Herbal Powder products containing a mixture of nine kinds of herbal powders, such as horsetail, sage, witch hazel, marshmallow, scabbard, It contains spirulina, calendula, lemon balm and fenugreek. The exfoliation method of this product massages various kinds of herbal ingredients to be absorbed into the skin and induces blood circulation primarily, and at the same time promotes the regeneration of cells in the skin to induce the exfoliation within 3 to 5 days. It is.
그러나. 이 천연약초에 의한 각질제거 방법은 분말로 되어있기에 사용하기 전에 용매에 혼합하여 준비를 해야 하므로 바로 사용할 수 없는 불편함이 있고, 혼합하는 용매에 따라 약초 필링 화장료의 일정한 품질이 유지되지 않기에 균일한 피부 도포가 어렵고, 흡수성 및 피부밀착감이 다르게 된다. 따라서 천연 약초 필링에 의해 효과를 얻고자 하는 각질제거 및 주름 개선, 탄력 및 미백효과가 일정하게 유지가 되지 않는 단점이 있다. But. This method of exfoliation by natural herbs has a powder, so it must be prepared by mixing in a solvent before use, which is inconvenient to use immediately, and the uniform quality of herbal peeling cosmetics is not maintained according to the solvent to be mixed. It is difficult to apply one skin, and the absorbency and skin adhesion are different. Therefore, there are disadvantages in that exfoliation and wrinkle improvement, elasticity and whitening effect which are intended to obtain effects by natural herbal peeling are not maintained constantly.
또한, 천연약초가 가지는 분말의 거친 성상과 침상구조의 성분으로 인해 피부에 적용시 피부에 상당한 자극을 주어 피부가 붉게 부어오르는 현상이 나타나고 민감한 피부를 가진 사람의 경우에는 고통으로 인해 필링을 받을 수 없는 경우도 발생하게 된다.In addition, due to the coarse properties of the powder and the components of the needle-like structure of natural herbs, the skin has a significant irritation when applied to the skin, resulting in red swelling of the skin. If not, it will also occur.
따라서, 본 발명의 목적은 천연약초 분말이 가지는 사용상의 불편함과 피부 자극에 의한 부어오름 현상을 개선하여 저자극이면서도 보다 우수한 각질제거 기능과 피부 재생에 의한 주름 개선, 탄력 및 미백 효과를 갖는 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물을 제공하는데 있다. Accordingly, an object of the present invention is to improve the discomfort and swelling caused by the skin irritation of natural herbal powders, DDS having a hypoallergenic and excellent exfoliation function and wrinkle improvement by skin regeneration, elasticity and whitening effect It is to provide a cosmetic composition containing a herbal peeling powder having a mechanism.
이와 함께, 피부 기능성 물질을 피부 진피에 효과적으로 흡수시키기 위해 관련 분야에서 다양한 기술적 시도가 이루어졌다. 대표적인 것이 기능성물질의 입자 크기를 나노화 하여 기존의 모공을 통한 흡수가 아닌 세포간극사이로 흡수시킴으로서 흡수효율을 높이는 방법과 피부에 미세한 구멍을 뚫어 그 틈을 통해 기능성 물질을 흡수시키는 MTS 시스템 등이다. 그러나 이런 방법은 기능성물질 입자를 나노화시키는 과정에서 피부와의 친밀성을 높이기 위해 별도로 리포좀 캡슐화를 시켜야 하는 추가 공정에 따른 기술적 난이도와 함께 원가부담이 발생하며, MTS의 경우 피시술자가 받는 고통을 경감하기 위해 별도의 마취 과정을 거쳐야하는 번거로운 과정이 발생하게 된다. 따라서 본 발명은 피부에 허벌파우더를 적용할 때 화장료 조성물 상에서 침상구조 성분에 흡수되었던 기능성 물질이 침상구조 성분이 진피에 임플란팅(implanting)됨으로써 별도의 과정 없이 진피 흡수를 극대화함으로써 여드름 치료, 피부 탄력, 튼살 등의 추가 기능을 제공할 수 있다는데 그 목적을 두고 있다.In addition, various technical attempts have been made in the related art to effectively absorb skin functional substances into the dermis of the skin. Representative examples are MTS systems that increase the absorption efficiency by nanoscopicizing the particle size of the functional material and absorbing it between the cell gaps, rather than through the existing pores, and absorbing the functional material through the gaps by drilling fine holes in the skin. However, this method incurs the cost burden along with the technical difficulty according to the additional process of liposome encapsulation separately to increase the intimacy with the skin in the process of nanoparticles of functional material, and in the case of MTS to reduce the pain suffered by the subject In order to create a cumbersome process that requires a separate anesthesia process. Therefore, the present invention maximizes the dermal absorption without any additional process by maximizing the absorption of dermis without any additional process by implanting the functional material was absorbed into the needle structure component on the cosmetic composition on the cosmetic composition when applying the herbal powder to the skin Its purpose is to provide additional features such as elasticity and stretch marks.
즉, 본 발명은 목적은, 천연약초 분말이 가지는 피부 자극에 의한 사용상의 불편함과 피부 자극에 의한 부어오름 현상을 개선한 화장료 조성물로서, 약초분말 혼합물인 허벌파우더(Herbal Powder)에 산탄검, 친수성 보습제, 피부재생/기능성 성분 또는 천연항염성분, 천연허브오일을 각각 소정의 비율로 첨가·함유시켜 배합함으로써 피부의 자극없이 사용이 편리하고, 피부에 안전하면서도 효과적으로 각질이 제거될 수 있도록 하여 피부 재생에 의한 주름 개선, 탄력 및 미백효과가 우수하도록 하며, 허벌파우더의 침상구조 성분이 신개념 DDS(Drug Delivery System) 메커니즘으로 작용해 기능성 성분을 피부에 효과적으로 제공하도록 침상 구조물 성분과 화장료 조성물의 배합을 조정하여 침상 구조물에의 흡수도 및 친밀도를 높인 화장료 조성물을 제공하고자 하는데 있다.That is, an object of the present invention is a cosmetic composition that improves discomfort in use due to skin irritation and swelling due to skin irritation of natural herbal powders, and a powdered herbal powder (Herbal Powder) in xanthan gum, By adding and containing a hydrophilic moisturizer, skin regeneration / functional ingredient or natural anti-inflammatory ingredient and natural herb oil in predetermined ratios, it is convenient to use without skin irritation, and it can be removed safely and effectively. Wrinkle improvement, elasticity and whitening effect by regeneration are excellent, and needle powder structure of Herbal Powder acts as a new concept DDS (Drug Delivery System) mechanism to provide functional ingredients effectively to the skin. To provide a cosmetic composition with improved absorption and intimacy to the needle-like structure. There used.
상기 목적을 달성하기 위한 본 발명의 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물은 상품으로 상용화되어 판매되고 있는 허벌파우더 10 ~ 50 중량%에 대하여 산탄검 0.1 ~ 5중량%, 친수성 보습제 0.1 ~ 20중량%, 피부재생/기능성 성분 또는 천연항염성분 0.1 ~ 5중량%, 천연허브오일 0.001 ~ 0.1% 및 나머지 정제수를 배합시켜서 액상화시킨 혼합물에 0.8 ~ 1.2MHz의 초음파를 3 ~ 5분 간 적용하여 블랜딩하여서 제조한 것을 특징으로 하며, 이러한 화장료 조성물은, 약초 필링 분말의 자극 완화 및 효능, 효과와 사용 편리성을 개선한 효과가 있으며, DDS 메커니즘 적용을 위해 초음파 블랜딩 공정을 거침으로써 침상구조 성분이 다공성 표면에 효과적으로 흡수되도록 하는 것을 특징으로 한다.Cosmetic composition containing a herbal peeling powder having a DDS mechanism of the present invention for achieving the above object is 0.1 ~ 5% by weight of xanthan gum, 0.1 ~ 5% by hydrophilic moisturizer relative to 10 to 50% by weight of the herbal powder commercially available for sale 20 to 20% by weight, skin regeneration / functional ingredient or 0.1 to 5% by weight of natural anti-inflammatory ingredient, 0.001 to 0.1% of natural herb oil and the remaining purified water were mixed and liquefied by applying 0.8 ~ 1.2MHz ultrasonic wave for 3-5 minutes Characterized in that it is prepared by blending, the cosmetic composition has the effect of reducing the stimulation and efficacy, efficacy and ease of use of herbal peeling powder, and the needle-like structure by going through the ultrasonic blending process for applying the DDS mechanism It is characterized in that it is effectively absorbed by the porous surface.
본 발명의 화장료 조성물은, 산탄검, 친수성 보습제, 피부재생/기능성 성분 또는 천연항염성분, 천연허브오일의 작용에 의하여 피부에 대한 자극과 사용이 불편한 약초 분말을 액상의 화장료 조성물로 만들어 피부에 대한 자극을 없애고, 사용에 편리성을 제공하며, 피부에 대해 안전하면서도 효과적인 각질제거와 피부 재생에 의한 주름 개선, 탄력 및 미백에 우수한 효과를 발휘하게 된다.Cosmetic composition of the present invention, by the action of xanthan gum, hydrophilic moisturizers, skin regeneration / functional ingredients or natural anti-inflammatory ingredients, natural herb oil to make a liquid cosmetic composition of the herbal powders that are irritable to the skin and inconvenient to use It eliminates irritation, provides convenience for use, and exerts an excellent effect on safe and effective exfoliation for skin and wrinkle improvement, elasticity and whitening by skin regeneration.
또한, 본 발명의 화장료 조성물에서 허벌파우더의 침상구조 분말성분은 신개념 DDS(Drug Delivery System) 메커니즘으로 기능성 성분을 피부에 직접 작용하게 하는데, 이는 약초 필링 분말 중 담수해면에서 추출한 침상구조 성분의 다공성 표면에 나노화 된 기능성 성분 또는 천연항염성분이 초음파 공정을 통해 흡수되며, 침상구조물이 마사지를 통해 피부에 임플란팅(implanting)되면서 기능성 성분 또는 천연항염성분이 삼투압에 의해 피부내에서 배출되고 진피내에 직접적으로 작용되게 함으로써 여드름 치료, 피부 탄력, 튼살 등 추가 스킨케어 기능을 효과적으로 제공하게 된다. In addition, the needle-like powder component of the herbal powder in the cosmetic composition of the present invention is a new concept of the drug delivery system (DDS) mechanism to act directly on the skin, which is a porous surface of the needle-like component extracted from the fresh sea surface of herbal peeling powder The functionalized component or natural anti-inflammatory component is nano-absorbed through the ultrasonic process, and the needle structure is implanted into the skin by massage, and the functional or natural anti-inflammatory component is released from the skin by osmotic pressure and directly into the dermis. It will effectively provide additional skincare features such as acne treatment, skin elasticity and stretch marks.
이와 같은 본 발명을 더욱 상세히 설명하면 다음과 같다. Referring to the present invention in more detail as follows.
본 발명의 약초 필링 분말의 자극 완화 및 사용 편리성을 개선한 화장료 조성물은 상품으로 상용화되어 판매되고 있는 허벌파우더 10 ~ 50 중량%에 대하여 산탄검 0.1 ~ 5중량%, 친수성 보습제 0.1 ~ 20중량%, 피부재생/기능성 성분 또는 천연항염성분 0.1 ~ 5중량%, 천연허브오일 0.001 ~ 0.1% 및 나머지 정제수를 배합시켜서 된 것으로, 상기 화장료 조성물에서, 허벌파우더는 쇠뜨기, 세이지. 위치하젤, 마시멜로우, 창질경이, 스피룰리나. 카렌둘라. 레몬밤, 페뉴그릭을 함유하며, 피부에 흡수되도록 마사지를 하면 일차적으로 혈액순환을 유도하고 동시에 피부 속에서 지속적으로 세포의 재생을 촉진시켜 3일 내지 5일 이내에 각질이 탈락되도록 유도하는 성분이며, 침상구조물의 신개념 DDS 메커니즘을 갖도록 10 ~ 50 중량%의 범위로 사용하는 것이 바람직하다.Cosmetic composition improved stimulation and ease of use of herbal peeling powder of the present invention is 0.1 to 5% by weight of xanthan gum, 0.1 to 20% by weight of hydrophilic moisturizer based on 10 to 50% by weight of the herbal powder commercially available as a product , Skin regeneration / functional ingredients or natural anti-inflammatory ingredients 0.1 to 5% by weight, natural herb oil 0.001 to 0.1% and the remaining purified water, in the cosmetic composition, the herbal powder is iron, sage. Witch hazel, marshmallows, plantain, spirulina. Calendula. It contains lemon balm and phenegrig, and when massaged to be absorbed into the skin, it induces blood circulation, and at the same time, promotes the regeneration of cells in the skin and induces exfoliation within 3 to 5 days. It is preferable to use in the range of 10 to 50% by weight to have a new concept DDS mechanism of the needle structure.
만일 10중량% 미만으로 사용할 경우에는 침상구조성분의 농도가 낮아져 효과가 저하되는 문제점이 있게 되고, 반대로 50중량%를 초과하여 사용할 경우에는 점도상승으로 피부에 적용할 경우 편리성이 떨어지는 문제점이 발생하게 되므로 상기 범위 내로 사용하는 것이 적절하다. If it is used less than 10% by weight, the concentration of the needle-like structural component is lowered, there is a problem that the effect is lowered. On the contrary, when it is used in excess of 50% by weight, the problem of inconvenience when applied to the skin due to the viscosity increase occurs It is appropriate to use within the above range.
본 발명에 사용하는 산탄검은 Xanthomonas Campestris 균을 사용하여 탄수화물을 순수배양발효하여 얻은 고분자다당류검물질을 이소프로필알콜에 정제·건조·분쇄한 것으로서 포도당, 만노스 및 글루크론산 등으로 구성된 천연혼합물질이다. 산탄검은 pH에 의한 점도 저하가 없으며 넓은 범위 내에서도 안정한 편이기에 식품을 비롯한 화장품에서 안정제, 점증제, 사용성 개선제로 사용되는 성분이며, 이는 0.1 ~ 5중량%의 범위로 사용하는 것이 바람직하다.Xantho gum used in the present invention is a natural mixed substance composed of glucose, mannose and gluconic acid, which are purified, dried and pulverized with a polysaccharide gum material obtained by pure culture fermentation of carbohydrates using Xanthomonas Campestris. Xanthan gum is a component that is used as a stabilizer, thickener, and usability improving agent in cosmetics, including food, because it does not have a viscosity decrease due to pH and is stable within a wide range, and it is preferable to use it in the range of 0.1 to 5% by weight.
여기서, 만일 0.1중량% 미만으로 사용할 경우에는 점도가 너무 낮아져 안정성이 떨어지게 되는 문제점이 있게 되고, 반대로 5중량%를 초과하여 사용할 경우에는 점도상승으로 피부에 적용할 경우 편리성이 떨어지는 문제점이 발생하게 되므로 상기 범위 내로 사용하는 것이 적절하다. Here, if it is used less than 0.1% by weight, the viscosity is too low, there is a problem that the stability is lowered, on the contrary, when used in excess of 5% by weight when the viscosity rises when applied to the skin to cause a problem of less convenience Therefore, it is appropriate to use within the above range.
본 발명에서 사용하는 친수성 보습제는 부틸렌글리콜, 아미노산, 글리세린 중에서 한 가지 이상을 사용할 수 있으며, 약초분말에 의한 피부 건조함을 방지하고, 피부재생을 도와주어 각질제거 기능을 더 향상시킬 수 있다. 전체 조성물에 대하여 0.1~20중량%의 범위로 사용하는 것이 바람직하다.Hydrophilic moisturizers used in the present invention may be used at least one of butylene glycol, amino acids, glycerin, to prevent skin dryness by herbal powders, and help skin regeneration to further improve the exfoliation function. It is preferable to use in the range of 0.1-20 weight% with respect to the whole composition.
여기서, 만일 0.1중량% 미만으로 사용할 경우에는 보습력저하로 피부에 적용할 경우 피부 건조현상이 발생되는 문제점이 있게 되고, 반대로 20중량%를 초과하여 사용할 경우에는 산탄검과의 반응으로 안정성이 저하되는 문제점이 발생하게 되므로 상기 범위 내로 사용하는 것이 적절하다. Here, if less than 0.1% by weight, when applied to the skin to reduce the moisturizing power, there is a problem that the skin dry phenomenon occurs, on the contrary, when used in excess of 20% by weight is lowered in stability by reaction with xanthan gum Since problems arise, it is appropriate to use the above range.
본 발명에서 사용하는 피부재생/기능성 성분은 아스코빌글루코사이드, 아스콜빈산 및 그 유도체 중에서 한 가지 이상을 사용할 수 있으며, 인체에서 세포 재생에 필요한 물질이나 기능을 향상시켜 주고 콜라겐 합성을 증진시켜 상처 치유 능력을 향상시켜 약초분말에 의한 피부재생을 도와주어 각질제거 기능을 더 향상시킬 수 있다. 또한 허벌파우더 침상 구조물에 의한 DDS 메커니즘에서 진피까지 안정성 있게 전달되고 흡수될 수 있도록 침상 구조물에의 흡수도와 친밀도에 초점을 맞추고, 진피 내에서의 흡수도 극대화 되도록 나노리포좀화 하며, 전체조성물에 대하여 0.1~5중량%의 범위로 사용하는 것이 바람직하다.As the skin regeneration / functional ingredient used in the present invention, one or more of ascorbyl glucoside, ascorbic acid, and derivatives thereof may be used, and wound healing may be performed by improving substances or functions necessary for cell regeneration in the human body and enhancing collagen synthesis. Enhance the ability to help skin regeneration by herbal powders can further improve the exfoliation function. In addition, it focuses on the absorption and intimacy of the needle structure so that it can be stably transmitted and absorbed from the DDS mechanism by the herbal powder needle structure to the dermis, and nanoliposomes are formed to maximize the absorption in the dermis, and 0.1 to the whole composition. It is preferable to use in the range of -5 weight%.
만일 0.1중량% 미만으로 사용할 경우에는 효과가 저하되는 문제점이 있게 되고, 반대로 5중량%를 초과하여 사용할 경우에는 활성성분 농도가 높아지며 피부 자극성이 발생되는 문제점이 발생하게 되므로 상기 범위 내로 사용하는 것이 적절하다. If it is used less than 0.1% by weight, there is a problem that the effect is reduced, on the contrary, when used in excess of 5% by weight, the active ingredient concentration increases and skin irritation occurs, so it is appropriate to use within the above range Do.
이와는 달리 여드름 케어를 위해서는 천연항염성분을 사용할 수 있으며 이는 마치현 추출물, 알테로모나스발효추출물, 분홍바늘꽃잎줄기추출물 중에서 한가지 이상을 사용할 수 있으며, 모낭 내 피지 생성 억제 및 여드름 생성 원인균 (P. Acne)에 대한 항균 및 항염효과를 제공하고 모낭 내 각질을 제거하여 모공이 막혀 피지가 모낭 내에서 정체되는 현상을 방지함으로써 여드름의 생성을 억제하고 생성된 여드름의 증상을 완화시킬 수 있다. 이는 전체 조성물에 대해 0.1 ~ 5중량%의 범위로 사용하는 것이 바람직하다. On the other hand, natural anti-inflammatory ingredients can be used for acne care, which can be used as one or more of extracts from Machi, Alteronas fermented extracts, and pink needle leaf extracts.It inhibits sebum production in hair follicles and causes acne (P. Acne) It provides antimicrobial and anti-inflammatory effects on the hair follicles and removes dead skin cells to prevent clogging of the sebum in the hair follicles can suppress the production of acne and relieve the symptoms of the resulting acne. It is preferable to use it in the range of 0.1-5 weight% with respect to the whole composition.
여기서, 만일 0.1중량% 미만으로 사용할 경우에는 효과가 저하되는 문제점이 있게 되고, 반대로 5중량%를 초과하여 사용할 경우에는 활성성분 농도가 높아지며 피부자극성이 발생되는 문제점이 발생하게 되므로 상기 범위 내로 사용하는 것이 적절하다. Here, if the use is less than 0.1% by weight, there is a problem that the effect is lowered, on the contrary, when used in excess of 5% by weight, the active ingredient concentration increases and skin irritation occurs, so use within the above range Is appropriate.
본 발명에서 사용하는 천연허브오일은 유칼립듀스, 티트리, 오렌지스윗 중에서 한가지 이상을 사용할 수 있으며 피부재생효과, 항염증, 스트레스와 긴장을 완화하여 기분전환에 도움을 주고, 무엇보다 피부에 대한 재생효과를 주어 각질제거 기능을 더 향상시킬 수 있다. 특히 티트리는 자체 항균효과로 여드름 원인균 (P. Acne) 제거에 효과적이다. 전체조성물에 대하여 0.001~0.1중량%의 범위로 사용하는 것이 바람직하다.Natural herb oil used in the present invention can be used in one or more of eucalyptus, tea tree, orange sweet and rejuvenate skin relieve effect, anti-inflammatory, relieves stress and tension, and above all for skin It can improve the function of exfoliation by regenerating effect. In particular, tea tree has its own antibacterial effect, which is effective for removing acne. It is preferable to use in the range of 0.001-0.1 weight% with respect to the whole composition.
만일 0.001중량% 미만으로 사용할 경우에는 효과가 저하되는 문제점이 있게 되고, 반대로 0.1중량%를 초과하여 사용할 경우에는 향취가 너무 강하여 개인별 취향에 맞지 않게 되는 문제점이 발생하게 되므로 상기 범위 내로 사용하는 것이 적절하다. If the amount is less than 0.001% by weight, there is a problem that the effect is lowered. On the contrary, when the amount is used in excess of 0.1% by weight, the odor is too strong to suit individual tastes. Do.
본 발명에 의하면, 기능성 성분 또는 천연항염성분이 침상구조 성분 표면의 세공에 효과적으로 흡수시키기 위해서 초음파를 통한 블랜딩 공정이 필요하다. 이는 침상구조 성분 표면의 세공은 그 크기가 나노사이즈(nano size)로써 세공 내부를 차지하고 있던 같은 크기의 공기방울이 일반적인 상태에서는 용액상의 기능성 성분 또는 천연항염성분과 세공 내에서 치환되지 못함으로써 침상구조 성분이 피부내에 임플란팅(implanting)되어도 DDS 메카니즘을 발휘하지 못하게 된다. 이를 개선하기 위해 0.8 ~ 1.2MHz 범위의 초음파를 3 ~ 5분간 적용시킴으로써 초음파에 의한 공동현상(cavitation effect)으로 기능성 성분 또는 천연 항염성분이 침상구조 성분 표면 세공내 공기입자와 효과적으로 치환되어 세공 내부에 흡수되게 된다. According to the present invention, a blending process through ultrasonic waves is required in order for the functional ingredient or natural anti-inflammatory ingredient to be effectively absorbed into the pores on the surface of the needle-like component. This is because the pore on the surface of the needle-like component is nano-sized, and the needle-like component is not substituted in the pores with the functional component or natural anti-inflammatory component in the normal state of the same size of air bubbles that occupy the inside of the pore. Implantation into the skin will not allow the DDS mechanism to be exercised. In order to improve this, by applying ultrasonic waves in the range of 0.8 to 1.2 MHz for 3 to 5 minutes, the cavitation effect of the ultrasonic waves effectively replaces the functional or natural anti-inflammatory components with air particles in the surface pores of the needle structure components. Will be absorbed.
여기서, 만일 상기와 같은 초음파 공정조건의 범위를 초과할 경우에는 DDS 메카니즘이 제대로 발휘되지 못하는 문제점이 발생하게 되므로 위와 같은 조건을 유지하는 것이 바람직하다. Here, if the range of the ultrasonic processing conditions as described above is exceeded, the DDS mechanism is not properly exhibited, so it is preferable to maintain the above conditions.
본 발명에 따른 화장료 조성물은 밀폐 앰플용기에 포장하여 외부 환경으로부터 미생물 오염등을 방지하고 저장 안정성을 높여 유통기간을 획기적으로 늘이고 1회용 용기를 사용함으로써 반복사용으로 인한 위생상의 문제발생을 방지할 수 있다.The cosmetic composition according to the present invention can be packaged in an airtight ampoule container to prevent microbial contamination from the outside environment, increase storage stability, and significantly increase the shelf life and prevent the occurrence of hygiene problems due to repeated use. have.
하기 실시예는 본 발명의 범주 내에 있는 구현 예를 더 상세히 기술하고 증명하는 것이다. 실시예는 단지 설명을 위한 것으로서 본 발명을 제한하려는 것은 아니며, 본 발명의 정신 및 범주 내에 벗어남이 없이 많은 변형이 가능하다.The following examples describe and demonstrate in more detail embodiments that are within the scope of the present invention. The examples are illustrative only and are not intended to limit the invention, and many modifications are possible without departing from the spirit and scope of the invention.
실시예 1 내지 7(비교예 1 내지 3)Examples 1 to 7 (Comparative Examples 1 to 3)
약초 분말의 자극 완화 및 사용 편리성 개선에 의한 각질제거 및 피부 세포재생에 의한 미백 효과가 우수한 화장료 조성물을 표1, 표2에, 여드름 치료용 조성물을 표3에 따라 제조하였다.이 중 실시예 1 내지 7은 DDS 메카니즘을 발휘할 수 있도록 각 성분의 혼합물을 0.8 내지 1.2MHz 범위의 초음파에 3~5분간 적용시킨 후 실험에 적용하였다.Cosmetic compositions having excellent whitening effect by exfoliation and skin cell regeneration by stimulating medicinal herbs and improving convenience of use were prepared in Tables 1 and 2, and compositions for acne treatment according to Table 3. 1 to 7 were applied to the experiment after applying the mixture of each component to the ultrasonic wave in the range of 0.8 to 1.2MHz for 3-5 minutes to exert the DDS mechanism.
표1Table 1
Figure PCTKR2009000601-appb-I000001
Figure PCTKR2009000601-appb-I000001
표 2TABLE 2
Figure PCTKR2009000601-appb-I000002
Figure PCTKR2009000601-appb-I000002
표 3TABLE 3
Figure PCTKR2009000601-appb-I000003
Figure PCTKR2009000601-appb-I000003
실험예 1 : 사용 편리성Experimental Example 1 Usability
비교예 1 내지 2와 실시예 1 에서 4를 대상으로 사용성 편리성을 평가하였다. 즉, 3개의 평가 샘플을 1세트[(비교예1, 실시예1, 실시예2) 혹은 (비교예2, 실시예3, 실시예4)]로 하여 총 20명에게 관능 평가를 실시하고 그 결과를 표4에 나타내었다.Usability was evaluated for Comparative Examples 1 to 2 and Examples 1 to 4. That is, the sensory evaluation was performed on a total of 20 people using three evaluation samples as one set ((Comparative Example 1, Example 1, Example 2) or (Comparative Example 2, Example 3, Example 4)]. The results are shown in Table 4.
<평가기준><Evaluation Criteria>
1: 매우 나쁨, 2: 나쁨, 3: 약간 나쁨, 4: 보통, 5: 약간 좋음, 6: 좋음, 7: 매우 좋음1: very bad, 2: bad, 3: slightly worse, 4: moderate, 5: slightly better, 6: good, 7: very good
표4Table 4
Figure PCTKR2009000601-appb-I000004
Figure PCTKR2009000601-appb-I000004
상기 표4에 나타난 바와 같이, 실시예 1 내지 실시예 4의 피부도포시 용이성, 흡수성, 피부밀착성이 우수하여 사용 편리성이 개선된 것으로 확인되었다.As shown in Table 4, it was confirmed that the ease of use, absorbency, and skin adhesion during application of the skin of Examples 1 to 4 were improved.
실험예 2: 피부자극성Experimental Example 2: Skin Irritant
비교예 1 내지 2와 실시예 1 에서 4를 대상으로 피부 자극성을 평가하였다. 즉, 3개의 평가 샘플을 1세트[(비교예1, 실시예1, 실시예2) 혹은 (비교예2, 실시예3, 실시예4)]로 하여 총 20명에게 관능 평가를 실시하고 그 결과를 표 5에 나타내었다.Skin irritation was evaluated in Comparative Examples 1 to 2 and Examples 1 to 4. That is, the sensory evaluation was performed on a total of 20 people using three evaluation samples as one set ((Comparative Example 1, Example 1, Example 2) or (Comparative Example 2, Example 3, Example 4)]. The results are shown in Table 5.
<평가기준><Evaluation Criteria>
1: 심한 자극, 2: 자극 있음, 3: 보통의 자극, 4: 약간의 자극. 5: 자극 없음1: severe stimulation, 2: with stimulation, 3: moderate stimulation, 4: slight stimulation. 5: no irritation
표5Table 5
Figure PCTKR2009000601-appb-I000005
Figure PCTKR2009000601-appb-I000005
상기 표5에 나타난 바와 같이. 실시예 1 내지 실시예 4의 피부자극성에 대한 값이 비교예 1 내지 2보다 더 '자극없음'의 값에 가까워 피부자극성이 개선된 것으로 확인할 수 있었다.As shown in Table 5 above. The skin irritation of Examples 1 to 4 was closer to the value of 'no irritation' than that of Comparative Examples 1 and 2, indicating that the skin irritation was improved.
실험예 3 : 각질제거 및 세포재생에 의한 피부색 개선효과Experimental Example 3 skin color improvement effect by exfoliation and cell regeneration
상기 비교예 1 내지 2와 실시예 1 내지 4를 대상으로 피부에 흡수시키고 5일 후에 피부색의 개선효과를 측정하였다. 그 결과를 다음 표 6에 나타내었다. Absorption to the skin of Comparative Examples 1 to 2 and Examples 1 to 4 was measured 5 days after the improvement of skin color. The results are shown in Table 6 below.
20세~50세의 여성 10명을 대상으로 안면 왼쪽 부분에는 비교예 1 또는 비교예 2를, 안면 오른쪽부분에는 실시예 1 또는 실시예 3의 제품을 각각 1제품씩 도포한 후 각질이 탈락되고 피부가 재생되어 완료되는 5일이 경과한 시점에 얼굴 좌우 양쪽의 피부를 멜라닌-에리데마 인덱스 메터(melanin-erythema index meter)로 멜라닌지수를 측정하여 제품 사용 전, 후에 대한 결과값을 나타냈다.For 10 women aged 20 to 50 years, each of the products of Example 1 or Example 3 was applied to the left side of the face, and each product of Example 1 or Example 3 was applied to the right side of the face, and then the dead skin was removed. 5 days after the skin was regenerated and completed, the melanin index was measured by using a melanin-erythema index meter on both sides of the face, and the results were shown before and after using the product.
표6Table 6
Figure PCTKR2009000601-appb-I000006
Figure PCTKR2009000601-appb-I000006
*감소율 = 사용전 멜라닌 지수-사용후 멜라닌 지수/사용전 멜라닌 지수×100* Reduction ratio = melanin index before use-melanin index after use / melanin index before use × 100
표6에 나타난 바와 같이 실시예 1 내지 3의 화장료를 사용했을때 비교예 1 내지 2에 비해 멜라닌 지수의 감소율이 더 높음을 나타낸다. 따라서, 본 발명에 따른 실시예 1 내지 3의 화장료는 효과적으로 각질이 제거될 수 있도록 하고 피부세포 재생에 의한 피부색 개선효과를 나타낼 수 있음을 알 수 있다.As shown in Table 6, when the cosmetics of Examples 1 to 3 are used, the reduction rate of the melanin index is higher than that of Comparative Examples 1 to 2. Therefore, it can be seen that the cosmetics of Examples 1 to 3 according to the present invention can effectively remove dead skin cells and exhibit skin color improvement effect by skin cell regeneration.
실험예 4: 여드름 치료효과Experimental Example 4: Acne Treatment Effect
상기 비교예 5, 실시예 6과 실시예 7을 대상으로 여드름 치료효과를 측정하였다. 20~50세의 여성 20명을 대상으로 안면 전면부를 촬영한 후, 사진으로 인식되는 염증 포인트를 좌, 우측 안면으로 구분하여 개수를 센 후 기록한다. 여성 10명에게는 좌측 안면에 비교예 5, 우측 안면에 실시예 6을, 나머지 여성 10명에게는 좌측 안면에 비교예 5, 우측 안면에 실시예 7 제품을 각각 1개씩 도포한다. 각질이 탈락되고 피부가 재생되어 완료되는 5일이 경과한 시점에 피실험자의 안면 전면부를 촬영한 후 사진으로 인식되는 염증 포인트를 좌, 우측 안면으로 구분하여 개수를 센 후 기록한다. 다음 표 7에 이에 대한 결과를 나타내었다.Acne treatment effect was measured in Comparative Example 5, Example 6 and Example 7. After photographing the front face of 20 women aged 20 to 50 years, count the number of inflammation points that are recognized as photographs by dividing them into left and right faces. 10 females were coated with Comparative Example 5 on the left face and Example 6 on the right face, and 10 females were coated with one Example 7 product on the left face and Comparative Example 5 on the right face. Five days after the dead skin is removed and the skin is regenerated, the front part of the subject's face is photographed, and the number of inflammation points recognized as a photograph is divided into left and right faces, and the number is recorded. Table 7 shows the results.
표 7TABLE 7
Figure PCTKR2009000601-appb-I000007
Figure PCTKR2009000601-appb-I000007
*감소율 = (사용전 염증 포인트 - 사용후 염증 포인트)/사용전 염증포인트× 100(%)* Reduction rate = (Inflammation point before use-Inflammation point after use) / Inflammation point before use × 100 (%)
표7에 나타난 바와 같이 실시예 6내지 실시예 7의 제품을 사용 했을때 비교예 5에 비해 여드름 감소율이 더 높음을 알 수 있다. 따라서, 본 발명에 따른 실시예 6 내지 실시예 7의 화장료는 효과적으로 여드름을 제거하고 생성을 완화하는 효과를 나타낼 수 있음을 알 수 있다.As shown in Table 7, it can be seen that the acne reduction rate is higher than that of Comparative Example 5 when the products of Examples 6 to 7 are used. Therefore, it can be seen that the cosmetics of Examples 6 to 7 according to the present invention can effectively remove acne and alleviate the production.
본 발명의 화장료 조성물은, 피부에 대한 자극을 없애고, 사용에 편리성을 제공하며, 피부에 대해 안전하면서도 효과적인 각질제거와 피부 재생에 의한 주름 개선, 탄력 및 미백에 우수하다.The cosmetic composition of the present invention eliminates irritation to the skin, provides convenience for use, and is excellent for wrinkle improvement, elasticity and whitening by safe and effective exfoliation and skin regeneration for the skin.
또한, 본 발명의 화장료 조성물은 여드름 치료, 피부 탄력, 튼살 등 추가 스킨케어 기능을 효과적으로 제공한다. In addition, the cosmetic composition of the present invention effectively provides additional skin care functions such as acne treatment, skin elasticity, stretch marks.

Claims (5)

  1. 상품으로 상용화되어 판매되고 있는 허벌파우더 10 ~ 50 중량%에 대하여 산탄검 0.1 ~ 5중량%, 친수성 보습제 0.1 ~ 20중량%, 피부재생/기능성 성분 또는 천연항염성분 0.1 ~ 5중량%, 천연허브오일 0.001 ~ 0.1% 및 나머지 정제수를 배합시켜서 된 액상 혼합물에 0.8 ~ 1.2MHz의 초음파를 3 ~ 5분 간 적용하여 블랜딩하여서 제조한 것을 특징으로 하는 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물.0.1 to 5% by weight of xanthan gum, 0.1 to 20% by weight of hydrophilic moisturizer, 0.1 to 5% by weight of skin regeneration / functional or natural anti-inflammatory ingredients, and natural herb oil A cosmetic composition containing a herbal peeling powder having a DDS mechanism, characterized in that the mixture is prepared by applying an ultrasonic wave of 0.8 to 1.2 MHz for 3 to 5 minutes to a liquid mixture obtained by mixing 0.001 to 0.1% and the remaining purified water.
  2. 제 1항에 있어서, 상기 친수성 보습제는 부틸렌글리콜, 아미노산, 글리세린으로 이루어진 군으로부터 적어도 하나를 선택하여서 되는 것을 특징으로 하는 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물.The cosmetic composition containing a herbal peeling powder having a DDS mechanism according to claim 1, wherein the hydrophilic moisturizing agent is selected from at least one selected from the group consisting of butylene glycol, amino acids and glycerin.
  3. 제 1항에 있어서, 상기 피부재생/기능성 성분은 아스코빌글루코사이드, 아스콜빈산 및 그 유도체로 이루어진 군으로부터 적어도 하나를 선택하여서 된 것을 특징으로 하는 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물.The cosmetic composition comprising a herbal peeling powder having a DDS mechanism according to claim 1, wherein the skin regeneration / functional ingredient is selected from at least one selected from the group consisting of ascorbyl glucoside, ascorbic acid and derivatives thereof.
  4. 제 1항에 있어서, 상기 천연항염성분은 마치현 추출물, 알테로모나스발효추출물, 분홍바늘꽃잎줄기추출물로 이루어진 군으로부터 적어도 하나를 선택하여서 되는 것을 특징으로 하는 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물.According to claim 1, wherein the natural anti-inflammatory ingredient is a cosmetic composition containing a herbal peeling powder having a DDS mechanism, characterized in that at least one selected from the group consisting of Portulaca extract, Alteromonas fermentation extract, pink needle leaf extract Composition.
  5. 제1항에 있어서, 상기 천연허브오일은 유칼립듀스, 티트리. 오렌지스윗으로 이루어진 군으로부터 적어도 하나를 선택하여서 된 것을 특징으로 하는 DDS 메커니즘을 갖는 약초 필링 분말을 함유하는 화장료 조성물.According to claim 1, The natural herb oil is eucalyptus, tea tree. Cosmetic composition containing a herbal peeling powder having a DDS mechanism, characterized in that at least one selected from the group consisting of orange sweets.
PCT/KR2009/000601 2009-02-10 2009-02-10 Cosmetic composition containing herbal peeling powder having dds mechanism WO2010093065A1 (en)

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WO2018065545A1 (en) * 2016-10-05 2018-04-12 Pierre Fabre Dermo-Cosmetique Use of 6-o-(c8-c20 alkyl ester) of 1-o-(c1-c6 alkyl)-ss-d-glucoside as an agent for protecting the skin

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