WO2010086724A2 - Crème à base de plantes et compositions de lotion et procédés de préparations associés - Google Patents

Crème à base de plantes et compositions de lotion et procédés de préparations associés Download PDF

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Publication number
WO2010086724A2
WO2010086724A2 PCT/IB2010/000169 IB2010000169W WO2010086724A2 WO 2010086724 A2 WO2010086724 A2 WO 2010086724A2 IB 2010000169 W IB2010000169 W IB 2010000169W WO 2010086724 A2 WO2010086724 A2 WO 2010086724A2
Authority
WO
WIPO (PCT)
Prior art keywords
composition according
herbs
extract
lotion
cream
Prior art date
Application number
PCT/IB2010/000169
Other languages
English (en)
Other versions
WO2010086724A3 (fr
Inventor
Ramesh Surianarayanan
Uddagiri Venkanna Babu
Chandrika Mahendra
Original Assignee
Himalaya Global Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Himalaya Global Holdings Limited filed Critical Himalaya Global Holdings Limited
Publication of WO2010086724A2 publication Critical patent/WO2010086724A2/fr
Publication of WO2010086724A3 publication Critical patent/WO2010086724A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • This invention in general relates to a herbal body cream and lotion composition and methods of preparation thereof.
  • the present invention provides a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein the extract is prepared employing a super critical fluid extraction or water extraction.
  • Body cream and lotions generally contain ingredients like liquid paraffin that is petroleum based, and ethoxylated emulsifiers that are made using ethylene oxide and extract of herbs in case of herbal products that are grown by regular methods using pesticides and using harsh preservatives.
  • ethoxylated emulsifiers is seen more and more as a disadvantage.
  • composition comprising natural wax as an emulsifier, extract of Curcuma and the gum of Acacia or Colohonium or shorea. This is combined with essential oil and petroleum jelly.
  • US Patent no. 6544530 by Friedman et al. discloses a topically applicable oil in glycerine composition.
  • the composition comprising vegetable oil, essential oil and emulsifier.
  • the emulsifier is of vegetable origin.
  • the composition is alcohol free.
  • US patent no. 6368639B1 by Farooqi discloses a herbal skin care composition comprising of bees wax, stearic acid, glycerol mbnostearate, olive oil, aloe gel, glycerine , triethanolamine, parabens, propylene glycol, essential oils, sandal wood oil, and rose water. The process for the preparation of composition is also disclosed. Summary of the Invention
  • It is a principal object of the present invention to provide a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said composition is devoid of any chemical contaminations.
  • It is another object of the present invention to provide a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said composition is the purest and provides superior skin benefits.
  • It is yet another object of the present invention to provide a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said compositions are made using emulsifiers that are made from natural ingredients and are not ethoxylates, with certified organic ingredient as actives and preservatives that are mild example Sorbates, and enzymes.
  • the object is to provide a method of preparing a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said method is devoid of using any solvent.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein the extract is prepared employing a super critical fluid extraction or water extraction.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein the extract of herbs is obtained from a blend of herbs selected from Glycyrrhiza glabra, Asparagus racemosus, Tinospora cordifolia, Sida cordifolia, Camellia sinensis or various combinations thereof.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein the blend is used in the range of 0.0001% to 0.5%. Preferably the blend is used in the range of 0.0001 % to 0.0005%.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein the organic essential oils is used in the range of 0.01% to 5%.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said composition is formulated in lotion and cream formulation.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein lotion is Nourishing face moisturising lotion, Revitalizing hand and body lotion.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein cream is Nourishing Night cream.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein the Revitalizing hand and body lotion comprising a herbal blend extract of herbs Glycyrrhiza glabra, Asparagus racemosus, Tinospora cordifolia, Sida cordifolia and essential oils selected from Vetiveria zizanoides, Rosmarinus officinalis, Lavandula latifolia, Syzygium aromaticum, Abelmoschus moschatus and in combination thereof along with pharmaceutically acceptable excipients.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein Nourishing Night cream comprising herbal extract of Camellia sinensis and essentials oils selected from Prunus amygdalus, Vetiveria zizanoides, Cinnamomum zeylanicum, Abelmoschus moschatus, Rosmarinus officinalis, Origanum Majorana, Pogostemon cablin and in combination thereof along with pharmaceutically acceptable excipients.
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said composition is prepared by the process comprising blending the organically certified herbs and extracting the resultant herbs employing super critical fluid extraction (SCFE), mixing the resultant extract blend with organic essential oils and mixing pharmaceutically acceptable excipients.
  • SCFE super critical fluid extraction
  • a herbal cream or lotion composition comprising extracts of organically certified herbs, organic essential oils along with pharmaceutically acceptable excipients, wherein said composition is prepared by the process comprising blending the organically certified herbs and extracting the resultant herbs employing percolation or soxhlation using water, mixing the resultant extract of blend with organic essential oils and mixing pharmaceutically acceptable excipients.
  • the present invention is about creams and lotions that are made using emulsifiers that are made from natural ingredients and are not ethoxylates, with certified organic ingredient as actives and preservatives that are mild example Sorbates, and enzymes.
  • the present invention describes the preparation of body creams such as nourishing night cream, anti blemish cream, anti acne cream, age-defying cream, under eye cream, foot care cream and body lotions such as face moisturizing lotion, revitalizing hand and body lotion using organic bees wax, organic vegetable oils, organic herbal actives along with non-ethoxylated emulsifiers and other components for the various skin benefits.
  • excipients used herein according to the present invention are selected from water, emollients, foaming agent, preservative, thickener or viscosity enhancer, fixative, vegetable oil and antioxidant.
  • the essential oils used herein according to present invention is selected from Prunus amygdalus, Vetiveria zizanoides, Cinnamomum zeylanicum, Coriandrum sativum, Lavandula latifolia, Syzygium aromaticum, Abelmoschus moschatus, Rosmarinus officinalis, Origanum Majorana, Pogostemon cablin or a combination thereof.
  • organic essential oils are used herein obtained by cold press method.
  • Phase F to the main vessel at less than 4O 0 C.
  • the dried material of Glycyrrhiza glabra roots was pulverized to coarse
  • the dried material of Tinospora cordifolia stem was pulverized to coarse powder and about 25 Kg of powdered material was placed in a SCF extractor at the temperature of 40-50C at high pressure of 280-320 bar using carbon dioxide as super critical fluid for extraction upto 4 to 6 hours and then the extract was collected in the collection vessel and evaporated at room temperature to remove any further residues of carbon dioxide.
  • the extract thus obtained was free from any solvent residues and in highest pure form.
  • the dried material of Sida cordifolia roots was pulverized to coarse powder and about 25 Kg of powdered material was placed in a SCF extractor at the temperature of 40-50C at high pressure of 280-320 bar using carbon dioxide as super critical fluid for extraction upto 4 to 6 hours and then the extract was collected in the collection vessel and evaporated at room temperature to remove any further residues of carbon dioxide.
  • the extract thus obtained was free from any solvent residues and in highest pure form.
  • Example 1 Preparation of extract from herbal blend by Super Critical Fluid Extraction
  • the shade dried material of herbal blend of Glycyrrhiza glabra roots and/or Asparagus racemosus roots and /or Tinospora cordifolia stem and/or Sida cordifolia roots in the ratio of 1 : 1 : 1 : 1 respectively was pulverized to coarse powder and about 100 Kg of powdered herbal blend was placed in a SCF extractor at the temperature of 40-50C at high pressure of 300-350 bar using carbon dioxide as super critical fluid for extraction upto 4 to 6 hours and then the extract was collected in the collection vessel and evaporated at room temperature to remove any further residues of carbon dioxide. The extract thus obtained was free from any solvent residues and in highest pure form.
  • the coarse powdered dried roots of Asparagus racemosus were subjected to hot-soxhlation by placing 10 Kg of material in soxhlator using water as solvent of extraction at refluxing temperature and recycled the process until extraction is completed, then plant extracts were filtered and concentrated to dryness on rotatory evaporator or on steam bath at optimum temperature.
  • the herbal material was also placed in percolator and extracted with water at room temperature for 24 h to 48 h., then plant extract was filtered and concentrated to dryness on rotatory evaporator or on steam bath at optimum temperature and under reduced pressure .
  • Example 14 Preparation of aqueous extract from Tinospora cordifolia stem by hot- soxhlation / cold percolation method:
  • the coarse powdered dried roots of Tinospora cordifolia stem were subjected to hot-soxhlation by placing 10 Kg of material in soxhlator using water as solvent of extraction at refluxing temperature and recycled the process until extraction is completed, then plant extracts were filtered and concentrated to dryness on rotatory evaporator or on steam bath at optimum temperature.
  • the herbal material was also placed in percolator and extracted with water at room temperature for 24 h to 48 h., then plant extract was filtered and concentrated to dryness on rotatory evaporator or on steam bath at optimum temperature and under reduced pressure .
  • Preparation of aqueous extract from Sida cordi folia roots by hot-soxhlation / cold percolation method The coarse powdered dried roots of Sida cordifolia roots were subjected to hot-soxhlation by placing 10 Kg of material in soxhlator using water as solvent of extraction at refluxing temperature and recycled the process until extraction is completed, then plant extracts were filtered and concentrated to dryness on rotatory evaporator or on steam bath at optimum temperature. The herbal material was also placed in percolator and extracted with water at room temperature for 24 h to 48 h., then plant extract was filtered and concentrated to dryness on rotatory evaporator or on steam bath at optimum temperature and under reduced pressure .
  • Example 16 Preparation of extract from herbal blend by aqueous Extraction The shade dried material of herbal blend of Glycyrrhiza glabra roots and/or
  • Example- 19 A clinical study to evaluate the moisturizing efficacy of Revitalizing Hand and Body Lotion on healthy human Volunteers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La présente invention concerne une crème à base de plantes ou une composition de lotion comprenant des extraits d'huiles essentielles biologiques provenant de plantes d'origine biologique certifiée ainsi que des excipients pharmaceutiquement acceptables, l'extrait étant préparé en utilisant une extraction par fluide supercritique ou l'extraction à l'eau
PCT/IB2010/000169 2009-01-30 2010-01-30 Crème à base de plantes et compositions de lotion et procédés de préparations associés WO2010086724A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN200/DEL/2009 2009-01-30
IN200DE2009 2009-01-30

Publications (2)

Publication Number Publication Date
WO2010086724A2 true WO2010086724A2 (fr) 2010-08-05
WO2010086724A3 WO2010086724A3 (fr) 2010-09-30

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014197427A2 (fr) 2013-06-03 2014-12-11 R. J. Reynolds Tobacco Company Compositions cosmétiques comprenant un composant dérivé de graines de tabac

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081675A1 (en) * 2001-03-02 2004-04-29 Corinna Wirth Cosmetic formulations containing flavonoid derivatives
US20060134095A1 (en) * 2003-01-27 2006-06-22 Shinobu Ito Antioxidative composition and composition for external use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081675A1 (en) * 2001-03-02 2004-04-29 Corinna Wirth Cosmetic formulations containing flavonoid derivatives
US20060134095A1 (en) * 2003-01-27 2006-06-22 Shinobu Ito Antioxidative composition and composition for external use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: 'Flowers by Botanical Names' FLOWERS OF INDIA, [Online] 19 December 2008, Retrieved from the Internet: <URL:http://replay.waybackmachine.org/20081219194618/http://www.flowersofindia.net/botanical.html> [retrieved on 2010-06-30] *
KAPOOR: 'Herbal Cosmetics for Skin and Hair Care' NATURAL PRODUCT RADIANCE vol. 4, no. 4, July 2005, pages 306 - 314 *
'THERANEEM and THERAVEDA products.' INGREDIENTS GLOSSARIES, [Online] 17 June 2006, pages 1 - 5 AND 8-9 Retrieved from the Internet: <URL:http://web.archive.org/web/20060617*/www.organixsouth.com> [retrieved on 2010-06-29] *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014197427A2 (fr) 2013-06-03 2014-12-11 R. J. Reynolds Tobacco Company Compositions cosmétiques comprenant un composant dérivé de graines de tabac
US10639269B2 (en) 2013-06-03 2020-05-05 R.J. Reynolds Tobacco Company Cosmetic compositions comprising tobacco seed-derived component

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Publication number Publication date
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