WO2010085119A3 - 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법 - Google Patents

방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법 Download PDF

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Publication number
WO2010085119A3
WO2010085119A3 PCT/KR2010/000430 KR2010000430W WO2010085119A3 WO 2010085119 A3 WO2010085119 A3 WO 2010085119A3 KR 2010000430 W KR2010000430 W KR 2010000430W WO 2010085119 A3 WO2010085119 A3 WO 2010085119A3
Authority
WO
WIPO (PCT)
Prior art keywords
beta
glucan
production method
biological tissue
based scaffold
Prior art date
Application number
PCT/KR2010/000430
Other languages
English (en)
French (fr)
Other versions
WO2010085119A2 (ko
Inventor
송성기
장용만
전인호
고상진
전정란
전계택
임윤목
권희정
Original Assignee
주식회사 큐젠바이오텍
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 큐젠바이오텍 filed Critical 주식회사 큐젠바이오텍
Priority to US13/144,851 priority Critical patent/US8592574B2/en
Priority to CN201080005258.0A priority patent/CN102292113B/zh
Priority to JP2011547784A priority patent/JP5474094B2/ja
Priority claimed from KR1020100005912A external-priority patent/KR101158776B1/ko
Publication of WO2010085119A2 publication Critical patent/WO2010085119A2/ko
Publication of WO2010085119A3 publication Critical patent/WO2010085119A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법에 관한 것이다. 본 발명에 따른 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체의 제조방법은, 베타-글루칸 수용액을 캐스팅한 후 방사선을 조사하여 가교반응을 수행하여 겔 또는 고체 형태의 지지체를 형성함으로써, 세포부착을 용이하게 하고, 줄기세포의 성장 및 분화에 효과적인 생체모방형 환경을 용이하게 구현할 수 있다. 따라서, 본 발명에 따른 베타-글루칸 기반 지지체는 조직 재생용, 세포 배양용, 성형용 충전제, 생체조직 빈공간용 충전제, 성형 보형물, 성형 보정물, 세포 이식용 및 약물전달용으로 유용하게 사용될 수 있다.
PCT/KR2010/000430 2009-01-22 2010-01-22 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법 WO2010085119A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US13/144,851 US8592574B2 (en) 2009-01-22 2010-01-22 Beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and production method therefor
CN201080005258.0A CN102292113B (zh) 2009-01-22 2010-01-22 通过辐射融合技术制造的用于生物组织工程的β-葡聚糖基支架及其制造方法
JP2011547784A JP5474094B2 (ja) 2009-01-22 2010-01-22 放射線融合技術を用いた生体組織工学用β−グルカンベースの支持体およびその製造方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20090005343 2009-01-22
KR10-2009-0005343 2009-01-22
KR1020100005912A KR101158776B1 (ko) 2009-01-22 2010-01-22 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법
KR10-2010-0005912 2010-01-22

Publications (2)

Publication Number Publication Date
WO2010085119A2 WO2010085119A2 (ko) 2010-07-29
WO2010085119A3 true WO2010085119A3 (ko) 2010-12-09

Family

ID=42356346

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/000430 WO2010085119A2 (ko) 2009-01-22 2010-01-22 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법

Country Status (1)

Country Link
WO (1) WO2010085119A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115094032A (zh) * 2022-08-23 2022-09-23 深圳市茵冠生物科技有限公司 一种牙髓间充质干细胞培养方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688775A (en) * 1991-10-15 1997-11-18 Fmc Corporation β-1,3-glucan polysaccharides, compositions, and their preparation and uses
US20030144127A1 (en) * 1999-12-28 2003-07-31 Eva Berggren Manufacture of improved support matrices
US6723429B2 (en) * 1998-08-28 2004-04-20 Celanese Ventures Gmbh Method for preparing smooth-surface spherical microparticles completely or partially made of at least one water-insoluble linear polysaccharide and microparticles produced according to this method
US20040209360A1 (en) * 2003-04-18 2004-10-21 Keith Steven C. PVA-based polymer coating for cell culture
KR20070102589A (ko) * 2005-02-02 2007-10-18 엥겔하드 리옹 에스.에이. 세포 배양을 위한 지지 장치

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688775A (en) * 1991-10-15 1997-11-18 Fmc Corporation β-1,3-glucan polysaccharides, compositions, and their preparation and uses
US6723429B2 (en) * 1998-08-28 2004-04-20 Celanese Ventures Gmbh Method for preparing smooth-surface spherical microparticles completely or partially made of at least one water-insoluble linear polysaccharide and microparticles produced according to this method
US20030144127A1 (en) * 1999-12-28 2003-07-31 Eva Berggren Manufacture of improved support matrices
US20040209360A1 (en) * 2003-04-18 2004-10-21 Keith Steven C. PVA-based polymer coating for cell culture
KR20070102589A (ko) * 2005-02-02 2007-10-18 엥겔하드 리옹 에스.에이. 세포 배양을 위한 지지 장치

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MICHALEK M. ET AL, JOURNAL OF LEUKOCYTE BIOLOGY, vol. 64, September 1998 (1998-09-01), pages 337 - 344 *

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