WO2010074460A3 - 리파아제 저해제의 부작용 개선을 위한 신규한 약제학적 조성물 - Google Patents

리파아제 저해제의 부작용 개선을 위한 신규한 약제학적 조성물 Download PDF

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Publication number
WO2010074460A3
WO2010074460A3 PCT/KR2009/007614 KR2009007614W WO2010074460A3 WO 2010074460 A3 WO2010074460 A3 WO 2010074460A3 KR 2009007614 W KR2009007614 W KR 2009007614W WO 2010074460 A3 WO2010074460 A3 WO 2010074460A3
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WO
WIPO (PCT)
Prior art keywords
side effects
lipase inhibitor
pharmaceutical composition
novel pharmaceutical
ameliorating
Prior art date
Application number
PCT/KR2009/007614
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English (en)
French (fr)
Other versions
WO2010074460A2 (ko
Inventor
김선경
이수경
기민효
Original Assignee
주식회사종근당
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 주식회사종근당 filed Critical 주식회사종근당
Publication of WO2010074460A2 publication Critical patent/WO2010074460A2/ko
Publication of WO2010074460A3 publication Critical patent/WO2010074460A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

본 발명은 리파아제 저해제 약물의 부작용을 개선시키기 위한 신규한 약제학적 조성물에 관한 것으로서, 보다 구체적으로 본 발명은 약제학적으로 허용 가능한 폴리알킬렌옥사이드계열의 양친매성 중합체 및 수용성 점증제를 포함하는 리파아제 저해제의 부작용 개선용 약제학적 조성물에 관한 것이다. 본 발명에 의하여 리파아제 저해제의 섭취로 인한 유상반점변 또는 지방변 배설 등의 부작용을 현저히 개선할 수 있다.
PCT/KR2009/007614 2008-12-24 2009-12-18 리파아제 저해제의 부작용 개선을 위한 신규한 약제학적 조성물 WO2010074460A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020080133905A KR20100075260A (ko) 2008-12-24 2008-12-24 리파아제 저해제의 부작용 개선을 위한 신규한 약제학적 조성물
KR10-2008-0133905 2008-12-24

Publications (2)

Publication Number Publication Date
WO2010074460A2 WO2010074460A2 (ko) 2010-07-01
WO2010074460A3 true WO2010074460A3 (ko) 2010-09-23

Family

ID=42288262

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/007614 WO2010074460A2 (ko) 2008-12-24 2009-12-18 리파아제 저해제의 부작용 개선을 위한 신규한 약제학적 조성물

Country Status (2)

Country Link
KR (1) KR20100075260A (ko)
WO (1) WO2010074460A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140112747A (ko) * 2013-03-14 2014-09-24 연세대학교 산학협력단 리파아제 저해제의 용출율이 증진되고 부작용이 감소된 약학적 제제 및 그의 제조방법
CN104971051A (zh) * 2014-04-11 2015-10-14 刘小斌 一种赛利司他片及制备方法
CN114642680A (zh) * 2020-12-17 2022-06-21 海洋资源股份有限公司 用于减重的组合物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251421B1 (en) * 2000-09-25 2001-06-26 Sarfaraz K. Niazi Pharmaceutical composition containing psyllium fiber and a lipase inhibitor
US20030232077A1 (en) * 1998-09-08 2003-12-18 Smithkline Beecham Corporation Lipstatin derivative - soluble fiber tablets
US20040175420A1 (en) * 1999-09-13 2004-09-09 De Smidt Passchier Christiaan Pharmaceutical compositions containing lipase inhibitors
WO2007123338A1 (en) * 2006-04-20 2007-11-01 Amorepacific Corporation Pharmaceutical composition comprising lipase inhibitor and lipophilic oil absorbent and oral formulation prepared therefrom

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232077A1 (en) * 1998-09-08 2003-12-18 Smithkline Beecham Corporation Lipstatin derivative - soluble fiber tablets
US20040175420A1 (en) * 1999-09-13 2004-09-09 De Smidt Passchier Christiaan Pharmaceutical compositions containing lipase inhibitors
US6251421B1 (en) * 2000-09-25 2001-06-26 Sarfaraz K. Niazi Pharmaceutical composition containing psyllium fiber and a lipase inhibitor
WO2007123338A1 (en) * 2006-04-20 2007-11-01 Amorepacific Corporation Pharmaceutical composition comprising lipase inhibitor and lipophilic oil absorbent and oral formulation prepared therefrom

Also Published As

Publication number Publication date
KR20100075260A (ko) 2010-07-02
WO2010074460A2 (ko) 2010-07-01

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