WO2010046929A3 - Novel polymorphic forms of temazepam and processes for preparing the same - Google Patents

Novel polymorphic forms of temazepam and processes for preparing the same Download PDF

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Publication number
WO2010046929A3
WO2010046929A3 PCT/IN2009/000589 IN2009000589W WO2010046929A3 WO 2010046929 A3 WO2010046929 A3 WO 2010046929A3 IN 2009000589 W IN2009000589 W IN 2009000589W WO 2010046929 A3 WO2010046929 A3 WO 2010046929A3
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WO
WIPO (PCT)
Prior art keywords
polymorphic forms
temazepam
processes
preparing
same
Prior art date
Application number
PCT/IN2009/000589
Other languages
French (fr)
Other versions
WO2010046929A2 (en
Inventor
Ramakoteswara Rao Jetti
Nageswara Rao Karusala
Radha Krishna Singamsetty
Asha Rani Gorantla
Madhavi Jonnalagadda
Chetan Kanaiyalal Raval
Lakshmana Rao Namburu
Debashish Datta
Original Assignee
Matrix Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrix Laboratories Limited filed Critical Matrix Laboratories Limited
Publication of WO2010046929A2 publication Critical patent/WO2010046929A2/en
Publication of WO2010046929A3 publication Critical patent/WO2010046929A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed herein are novel crystalline polymorphic forms Form I, Form II, Form III, Form IV, Form V, Form VI, Form VII, Form VIII, Form IX, Form X and amorphous form of temazepam characterized by X-ray powder diffraction patterns, DSC, TGA and IR. In addition, the invention describes processes for the preparation of the various polymorphic forms.
PCT/IN2009/000589 2008-10-17 2009-10-16 Novel polymorphic forms of temazepam and processes for preparing the same WO2010046929A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2554CH2008 2008-10-17
IN2554/CHE/2008 2008-10-17

Publications (2)

Publication Number Publication Date
WO2010046929A2 WO2010046929A2 (en) 2010-04-29
WO2010046929A3 true WO2010046929A3 (en) 2011-01-27

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ID=42119786

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000589 WO2010046929A2 (en) 2008-10-17 2009-10-16 Novel polymorphic forms of temazepam and processes for preparing the same

Country Status (1)

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WO (1) WO2010046929A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296249A (en) * 1963-06-04 1967-01-03 American Home Prod 5-monocyclic aryl-1, 3-dihydro-2h-1, 4-benzodiazepin-2-ones
US4412952A (en) * 1982-04-30 1983-11-01 Sandoz, Inc. Process for 3-hydroxy benzodiazepinones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296249A (en) * 1963-06-04 1967-01-03 American Home Prod 5-monocyclic aryl-1, 3-dihydro-2h-1, 4-benzodiazepin-2-ones
US4412952A (en) * 1982-04-30 1983-11-01 Sandoz, Inc. Process for 3-hydroxy benzodiazepinones

Also Published As

Publication number Publication date
WO2010046929A2 (en) 2010-04-29

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