WO2010018996A3 - 인간 신경줄기세포 및 이를 이용한 중추 또는 말초 신경계 질환 및 손상 치료용 약학적 조성물 - Google Patents

인간 신경줄기세포 및 이를 이용한 중추 또는 말초 신경계 질환 및 손상 치료용 약학적 조성물 Download PDF

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WO2010018996A3
WO2010018996A3 PCT/KR2009/004504 KR2009004504W WO2010018996A3 WO 2010018996 A3 WO2010018996 A3 WO 2010018996A3 KR 2009004504 W KR2009004504 W KR 2009004504W WO 2010018996 A3 WO2010018996 A3 WO 2010018996A3
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injuries
neural stem
system disorders
treatment
stem cell
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WO2010018996A2 (ko
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박국인
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연세대학교 산학협력단
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Priority to US12/994,953 priority Critical patent/US20110076256A1/en
Priority to JP2011511526A priority patent/JP2011521639A/ja
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Publication of WO2010018996A3 publication Critical patent/WO2010018996A3/ko

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Abstract

본 발명은 인간 신경줄기세포 및 이를 이용한 신경계 질환 및 손상 치료용 약학적 조성물에 관한 것이다. 보다 상세하게는, 본 발명은 신경계 질환 및 손상의 치료에 효과적인 인간 종뇌 유래 인간 신경줄기세포 및 이를 이용한 신경계 질환 및 손상 치료용 약학적 조성물, 신경계 질환 및 손상 치료제 제조를 위한 상기 인간 신경줄기세포의 용도 및 상기 인간 신경줄기세포를 이를 필요로 하는 개체에 유효량으로 투여하는 것을 특징으로 하는 신경계 질환 및 손상 치료방법에 관한 것이다. 본 발명의 인간 신경줄기세포는 신경계 질환 및 손상, 특히 현재 특별한 치료법이 없으며 영구적 신경학적 후유증을 남기는 중증 척수 손상 환자, 허혈성 뇌손상, 간질 및 알츠하이머병의 치료에 유효한 효과를 가진다. 따라서, 본 발명의 인간 신경줄기세포를 포함하는 약학적 조성물은 신경계 손상의 치료를 위한 새로운 방법을 제공하는 효과가 있다.
PCT/KR2009/004504 2008-08-12 2009-08-12 인간 신경줄기세포 및 이를 이용한 중추 또는 말초 신경계 질환 및 손상 치료용 약학적 조성물 WO2010018996A2 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/994,953 US20110076256A1 (en) 2008-08-12 2009-08-12 Human Neural Stem Cell and Pharmaceutical Composition for the Treatment of Central or Peripheral Nervous System Disorders or Injuries Using Same
JP2011511526A JP2011521639A (ja) 2008-08-12 2009-08-12 ヒト神経幹細胞及びこれを利用した中枢または末梢神経系疾患及び損傷治療用薬学的組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0078927 2008-08-12
KR20080078927 2008-08-12

Publications (2)

Publication Number Publication Date
WO2010018996A2 WO2010018996A2 (ko) 2010-02-18
WO2010018996A3 true WO2010018996A3 (ko) 2010-07-08

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PCT/KR2009/004504 WO2010018996A2 (ko) 2008-08-12 2009-08-12 인간 신경줄기세포 및 이를 이용한 중추 또는 말초 신경계 질환 및 손상 치료용 약학적 조성물

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Country Link
US (1) US20110076256A1 (ko)
JP (1) JP2011521639A (ko)
KR (1) KR101102483B1 (ko)
WO (1) WO2010018996A2 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2562111C2 (ru) 2010-08-19 2015-09-10 Ф.Хоффманн-Ля Рош Аг Конверсия соматических клеток в индуцированные репрограмированные нейрональные стволовые клетки (ирнск)
WO2013122408A1 (ko) 2012-02-15 2013-08-22 고려대학교 산학협력단 신경교세포 생성 조절에 관여하는 fam19a5의 약제학적 용도
US8916339B1 (en) 2013-10-31 2014-12-23 Vivex Biomedical, Inc. Spinal cord tissue dehydrated and micronized
CA2964927C (en) * 2014-10-20 2019-07-30 Neuralstem, Inc. Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods of use thereof
KR101895648B1 (ko) 2014-11-06 2018-09-05 단국대학교 천안캠퍼스 산학협력단 치수줄기세포를 포함하는 신경질환 치료용 약학 조성물 및 이의 제조방법
US9402869B1 (en) 2015-03-27 2016-08-02 Vivex Biomedical, Inc. Treated neural tissue composition
KR101816103B1 (ko) 2015-04-13 2018-01-08 고려대학교 산학협력단 소분자 화합물을 이용한 인간 섬유아세포를 신경줄기세포로 직접 전환하는 방법
CN108624560B (zh) * 2018-06-01 2022-04-08 南京艾尔普再生医学科技有限公司 一种分化培养基及少突胶质前体细胞的制备方法
CN110859854A (zh) * 2018-08-08 2020-03-06 上海市东方医院 治疗神经源性肌肉萎缩的药物组合物及其制法和应用

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WO2007061805A2 (en) * 2005-11-17 2007-05-31 The Cleveland Clinic Foundation Multipotent neural stem cells

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Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2000009668A1 (en) * 1998-08-14 2000-02-24 The Children's Medical Center Corporation Engraftable human neural stem cells
WO2007061805A2 (en) * 2005-11-17 2007-05-31 The Cleveland Clinic Foundation Multipotent neural stem cells

Non-Patent Citations (1)

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WO2010018996A2 (ko) 2010-02-18
US20110076256A1 (en) 2011-03-31
JP2011521639A (ja) 2011-07-28
KR101102483B1 (ko) 2012-01-05
KR20100020445A (ko) 2010-02-22

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