WO2010003645A1 - Formulations avec des enrobages de polycarbohydrate-siloxane, leur production et utilisation - Google Patents
Formulations avec des enrobages de polycarbohydrate-siloxane, leur production et utilisation Download PDFInfo
- Publication number
- WO2010003645A1 WO2010003645A1 PCT/EP2009/004915 EP2009004915W WO2010003645A1 WO 2010003645 A1 WO2010003645 A1 WO 2010003645A1 EP 2009004915 W EP2009004915 W EP 2009004915W WO 2010003645 A1 WO2010003645 A1 WO 2010003645A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- active ingredient
- mpcs
- coating
- formulation
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/14—Polymerisation; cross-linking
- B01J13/18—In situ polymerisation with all reactants being present in the same phase
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne un enrobage de polycarbohydrate-siloxane maturé (mPCS), une formulation renfermant une ou plusieurs unités de principe actif enrobées de mPCS, qui est efficace pour confiner la libération de l’unité de principe actif à la région duodénale ou intestinale du tube digestif. L’invention a pour objet des procédés de production de telles formulations pharmaceutiques et leur utilisation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EPPCT/EP2008/005520 | 2008-07-07 | ||
PCT/EP2008/005520 WO2010003430A1 (fr) | 2008-07-07 | 2008-07-07 | Formulations avec des revêtements polycarbohydratesiloxanes, leurs production et utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2010003645A1 true WO2010003645A1 (fr) | 2010-01-14 |
Family
ID=40525261
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/005520 WO2010003430A1 (fr) | 2008-07-07 | 2008-07-07 | Formulations avec des revêtements polycarbohydratesiloxanes, leurs production et utilisation |
PCT/EP2009/004915 WO2010003645A1 (fr) | 2008-07-07 | 2009-07-07 | Formulations avec des enrobages de polycarbohydrate-siloxane, leur production et utilisation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/005520 WO2010003430A1 (fr) | 2008-07-07 | 2008-07-07 | Formulations avec des revêtements polycarbohydratesiloxanes, leurs production et utilisation |
Country Status (1)
Country | Link |
---|---|
WO (2) | WO2010003430A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112526038A (zh) * | 2020-12-15 | 2021-03-19 | 河北科技大学 | 一种卡洛芬及其有关物质的检测方法 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2779613C (fr) | 2009-11-02 | 2017-10-10 | Mannkind Corporation | Appareil et methode de cryogranulation d'une composition pharmaceutique |
WO2017205835A1 (fr) | 2016-05-26 | 2017-11-30 | Allergan, Inc. | Production de particules de sel arrondies |
EP3507004A1 (fr) * | 2016-08-30 | 2019-07-10 | Allergan, Inc. | Procédé de fabrication de billes enrobées |
GB201807312D0 (en) * | 2018-05-03 | 2018-06-20 | Index Pharmaceuticals Ab | Formulation |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3922392A (en) * | 1972-05-27 | 1975-11-25 | Merck Patent Gmbh | Process for coating nonporous material with a porous silicon dioxide layer |
FR2364686A1 (fr) * | 1976-09-18 | 1978-04-14 | Merck Patent Gmbh | Compositions contenant de l'anhydride silicique et procede pour leur preparation |
US5510109A (en) * | 1990-11-28 | 1996-04-23 | Matsushita Electric Industrial Co., Ltd. | Antibacterial and antifungal composition |
EP0941761A2 (fr) * | 1998-03-12 | 1999-09-15 | Wacker-Chemie GmbH | Procédé de fabrication de produits microencapsulés à parois en organopolysiloxane |
WO2003066209A1 (fr) * | 2002-02-07 | 2003-08-14 | Dow Corning Corporation | Procede d'encapsulation et compositions encapsulees |
GB2416524A (en) * | 2004-07-24 | 2006-02-01 | Dow Corning | Microcapsules with siloxane walls formed in situ |
-
2008
- 2008-07-07 WO PCT/EP2008/005520 patent/WO2010003430A1/fr active Application Filing
-
2009
- 2009-07-07 WO PCT/EP2009/004915 patent/WO2010003645A1/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3922392A (en) * | 1972-05-27 | 1975-11-25 | Merck Patent Gmbh | Process for coating nonporous material with a porous silicon dioxide layer |
FR2364686A1 (fr) * | 1976-09-18 | 1978-04-14 | Merck Patent Gmbh | Compositions contenant de l'anhydride silicique et procede pour leur preparation |
US5510109A (en) * | 1990-11-28 | 1996-04-23 | Matsushita Electric Industrial Co., Ltd. | Antibacterial and antifungal composition |
EP0941761A2 (fr) * | 1998-03-12 | 1999-09-15 | Wacker-Chemie GmbH | Procédé de fabrication de produits microencapsulés à parois en organopolysiloxane |
WO2003066209A1 (fr) * | 2002-02-07 | 2003-08-14 | Dow Corning Corporation | Procede d'encapsulation et compositions encapsulees |
GB2416524A (en) * | 2004-07-24 | 2006-02-01 | Dow Corning | Microcapsules with siloxane walls formed in situ |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112526038A (zh) * | 2020-12-15 | 2021-03-19 | 河北科技大学 | 一种卡洛芬及其有关物质的检测方法 |
Also Published As
Publication number | Publication date |
---|---|
WO2010003430A1 (fr) | 2010-01-14 |
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