WO2009151899A3 - Préparation de mésylate d’imatinib - Google Patents

Préparation de mésylate d’imatinib Download PDF

Info

Publication number
WO2009151899A3
WO2009151899A3 PCT/US2009/044587 US2009044587W WO2009151899A3 WO 2009151899 A3 WO2009151899 A3 WO 2009151899A3 US 2009044587 W US2009044587 W US 2009044587W WO 2009151899 A3 WO2009151899 A3 WO 2009151899A3
Authority
WO
WIPO (PCT)
Prior art keywords
imatinib mesylate
preparation
hygroscopic
preparing
processes
Prior art date
Application number
PCT/US2009/044587
Other languages
English (en)
Other versions
WO2009151899A2 (fr
Inventor
Rajasekhar Kadaboina
Munaswamy Sekhar Nariyam
Vijay Bhailalbhai Patel
Original Assignee
Dr. Reddy's Laboratories Ltd.
Dr. Reddy's Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc. filed Critical Dr. Reddy's Laboratories Ltd.
Priority to EP09763190A priority Critical patent/EP2291366A4/fr
Publication of WO2009151899A2 publication Critical patent/WO2009151899A2/fr
Publication of WO2009151899A3 publication Critical patent/WO2009151899A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

La présente invention concerne des procédés permettant de préparer un mésylate d’imatinib de forme cristalline alpha non hygroscopique et stable.
PCT/US2009/044587 2008-05-26 2009-05-20 Préparation de mésylate d’imatinib WO2009151899A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09763190A EP2291366A4 (fr) 2008-05-26 2009-05-20 Préparation de mésylate d imatinib

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1285CH2008 2008-05-26
IN1285/CHE/2008 2008-05-26
US9800308P 2008-09-18 2008-09-18
US61/098,003 2008-09-18

Publications (2)

Publication Number Publication Date
WO2009151899A2 WO2009151899A2 (fr) 2009-12-17
WO2009151899A3 true WO2009151899A3 (fr) 2010-02-25

Family

ID=41417346

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/044587 WO2009151899A2 (fr) 2008-05-26 2009-05-20 Préparation de mésylate d’imatinib

Country Status (2)

Country Link
EP (1) EP2291366A4 (fr)
WO (1) WO2009151899A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL390611A1 (pl) * 2010-03-04 2011-09-12 Tomasz Koźluk Sposób otrzymywania polimorficznej formy alfa i nowa forma polimorficzna mesylanu imatinibu
WO2011158255A1 (fr) * 2010-06-16 2011-12-22 Aptuit Laurus Private Limited Procédé pour la préparation de forme alpha de mésylate d'imatinib stable
EA024088B1 (ru) * 2010-06-18 2016-08-31 КРКА, д.д., НОВО МЕСТО α-ФОРМА МЕЗИЛАТА ИМАТИНИБА, СПОСОБЫ ЕЕ ПОЛУЧЕНИЯ И СОДЕРЖАЩАЯ ЕЁ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ
EP2598499A2 (fr) * 2010-07-29 2013-06-05 Dr. Reddy's Laboratories Ltd. Procédé de préparation de mésylate d'imatinib
WO2012014000A1 (fr) * 2010-07-30 2012-02-02 Ramesh Babu Potluri Forme cristalline α stable de mésylate d'imatinib et son procédé de synthèse
CN102477031B (zh) 2010-11-30 2015-07-15 浙江九洲药业股份有限公司 一种甲磺酸伊马替尼α晶型的制备方法
JP2014509642A (ja) 2011-03-31 2014-04-21 アイエヌディー−スイフト ラボラトリーズ リミテッド イマチニブ及びそのメシル酸塩の生成のための改良方法
ITMI20111309A1 (it) 2011-07-14 2013-01-15 Italiana Sint Spa Procedimento di preparazione di imatinib mesilato
WO2013136141A1 (fr) 2012-03-13 2013-09-19 Fresenius Kabi Oncology Ltd. Procédé amélioré pour la préparation de la forme alpha de mésylate d'imatinib
EP2749557A1 (fr) 2012-12-31 2014-07-02 Deva Holding Anonim Sirketi Procédé de préparation d'alpha forme polymorphe de mesylate d'imatinib de isopropanol et THF solvatés de mésylate d'imatinib
US20160122315A1 (en) * 2013-06-12 2016-05-05 Shilpa Medicare Limited Crystalline imatinib mesylate process
EP2927223B1 (fr) 2014-04-04 2016-06-29 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Procédé de préparation de l'imatinib et de ses sels, exempt d'impureté génotoxique f

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106326A1 (fr) * 2003-06-02 2004-12-09 Hetero Drugs Limited Nouveaux polymorphismes du mesylate d'imatinib
WO2006024863A1 (fr) * 2004-09-02 2006-03-09 Cipla Limited Forme cristalline stable d'imatinib mesylate et son procede de preparation
US20060223816A1 (en) * 2006-05-08 2006-10-05 Chemagis Ltd. Imatinib mesylate alpha form and production process therefor
US20080090833A1 (en) * 2006-04-27 2008-04-17 Alexandr Jegorov Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form alpha

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106326A1 (fr) * 2003-06-02 2004-12-09 Hetero Drugs Limited Nouveaux polymorphismes du mesylate d'imatinib
WO2006024863A1 (fr) * 2004-09-02 2006-03-09 Cipla Limited Forme cristalline stable d'imatinib mesylate et son procede de preparation
US20080090833A1 (en) * 2006-04-27 2008-04-17 Alexandr Jegorov Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form alpha
US20060223816A1 (en) * 2006-05-08 2006-10-05 Chemagis Ltd. Imatinib mesylate alpha form and production process therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2291366A4 *

Also Published As

Publication number Publication date
EP2291366A2 (fr) 2011-03-09
EP2291366A4 (fr) 2012-06-06
WO2009151899A2 (fr) 2009-12-17

Similar Documents

Publication Publication Date Title
WO2009151899A3 (fr) Préparation de mésylate d’imatinib
EP2346837B8 (fr) Procédés de préparation de dérivés de quinazolinone
WO2007136510A3 (fr) FORMES POLYMORPHES DE MÉSYLATE D'IMATINIBE ET PROCÉDÉS DE PRÉPARATION DE NOUVELLES FORMES CRISTALLINES ET AMORPHES ET DE FORME α
WO2010014883A3 (fr) Procédé de préparation d'azacitidine et polymorphes
WO2012015999A3 (fr) Procédé de préparation de mésylate d'imatinib
IL237160A0 (en) Stable amorphous forms of imatinib mesylate
SI2175857T1 (sl) Kristalna oblika (E) 4-((4-((4-(2-cianoetenil)-2,6-dimetilfenil)amino) 2-pirimidinil)amino)benzonitrila
WO2010056656A3 (fr) Synthèse de chlorhydrate de palonosétron cristallin
EP2216333A3 (fr) Formes cristallines du dexlansoprazole
ZA201100760B (en) Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives
HK1201441A1 (en) Process for the preparation of substituted pyrimidine derivatives
WO2010129636A3 (fr) Lénalidomide polymorphe
AU2009254929A8 (en) An improved process for the preparation of amines
WO2011058525A3 (fr) Procédé de synthèse de la forme a du chlorhydrate d'erlotinib et de la forme b du chlorhydrate d'erlotinib
WO2010065586A3 (fr) Préparation de capécitabine
WO2013102919A8 (fr) Formes polymorphes de chlorhydrate d'ivabradine
UA105767C2 (uk) Аморфна форма протіоконазолу, бактерицидна композиція на її основі, способи їх одержання
WO2010039885A3 (fr) Formes cristallines du dexlansoprazole
WO2011023954A3 (fr) Formes polymorphes de manidipine
WO2011018771A3 (fr) Procédé de préparation de chlorhydrate de valganciclovir
WO2010027848A3 (fr) Formes de composés de lapatinib et procédés pour leur préparation
WO2008150481A3 (fr) Procédé de préparation de la forme cristalline bêta d'un mésylate d'imatinibe
WO2009147626A3 (fr) Forme amorphe anhydre de imatinib mesylate
WO2010023676A3 (fr) Procédé de préparation d'une forme polymorphe de lamivudine
IL209152A (en) Methanolic solvate of 2-cyano-2-deoxy-n4-palmitual-1-beta-d-arabinoporenecylcytocin, its crystalline form and processes for its preparation

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09763190

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2009763190

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 7813/CHENP/2010

Country of ref document: IN