WO2009132231A3 - Peptidyl diacylglycerides - Google Patents

Peptidyl diacylglycerides Download PDF

Info

Publication number
WO2009132231A3
WO2009132231A3 PCT/US2009/041595 US2009041595W WO2009132231A3 WO 2009132231 A3 WO2009132231 A3 WO 2009132231A3 US 2009041595 W US2009041595 W US 2009041595W WO 2009132231 A3 WO2009132231 A3 WO 2009132231A3
Authority
WO
WIPO (PCT)
Prior art keywords
diacylglycerides
peptidyl
peptides
peptidyl diacylglycerides
lipopeptides
Prior art date
Application number
PCT/US2009/041595
Other languages
French (fr)
Other versions
WO2009132231A8 (en
WO2009132231A2 (en
Inventor
James D. Thacker
Original Assignee
Therimunex Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therimunex Pharmaceuticals, Inc. filed Critical Therimunex Pharmaceuticals, Inc.
Priority to NZ589365A priority Critical patent/NZ589365A/en
Priority to US12/989,059 priority patent/US9662370B2/en
Priority to JP2011506468A priority patent/JP5802553B2/en
Priority to CA2727973A priority patent/CA2727973C/en
Priority to AU2009240516A priority patent/AU2009240516B2/en
Priority to EP09735391.6A priority patent/EP2293809B1/en
Priority to CN200980124286.1A priority patent/CN102088992B/en
Priority to RU2010147464/10A priority patent/RU2545347C2/en
Publication of WO2009132231A2 publication Critical patent/WO2009132231A2/en
Publication of WO2009132231A3 publication Critical patent/WO2009132231A3/en
Publication of WO2009132231A8 publication Critical patent/WO2009132231A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Abstract

Peptide and peptides that may be covalently linked to a lipid and methods of using such peptides and lipopeptides to prevent or treat disease are disclosed herein.
PCT/US2009/041595 2008-04-24 2009-04-24 Peptidyl diacylglycerides WO2009132231A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
NZ589365A NZ589365A (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides
US12/989,059 US9662370B2 (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides
JP2011506468A JP5802553B2 (en) 2008-04-24 2009-04-24 Peptidyl diacylglyceride
CA2727973A CA2727973C (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides
AU2009240516A AU2009240516B2 (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides
EP09735391.6A EP2293809B1 (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides
CN200980124286.1A CN102088992B (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides
RU2010147464/10A RU2545347C2 (en) 2008-04-24 2009-04-24 Peptidyl-diacylglycerides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4746408P 2008-04-24 2008-04-24
US61/047,464 2008-04-24

Publications (3)

Publication Number Publication Date
WO2009132231A2 WO2009132231A2 (en) 2009-10-29
WO2009132231A3 true WO2009132231A3 (en) 2010-03-11
WO2009132231A8 WO2009132231A8 (en) 2018-11-22

Family

ID=41217423

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/041595 WO2009132231A2 (en) 2008-04-24 2009-04-24 Peptidyl diacylglycerides

Country Status (10)

Country Link
US (1) US9662370B2 (en)
EP (1) EP2293809B1 (en)
JP (1) JP5802553B2 (en)
KR (1) KR20110015571A (en)
CN (1) CN102088992B (en)
AU (1) AU2009240516B2 (en)
CA (1) CA2727973C (en)
NZ (1) NZ589365A (en)
RU (1) RU2545347C2 (en)
WO (1) WO2009132231A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009132231A2 (en) 2008-04-24 2009-10-29 Therimunex Pharmaceuticals, Inc. Peptidyl diacylglycerides
WO2012169911A1 (en) * 2011-06-10 2012-12-13 Auckland Uniservices Limited Peptides, constructs and uses therefor
CN102580609A (en) * 2011-12-29 2012-07-18 华东理工大学 Surfactant and preparation method thereof
US10087221B2 (en) 2013-03-21 2018-10-02 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
DK2976325T3 (en) 2013-03-21 2017-06-06 Sanofi Aventis Deutschland SYNTHESIS OF PEPTIDE PRODUCTS CONTAINING CYCLIC IMID
DE102017115701B4 (en) * 2017-07-12 2022-03-03 Lts Lohmann Therapie-Systeme Ag Fampridine TTS

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256641A (en) * 1990-11-01 1993-10-26 State Of Oregon Covalent polar lipid-peptide conjugates for immunological targeting
US20030109437A1 (en) * 2001-07-19 2003-06-12 Paul Averback Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
US6716963B1 (en) * 1998-05-22 2004-04-06 Abbott Laboratories Peptide antiangiogenic drugs
US20070197436A1 (en) * 2005-07-25 2007-08-23 Thacker James D Peptidyl diacylglycerides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219578A (en) 1991-02-25 1993-06-15 Innovet, Inc. Composition and method for immunostimulation in mammals
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
MX9301789A (en) * 1992-04-03 1993-10-01 Iaf Biochem Int NEW LIPOPHILIC OLIGOPEPTIDES WITH IMMUNOMODULATING ACTIVITY.
US6812339B1 (en) * 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
CN100432103C (en) 2001-07-19 2008-11-12 尼莫克斯股份有限公司 Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells.
RU2259824C2 (en) * 2003-11-06 2005-09-10 Федеральное государственное унитарное предприятие Тихоокеанский научно-исследовательский рыбохозяйственный центр Means possessing lipid-correcting and immunomodulating activity
WO2009132231A2 (en) 2008-04-24 2009-10-29 Therimunex Pharmaceuticals, Inc. Peptidyl diacylglycerides
WO2010118259A1 (en) * 2009-04-10 2010-10-14 Therimunex Pharmaceuticals, Inc. Immunologically active lipopeptides and methods for use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256641A (en) * 1990-11-01 1993-10-26 State Of Oregon Covalent polar lipid-peptide conjugates for immunological targeting
US6716963B1 (en) * 1998-05-22 2004-04-06 Abbott Laboratories Peptide antiangiogenic drugs
US20030109437A1 (en) * 2001-07-19 2003-06-12 Paul Averback Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
US20070197436A1 (en) * 2005-07-25 2007-08-23 Thacker James D Peptidyl diacylglycerides

Also Published As

Publication number Publication date
AU2009240516B2 (en) 2015-06-11
EP2293809A4 (en) 2013-08-21
WO2009132231A8 (en) 2018-11-22
EP2293809B1 (en) 2019-05-15
WO2009132231A2 (en) 2009-10-29
KR20110015571A (en) 2011-02-16
AU2009240516A1 (en) 2009-10-29
CA2727973A1 (en) 2009-10-29
US9662370B2 (en) 2017-05-30
CN102088992A (en) 2011-06-08
EP2293809A2 (en) 2011-03-16
JP2011518840A (en) 2011-06-30
CN102088992B (en) 2016-02-24
RU2545347C2 (en) 2015-03-27
RU2010147464A (en) 2012-05-27
CA2727973C (en) 2019-11-19
NZ589365A (en) 2013-06-28
US20110123611A1 (en) 2011-05-26
JP5802553B2 (en) 2015-10-28

Similar Documents

Publication Publication Date Title
HK1243633A1 (en) Cyclosporine analogue molecules modified at amino acid 1 and 3
WO2009132231A3 (en) Peptidyl diacylglycerides
ZA201104497B (en) Peptide therapeutic conjugates and uses thereof
ZA200804694B (en) Four branched dendrimer-peg for conjugation to proteins and peptides
EP2170363A4 (en) Tissue specific peptide conjugates and methods
WO2008131052A9 (en) Novel peptide amphiphiles having improved solubility and methods of using same
EP2528934A4 (en) Aromatic-cationic peptides and uses of same
IL248880B (en) Compositions comprising r-g-cysteic acid peptides and uses thereof in treating diseases of the eye
IN2012DN03310A (en)
WO2009094172A3 (en) Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
MX345608B (en) Materials and methods for conjugating a water soluble fatty acid derivative to a protein.
EP2330112A4 (en) Collagen peptide, dipeptide, and agent for prevention of disease
WO2008098212A3 (en) Extended release formulations of glucagon and other peptides and proteins
WO2009098682A3 (en) Methods and compositions for treatment of mitochondrial disorders
MX2012009748A (en) Use of transforming growth factor - beta 1 (tgf-î²1) inhibitor peptides for the treatment of corneal fibrosis and/or haze.
WO2007104422A8 (en) Agent-enriched nanoparticles based on hydrophilic proteins
WO2008063808A3 (en) Encapsulated peptide amphiphile nanostructures
WO2008157840A3 (en) Alpha connexin c-terminal (act) peptides for treating age-related macular degeneration
WO2008008884A3 (en) Inhibition of beta-amyloid peptide aggregation
WO2011053789A3 (en) Pharmaceutical composition and methods to enhance cytotoxic t-cell recognition and maintain t-cell memory against a pathogenic disease
WO2007014193A3 (en) Peptidyl diacylglycerides
MX2009003743A (en) Use of modified cyclosporins.
WO2013026021A3 (en) Trka as a target for inhibiting app cleavage and/or progression of alzheimer's disease
WO2012061113A3 (en) Cancer-targeting peptides and uses thereof in cancer treatment and diagnosis
ZA201104614B (en) Hydrophobins as surface active proteins as excipients in solid pharmaceutical formulations

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980124286.1

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09735391

Country of ref document: EP

Kind code of ref document: A2

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2011506468

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2009240516

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 589365

Country of ref document: NZ

Ref document number: 2009735391

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 8236/DELNP/2010

Country of ref document: IN

ENP Entry into the national phase

Ref document number: 20107026279

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2010147464

Country of ref document: RU

ENP Entry into the national phase

Ref document number: 2009240516

Country of ref document: AU

Date of ref document: 20090424

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2727973

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 12989059

Country of ref document: US