WO2009115176A3 - Nanoparticules magnétiques et procédé de fabrication de celles-ci - Google Patents

Nanoparticules magnétiques et procédé de fabrication de celles-ci Download PDF

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Publication number
WO2009115176A3
WO2009115176A3 PCT/EP2009/001356 EP2009001356W WO2009115176A3 WO 2009115176 A3 WO2009115176 A3 WO 2009115176A3 EP 2009001356 W EP2009001356 W EP 2009001356W WO 2009115176 A3 WO2009115176 A3 WO 2009115176A3
Authority
WO
WIPO (PCT)
Prior art keywords
production
magnetic nanoparticles
diameter
relates
present
Prior art date
Application number
PCT/EP2009/001356
Other languages
German (de)
English (en)
Other versions
WO2009115176A2 (fr
Inventor
Achim Schwaemmle
Vera Goelden
Romain Dabre
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Priority to EP09721342A priority Critical patent/EP2254838A2/fr
Publication of WO2009115176A2 publication Critical patent/WO2009115176A2/fr
Publication of WO2009115176A3 publication Critical patent/WO2009115176A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/02—Oxides; Hydroxides
    • C01G49/08—Ferroso-ferric oxide [Fe3O4]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/12—Surface area
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/42—Magnetic properties
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/032—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials
    • H01F1/10—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure
    • H01F1/11—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure in the form of particles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/12—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials
    • H01F1/34—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites
    • H01F1/36—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites in the form of particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Molecular Biology (AREA)
  • Power Engineering (AREA)
  • Composite Materials (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Compounds Of Iron (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Soft Magnetic Materials (AREA)

Abstract

L'invention concerne des nanoparticules magnétiques, notamment des particules de magnétite ayant un diamètre de 10 à 50 nm, et un procédé de fabrication de ces nanoparticules.
PCT/EP2009/001356 2008-03-20 2009-02-26 Nanoparticules magnétiques et procédé de fabrication de celles-ci WO2009115176A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09721342A EP2254838A2 (fr) 2008-03-20 2009-02-26 Nanoparticules magnétiques et procédé de fabrication de celles-ci

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008015365.6 2008-03-20
DE200810015365 DE102008015365A1 (de) 2008-03-20 2008-03-20 Magnetische Nanopartikel und Verfahren zu deren Herstellung

Publications (2)

Publication Number Publication Date
WO2009115176A2 WO2009115176A2 (fr) 2009-09-24
WO2009115176A3 true WO2009115176A3 (fr) 2010-01-14

Family

ID=40983417

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/001356 WO2009115176A2 (fr) 2008-03-20 2009-02-26 Nanoparticules magnétiques et procédé de fabrication de celles-ci

Country Status (3)

Country Link
EP (1) EP2254838A2 (fr)
DE (1) DE102008015365A1 (fr)
WO (1) WO2009115176A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009017943A1 (de) 2009-04-17 2010-10-21 Merck Patent Gmbh Poröse, magnetische Kieselgelformkörper, deren Herstellung und Anwendung
DE102009020208A1 (de) 2009-05-07 2010-11-11 Merck Patent Gmbh Verfahren zum Codieren von Produkten
DE102012014536B4 (de) 2012-07-21 2016-11-24 Perkinelmer Chemagen Technologie Gmbh Sphärische, magnetisierbare Polyvinylalkohol-Mikropartikel, Verfahren für deren Herstellung sowie deren Verwendung
CZ305599B6 (cs) * 2014-08-01 2015-12-30 Univerzita Pardubice Způsob separace biopolymerních molekul a nosič pro využití při tomto způsobu
DE102015215736A1 (de) 2015-08-18 2017-02-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Herstellung von stabil dispergierbaren magnetischen Eisenoxid-Einkern-Nanopartikeln, stabil dispergierbare magnetische Eisenoxid-Einkern-Nanopartikel und Verwendungen hiervon
CZ201843A3 (cs) * 2018-01-29 2019-08-28 Univerzita Pardubice Způsob pro přípravu magnetického kompozitního nosiče na bázi oxidů kovů pro separaci biomolekul

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175734A (en) * 1981-04-21 1982-10-28 Res Inst For Prod Dev Preparation of ultrafine particle of fe3o4
JPS58135135A (ja) * 1982-01-30 1983-08-11 Toda Kogyo Corp 針状晶β−オキシ水酸化鉄粒子粉末の製造法
EP0176919A2 (fr) * 1984-09-28 1986-04-09 BASF Aktiengesellschaft Procédé de préparation de poudre fine de ferrite isotrope à structure spinelle
EP0188765A2 (fr) * 1985-01-09 1986-07-30 Bayer Ag Procédé pour la préparation de pigments d'oxydes de fer magnétiques et isométriques
US4650597A (en) * 1984-05-09 1987-03-17 Basf Aktiengesellschaft Preparation of finely divided isotropic cobalt-containing ferrite powder
US5769937A (en) * 1994-08-26 1998-06-23 Basf Aktiengesellschaft High-purity ferromagnetic iron oxide pigments
EP1225154A2 (fr) * 2001-01-17 2002-07-24 Bayer Aktiengesellschaft Procédé de production de particules de magnétite

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421660A (en) 1980-12-15 1983-12-20 The Dow Chemical Company Colloidal size hydrophobic polymers particulate having discrete particles of an inorganic material dispersed therein
US4452773A (en) 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
FR2624873B1 (fr) 1987-12-18 1992-01-10 Rhone Poulenc Chimie Particules composites magnetisables a base d'organopolysiloxane reticule, leur procede de preparation et leur application en biologie
DE3811042A1 (de) 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
ES2066851T3 (es) 1988-05-24 1995-03-16 Anagen Uk Ltd Particulas atraibles magneticamente y metodo de preparacion.
DE19528029B4 (de) 1995-07-31 2008-01-10 Chemagen Biopolymer-Technologie Aktiengesellschaft Magnetische Polymerpartikel auf der Basis von Polyvinylalkohol, Verfahren für ihre Herstellung und Verwendung
US5789487A (en) 1996-07-10 1998-08-04 Carnegie-Mellon University Preparation of novel homo- and copolymers using atom transfer radical polymerization
WO1998031461A1 (fr) 1997-01-21 1998-07-23 W.R. Grace & Co.-Conn. Adsorbant de silice sur substrat magnetique
US5864025A (en) 1997-06-30 1999-01-26 Virginia Tech Intellectual Properties, Inc. Method of making magnetic, crosslinked chitosan support materials and products thereof
DE19838241A1 (de) 1998-08-22 2000-02-24 Henrik Boettcher Verfahren zur chemischen Modifizierung von Feststoffoberflächen durch "lebende"/kontrollierte Radikalreaktionen

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175734A (en) * 1981-04-21 1982-10-28 Res Inst For Prod Dev Preparation of ultrafine particle of fe3o4
JPS58135135A (ja) * 1982-01-30 1983-08-11 Toda Kogyo Corp 針状晶β−オキシ水酸化鉄粒子粉末の製造法
US4650597A (en) * 1984-05-09 1987-03-17 Basf Aktiengesellschaft Preparation of finely divided isotropic cobalt-containing ferrite powder
EP0176919A2 (fr) * 1984-09-28 1986-04-09 BASF Aktiengesellschaft Procédé de préparation de poudre fine de ferrite isotrope à structure spinelle
EP0188765A2 (fr) * 1985-01-09 1986-07-30 Bayer Ag Procédé pour la préparation de pigments d'oxydes de fer magnétiques et isométriques
US5769937A (en) * 1994-08-26 1998-06-23 Basf Aktiengesellschaft High-purity ferromagnetic iron oxide pigments
EP1225154A2 (fr) * 2001-01-17 2002-07-24 Bayer Aktiengesellschaft Procédé de production de particules de magnétite

Also Published As

Publication number Publication date
DE102008015365A1 (de) 2009-09-24
WO2009115176A2 (fr) 2009-09-24
EP2254838A2 (fr) 2010-12-01

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