WO2009106627A3 - Method for biotechnologically manufacturing itaconic acid - Google Patents

Method for biotechnologically manufacturing itaconic acid Download PDF

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Publication number
WO2009106627A3
WO2009106627A3 PCT/EP2009/052398 EP2009052398W WO2009106627A3 WO 2009106627 A3 WO2009106627 A3 WO 2009106627A3 EP 2009052398 W EP2009052398 W EP 2009052398W WO 2009106627 A3 WO2009106627 A3 WO 2009106627A3
Authority
WO
WIPO (PCT)
Prior art keywords
itaconic acid
manufacturing
biotechnologically
relates
microorganisms
Prior art date
Application number
PCT/EP2009/052398
Other languages
German (de)
French (fr)
Other versions
WO2009106627A2 (en
Inventor
Robert Specht
Andreas Aurich
Eva Kreyss
Gerold Barth
Christian Bodinus
Original Assignee
Helmholtz-Zentrum für Umweltforschung GmbH-UFZ
Technische Universität Dresden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmholtz-Zentrum für Umweltforschung GmbH-UFZ, Technische Universität Dresden filed Critical Helmholtz-Zentrum für Umweltforschung GmbH-UFZ
Publication of WO2009106627A2 publication Critical patent/WO2009106627A2/en
Publication of WO2009106627A3 publication Critical patent/WO2009106627A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention relates to a method for biologically manufacturing itaconic acid formed by microorganisms from corresponding substrates under a regime of oscillating dissolved oxygen concentration in the bioreactor during cultivation. In particular, the invention relates to a method for microbially manufacturing itaconic acid using itaconic acid-producing microorganisms, preferably yeasts, under aerobic submersed conditions.
PCT/EP2009/052398 2008-02-28 2009-02-27 Method for biotechnologically manufacturing itaconic acid WO2009106627A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008011854.0 2008-02-28
DE200810011854 DE102008011854B4 (en) 2008-02-28 2008-02-28 Process for the biotechnological production of itaconic acid

Publications (2)

Publication Number Publication Date
WO2009106627A2 WO2009106627A2 (en) 2009-09-03
WO2009106627A3 true WO2009106627A3 (en) 2010-07-22

Family

ID=40936093

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/052398 WO2009106627A2 (en) 2008-02-28 2009-02-27 Method for biotechnologically manufacturing itaconic acid

Country Status (2)

Country Link
DE (1) DE102008011854B4 (en)
WO (1) WO2009106627A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112218941A (en) 2018-06-07 2021-01-12 巴斯夫欧洲公司 Microbial and fine chemical production

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004028179A1 (en) * 2004-06-04 2006-01-19 Ufz-Umweltforschungszentrum Leipzig-Halle Gmbh Biotechnological preparation of functionalized di- and tri-carboxylic acid e.g. citric acid comprises culturing microorganism (capable of cleaving monocarbonic acid under aerobic condition) in monocarbonic acid culture medium

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5534017A (en) 1978-08-28 1980-03-10 Mitsubishi Chem Ind Ltd Preparation of itaconic acid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004028179A1 (en) * 2004-06-04 2006-01-19 Ufz-Umweltforschungszentrum Leipzig-Halle Gmbh Biotechnological preparation of functionalized di- and tri-carboxylic acid e.g. citric acid comprises culturing microorganism (capable of cleaving monocarbonic acid under aerobic condition) in monocarbonic acid culture medium

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
LEVINSON, W.E. ET AL.: "Production of itaconic acid by Pseudozyma antarctica NRRL Y-7808 under nitrogen-limited growth conditions", ENZYME AND MICROBIAL TECHNOLOGY, vol. 39, no. 4, 2 August 2006 (2006-08-02), pages 824 - 827, XP025095051 *
PARK, Y.S. ET AL.: "Effect of dissolved oxygen concentration and impeller tip speed on itaconic acid production by Aspergillus terreus", BIOTECHNOLOGY LETTERS, vol. 16, no. 6, 1993, pages 583 - 586, XP002570225 *
WELTER, K.: "Biotechnische Produktion von Itaconsäure aus nachwachsenden Rohstoffen mit immobilisierten Zellen", INTERNET, 2000, pages 1 - 144, XP002570226, Retrieved from the Internet <URL:http://deposit.d-nb.de/cgi-bin/dokserv?idn=959655115&dok_var=d1&dok_ext=pdf&filename=959655115.pdf> [retrieved on 20100223] *

Also Published As

Publication number Publication date
DE102008011854B4 (en) 2014-02-20
DE102008011854A1 (en) 2009-09-10
WO2009106627A2 (en) 2009-09-03

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