WO2009104939A3 - 약제학적 제제 - Google Patents
약제학적 제제 Download PDFInfo
- Publication number
- WO2009104939A3 WO2009104939A3 PCT/KR2009/000856 KR2009000856W WO2009104939A3 WO 2009104939 A3 WO2009104939 A3 WO 2009104939A3 KR 2009000856 W KR2009000856 W KR 2009000856W WO 2009104939 A3 WO2009104939 A3 WO 2009104939A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pharmaceutical preparation
- compartment
- compartments
- active component
- hmg
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
본 발명은 약리학적 활성성분으로 레닌억제제를 포함하는 구획, 및 약리학적 활성성분으로 HMG-CoA환원효소억제제를 포함하는 구획을 포함하며, 상기 구획 중 하나의 구획은 선방출성 구획이고 나머지 하나의 구획은 지연방출성 구획인 약제학적 제제를 제공한다. 본 발명의 복합제제는 레닌억제제와 HMG-CoA환원효소억제제를 특정 속도로 시간차를 두고 송달 가능하므로, 부작용의 염려는 감소시키고 약효는 향상시키며, 복약지도는 용이하게 하는 장점을 갖는다. 또한, 상기 약물성분을 따로 또는 동시에 복용하는 복합 처방의 경우보다 대사 증후군, 심혈관 질환, 신장 질환 등의 예방 또는 치료에서 약리학적, 임상학적, 과학적 및 경제적으로 보다 유용한 효과를 달성할 수 있게 한다.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009801144445A CN102014881A (zh) | 2008-02-22 | 2009-02-23 | 药物制剂 |
US12/918,993 US20110111021A1 (en) | 2008-02-22 | 2009-02-23 | Pharmaceutical preparation |
EP09711817A EP2255796A2 (en) | 2008-02-22 | 2009-02-23 | Pharmaceutical preparation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2008-0016518 | 2008-02-22 | ||
KR20080016518 | 2008-02-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009104939A2 WO2009104939A2 (ko) | 2009-08-27 |
WO2009104939A3 true WO2009104939A3 (ko) | 2009-11-19 |
Family
ID=40986074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2009/000856 WO2009104939A2 (ko) | 2008-02-22 | 2009-02-23 | 약제학적 제제 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20110111021A1 (ko) |
EP (1) | EP2255796A2 (ko) |
KR (1) | KR101164300B1 (ko) |
CN (1) | CN102014881A (ko) |
WO (1) | WO2009104939A2 (ko) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2382969A1 (en) * | 2010-04-30 | 2011-11-02 | Sanovel Ilac Sanayi ve Ticaret A.S. | Multicoated Aliskiren formulations |
CN102247345A (zh) * | 2011-05-30 | 2011-11-23 | 北京阜康仁生物制药科技有限公司 | 一种新型降血脂组合物 |
CN102283831B (zh) * | 2011-09-03 | 2014-08-06 | 新乡医学院第一附属医院 | 一种治疗冠心病的西药复方及用途 |
KR20170012169A (ko) * | 2015-07-24 | 2017-02-02 | 김병용 | 경구용 복합제제 |
KR102265977B1 (ko) * | 2018-07-16 | 2021-06-16 | 주식회사 코피텍 | 방습성이 개선된 필름 코팅용 조성물 및 이를 코팅한 정제 |
CN113398273B (zh) * | 2021-05-14 | 2022-07-19 | 广西壮族自治区中国科学院广西植物研究所 | 木聚糖衍生物作为亲水性缓释材料在制备药物缓释片中的应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010022508A (ko) * | 1997-07-31 | 2001-03-15 | 추후보정 | 3-히드록시-3-메틸글루타릴 조효소 a 환원 효소 억제제와니코틴산 화합물의 조성물 및 야간에 1일 1회 투여하여고지질혈증을 치료하는 방법 |
KR20040079980A (ko) * | 2002-02-01 | 2004-09-16 | 데포메드 인코퍼레이티드 | 속방성 및 서방성 약물 모두를 송달하는 경구 투약 형태의제조방법 |
KR20070078625A (ko) * | 2006-01-27 | 2007-08-01 | 씨제이 주식회사 | 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법 |
KR20080000624A (ko) * | 2005-04-27 | 2008-01-02 | 노파르티스 아게 | 아테롬성동맥경화증의 치료 방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY119161A (en) | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
NZ520176A (en) * | 1997-07-31 | 2005-02-25 | Kos Life Sciences Inc | Combinations of HMG-CoA reductase inhibitors and nicotinic acid compounds and methods for treating hyperlipidemia once a day at night |
US8168616B1 (en) | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
US20080103105A1 (en) * | 2006-09-22 | 2008-05-01 | Braincells, Inc. | HMG CoA REDUCTASE MEDIATED MODULATION OF NEUROGENESIS |
-
2009
- 2009-02-23 WO PCT/KR2009/000856 patent/WO2009104939A2/ko active Application Filing
- 2009-02-23 CN CN2009801144445A patent/CN102014881A/zh active Pending
- 2009-02-23 KR KR1020090014956A patent/KR101164300B1/ko not_active IP Right Cessation
- 2009-02-23 EP EP09711817A patent/EP2255796A2/en not_active Withdrawn
- 2009-02-23 US US12/918,993 patent/US20110111021A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010022508A (ko) * | 1997-07-31 | 2001-03-15 | 추후보정 | 3-히드록시-3-메틸글루타릴 조효소 a 환원 효소 억제제와니코틴산 화합물의 조성물 및 야간에 1일 1회 투여하여고지질혈증을 치료하는 방법 |
KR20040079980A (ko) * | 2002-02-01 | 2004-09-16 | 데포메드 인코퍼레이티드 | 속방성 및 서방성 약물 모두를 송달하는 경구 투약 형태의제조방법 |
KR20080000624A (ko) * | 2005-04-27 | 2008-01-02 | 노파르티스 아게 | 아테롬성동맥경화증의 치료 방법 |
KR20070078625A (ko) * | 2006-01-27 | 2007-08-01 | 씨제이 주식회사 | 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법 |
Also Published As
Publication number | Publication date |
---|---|
WO2009104939A2 (ko) | 2009-08-27 |
US20110111021A1 (en) | 2011-05-12 |
EP2255796A2 (en) | 2010-12-01 |
KR20090091081A (ko) | 2009-08-26 |
CN102014881A (zh) | 2011-04-13 |
KR101164300B1 (ko) | 2012-07-09 |
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