WO2009101472A3 - Stent coated with aligned nanofiber by electrospinning - Google Patents

Stent coated with aligned nanofiber by electrospinning Download PDF

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Publication number
WO2009101472A3
WO2009101472A3 PCT/IB2008/003867 IB2008003867W WO2009101472A3 WO 2009101472 A3 WO2009101472 A3 WO 2009101472A3 IB 2008003867 W IB2008003867 W IB 2008003867W WO 2009101472 A3 WO2009101472 A3 WO 2009101472A3
Authority
WO
WIPO (PCT)
Prior art keywords
stent
electrospinning
nanofibers
aligned
stent coated
Prior art date
Application number
PCT/IB2008/003867
Other languages
French (fr)
Other versions
WO2009101472A2 (en
Inventor
Kwan-Ho Chan
Yixiang Dong
Wee Eong Teo
Seeram Ramakrishna
Original Assignee
National University Of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University Of Singapore filed Critical National University Of Singapore
Publication of WO2009101472A2 publication Critical patent/WO2009101472A2/en
Publication of WO2009101472A3 publication Critical patent/WO2009101472A3/en

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/78—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from copolycondensation products
    • D01F6/84—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from copolycondensation products from copolyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D01D5/0076—Electro-spinning characterised by the electro-spinning apparatus characterised by the collecting device, e.g. drum, wheel, endless belt, plate or grid
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
    • D01D5/0076—Electro-spinning characterised by the electro-spinning apparatus characterised by the collecting device, e.g. drum, wheel, endless belt, plate or grid
    • D01D5/0084—Coating by electro-spinning, i.e. the electro-spun fibres are not removed from the collecting device but remain integral with it, e.g. coating of prostheses
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D7/00—Collecting the newly-spun products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

Abstract

A stent is covered with a coating that comprises nanofibers that are substantially aligned with the longitudinal axis of the stent's tubular body. The nanofibers may be deposited on the stent using an electrospinning process, which may deposit aligned nanofibers onto a collector and then transfer the aligned nanofibers to the stent, or deposit aligned nanofibers directly onto the stent.
PCT/IB2008/003867 2007-11-02 2008-11-03 Stent coated with aligned nanofiber by electrospinning WO2009101472A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98480307P 2007-11-02 2007-11-02
US60/984,803 2007-11-02

Publications (2)

Publication Number Publication Date
WO2009101472A2 WO2009101472A2 (en) 2009-08-20
WO2009101472A3 true WO2009101472A3 (en) 2009-10-08

Family

ID=40957319

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/003867 WO2009101472A2 (en) 2007-11-02 2008-11-03 Stent coated with aligned nanofiber by electrospinning

Country Status (1)

Country Link
WO (1) WO2009101472A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8057535B2 (en) 2007-06-11 2011-11-15 Nano Vasc, Inc. Implantable medical device
CN106574412A (en) * 2014-08-18 2017-04-19 美国俄克拉荷马州立中央大学 Method and apparatus for controlled alignment and deposition of branched electrospun fiber

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090082856A1 (en) * 2007-09-21 2009-03-26 Boston Scientific Scimed, Inc. Medical devices having nanofiber-textured surfaces
CZ201093A3 (en) * 2010-02-05 2011-08-17 Cpn S.R.O. Device for producing two-dimensional or three-dimensional fibrous materials from microfibers or nanofibers
DE102010025302B4 (en) 2010-06-28 2012-09-13 Gottfried Wilhelm Leibniz Universität Hannover Method of making a stent with electrospun fiber coating
CN102181948A (en) * 2011-05-23 2011-09-14 北京化工大学 Electrostatic spinning method and electrostatic spinning device for preparing nano fiber with one-dimensional order structure
KR101324772B1 (en) * 2011-05-24 2013-11-06 서울대학교산학협력단 An esophageal stent for controlled delivery of a drug and a preparation method thereof
CN102430157B (en) * 2011-11-29 2013-11-27 武汉纺织大学 Medical scaffold with inner coating film, and preparation method for medical scaffold
CN103343393B (en) * 2013-07-24 2016-01-20 苏州大学 A kind of electrostatic spinning apparatus of three-dimensional manometer fibre assemblies and method
CN103334168B (en) * 2013-07-24 2016-01-20 苏州大学 A kind of receiving system of electrostatic spinning
WO2015075658A1 (en) 2013-11-20 2015-05-28 The Stellenbosch Nanofiber Company (Pty) Limited Electrospun fibre collection and handling
US10633766B2 (en) 2014-08-18 2020-04-28 University of Central Oklahoma Method and apparatus for collecting cross-aligned fiber threads
US10932910B2 (en) 2014-08-18 2021-03-02 University of Central Oklahoma Nanofiber coating to improve biological and mechanical performance of joint prosthesis
US9809906B2 (en) 2014-08-18 2017-11-07 University of Central Oklahoma Method and apparatus to coat a metal implant with electrospun nanofiber matrix
US10415156B2 (en) 2014-08-18 2019-09-17 University of Central Oklahoma Method and apparatus for controlled alignment and deposition of branched electrospun fiber
US11058521B2 (en) 2014-08-18 2021-07-13 University of Central Oklahoma Method and apparatus for improving osseointegration, functional load, and overall strength of intraosseous implants
CN105232181B (en) * 2015-09-23 2018-06-01 苏州大学 A kind of device for preparing medical tubular rack
WO2017147183A1 (en) 2016-02-23 2017-08-31 University of Central Oklahoma Process to create 3d tissue scaffold using electrospun nanofiber matrix and photosensitive hydrogel
WO2017156531A1 (en) * 2016-03-11 2017-09-14 The Johns Hopkins University Ultra-thin, high strength, drug-loaded sutures and coatings thereof
US20200087818A1 (en) * 2017-03-15 2020-03-19 Ohio State Innovation Foundation Three dimensional printing modality combining fused deposition modeling and electrospinning
EP3740255A4 (en) * 2018-01-15 2021-10-06 Technion Research & Development Foundation Limited Electrospun-coated medical devices
CN108103598A (en) * 2018-02-09 2018-06-01 郑州大学 A kind of electrostatic spinning reception device for preparing axial orientation tubular tissue engineering material

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211135A1 (en) * 2002-04-11 2003-11-13 Greenhalgh Skott E. Stent having electrospun covering and method
US20040030377A1 (en) * 2001-10-19 2004-02-12 Alexander Dubson Medicated polymer-coated stent assembly
WO2005079339A2 (en) * 2004-02-12 2005-09-01 The University Of Akron Improved stent for use in arteries
SE530751C2 (en) * 2007-02-20 2008-09-02 Ifp Res Ab Device for making nanofibre

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040030377A1 (en) * 2001-10-19 2004-02-12 Alexander Dubson Medicated polymer-coated stent assembly
US20030211135A1 (en) * 2002-04-11 2003-11-13 Greenhalgh Skott E. Stent having electrospun covering and method
WO2005079339A2 (en) * 2004-02-12 2005-09-01 The University Of Akron Improved stent for use in arteries
SE530751C2 (en) * 2007-02-20 2008-09-02 Ifp Res Ab Device for making nanofibre

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MO, X. M. ET AL: "Electrospun P(LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation", BIOMATERIALS, vol. 25, no. 10, May 2004 (2004-05-01), pages 1883 - 1890 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8057535B2 (en) 2007-06-11 2011-11-15 Nano Vasc, Inc. Implantable medical device
CN106574412A (en) * 2014-08-18 2017-04-19 美国俄克拉荷马州立中央大学 Method and apparatus for controlled alignment and deposition of branched electrospun fiber

Also Published As

Publication number Publication date
WO2009101472A2 (en) 2009-08-20

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