WO2009091230A3 - 유방암 모니터링,진단 및 스크리닝용 단백질 마커 및 이를 이용한 유방암 모니터링,진단 및 스크리닝 방법 - Google Patents

유방암 모니터링,진단 및 스크리닝용 단백질 마커 및 이를 이용한 유방암 모니터링,진단 및 스크리닝 방법 Download PDF

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WO2009091230A3
WO2009091230A3 PCT/KR2009/000279 KR2009000279W WO2009091230A3 WO 2009091230 A3 WO2009091230 A3 WO 2009091230A3 KR 2009000279 W KR2009000279 W KR 2009000279W WO 2009091230 A3 WO2009091230 A3 WO 2009091230A3
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breast
cancer
diagnosis
screening
monitoring
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PCT/KR2009/000279
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English (en)
French (fr)
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WO2009091230A2 (ko
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김철우
박필제
이경애
강경남
신용성
노동영
김병권
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주식회사 바이오인프라
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Publication of WO2009091230A2 publication Critical patent/WO2009091230A2/ko
Publication of WO2009091230A3 publication Critical patent/WO2009091230A3/ko

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

본 발명은 유방암 모니터링, 진단 및 스크리닝용 단백질 마커, 및 이를 이용한 유방암 모니터링, 진단 및 스크리닝 방법에 관한 것으로, 보다 상세하게는 유방암 환자에게서 특이적으로 발현이 증가 또는 감소하는 단백질 마커를 이용하여 유방암을 모니터링, 진단 및 스크리닝하는 방법에 관한 것이다. 본 발명의 단백질 마커를 이용한 유방암 모니터링, 진단 및 스크리닝 방법은 정상인과 유방암 환자에서 마커 단백질 발현량의 차이를 확인하여 유방암의 조기 진단 및 스크리닝, 및 유방암 진행 정도 평가를 가능하게 함으로써 신속한 치료가 가능하게 하여 유방암 환자의 생존율을 향상시키고 암 치료로 인한 국가적 손실을 줄이는데 기여할 수 있다.
PCT/KR2009/000279 2008-01-18 2009-01-19 유방암 모니터링,진단 및 스크리닝용 단백질 마커 및 이를 이용한 유방암 모니터링,진단 및 스크리닝 방법 WO2009091230A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20080005693 2008-01-18
KR10-2008-0005693 2008-01-18

Publications (2)

Publication Number Publication Date
WO2009091230A2 WO2009091230A2 (ko) 2009-07-23
WO2009091230A3 true WO2009091230A3 (ko) 2009-10-08

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PCT/KR2009/000279 WO2009091230A2 (ko) 2008-01-18 2009-01-19 유방암 모니터링,진단 및 스크리닝용 단백질 마커 및 이를 이용한 유방암 모니터링,진단 및 스크리닝 방법

Country Status (2)

Country Link
KR (1) KR101122647B1 (ko)
WO (1) WO2009091230A2 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101144323B1 (ko) * 2009-12-30 2012-05-11 한국과학기술연구원 유방암 진단용 자가항체마커 및 이의 조합으로 구성된 다중마커진단 키트
KR101142443B1 (ko) * 2010-05-18 2012-05-11 한국생명공학연구원 폐암 진단용 Col10A1 마커 및 이를 이용한 진단 키트
AU2012327215A1 (en) * 2011-02-16 2013-09-26 The Gov't of the USA, as represented by The Sec'y, Dept of Hlth and Hum'n Srvcs, Ctrs for Disease Ctrl & Prvn Detection of subject biomarker diagnostic assay for dengue fever and the differentiation of dengue hemorrhagic fever
KR101431062B1 (ko) * 2012-03-08 2014-08-21 (주)바이오메디앙 유방암 진단용 다중 바이오마커 세트, 이의 검출 방법 및 이에 대한 항체를 포함하는 유방암 진단키트
CN110716043B (zh) * 2019-10-23 2023-02-28 郑州大学 一种用于乳腺癌早期筛查和诊断的血清蛋白标志物、试剂盒及检测方法
CN111190008B (zh) * 2020-01-07 2022-03-11 中山大学孙逸仙纪念医院 血清mpo-dna在预测乳腺癌预后抑制乳腺癌远处器官转移中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050100371A (ko) * 2003-01-13 2005-10-18 에모리 유니버시티 정상 및 암세포에서의 유전자 발현의 검출 방법
KR100679173B1 (ko) * 2006-02-28 2007-02-06 주식회사 바이오인프라 위암 진단용 단백질 마커 및 이를 이용한 진단키트
US20070117123A1 (en) * 2005-09-14 2007-05-24 The Regents Of The University Of California Salivary protein and rna for breast cancer detection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050100371A (ko) * 2003-01-13 2005-10-18 에모리 유니버시티 정상 및 암세포에서의 유전자 발현의 검출 방법
US20070117123A1 (en) * 2005-09-14 2007-05-24 The Regents Of The University Of California Salivary protein and rna for breast cancer detection
KR100679173B1 (ko) * 2006-02-28 2007-02-06 주식회사 바이오인프라 위암 진단용 단백질 마커 및 이를 이용한 진단키트

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEELIMA DENDULURI ET AL.: "Circulating biomarkers of bevacizumab activity in patients with breast cancer.", CANCER BIOLOGY & THERAPY., vol. 7, no. 1, 1 January 2008 (2008-01-01), pages 15 - 20 *

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Publication number Publication date
KR20090079845A (ko) 2009-07-22
WO2009091230A2 (ko) 2009-07-23
KR101122647B1 (ko) 2012-03-13

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